Sorex araneus (European shrew): 101547055 Help Entry 101547055         CDS       T07854                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism sara  Sorex araneus (European shrew) Pathway sara00230   Purine metabolism sara01100   Metabolic pathways sara01522   Endocrine resistance sara04015   Rap1 signaling pathway sara04020   Calcium signaling pathway sara04022   cGMP-PKG signaling pathway sara04024   cAMP signaling pathway sara04062   Chemokine signaling pathway sara04072   Phospholipase D signaling pathway sara04081   Hormone signaling sara04082   Neuroactive ligand signaling sara04114   Oocyte meiosis sara04211   Longevity regulating pathway sara04213   Longevity regulating pathway - multiple species sara04261   Adrenergic signaling in cardiomyocytes sara04270   Vascular smooth muscle contraction sara04371   Apelin signaling pathway sara04540   Gap junction sara04611   Platelet activation sara04713   Circadian entrainment sara04714   Thermogenesis sara04723   Retrograde endocannabinoid signaling sara04724   Glutamatergic synapse sara04725   Cholinergic synapse sara04727   GABAergic synapse sara04740   Olfactory transduction sara04750   Inflammatory mediator regulation of TRP channels sara04911   Insulin secretion sara04912   GnRH signaling pathway sara04913   Ovarian steroidogenesis sara04914   Progesterone-mediated oocyte maturation sara04915   Estrogen signaling pathway sara04916   Melanogenesis sara04918   Thyroid hormone synthesis sara04921   Oxytocin signaling pathway sara04923   Regulation of lipolysis in adipocytes sara04925   Aldosterone synthesis and secretion sara04926   Relaxin signaling pathway sara04927   Cortisol synthesis and secretion sara04928   Parathyroid hormone synthesis, secretion and action sara04934   Cushing syndrome sara04935   Growth hormone synthesis, secretion and action sara04962   Vasopressin-regulated water reabsorption sara04970   Salivary secretion sara04971   Gastric acid secretion sara04972   Pancreatic secretion sara04976   Bile secretion sara05032   Morphine addiction sara05163   Human cytomegalovirus infection sara05166   Human T-cell leukemia virus 1 infection sara05200   Pathways in cancer sara05207   Chemical carcinogenesis - receptor activation sara05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:sara00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     101547055 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     101547055 (ADCY3)    04371 Apelin signaling pathway     101547055 (ADCY3)    04020 Calcium signaling pathway     101547055 (ADCY3)    04072 Phospholipase D signaling pathway     101547055 (ADCY3)    04024 cAMP signaling pathway     101547055 (ADCY3)    04022 cGMP-PKG signaling pathway     101547055 (ADCY3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     101547055 (ADCY3)    04081 Hormone signaling     101547055 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     101547055 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     101547055 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     101547055 (ADCY3)    04062 Chemokine signaling pathway     101547055 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     101547055 (ADCY3)    04923 Regulation of lipolysis in adipocytes     101547055 (ADCY3)    04912 GnRH signaling pathway     101547055 (ADCY3)    04913 Ovarian steroidogenesis     101547055 (ADCY3)    04915 Estrogen signaling pathway     101547055 (ADCY3)    04914 Progesterone-mediated oocyte maturation     101547055 (ADCY3)    04921 Oxytocin signaling pathway     101547055 (ADCY3)    04926 Relaxin signaling pathway     101547055 (ADCY3)    04935 Growth hormone synthesis, secretion and action     101547055 (ADCY3)    04918 Thyroid hormone synthesis     101547055 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     101547055 (ADCY3)    04916 Melanogenesis     101547055 (ADCY3)    04925 Aldosterone synthesis and secretion     101547055 (ADCY3)    04927 Cortisol synthesis and secretion     101547055 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     101547055 (ADCY3)    04270 Vascular smooth muscle contraction     101547055 (ADCY3)   09154 Digestive system    04970 Salivary secretion     101547055 (ADCY3)    04971 Gastric acid secretion     101547055 (ADCY3)    04972 Pancreatic secretion     101547055 (ADCY3)    04976 Bile secretion     101547055 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     101547055 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     101547055 (ADCY3)    04727 GABAergic synapse     101547055 (ADCY3)    04725 Cholinergic synapse     101547055 (ADCY3)    04723 Retrograde endocannabinoid signaling     101547055 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     101547055 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     101547055 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     101547055 (ADCY3)    04213 Longevity regulating pathway - multiple species     101547055 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     101547055 (ADCY3)    04714 Thermogenesis     101547055 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101547055 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     101547055 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101547055 (ADCY3)    05163 Human cytomegalovirus infection     101547055 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     101547055 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     101547055 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     101547055 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     101547055 (ADCY3) Enzymes [BR:sara01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      101547055 (ADCY3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Motif Other DBs NCBI-GeneID:  101547055 NCBI-ProteinID:  XP_012788375 LinkDB All DBs Position Unknown AA seq 1102 aa AA seqDB search MPRNQGFSDPEYSAEYSAEYSASLPSDADRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE SLESLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFAGDKLAPLLVAAVGLVLDII LFVLCKKGLLPDRVSRKVVPYLLWLLITAEIFSYLGLNFARAHALSDTVGWQAFFVFSYF ITLPLSLSPIVIISVLACVLHTVVLAVTVAQQQQDRLNGTLLLREILANVFLYLGAIIVG IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQQHLLPPLLPGHRVAPRVSLWRRRKC PFSPQGALGLASGRSLRYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAIRF VREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMESGGIPGRVHISQST MDCLKGEFDVEPGDGGSRCDYLDEKGIETYLVIASGPYVKKNSQAGSVPNGLPTASRPNT PILIDTDTKEPNGDAHTSGSTTEEPGEQETEADNPAFPNPRRRLRLQDLADRVVDASQDE HELNQLLNEALLERESAQVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVL FCTALVETLIDPWLMTNYVTFVVGEVLLLVLTICSLASIFPRNFPKKLVAFSIWIDRTRW ARNTWAMLAIFILVMANVVDMLSCLQYYTGVSNVTAGPEVVDGCVQNPKYYNYVAVLSLV ACIMLVQVSHMVKLTLMLLVSGAVAVVNIYAWRPIFDDYDRWRFQENDFPMVALEKMQVL PAPMLNGTDSLPLVPSKYSMTVMILVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVY EMRRWNEALVTNMLPEHVARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEEAIN NGGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPEVNTNGFTGSNKD EKSDKERWQHLADLADFALAMKDTLTHINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYD IWGNTVNVASRMESTGVMGNIQVVEETQIILREYGFRFVRRGPIFVKGKGELLTFFLKGR DKPAAFPNGSSVTLPHQVVDNP NT seq 3309 nt NT seq  +upstreamnt  +downstreamnt atgcctcggaaccagggcttctccgaccccgagtactcggcggagtactcggccgagtac tcggcgagcctgccctctgacgccgaccgtggggtgggccggacccatgagatctccgtg cggaactcggggtcgtgcctgtgcctgccccgctttatgcggctgaccttcgtgcccgag tccctggagagcctctaccagacctacttcaagcggcagcgccacgagacactgctggtg ctggtggtcttcgccgccctcttcgactgctacgtggtggtcatgtgcgccgtggtcttc gcgggcgacaagctggcgccgctgctggtggcggccgtggggctggtgttggacatcatc ctcttcgtgctgtgcaagaaggggctgctccccgaccgcgtgagccgcaaggtggtgccg tacctgctgtggctgctgatcacggccgagatcttctcctacctgggcctgaacttcgcc cgcgcgcacgcgctcagcgacacggtgggctggcaggccttcttcgtcttctcctacttc atcacgctgccgctcagcctcagccccatcgtcatcatctccgtgctggcctgcgtgctg cacacagtcgtcctggccgtcaccgtggcccagcagcagcaggacaggctcaacgggacc ctcttgctgagggagatcctggccaacgtcttcctatacctcggcgccatcatcgtgggc atcatgtcctactacatggctgaccgcaagcaccgcaaggccttcctggaggcccgccag tcgctggaggtgaagatgaacctggaggagcagagccagcagcagcagcacctcctccct cctctgctccccggacaccgagtggcccctcgtgtttctctgtggcgcagacgcaaatgc ccgttttctcctcagggcgcgctgggccttgcgagcggacggagtctaaggtaccaccag ctgcgcatcaagatcctgggcgactgctactactgcatctgcgggctgcccgactaccgc gaggaccacgccgtctgctccatcctcatggggctcgccatggtcgaggccatccggttt gtgcgcgagaagaccaagacgggggtggacatgcgcgtgggggtgcacacgggcaccgtg ctgggcggcgtcctgggccagaagcgctggcagtacgacgtgtggtccacggacgtgact gtggccaacaagatggagtctgggggcatcccagggcgcgtgcacatctcccagagcacc atggactgcctgaagggcgagtttgacgtggagccgggggacgggggcagccgctgcgac tacctggacgagaagggcattgagacctacctggtcatcgcgtccgggccctacgtgaag aaaaactcccaggccggctcggtgcccaatggcctgcccaccgcctcgaggcccaacacc ccgatcctcatcgataccgacaccaaggagcccaacggcgacgcccacaccagcggctcc acgacggaggagcccggggagcaggagaccgaggccgacaaccccgcctttcccaacccc cgccggaggctgcgcctgcaggacctggctgaccgcgtggtggacgcgtctcaggacgag cacgagctcaaccagctcctcaacgaggcgctgctggagcgcgagtctgcgcaggtggtg aagaagagaaacaccttcctcctgtccatgcgcttcatggaccccgagatggagacgcgc tactcggtggagaaggagaagcagagcggggccgccttcagctgctcctgcgtggtcctg ttctgcacggcgctcgtggagaccctcatcgacccctggctcatgaccaactatgtgacc ttcgtggtgggggaggttctgctcctggtcctgaccatctgctcactggcttccatcttt ccccggaactttcctaagaagctcgtggccttttctatttggattgaccggacccgctgg gccaggaacacatgggccatgttagccatcttcatcctggtcatggccaacgtggtggac atgctgagctgcctccagtactacacaggcgtcagcaacgtcaccgcaggcccggaggtg gtggacggctgcgtgcagaaccccaagtattacaactacgtggccgtgctgtcgctggtc gcctgcatcatgctggtgcaggtcagccacatggtgaagctcacgctcatgctgctggtc tcgggcgccgtggccgtcgtcaacatctatgcctggcgccccatcttcgacgactacgac cgctggcgcttccaggagaacgacttccccatggttgccttggagaagatgcaggtgctt cccgccccgatgctcaatggcaccgacagcctgcccctcgtgccatccaagtactccatg accgtgatgatcctcgtcatgatgctcagcttttactacttctcccgccacgtggagaaa ctggcacggacgctgttcctctggaagattgaggtccacgaccagaaggagcgggtctac gaaatgcgacgctggaacgaggccttggtcaccaacatgctgcctgagcacgtggcacgc cacttcctgggctccaagaagagggacgaggagctctacagccagtcctacgacgagatc ggagtcatgttcgcctccctgcccaacttcgccgacttctacacagaggaggccatcaac aacggcggcatcgagtgtctgcgcttcctcaacgagatcatctcggacttcgactctctc ctggacaaccccaaattccgggtcatcaccaagatcaagaccattggcagcacctacatg gcagcttctggagtgaccccagaagtcaacaccaatggcttcactggttccaacaaggac gagaagtcggacaaggagcgctggcagcacctggcggacctggcggacttcgcgctggcc atgaaggacacgctcacacacatcaacaaccagtccttcaacaacttcatgctgcgcatc ggcatgaacaaaggcggggtgctggccggggtcatcggggcccggaagccacactatgac atctggggcaataccgtcaacgtggccagcaggatggagtccacgggagtcatgggcaac attcaggtggtggaggagacacagatcatcctgcgcgagtacggcttccgcttcgtgcgc cgcgggcccatcttcgtcaagggcaagggcgagctgctgaccttcttcctcaagggccga gacaaaccggccgccttccccaacgggtcctcggtgacgctgccccaccaggtggtggac aacccctga

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