KEGG   Sorex araneus (European shrew): 101555912
Entry
101555912         CDS       T07854                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3 isoform X1
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
sara  Sorex araneus (European shrew)
Pathway
sara04010  MAPK signaling pathway
sara04015  Rap1 signaling pathway
sara04218  Cellular senescence
sara04620  Toll-like receptor signaling pathway
sara04664  Fc epsilon RI signaling pathway
sara04668  TNF signaling pathway
sara04714  Thermogenesis
sara04750  Inflammatory mediator regulation of TRP channels
sara04912  GnRH signaling pathway
sara04935  Growth hormone synthesis, secretion and action
sara04936  Alcoholic liver disease
sara05014  Amyotrophic lateral sclerosis
sara05022  Pathways of neurodegeneration - multiple diseases
sara05132  Salmonella infection
sara05135  Yersinia infection
sara05145  Toxoplasmosis
sara05161  Hepatitis B
sara05169  Epstein-Barr virus infection
sara05170  Human immunodeficiency virus 1 infection
sara05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
sara05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:sara00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101555912 (MAP2K3)
   04015 Rap1 signaling pathway
    101555912 (MAP2K3)
   04668 TNF signaling pathway
    101555912 (MAP2K3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    101555912 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101555912 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    101555912 (MAP2K3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    101555912 (MAP2K3)
   04935 Growth hormone synthesis, secretion and action
    101555912 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101555912 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    101555912 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101555912 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101555912 (MAP2K3)
   05161 Hepatitis B
    101555912 (MAP2K3)
   05169 Epstein-Barr virus infection
    101555912 (MAP2K3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101555912 (MAP2K3)
   05135 Yersinia infection
    101555912 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101555912 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101555912 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    101555912 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101555912 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101555912 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:sara01001]
    101555912 (MAP2K3)
Enzymes [BR:sara01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     101555912 (MAP2K3)
Protein kinases [BR:sara01001]
 Serine/threonine kinases: STE group
  STE7 family
   101555912 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Seadorna_VP7 Pkinase_fungal Choline_kinase APH RIO1 DUF4344
Other DBs
NCBI-GeneID: 101555912
NCBI-ProteinID: XP_004612868
LinkDB
Position
Unknown
AA seq 346 aa
MESPASSQPAGMPQPKEKTKRKKLRISCVPKPPVPNPTPPRNLDSRTFITIGDKNFEVEA
DDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDVNMRTVDCF
YTVTFYGALFREGDVWICMELMDTSLDKFYRKVLEKNMTIPEDILGEIAVSIVRALEHLH
SKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELN
QKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVDF
TAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVQEILGEDS
NT seq 1041 nt   +upstreamnt  +downstreamnt
atggagtcgcccgcctcgagtcaacccgccggcatgccccagcccaaagaaaagaccaag
agaaagaagttacgaatatcatgtgtgcccaagccacctgtgcccaaccccacgcccccc
cggaacctggactcccggacattcatcaccatcggagataagaactttgaggtggaggcc
gacgacctggtcaccatctcggagctgggccgtggtgcctacggggtggtggagaaggtg
cggcatgcccagagcggcaccatcatggccgtgaagcggatccgggccactgtgaactcg
caggagcagaagcggctgctcatggacctggacgtcaacatgcgtaccgtggactgcttc
tacactgtcaccttctacggggccctctttagagagggagatgtctggatctgcatggag
ctcatggatacatcccttgacaaattctaccggaaggtgctggagaagaacatgacgatt
cccgaagacattctgggggagattgctgtgtctatcgtcagggccctggagcatctgcac
agcaagctctcggtcatccacagagatgtgaaaccgtccaacgtcctcatcaacaaggag
ggccacgtgaagatgtgcgacttcggcatcagcggctacttggtggactcggtggccaag
acaatggatgccggctgcaagccctacatggctcccgagagaatcaacccggagctgaac
cagaagggctacaacgtcaagtccgatgtctggagccttggcatcaccatgattgagatg
gccattctccggtttccatatgagtcctgggggaccccgttccagcagctgaagcaggtg
gtagaagagccgtcaccgcagcttcctgccgaccgcttctcccccgaatttgtagacttc
actgcgcagtgcctgaggaagaacccagcagagcgcatgagctacttggagctgatggag
caccctttcttcaccttgcacaaaaccaagaagacggacatcgctgcctttgtgcaggag
atcctgggggaagactcgtag

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