Sorex araneus (European shrew): 101553495 Help Entry 101553495         CDS       T07854                                  Symbol TGFBR2 Name (RefSeq) TGF-beta receptor type-2   KO K04388   TGF-beta receptor type-2 [EC:2.7.11.30] Organism sara  Sorex araneus (European shrew) Pathway sara04010   MAPK signaling pathway sara04060   Cytokine-cytokine receptor interaction sara04068   FoxO signaling pathway sara04144   Endocytosis sara04218   Cellular senescence sara04350   TGF-beta signaling pathway sara04380   Osteoclast differentiation sara04390   Hippo signaling pathway sara04520   Adherens junction sara04659   Th17 cell differentiation sara04926   Relaxin signaling pathway sara04933   AGE-RAGE signaling pathway in diabetic complications sara05142   Chagas disease sara05161   Hepatitis B sara05166   Human T-cell leukemia virus 1 infection sara05200   Pathways in cancer sara05202   Transcriptional misregulation in cancer sara05210   Colorectal cancer sara05212   Pancreatic cancer sara05220   Chronic myeloid leukemia sara05225   Hepatocellular carcinoma sara05226   Gastric cancer sara05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:sara00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101553495 (TGFBR2)    04350 TGF-beta signaling pathway     101553495 (TGFBR2)    04390 Hippo signaling pathway     101553495 (TGFBR2)    04068 FoxO signaling pathway     101553495 (TGFBR2)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101553495 (TGFBR2)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     101553495 (TGFBR2)   09143 Cell growth and death    04218 Cellular senescence     101553495 (TGFBR2)   09144 Cellular community - eukaryotes    04520 Adherens junction     101553495 (TGFBR2)  09150 Organismal Systems   09151 Immune system    04659 Th17 cell differentiation     101553495 (TGFBR2)   09152 Endocrine system    04926 Relaxin signaling pathway     101553495 (TGFBR2)   09158 Development and regeneration    04380 Osteoclast differentiation     101553495 (TGFBR2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101553495 (TGFBR2)    05202 Transcriptional misregulation in cancer     101553495 (TGFBR2)   09162 Cancer: specific types    05210 Colorectal cancer     101553495 (TGFBR2)    05212 Pancreatic cancer     101553495 (TGFBR2)    05225 Hepatocellular carcinoma     101553495 (TGFBR2)    05226 Gastric cancer     101553495 (TGFBR2)    05220 Chronic myeloid leukemia     101553495 (TGFBR2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101553495 (TGFBR2)    05161 Hepatitis B     101553495 (TGFBR2)   09174 Infectious disease: parasitic    05142 Chagas disease     101553495 (TGFBR2)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     101553495 (TGFBR2)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     101553495 (TGFBR2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:sara01001]     101553495 (TGFBR2) Enzymes [BR:sara01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.30  receptor protein serine/threonine kinase      101553495 (TGFBR2) Protein kinases [BR:sara01001]  Receptor serine/threonine kinases (RSTK): TKL group   TGFBR2 family [OT]    101553495 (TGFBR2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  ecTbetaR2 PK_Tyr_Ser-Thr Pkinase ABC1 Haspin_kinase Motif Other DBs NCBI-GeneID:  101553495 NCBI-ProteinID:  XP_004603903 LinkDB All DBs Position Unknown AA seq 567 aa AA seqDB search MGRGLLRGLWPLHLVLWMRIASTISPHVQKSVNNDMMATDSNSAMKFSQLCKFCDVRSST CDNQKSCMSNCSITAICENAQEVCVAVWRKNDENITLETVCHDPKLTYHGFVLDDADSPK CIMKEKKRSGETFFMCSCSSEECNDYIIFSEEIDSNNPDLWLVIFQVTGVSLLPPLGIAI AVIVTFYCYRVHRQQKLSPSWETSKPRKRMEFSEHLAIILEDDRSDISSTCANNINHNTE LLPIELDMLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLK HENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAH LHSDHTLCGTPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVG TARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVRE HPCVESMKDNVLRDRGRPEIPSSWLSHQGIQMVCETLTECWDHDPEARLTAQCVAERFSE LEHLDRLSGRSCSEEKIPEDGSLNTTK NT seq 1704 nt NT seq  +upstreamnt  +downstreamnt atgggtcgggggctgctccggggcctgtggccgctgcacctcgtcctgtggatgcgcatc gccagcacgatctcaccgcacgttcagaagtcggttaacaatgacatgatggctacggac agcaatagtgcaatgaagttttcacagttgtgtaaattctgtgatgtgagatcatcgacg tgtgacaaccagaaatcttgcatgagcaactgcagcattacggccatctgcgagaacgca caagaagtctgtgtggctgtctggagaaaaaatgatgaaaacataaccctcgagacggtt tgccatgaccccaagctcacctatcatggatttgttcttgacgatgcggattctccaaag tgtataatgaaggagaaaaagaggtctggtgagactttcttcatgtgttcctgtagctct gaagagtgcaacgactatatcatcttctcggaagaaatcgacagcaacaaccccgacttg tggttagtcatattccaagtgacaggtgtcagcctcctgccacccctggggattgccatt gctgtcattgtcaccttctactgctaccgtgtacaccggcagcagaaactgagtccctca tgggagaccagcaaaccaaggaagcgcatggagttcagcgaacacctggccatcatcctg gaggatgaccgctcagacatcagctccacgtgcgccaacaacatcaaccacaacaccgag ctgctgcccatcgaactggacatgctggtgggcaaaggccgctttgctgaggtctacaag gccaagctgaaacagaacacttccgagcagtttgagaccgtggcggttaaaatcttccct tacgaggaatatgcctcctggaagacagagaaagacattttctccgacatcaacctcaaa catgagaacattctccagttcctgacggctgaggagcgcaagactgaattggggaagcag tattggctgatcacggctttccatgccaagggcaacttgcaggagtacctcaccaggcat gtcatcagctgggaggacctgcgaaagttgggcagctccctggcccggggcattgctcac ctgcatagtgatcacaccctgtgtgggacacccaagatgcccatcgtgcatagggacctc aagagctccaacattcttgtaaagaatgacctgacctgctgcctctgtgactttggtctt tccctgcgtctagacccaacgctgtctgtggatgacttggccaatagtggtcaggtggga actgcaagatacatggccccagaagttctagagtccaggatgaatttagagaacgttgag tcattcaagcagacggatgtctactccatggctctggtgctctgggaaatgacgtctcgg tgcaatgctgtgggagaagtgaaagattatgagccaccgtttggttccaaggtacgggag catccctgtgtggaaagcatgaaggacaatgtgctgagagatcgggggcgaccagaaatc cctagttcctggctcagtcaccagggcatccagatggtgtgtgagacgctgaccgagtgc tgggaccacgaccctgaagcccggctcacagcccagtgcgtggcagaacgcttcagtgag ctggagcacctggaccgactctcgggacggagctgctctgaggagaagattcctgaagac ggctctctgaacactaccaaatag

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