KEGG   Sorex araneus (European shrew): 101555243
Entry
101555243         CDS       T07854                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
sara  Sorex araneus (European shrew)
Pathway
sara04120  Ubiquitin mediated proteolysis
sara04380  Osteoclast differentiation
sara04630  JAK-STAT signaling pathway
sara04668  TNF signaling pathway
sara04910  Insulin signaling pathway
sara04917  Prolactin signaling pathway
sara04920  Adipocytokine signaling pathway
sara04930  Type II diabetes mellitus
sara04931  Insulin resistance
sara04932  Non-alcoholic fatty liver disease
sara04935  Growth hormone synthesis, secretion and action
sara05160  Hepatitis C
sara05164  Influenza A
sara05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:sara00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    101555243 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    101555243 (SOCS3)
   04668 TNF signaling pathway
    101555243 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    101555243 (SOCS3)
   04920 Adipocytokine signaling pathway
    101555243 (SOCS3)
   04917 Prolactin signaling pathway
    101555243 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    101555243 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101555243 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    101555243 (SOCS3)
   05164 Influenza A
    101555243 (SOCS3)
   05168 Herpes simplex virus 1 infection
    101555243 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    101555243 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    101555243 (SOCS3)
   04931 Insulin resistance
    101555243 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:sara04121]
    101555243 (SOCS3)
Ubiquitin system [BR:sara04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     101555243 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 101555243
NCBI-ProteinID: XP_004621096
LinkDB
Position
Unknown
AA seq 225 aa
MVTHSKFPAAGMSRPLDASLRLKTFRSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPPPGAPAAPPAPPEPAAPPSAEVPEQPPPGAPPRRAYYIYSGGEKIPLVLSR
PLSSNVATLQHLCRKTVNGHLGSYEKVTQLPGPIREFLDQYDAPL
NT seq 678 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgcccgctggacgccagcctg
cgcctcaagaccttccgctccaagagcgagtaccagctggtggtgaacgccgtgcgcaag
ctgcaggagagcggcttctactggagcgccgtgaccggcggcgaggccaacctcctgctc
agcgccgagccggccggcaccttcctcatccgcgacagctcggaccagcgccacttcttc
acgctcagcgtcaagacgcagtcgggcaccaagaacctgcgcatccagtgcgagggcggc
agcttctccctgcagagcgacccccgcagcacgcagcccgtgccgcgcttcgactgcgtg
ctcaagctggtgcaccattacatgccgccccccggcgcccccgccgcgccgccggcgccc
cccgagccagccgcgccgccctccgccgaggtgccagagcagccgccccccggcgccccg
ccccggagagcctattacatctactcggggggcgagaagatccccctggtcctgagccgg
cccctctcctccaacgtggccacgctccagcatctctgtcggaagacagtcaacggtcac
ctgggctcctacgagaaggtcacccagctgcccgggcccatccgggagttcctggatcag
tacgacgccccgctttag

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