KEGG   Sorex araneus (European shrew): 101554044
Entry
101554044         CDS       T07854                                 
Symbol
MAPK11
Name
(RefSeq) mitogen-activated protein kinase 11
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
sara  Sorex araneus (European shrew)
Pathway
sara01522  Endocrine resistance
sara04010  MAPK signaling pathway
sara04015  Rap1 signaling pathway
sara04068  FoxO signaling pathway
sara04071  Sphingolipid signaling pathway
sara04114  Oocyte meiosis
sara04148  Efferocytosis
sara04218  Cellular senescence
sara04261  Adrenergic signaling in cardiomyocytes
sara04370  VEGF signaling pathway
sara04380  Osteoclast differentiation
sara04550  Signaling pathways regulating pluripotency of stem cells
sara04611  Platelet activation
sara04613  Neutrophil extracellular trap formation
sara04620  Toll-like receptor signaling pathway
sara04621  NOD-like receptor signaling pathway
sara04622  RIG-I-like receptor signaling pathway
sara04625  C-type lectin receptor signaling pathway
sara04657  IL-17 signaling pathway
sara04658  Th1 and Th2 cell differentiation
sara04659  Th17 cell differentiation
sara04660  T cell receptor signaling pathway
sara04664  Fc epsilon RI signaling pathway
sara04668  TNF signaling pathway
sara04670  Leukocyte transendothelial migration
sara04714  Thermogenesis
sara04722  Neurotrophin signaling pathway
sara04723  Retrograde endocannabinoid signaling
sara04728  Dopaminergic synapse
sara04750  Inflammatory mediator regulation of TRP channels
sara04912  GnRH signaling pathway
sara04914  Progesterone-mediated oocyte maturation
sara04917  Prolactin signaling pathway
sara04926  Relaxin signaling pathway
sara04932  Non-alcoholic fatty liver disease
sara04933  AGE-RAGE signaling pathway in diabetic complications
sara04935  Growth hormone synthesis, secretion and action
sara04936  Alcoholic liver disease
sara05014  Amyotrophic lateral sclerosis
sara05020  Prion disease
sara05022  Pathways of neurodegeneration - multiple diseases
sara05132  Salmonella infection
sara05133  Pertussis
sara05135  Yersinia infection
sara05140  Leishmaniasis
sara05142  Chagas disease
sara05145  Toxoplasmosis
sara05152  Tuberculosis
sara05161  Hepatitis B
sara05163  Human cytomegalovirus infection
sara05167  Kaposi sarcoma-associated herpesvirus infection
sara05169  Epstein-Barr virus infection
sara05170  Human immunodeficiency virus 1 infection
sara05171  Coronavirus disease - COVID-19
sara05205  Proteoglycans in cancer
sara05208  Chemical carcinogenesis - reactive oxygen species
sara05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
sara05415  Diabetic cardiomyopathy
sara05417  Lipid and atherosclerosis
sara05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:sara00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101554044 (MAPK11)
   04015 Rap1 signaling pathway
    101554044 (MAPK11)
   04370 VEGF signaling pathway
    101554044 (MAPK11)
   04668 TNF signaling pathway
    101554044 (MAPK11)
   04068 FoxO signaling pathway
    101554044 (MAPK11)
   04071 Sphingolipid signaling pathway
    101554044 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    101554044 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    101554044 (MAPK11)
   04218 Cellular senescence
    101554044 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    101554044 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101554044 (MAPK11)
   04613 Neutrophil extracellular trap formation
    101554044 (MAPK11)
   04620 Toll-like receptor signaling pathway
    101554044 (MAPK11)
   04621 NOD-like receptor signaling pathway
    101554044 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    101554044 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    101554044 (MAPK11)
   04660 T cell receptor signaling pathway
    101554044 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    101554044 (MAPK11)
   04659 Th17 cell differentiation
    101554044 (MAPK11)
   04657 IL-17 signaling pathway
    101554044 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    101554044 (MAPK11)
   04670 Leukocyte transendothelial migration
    101554044 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    101554044 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    101554044 (MAPK11)
   04917 Prolactin signaling pathway
    101554044 (MAPK11)
   04926 Relaxin signaling pathway
    101554044 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    101554044 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101554044 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    101554044 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    101554044 (MAPK11)
   04722 Neurotrophin signaling pathway
    101554044 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101554044 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101554044 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    101554044 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    101554044 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    101554044 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101554044 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101554044 (MAPK11)
   05161 Hepatitis B
    101554044 (MAPK11)
   05171 Coronavirus disease - COVID-19
    101554044 (MAPK11)
   05163 Human cytomegalovirus infection
    101554044 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101554044 (MAPK11)
   05169 Epstein-Barr virus infection
    101554044 (MAPK11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101554044 (MAPK11)
   05135 Yersinia infection
    101554044 (MAPK11)
   05133 Pertussis
    101554044 (MAPK11)
   05152 Tuberculosis
    101554044 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101554044 (MAPK11)
   05140 Leishmaniasis
    101554044 (MAPK11)
   05142 Chagas disease
    101554044 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101554044 (MAPK11)
   05020 Prion disease
    101554044 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    101554044 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101554044 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    101554044 (MAPK11)
   05415 Diabetic cardiomyopathy
    101554044 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101554044 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    101554044 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101554044 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101554044 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:sara01001]
    101554044 (MAPK11)
Enzymes [BR:sara01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     101554044 (MAPK11)
Protein kinases [BR:sara01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   101554044 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 APH RIO1 Cas_CT1975 Kinase-like FTA2
Other DBs
NCBI-GeneID: 101554044
NCBI-ProteinID: XP_004610638
LinkDB
Position
Unknown
AA seq 364 aa
MSGPRAGFYRQELNQTLWEVPLRLQGLRPVGSGAYGSVCSAYDAQLRQKVAVKKLSRPFQ
SLVHARRTYRELRLLKHLKHENVITLLDVFTPATSIEDFSEVYLVTTLMGADLNSIVKCQ
ALSDEHIQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELKILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLRSIFRGASPLAVDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPDDEPEAEPYDHSLEAAEHTLEQWKELTYQEVLSFKPPEPAQPPGSL
EIEQ
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgtcgggcccccgcgccggcttctaccgccaggagctgaaccagacgctgtgggaggtg
ccgctgcggctgcagggcctgcggccggtgggctccggcgcctacggctccgtgtgctcg
gcctatgatgcgcaattgcgccagaaagtggcggtgaagaaactgtcacgaccgttccag
tctctggtccacgcgcggaggacctacagggaactgcggctgctcaagcacctcaaacac
gagaatgtcatcacgctcctggatgtcttcacaccagccacgtccatcgaggacttcagc
gaagtgtacctggtcaccaccctgatgggcgccgacctgaacagcatcgtcaagtgccag
gctctgagcgatgagcacatccagttcctggtgtaccagctgctgcgtgggctgaagtac
atccactcggccggcatcatccaccgggacctgaagcccagcaatgtggctgtgaacgag
gactgtgagctcaagatcctggacttcgggctggctcgccaagcggacgaggagatgact
ggctacgtggccacgcgctggtaccgagccccggagatcatgctgaactggatgcattac
aaccagacagtggacatctggtcagtgggctgcatcatggccgagctgctccaggggaag
gccctcttcccgggaagcgactatatcgaccaacttaagcgcatcatggaggtggtgggg
acgcccagccctgaggttctggcgaagatttcctcggaacacgcccggacctacatccag
tccctgcctcccatgccccagaaggacctcaggagcatcttccggggagccagccccctg
gccgtggacctcctgggaaggatgctggtactggacagcgaccagagggtcagtgcggca
gaggcactggcccacgcctacttcagccagtaccacgaccccgacgacgagcccgaggcc
gagccctatgaccacagcctggaggccgcggagcacacactggagcagtggaaggagctc
acctatcaggaggtgctcagctttaaacccccggagccagcccagccgccaggcagcctg
gagatcgagcagtga

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