Sorex araneus (European shrew): 101552331
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Entry
101552331 CDS
T07854
Symbol
MET
Name
(RefSeq) hepatocyte growth factor receptor isoform X1
KO
K05099
proto-oncogene tyrosine-protein kinase Met [EC:
2.7.10.1
]
Organism
sara
Sorex araneus (European shrew)
Pathway
sara01521
EGFR tyrosine kinase inhibitor resistance
sara04010
MAPK signaling pathway
sara04014
Ras signaling pathway
sara04015
Rap1 signaling pathway
sara04020
Calcium signaling pathway
sara04151
PI3K-Akt signaling pathway
sara04360
Axon guidance
sara04510
Focal adhesion
sara04520
Adherens junction
sara05100
Bacterial invasion of epithelial cells
sara05144
Malaria
sara05200
Pathways in cancer
sara05202
Transcriptional misregulation in cancer
sara05205
Proteoglycans in cancer
sara05206
MicroRNAs in cancer
sara05208
Chemical carcinogenesis - reactive oxygen species
sara05211
Renal cell carcinoma
sara05218
Melanoma
sara05223
Non-small cell lung cancer
sara05225
Hepatocellular carcinoma
sara05226
Gastric cancer
sara05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
sara00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101552331 (MET)
04014 Ras signaling pathway
101552331 (MET)
04015 Rap1 signaling pathway
101552331 (MET)
04020 Calcium signaling pathway
101552331 (MET)
04151 PI3K-Akt signaling pathway
101552331 (MET)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101552331 (MET)
04520 Adherens junction
101552331 (MET)
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
101552331 (MET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101552331 (MET)
05202 Transcriptional misregulation in cancer
101552331 (MET)
05206 MicroRNAs in cancer
101552331 (MET)
05205 Proteoglycans in cancer
101552331 (MET)
05208 Chemical carcinogenesis - reactive oxygen species
101552331 (MET)
05230 Central carbon metabolism in cancer
101552331 (MET)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
101552331 (MET)
05226 Gastric cancer
101552331 (MET)
05218 Melanoma
101552331 (MET)
05211 Renal cell carcinoma
101552331 (MET)
05223 Non-small cell lung cancer
101552331 (MET)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
101552331 (MET)
09174 Infectious disease: parasitic
05144 Malaria
101552331 (MET)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101552331 (MET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
sara01001
]
101552331 (MET)
Enzymes [BR:
sara01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101552331 (MET)
Protein kinases [BR:
sara01001
]
Receptor tyrosine kinases (RTK)
MET family
101552331 (MET)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
TIG
Pkinase
Sema
PSI
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
101552331
NCBI-ProteinID:
XP_004602131
LinkDB
All DBs
Position
Unknown
AA seq
1382 aa
AA seq
DB search
MKAPAVLAPGVLVLLFTLVQRSEGECREALVKSEMNVNMKYQLPNFTAETPIQHVVLHKH
HIYLGAVNSLYVLNDKDLQKVAEYKTGPVLEHPDCLPCQDCHHKANSSGGIWKDNVNMAL
LVDTYYDDQLISCGSVHRGTCQRHVLPPDNTADIHSEVHCMYSSQADEEPNQCPDCVVSA
LGTKVLLSEKERFINFFVGNTINSSYPPNHSLHSISVRRLKETQDGFKFLTDQSYIDVLP
EFRDSYPVKYIHAFESNHFIYFLTVQRETLDAQTFHTRIIRFCSTDSGLHSYMEMPLECI
LTEKRRKRATREEVFNILQAAYVSKPGAHLAKQIGANPNDDILYGVFAQSKPDSAEPMNR
SAVCAFPIKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARSDEYRTE
FTTALQRVDLFMGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGSSTPHVNF
LLDSHPVSPEVIVEHSSEQDGYTLVVTGKKITKIPLNGLGCEHFQSCSQCLSAPAFVQCG
WCQDKCVQVEGCPSGTWTQETCLPTIYKVFPTSAPLEGGTTLTVCGWDFGFRRNNKFDLK
KTKVLLGNESCTLTLSESTTNMLKCTVGPSINEHFNMSLTVSNGREAAQYSTFSYVDPII
TSISPSYGPQTGSTLLTLTGKYLNSGNSRHISIGGKTCTLKSVSDSTLECYTPAQTTSTE
FPVKLKIDLANRETDSFSYRDDPIVYEIHPTKSFISGGSTITGVGKNLDSVSVLRMVITV
HEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLTTKAFFMLDGIHSKYFDLIYVHNP
VFKPFEKPVKISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHSYSETVLCTVPND
LLKLNSELNIEWKQAVSSTILGKVVVQPDQNLTGMIVGIVLISVMLLLLLGLFLWWKKRK
QIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNG
SCRQVQYPLTDLSPILTSGDSDISSPLLQNSVHIDLSALNPELVQAVQHVVIGPSSLIVH
FNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHANV
LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHSPTVKDLIGFGLQVAKGMKYLASKK
FVHRDLAARNCMLDENFTVKVADFGLARDIYDKEYYSVHNKTGAKLPVKWMALESLQTQK
FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITIYLLQGRRLLQPEYCPDPLYEVMLKC
WHPKAELRPSFSELVSRISGIFSTFIGEHYVHVNTTYVNVKCVAPYPSLLSSQGNVEGQG
DT
NT seq
4149 nt
NT seq
+upstream
nt +downstream
nt
atgaaagcccctgctgtgcttgcacctggcgtccttgtgcttctgtttaccttggtgcag
aggagtgaaggggaatgcagagaagcgctggtgaagtcggagatgaatgtgaacatgaag
tatcagcttcccaacttcactgccgagacgcccatccagcatgtggttctgcataagcat
catatttacctcggggctgtgaactccctttatgttttaaacgacaaagacctgcagaag
gttgccgaatacaaaacaggcccggtgctggaacacccagactgcttgccctgccaggac
tgccaccacaaagccaattcatcaggtggcatttggaaagataacgtcaacatggcactg
cttgttgacacatactacgatgaccagctcattagctgtggcagcgtccacagagggacc
tgccagcgacacgtgctgcccccggacaatactgctgacatccactcggaggttcactgc
atgtactcctcacaggcggacgaagagccgaaccagtgtcccgactgcgtggtgagcgcc
ctgggaaccaaagtcctgctgtcggagaaggagcgtttcatcaacttctttgtgggcaac
actatcaactcttcttatcctcccaatcattccttgcattctatctccgtgagacggctg
aaggaaacgcaagatggtttcaagttcttgacagaccagtcctatattgatgtcctgcct
gagttccgagactcttaccccgttaagtacatccatgccttcgagagcaaccatttcatt
tacttcctgacagtccagcgggaaacgctggatgctcagactttccacacgagaataatc
aggttctgttccacagactccgggttgcattcttacatggagatgcctctggagtgtatt
ctcacagagaagagaagaaagagggccacaagggaggaagtgttcaatattctccaagct
gcgtatgtcagtaaacccggggcccatctcgctaagcaaataggtgccaacccgaatgat
gacattctctacggggtgtttgcccagagcaagccggattctgccgagccgatgaaccgc
tctgcagtctgtgcattccctatcaagtatgtcaatgaattcttcaacaagattgtcaac
aaaaacaatgtgaggtgtctccagcacttctatggacccaaccacgagcactgctttaac
agaacgcttttaagaaattcatcgggctgtgaagcacgcagtgatgaatatcggacagag
tttaccacggctttgcagcgagttgacttattcatgggccagttcaaccaagtcctccta
acctctatatccaccttcattaaaggagatctcaccatcgcaaatcttggcacttcagag
ggtcgcttcatgcaggttgtggtttcccgatcgggatcatcaactcctcatgtgaatttc
ctcctggattcccaccctgtgtctccagaagtgattgtagaacactcctcggaacaagat
ggttacacattagttgtcacggggaagaagatcaccaagatcccgctgaacggcctgggc
tgtgagcattttcagtcctgcagtcagtgtctctctgcccctgcctttgtgcagtgtggc
tggtgccaggataaatgtgtgcaagtggagggatgccccagtggaacgtggactcaagag
acctgtctgccgacaatctacaaggttttcccaaccagtgcacctcttgaaggaggaaca
acattgacagtatgtggctgggactttggattccggaggaataataaatttgatctaaag
aaaaccaaggttctccttggaaatgagagctgcacgttaaccttgagtgagagcacaaca
aatatgttaaaatgcacagttggtccttcaatcaatgaacattttaatatgtcactaact
gtttcaaatggtcgagaggctgcacaatatagtacattttcttatgttgatcccataata
acaagtatttctccaagttatggccctcagactggcagtactttacttactttaactgga
aaatacctcaacagtggaaattctagacacatttcaattggtggaaagacgtgtacctta
aaaagtgtgtcagatagcactctcgagtgttataccccagcccaaaccacttcaactgag
tttccagttaaactgaaaattgacttagccaaccgagagacggacagcttcagttaccgg
gatgaccccattgtctatgaaattcacccaaccaaatcttttatcagtggtgggagcaca
ataacaggtgttggaaaaaatctggattcggtgagtgtcctgaggatggtgataaccgta
cacgaagcaggaaggaactttacagtggcatgtcaacatcgctctaattcagagataatc
tgctgtaccactccttcattgcaacagctgaatctgcagctccccctgacaaccaaggcc
tttttcatgttagatgggatccattccaaatactttgatctcatttatgtacataatccc
gtgtttaagccttttgaaaagccagtgaagatctcaataggcaatgaaaatgtactggaa
attaaggggaatgatattgaccctgaagcagttaaaggtgaagtgctaaaagtcggaaat
aagagctgtgagaatattcactcatattctgaaaccgttttatgtacagtccccaatgac
ctgttgaaattgaacagtgagttaaatatagagtggaagcaagcagtttcttcaactatt
cttggaaaagttgtagttcaaccagatcagaatctcacgggaatgattgttggtattgtt
ttaatatcagtaatgctcttactactacttggccttttcctgtggtggaaaaagagaaag
caaattaaagatctgggcagtgaattagttcgctatgatgcaagagtacacactcctcat
ttggataggcttgtaagtgcccgaagtgtaagcccaactacagaaatggtttcaaatgaa
tctgtagactacagagctacttttccagaagaccagtttcctaactcatctcagaacgga
tcttgcagacaagttcagtatcctctgacggacctatcccccatcctcactagtggggat
tctgatatatccagtccattactgcaaaatagtgtccacattgacctcagtgctctaaat
ccagagctggtccaggcagtgcagcacgtagtaattgggcccagcagcttgattgtgcat
ttcaatgaagtcataggaagaggacattttgggtgtgtgtatcatggaaccttgctggac
aatgatgacaagaaaatccattgtgctgtgaagtccttgaatagaatcactgacatagaa
gaagtgtctcagtttctgactgagggcatcattatgaaagatttcagccatgccaatgtt
ctctcactgttgggaatctgcctgcgaagtgaggggtctccactggtggttctaccatat
atgaaacatggagatcttcgaaatttcattagaaatgagactcatagtccaactgtaaaa
gatctcattggctttggtcttcaagtagccaaaggcatgaaatatcttgcaagcaaaaag
tttgtccacagagacttggctgcaagaaactgtatgttggatgagaatttcactgttaag
gttgctgattttggtcttgccagagatatatatgataaggaatactatagtgtccacaac
aaaacaggagcgaaactgccagtgaagtggatggctttagaaagtctacaaactcagaag
ttcaccaccaagtcagatgtgtggtcctttggtgtgctcctctgggagctgatgacaaga
ggggcaccgccttatccagacgtcaatacatttgacatcacaatctacttgttgcaaggc
aggaggctcttacaacctgaatactgcccagatcccttgtatgaagtgatgttaaaatgc
tggcaccctaaagctgaactgcgcccatccttctctgaactggtctccaggatatcgggg
atattctccactttcatcggggaacattatgtccatgtgaacactacttatgtgaatgtc
aagtgtgtcgctccctatccttctcttttgtcctcacaaggtaatgttgaaggccagggg
gacacatga
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integrated database retrieval system