Sorex araneus (European shrew): 101555141
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Entry
101555141 CDS
T07854
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
sara
Sorex araneus (European shrew)
Pathway
sara00140
Steroid hormone biosynthesis
sara01100
Metabolic pathways
sara05215
Prostate cancer
Module
sara_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
sara00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
101555141 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
101555141 (SRD5A2)
Enzymes [BR:
sara01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
101555141 (SRD5A2)
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SSDB
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Paralog
GFIT
Motif
Pfam:
Steroid_dh
DUF1295
DUF6832
Motif
Other DBs
NCBI-GeneID:
101555141
NCBI-ProteinID:
XP_004616127
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All DBs
Position
Unknown
AA seq
254 aa
AA seq
DB search
MPDGCQQSPVLAGSATLAILGALVLYQRTPNSYGKHTTSSASAAPLLPARAAWFLQELPS
FAVPAGMLARQPRALFGPPATLLLGLFCAHYFHRTFIYSLLTRGRPYPVLYTFNGFIFCM
GNGLLQGYYLMHCVDYPDEWYTDIRFSLGIFLFFLGMGINIHSDLILRQLRKPGETTYQI
PKGGLFTYVSGANFLGEIVEWIGFALATWSLPALAFAFFSLCFLGLRAFHHHRFYLRMFK
DYPKSRKALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgcccgacggctgccagcagagtccggtgctggcgggcagcgccacgctggccatcctg
ggggccctggtcctgtaccagcggacgcccaacagctacggcaagcacacgacgagctcg
gcgtcggcggccccgctgctgcccgcgcgcgccgcctggttcctgcaggagctgccctcc
ttcgccgtgcccgcgggcatgctggcccggcagccccgcgctctcttcgggccgccggcc
acgctgctgctgggactcttctgcgcgcattacttccacaggacattcatttactctttg
ctcactagagggagaccttatccagttctgtacactttcaatggctttattttctgcatg
ggaaacggacttctccaaggctactatctgatgcactgtgttgactacccagacgagtgg
tacacagacatccgcttcagcctgggtatcttcttattttttttgggaatgggaatcaat
attcatagtgaccttatactgcggcagctcaggaagcctggagaaaccacctatcagatt
ccgaaaggcggcttgtttacgtacgtttccggagccaatttcctcggtgagattgtggaa
tggatcggcttcgccctggccacctggtccctcccagcactcgccttcgcatttttctcg
ctctgtttcctcgggttgcgagcttttcaccaccataggttctatctcaggatgttcaag
gactaccccaaatctcgaaaagccctcattccattcatcttttaa
DBGET
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