Sorex araneus (European shrew): 101551730 Help Entry 101551730         CDS       T07854                                  Symbol ADCY9 Name (RefSeq) adenylate cyclase type 9   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism sara  Sorex araneus (European shrew) Pathway sara00230   Purine metabolism sara01100   Metabolic pathways sara01522   Endocrine resistance sara04015   Rap1 signaling pathway sara04020   Calcium signaling pathway sara04022   cGMP-PKG signaling pathway sara04024   cAMP signaling pathway sara04062   Chemokine signaling pathway sara04072   Phospholipase D signaling pathway sara04081   Hormone signaling sara04082   Neuroactive ligand signaling sara04114   Oocyte meiosis sara04211   Longevity regulating pathway sara04213   Longevity regulating pathway - multiple species sara04261   Adrenergic signaling in cardiomyocytes sara04270   Vascular smooth muscle contraction sara04371   Apelin signaling pathway sara04540   Gap junction sara04611   Platelet activation sara04713   Circadian entrainment sara04714   Thermogenesis sara04723   Retrograde endocannabinoid signaling sara04724   Glutamatergic synapse sara04725   Cholinergic synapse sara04727   GABAergic synapse sara04750   Inflammatory mediator regulation of TRP channels sara04911   Insulin secretion sara04912   GnRH signaling pathway sara04913   Ovarian steroidogenesis sara04914   Progesterone-mediated oocyte maturation sara04915   Estrogen signaling pathway sara04916   Melanogenesis sara04918   Thyroid hormone synthesis sara04921   Oxytocin signaling pathway sara04923   Regulation of lipolysis in adipocytes sara04925   Aldosterone synthesis and secretion sara04926   Relaxin signaling pathway sara04927   Cortisol synthesis and secretion sara04928   Parathyroid hormone synthesis, secretion and action sara04934   Cushing syndrome sara04935   Growth hormone synthesis, secretion and action sara04961   Endocrine and other factor-regulated calcium reabsorption sara04962   Vasopressin-regulated water reabsorption sara04970   Salivary secretion sara04971   Gastric acid secretion sara04972   Pancreatic secretion sara04976   Bile secretion sara05032   Morphine addiction sara05163   Human cytomegalovirus infection sara05166   Human T-cell leukemia virus 1 infection sara05200   Pathways in cancer sara05207   Chemical carcinogenesis - receptor activation sara05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:sara00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     101551730 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     101551730 (ADCY9)    04371 Apelin signaling pathway     101551730 (ADCY9)    04020 Calcium signaling pathway     101551730 (ADCY9)    04072 Phospholipase D signaling pathway     101551730 (ADCY9)    04024 cAMP signaling pathway     101551730 (ADCY9)    04022 cGMP-PKG signaling pathway     101551730 (ADCY9)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     101551730 (ADCY9)    04081 Hormone signaling     101551730 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     101551730 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     101551730 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     101551730 (ADCY9)    04062 Chemokine signaling pathway     101551730 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     101551730 (ADCY9)    04923 Regulation of lipolysis in adipocytes     101551730 (ADCY9)    04912 GnRH signaling pathway     101551730 (ADCY9)    04913 Ovarian steroidogenesis     101551730 (ADCY9)    04915 Estrogen signaling pathway     101551730 (ADCY9)    04914 Progesterone-mediated oocyte maturation     101551730 (ADCY9)    04921 Oxytocin signaling pathway     101551730 (ADCY9)    04926 Relaxin signaling pathway     101551730 (ADCY9)    04935 Growth hormone synthesis, secretion and action     101551730 (ADCY9)    04918 Thyroid hormone synthesis     101551730 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     101551730 (ADCY9)    04916 Melanogenesis     101551730 (ADCY9)    04925 Aldosterone synthesis and secretion     101551730 (ADCY9)    04927 Cortisol synthesis and secretion     101551730 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     101551730 (ADCY9)    04270 Vascular smooth muscle contraction     101551730 (ADCY9)   09154 Digestive system    04970 Salivary secretion     101551730 (ADCY9)    04971 Gastric acid secretion     101551730 (ADCY9)    04972 Pancreatic secretion     101551730 (ADCY9)    04976 Bile secretion     101551730 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     101551730 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     101551730 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     101551730 (ADCY9)    04727 GABAergic synapse     101551730 (ADCY9)    04725 Cholinergic synapse     101551730 (ADCY9)    04723 Retrograde endocannabinoid signaling     101551730 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     101551730 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     101551730 (ADCY9)    04213 Longevity regulating pathway - multiple species     101551730 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     101551730 (ADCY9)    04714 Thermogenesis     101551730 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101551730 (ADCY9)    05207 Chemical carcinogenesis - receptor activation     101551730 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101551730 (ADCY9)    05163 Human cytomegalovirus infection     101551730 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     101551730 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     101551730 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     101551730 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     101551730 (ADCY9) Enzymes [BR:sara01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      101551730 (ADCY9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom Motif Other DBs NCBI-GeneID:  101551730 NCBI-ProteinID:  XP_004604427 LinkDB All DBs Position Unknown AA seq 1353 aa AA seqDB search MASPPHQQLLPHHSTEVSCDSSGDSNSVRVKINPKQLVSNSHAKHCKYSISSSCSSSGDS GAGPRRAGGGGRLRRQRKLPQLFERASSRWWDPRFDSVNLEEACLERCFPQTQRRFQCAL FYIGFACLLWSVYFAVHMRPKLTVMVAPALGFLAVCVGFFLFTFTKLYARHYVWTSLVLT LLVSALTLAAQFQVLRPDSGRVDSSNHTPAAKPTDTCLSQVGSFSMCIQVLFLLYTVMHL PLYLSVFLGAVYSVLFETFGYYFQNEACFPPPGSGAPHLELLSRALLHVCVHAIGIHLFV MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMRQGDEESENSIKR HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGKVTERLGQSVVADQLKGLKTYLIAGHRAKATHCSCSEAWLSGPEATDGSQVS SGPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFAPPLDTSTEGGAMQNGCQEEPRN GTKASGGANSKSQNGLLSPPPEERLTTSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNI REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLSFLDQELERAYRTSYQQEVIRNAPVRTF ASATFSSLLDVLLSTVVFLILSITCFLKHGAAASPPPPAALAVFGAALLLELLSLVVSVR MVFFPESVMACTKRLLEWIAGWLPRHCIGAILVSLPALAVYSHVTSEFETNIQLTVFTGS AVLIAVVHYCNFCQLSSWMRSALATAVGAVPLLALCLSLCPDSSIVISQLDAVQNFSAER SPCNSSLPHDSRRPTSLIGQEVILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTK IQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDNGAVIFASIVNFSEFYEENYEGGKE CYRVLNELIGDFDELLGRPDYSSIEKIKTIGATYMAASGLNATQAADGSHPQEQLRSLFE FARELMRVVGDFNSNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTT GVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLFPKCTDNGGVPQHQLSISP DIRVQVDGSIGRSPTDEIANLVPSVQSVEKTPLGPDDSAQAKDTQPTSKRLWKEPARAEE RARLSRALESSDCDDVGLEEANELTRLNVSPRV NT seq 4062 nt NT seq  +upstreamnt  +downstreamnt atggcctccccgccccaccagcagctgctgccgcaccacagcaccgaggtgagctgcgac tcgagcggggacagcaacagcgtcagggtcaagatcaaccccaagcagctggtgtccaac agccacgccaagcactgcaagtacagcatctcctccagctgcagcagctcgggggactcg ggcgcgggtccccgcagagcgggcggcgggggccgcctgcggcggcagaggaagctgccc cagctgttcgagagggcgtccagccgctggtgggacccccggttcgactcggtgaacctg gaggaggcttgcctggagcgctgcttcccgcagacccagcgccgtttccagtgcgcgctc ttctacatcggcttcgcctgcctgctctggagcgtctacttcgccgtgcacatgagaccc aagctcacggtcatggtcgcccctgccctgggcttcctcgccgtctgcgtgggcttcttc ctgtttaccttcaccaagctgtacgcccggcattacgtgtggacctcgctggttctcacc ctcctggtgtccgccctgaccctggctgcccagtttcaggttttgaggcctgactcagga cgtgttgacagctccaatcacactcccgcggccaagcccacggacacttgcttatctcaa gtggggagcttctccatgtgcatccaagtgctctttctgctctacaccgtcatgcactta cctttgtacctgagcgtgtttctgggagcggtctactccgttctgtttgagacctttggc tattatttccaaaatgaagcttgcttccccccacccggctcgggggccccacacttggag ctgctgagccgggccttgctccatgtctgtgtccatgccatcggcatccacctgttcgtc atgtcccaggtgaggtcccggagcacctttctcaaggtgggccagtccatcatgcacggg aaggacctggaggtggaaaaggccctcaaagagcggatgattcactcagtgatgccaaga atcatcgcagacgacttgatgaggcagggggatgaggagagtgagaattccatcaaaagg catgccacctcaagccccaagaacaggaagaagaagtcttccatccagaaggcccccata gccttccgcccattcaagatgcagcagattgaagaagtcagcattttgtttgcagatatc gtgggcttcaccaaaatgagtgccaacaagtctgcccatgcgctggtgggcctcctgaat gatctgtttggccgtttcgaccgcttgtgtgaagagaccaagtgcgagaagatcagcacc ctgggagactgctactactgcgtggcggggtgtcctgagccccgagccgaccatgcttac tgctgcatcgagatgggtctgggcatgatcagagccattgagcagttctgccaggagaag aaagagatggtaaacatgcgtgtcggggtgcacacaggcactgttctgtgtggcatcttg ggcatgaggaggtttaagttcgatgtgtggtccaacgatgtgaacctggccaatctcatg gagcagctgggagtggctggcaaggtgcacatttctgaggccactgcaaaatacctagat gaccggtacgagatggaagatggaaaggtcaccgagcgcctcggccagagcgtcgttgcc gaccagttgaaaggtttgaagacatacctgatagcgggtcacagagcgaaggcgactcat tgcagctgctcagaggcctggctttctggccctgaggccactgacggctcacaggtgtcc tcaggccctaggggacaggggacagcgtcgccagggagtgtcagtgacttggcacagact gtcaaaacctttgataaccttaagacctgcccttcatgtggaatcacgtttgcacccccg ttggacaccagcacagagggaggagcgatgcagaacggctgtcaggaggagcccaggaat ggcaccaaggcttccggaggggccaattccaagtcgcagaatggactgctcagcccgccc ccggaggagcgactcaccaccagccagacgtccctgtgtgagatcctccaggagaaaggg cgctgggcgggcgtgagcctggaccagtcggcgctgctgccgctgaggttcaagaacatc cgcgagaagacggatgcccacttcgtggacgtcatcaaggaagacagcctgatgaaagat tactttttcaagccgcccatcaatcagttcagcctgagtttcctggaccaggagctggag cgcgcctacaggaccagctaccagcaggaggtgatcagaaatgctcccgtgaggaccttt gccagcgccaccttcagctccctgctggacgtgctcctgtccacggtggtgttcctgatt ctctccatcacctgcttcctgaagcatggggccgccgcctcgcccccgccacctgccgcc ctggccgtgtttggggcagcgctgctgctggagctgctgtccctcgtggtctctgtcagg atggtgttcttccccgagagcgtcatggcctgcaccaagcgcctgctggagtggatcgcg ggctggcttcctcgccactgcatcggggccatcctggtgtcactccccgccctggctgtc tactcacatgtcacctcagagtttgagacaaacatacagctcaccgtgttcacgggctcg gccgtcctgattgctgtagtgcattattgcaacttctgccagctcagctcctggatgagg tcggccctggccactgcagtcggggctgtgcccctgctcgcactctgcctctccctgtgc ccagacagttctatagtcatttcgcagcttgatgcagttcagaatttcagcgcggagcgg agcccctgtaatagctccctgccacatgacagccggcggccgaccagcctcattggccag gaggtgatcctggtcttcttcctcctgctgctgctcgtctggttcctgaaccgggagttc gaggtcagctaccgcctccactaccacggggacgtggaggccgacctccaccgcaccaag atccagagcatgcgcgaccaggccgactggctgctgcggaacatcatcccctaccacgtg gccgagcagctcaaggtctcccagacctactccaagaaccacgacaatggcgccgtcatc ttcgccagcatcgtcaacttcagcgagttctacgaggagaactacgaaggcggcaaggag tgctaccgcgtgctcaacgagctcatcggcgacttcgacgagctcctgggccggcccgat tacagcagcatcgagaagatcaagaccattggggccacatacatggcggcgtcggggctg aacgccacgcaggcggcggacggcagccacccgcaggagcagctgcgcagcctcttcgag ttcgccagggagctgatgcgggtggtaggcgacttcaacagcaacatgctctggttcaac ttcaagctcagggtgggcttcaaccacgggcccctcacggcgggcgtcatcggcaccacg aagctgctgtacgacatctggggggacacggtgaacatagccagcaggatggacacgact ggcgtggagtgccgcatccaggtgagcgaggagagctaccgggtcctgagcaagatgggc tatgacttcgactacagaggcacggtgaacgtgaaggggaagggccagatgaagacctac ctcttccccaagtgcacggacaacgggggcgtgccgcagcaccagctgtccatctccccg gacatccgggtccaggtggacggcagcatcggacggtctcccacggacgagattgccaac ctggtgccttccgtccagagcgtggaaaagacaccgctgggtcccgacgacagcgcgcag gccaaggacactcagcccacgtctaagagactctggaaggagccggccagggccgaggag cgggcccggctcagcagggccctggagagcagcgactgtgacgacgtggggctggaggag gccaacgagctcacccggctcaacgtctccccccgcgtgtga

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