Sorex araneus (European shrew): 101550098
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Entry
101550098 CDS
T07854
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
sara
Sorex araneus (European shrew)
Pathway
sara04217
Necroptosis
sara04380
Osteoclast differentiation
sara04620
Toll-like receptor signaling pathway
sara04621
NOD-like receptor signaling pathway
sara04630
JAK-STAT signaling pathway
sara04658
Th1 and Th2 cell differentiation
sara04659
Th17 cell differentiation
sara05145
Toxoplasmosis
sara05160
Hepatitis C
sara05161
Hepatitis B
sara05162
Measles
sara05164
Influenza A
sara05165
Human papillomavirus infection
sara05167
Kaposi sarcoma-associated herpesvirus infection
sara05168
Herpes simplex virus 1 infection
sara05169
Epstein-Barr virus infection
sara05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
sara00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
101550098 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
101550098 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
101550098 (TYK2)
04621 NOD-like receptor signaling pathway
101550098 (TYK2)
04658 Th1 and Th2 cell differentiation
101550098 (TYK2)
04659 Th17 cell differentiation
101550098 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
101550098 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
101550098 (TYK2)
05160 Hepatitis C
101550098 (TYK2)
05171 Coronavirus disease - COVID-19
101550098 (TYK2)
05164 Influenza A
101550098 (TYK2)
05162 Measles
101550098 (TYK2)
05168 Herpes simplex virus 1 infection
101550098 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
101550098 (TYK2)
05169 Epstein-Barr virus infection
101550098 (TYK2)
05165 Human papillomavirus infection
101550098 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101550098 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
sara01001
]
101550098 (TYK2)
Enzymes [BR:
sara01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101550098 (TYK2)
Protein kinases [BR:
sara01001
]
Non-receptor tyrosine kinases
JAK family [OT]
101550098 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
FERM_F1
SH2_1
Kdo
Kinase-like
ABC1
FERM_C_FAK1
DBD_Tnp_Mut
RIO1
Motif
Other DBs
NCBI-GeneID:
101550098
NCBI-ProteinID:
XP_004616827
LinkDB
All DBs
Position
Unknown
AA seq
1164 aa
AA seq
DB search
MPVCPWGANGRGRRPNGDGVQPEASRDGLKVLLHWAGPDGGDPWATFNDSTLTAEEICIQ
VAQKLGITPPCISLFALFDAQAHVWLPPNHILEVSRATPRTLHFRMRFYFRNWHGLNPQE
PSVFRCGPPGSAASSAEAQQGLPLLDAASFEYLFEQGKHEFVNDVVSLGELSTEEEIHHF
KNESLGMASLHLCQLALRRGVPLEEVARKISFKECIPRSFRRQIRQHNALTRLRLRTIFH
RFLRTFQPSRLSPHLVMVKYLATLERMAPRFGAERVPVCHLLLQAQATPPDPEPQSDPGS
MTHEVQVSGTLGLQWRPVATAGPSDGGGSADSDGEPQADPSEKKDKAQGVDRPRETPWVY
FCDFQDVTHVVLKDQNISIHCQDKCLELTLPSRPAALSLVALVDGYFRLTSDSSHYLCHE
VAPPRLVMSIQEGVHGPLLDPFVLAKLQSEDGLYLIHWSCHHYNRLILTVAQRDQASDGG
ARNWKLRKFPIQLQPGAFALEGWGRTFPSVGEMRAALQSCALRAGADSFMLRRCCRPGPG
EISNLIVLRGSQTSPQPLNLSQLSFHQISQDSITRLSHLGQGTRTNVYEGVLHVARGDQE
EDDKSDGEGCEQKLRVVLKVLDPGHQNISLAFYETASLMSQVSHMHLAFLHGVCVHGSES
TIVTEYVEHGPLDVWLRRERGRVPVAWKVTVTQQLASALSYLEDKSLAHGNVCGRNILLA
RPGLAEGSSPFIKLSDPGVGLGALSREERVERIPWTAPECLSGGAGGLSTAADKWGFGAT
VLEICFDGEVLLQGRSPSEKERFYQKQHRLPEPSCPELATLINQCLNYEPSQRPSFRTIL
RDLTQLQPQNLVNVLTVNPESPAADPTIFHKRYLKKIRDLGEGHFGKVTLYCYDPINDGT
GEMVAVKALKAGCGPQLRNGWRREIDILRTLYHEHIVKYKGCCEDQGEKSVQLVMEYVPQ
GSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHSQHYVHRDLAARNVLLDNERLVKIGDFG
LAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWSFGVTLYELLTHCDSRQS
PPLKFIELMGLTQGQMTVLRLTELLELGQRLPRPEKCPYEIYQLMKNCWETGASFRPTFQ
NLIPILKAAQEKYEAQAPSVFSVP
NT seq
3495 nt
NT seq
+upstream
nt +downstream
nt
atgcccgtgtgcccctggggtgccaatggcaggggccgccggcccaatggggatggggtg
cagcctgaggccagcagagatggcttgaaggtgcttctgcactgggctggccccgatggt
ggggacccctgggccaccttcaacgacagcaccctgaccgcggaggagatctgcatccag
gtcgcccagaaactcggcatcactcctccttgcatcagcctcttcgcgctcttcgatgcc
caggcccatgtctggctgcccccgaaccacatcttggaggtctccagggctaccccgcgc
acgctgcacttccgcatgaggttttatttccggaactggcacggcctgaacccccaggag
ccctcggtgttccgctgcgggcccccgggcagtgcggcatcctcggcggaggcccagcag
ggtttgcctctcctggacgcggcctccttcgagtacctcttcgagcagggcaagcacgag
tttgtgaatgatgtggtgtctctgggggagctgtccacggaggaagagatccaccacttc
aagaatgagagtctgggcatggcctctctgcacctgtgtcagctagcactccgccggggg
gtccccctggaggaagtggccaggaagatcagcttcaaggagtgtatcccgcgctccttc
cgccggcagatccgccagcacaacgccctgacgcggctgcgcctgcggaccatcttccac
cgcttcctgcgcaccttccagcccagccgcctcagcccacacctggtcatggtcaagtac
ctggccacgctcgagcgcatggcgccccgcttcggcgctgagcgcgtgcccgtgtgccac
ctgctcctgcaggctcaggccacccctcccgaccccgaaccgcagtcggaccccggatcc
atgacccacgaggtgcaggtgtccggcacgctgggcctccagtggcggccagtggccaca
gcgggtcccagtgatggtggcggcagtgctgacagtgacggggagccccaagctgaccca
tctgagaagaaagataaggcccagggggtggacagaccccgcgagacgccctgggtctat
ttctgcgacttccaagatgtcacgcacgtggttctgaaagaccagaacatcagcatccac
tgtcaggacaagtgcctggagctgacactgccttcccggcccgccgccctgtccttggtg
gccctggtggatggctacttccgcctcacgtctgactcaagccactacctgtgccacgaa
gtggctcccccacggctggtgatgagcatccaggagggggtacacgggcccctgctggac
ccctttgtgttggcaaagctgcagtcagaagatggactttacctcatccactggagctgc
caccactacaaccgtctcattctcacggtggcccagagggaccaggcctctgacggcggt
gccagaaactggaagctacgcaaattccctatccagctgcagccaggggctttcgccctg
gaaggctggggccgcactttccccagcgtgggggagatgcgggccgccttgcagagctgc
gccctacgggccggcgccgattcctttatgctgcgccgctgctgccggccaggacccgga
gagatctccaacctcatcgtcctacggggctcccagaccagcccccagcctctcaacctc
agccagctcagcttccatcagatcagccaggattcgatcacccggctctcccacttgggc
cagggcaccaggaccaacgtgtatgagggtgtcttgcacgtggccagaggagaccaggag
gaggatgacaagagcgatggtgagggctgtgaacagaagctccgagtggtgctcaaggtg
ctggaccctggccaccagaacatctccctggccttctacgagaccgccagtctcatgagc
caggtgtcccacatgcacctggcctttctgcacggcgtctgcgttcacggctccgagagc
accatagtgactgagtacgtggaacatgggcccctggacgtgtggctgcggcgggagagg
ggtcgtgtgcccgtggcctggaaagtgaccgtgacccagcagctagccagtgccctcagc
tacttggaagataagagcctcgcccacgggaatgtgtgtggccggaacattctgctggca
cggccggggctggcggaaggcagcagccccttcattaagctgagtgaccccggcgtgggc
ctgggagccctctcccgagaggagcgggtggagcgcatcccctggacagcccccgagtgc
ctgtctgggggcgccggcggcctcagcacagcggctgacaagtggggctttggggccact
gtccttgagatctgctttgacggggaggttctcctgcagggccgcagcccctcggagaaa
gagcgtttctaccagaagcagcatcgccttcccgagccctcatgccctgagctggccaca
ctcatcaaccagtgcctgaactacgagccatcccagcggccttccttccgcaccatcctc
cgggatcttacgcagctgcagccacaaaatcttgttaatgtcctcaccgtgaacccggaa
tcccctgccgccgaccccacgattttccacaaacgctacttgaaaaagattagggatctg
ggcgagggtcattttggtaaagtcaccctctactgctacgacccgatcaacgatggcact
ggcgagatggtggccgtgaaagccctcaaagcgggctgtggcccccagctccgcaacggc
tggcggcgggagattgacatcctgcgcacgctttaccatgagcatatagtcaaatacaag
ggctgctgtgaggaccaaggcgagaagtcagtacagctcgttatggagtacgtgccccag
ggcagcctccgggactacctgccgagacacagtgtcggactggcccagctactgctcttt
gcccagcagatctgcgagggcatggcctacctacattcgcagcactacgtgcaccgagac
ctggccgcgcgcaatgtgctgcttgacaacgagaggctggtcaagatcggggactttggc
ctagccaaggccgtgcccgaaggccacgagtactaccgcgtgcgcgaggatggggacagc
cccgtgttctggtacgcccccgaatgtctgaaggagtgtaagttctactatgcatctgac
gtctggtcctttggggtcaccttatatgagctgctgacacattgtgactccagacagagc
cccccattgaaattcatcgaactcatgggcctgacccagggccagatgactgtactgcga
ctcacagaactcctggaactgggccagcggctgccacggccggagaagtgtccttatgag
atctaccagctcatgaagaactgctgggagacgggagcgtcgttccgccctaccttccag
aacctcatccccatcctcaaggcggcccaggagaagtacgaggcccaggccccatctgtg
ttcagcgtcccctga
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integrated database retrieval system
