Sorex araneus (European shrew): 101548820 Help Entry 101548820         CDS       T07854                                  Symbol NOS2 Name (RefSeq) nitric oxide synthase, inducible   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism sara  Sorex araneus (European shrew) Pathway sara00220   Arginine biosynthesis sara00330   Arginine and proline metabolism sara01100   Metabolic pathways sara04020   Calcium signaling pathway sara04066   HIF-1 signaling pathway sara04146   Peroxisome sara04371   Apelin signaling pathway sara04926   Relaxin signaling pathway sara05010   Alzheimer disease sara05014   Amyotrophic lateral sclerosis sara05022   Pathways of neurodegeneration - multiple diseases sara05133   Pertussis sara05140   Leishmaniasis sara05142   Chagas disease sara05145   Toxoplasmosis sara05146   Amoebiasis sara05152   Tuberculosis sara05200   Pathways in cancer sara05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:sara00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     101548820 (NOS2)    00330 Arginine and proline metabolism     101548820 (NOS2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     101548820 (NOS2)    04066 HIF-1 signaling pathway     101548820 (NOS2)    04020 Calcium signaling pathway     101548820 (NOS2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     101548820 (NOS2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     101548820 (NOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101548820 (NOS2)   09162 Cancer: specific types    05222 Small cell lung cancer     101548820 (NOS2)   09171 Infectious disease: bacterial    05133 Pertussis     101548820 (NOS2)    05152 Tuberculosis     101548820 (NOS2)   09174 Infectious disease: parasitic    05146 Amoebiasis     101548820 (NOS2)    05145 Toxoplasmosis     101548820 (NOS2)    05140 Leishmaniasis     101548820 (NOS2)    05142 Chagas disease     101548820 (NOS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     101548820 (NOS2)    05014 Amyotrophic lateral sclerosis     101548820 (NOS2)    05022 Pathways of neurodegeneration - multiple diseases     101548820 (NOS2) Enzymes [BR:sara01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      101548820 (NOS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 Motif Other DBs NCBI-GeneID:  101548820 NCBI-ProteinID:  XP_012787376 LinkDB All DBs Position Unknown AA seq 1018 aa AA seqDB search MNPKSLIIGPKDKPTSPDELLPQAIEFINQYYNSFKEAKIEAHLARVEAITKEIEITGTY QLTGDELIYATKQAWRNAPRCIGRIQWANLQVFDARSCSTAQEMFEHICRHIRYATNNGN IRSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGTIRGDPACVEFTQLCIDLGWKPKY GRFDVVPLVLQADGRDPELFEIPPDLVLEVPMEHPKYEWFQELELKWYALPAVANMLLEV GGLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDRAVIEIN VAVLHSFQKQNVTIMDHHSAAESFMKYMQSEYRSRGGCPADWIWLVPPISGSITPVFHQE MISYVLSPFYYYQVEAWKTHIWADGKRRPHRREIHFRVLARAVLFASVLMHKSMATRVRV TILFATETGRSETLARDLGALFSCAFNPQVLCMDEYQLDRLEEEQLLLVLTSTFGNGDAP SNGQKLKKSLFMLKRLTNKFRYAVFGLGSSMYPQFCAFAHDLDQKLSLLGASQLSPTGEG DELSGQEEAFRSWAVQTFKAACESFQVRGKEHIEIPKRYSCNVDWEPQRHRLVQDSQPWD LSKALSSMHAKNVVTTRLKSLQPLQGPKSSRSVLLVELSCKDCPGLSYLPGDHLGVFPCN QPELVQGILERLADSPDPHQPVSLEILDEKGSYWVRDRRLPPCSLTQALTCFLDITTPPS QQLLQKLSLLAVAQEERQRLEELSQPSEYSKWKLAHSPTFLEVLGEFPSVRVPASFVLSQ LPLLKARYYSISSAAARVPCELHLTVAVLTYRTRAGQGPLHHGVCSTWLSSLKAGDPVPC FLQSANNFQLPQDPSQPCILVGPGTGIAPFRSFWQQRLYEAEHTGLQGGRLTLVFGCRHP DEDHLYREEILEMARKGVLHEVHTAYSRLPGQPKVYVQDILRQQLAGKVLRVLLEERGHI YVCGDVRMARAVGLTLRQLVAGALGLSEEQVEDYFFQLKWQGISSQETDKRHKAGDRG NT seq 3057 nt NT seq  +upstreamnt  +downstreamnt atgaacccaaagagtttgatcattggacccaaggataagcctacctcccccgatgagctt ctacctcaagcgatcgaatttatcaaccagtattacaactccttcaaagaggcaaaaata gaggcgcatctggcccgagtggaagcgataacaaaggagatagaaataacaggaacctac cagctgacgggggatgagctcatctacgccaccaagcaggcctggcgcaacgccccccgc tgcatcgggaggatccagtgggccaacctccaggtctttgatgctcggagctgttctact gcccaggaaatgttcgagcacatctgcagacacatccgttacgccaccaacaacggcaac atcaggtcggccatcacagtgttcccacagcggagcgacgggaagcacgacttcagggtg tggaacgcgcagctcatccgatacgccggctaccagatgccggacggcacgatccgcggg gaccccgcctgtgtggaattcacccagctgtgcatcgacctggggtggaagcccaagtac gggcgcttcgacgtggtgccgctggtcctgcaagccgatggccgcgacccggagctcttc gaaatcccgcctgacctggtgctcgaggtgcccatggagcatccgaagtatgagtggttc caggagctggagctgaagtggtacgccctgcctgcagtggccaatatgctgctggaagtg ggtggccttgagttcccagggtgtcccttcaacggctggtacatgggcacagagatcggg gtccgggacttctgtgatgtccagcgctacaacatcctggaggaagtgggccggaggatg ggcctggagacacacaagctggcctccctctggaaagaccgggctgtgattgagattaac gtcgccgtgctccatagtttccagaagcagaatgtcaccatcatggaccaccactcggcc gctgagtccttcatgaagtacatgcagagcgagtaccggtcccgtgggggctgtccagcc gactggatttggctggttcccccaatttctggaagcatcacccccgtgttccaccaggag atgataagctatgtcttgtcccctttctactactaccaggtggaggcctggaaaacccac atctgggcagatggtaaacggaggccccatagaagagagattcacttcagagtcttggct agggctgtgctctttgcctctgtcctcatgcacaagtccatggcaacccgggtcagagtc acaatcctctttgcgacagagacagggcgatcggaaacgctggcccgggacctgggggcc ttgttcagctgcgccttcaacccccaggttctctgcatggatgagtaccagctggacagg ctggaggaggagcagctgctgctggtgttgacaagcacatttggaaacggagatgccccc agcaatgggcagaaactgaagaaatccctcttcatgctgaaaaggctgactaacaagttc aggtacgccgtgtttggcctcggctccagcatgtaccctcagttctgcgcctttgctcac gacctggaccagaagctgtctctcctgggagcatctcagctcagccccaccggggagggg gacgagctcagcgggcaggaggaggccttccgaagctgggccgtgcaaaccttcaaggct gcctgtgagagcttccaagtcagaggcaaggaacacattgagatccccaagcgctacagt tgcaacgtggactgggaaccacagcgccacaggctggtgcaggactcacagccttgggac ctcagcaaagccctgagcagcatgcacgccaagaacgtggtgaccacgaggctcaaatcc ctgcagcctctccagggcccgaaatccagccgctctgtcctcctagtagaactttcctgc aaggactgccctggcctgagctacctgcccggagaccaccttggggttttcccatgcaac cagccggagctggtccagggcatcttggaacggctggcagacagccctgacccccaccaa cccgtgagcctggagatcctcgacgagaaaggcagctactgggtcagagaccggcggctg cccccctgctccctcacccaggccctcacctgcttcctggacatcaccacgccccccagc cagcagctgctccagaagctgtccctgctcgctgtggcccaggaggagaggcagcggctg gaggagctgagccagccctcagagtacagcaagtggaagctcgcccacagccccacgttc ctggaggtgctgggggagttcccgtccgtgcgggtgcccgccagctttgtgctctcgcag ctcccgctgctgaaagcccgctactactccatcagctccgccgccgcgcgcgtgccctgc gagctccacctgaccgtggcagtgctcacataccgcacccgagcaggccagggtcctctg catcatggtgtctgcagcacgtggctcagcagcctgaaggccggagacccagtgccctgc ttcctgcaaagtgccaacaacttccagctgcctcaagacccctctcaaccttgcatcctt gtcgggcctggcacgggcatcgccccctttcgcagtttctggcagcagcggctctatgaa gctgaacacacagggctccagggtggccgcctgaccctggtgtttgggtgccgccaccca gacgaggaccacctctatcgggaagagatactagagatggcccggaagggggtgctccat gaggtgcacacagcctactctcgcctgcctggccagcccaaggtctatgtgcaggacatc ctgcgacagcagctggcgggcaaggtgctccgcgtgctacttgaggagcgaggacacatc tacgtctgcggggatgtgcgcatggcgcgcgccgtgggcctcaccttgaggcagctggtg gccggcgcgctgggcctgagtgaggagcaggtggaggactatttcttccaactcaagtgg caggggatcagcagtcaagaaacagacaaaagacataaggctggggatagaggatga

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