Sorex araneus (European shrew): 101556630
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Entry
101556630 CDS
T07854
Symbol
ITPR2
Name
(RefSeq) inositol 1,4,5-trisphosphate receptor type 2
KO
K04959
inositol 1,4,5-triphosphate receptor type 2
Organism
sara
Sorex araneus (European shrew)
Pathway
sara04020
Calcium signaling pathway
sara04022
cGMP-PKG signaling pathway
sara04070
Phosphatidylinositol signaling system
sara04114
Oocyte meiosis
sara04210
Apoptosis
sara04218
Cellular senescence
sara04270
Vascular smooth muscle contraction
sara04371
Apelin signaling pathway
sara04380
Osteoclast differentiation
sara04540
Gap junction
sara04611
Platelet activation
sara04621
NOD-like receptor signaling pathway
sara04625
C-type lectin receptor signaling pathway
sara04720
Long-term potentiation
sara04723
Retrograde endocannabinoid signaling
sara04724
Glutamatergic synapse
sara04725
Cholinergic synapse
sara04726
Serotonergic synapse
sara04728
Dopaminergic synapse
sara04730
Long-term depression
sara04750
Inflammatory mediator regulation of TRP channels
sara04912
GnRH signaling pathway
sara04915
Estrogen signaling pathway
sara04918
Thyroid hormone synthesis
sara04921
Oxytocin signaling pathway
sara04922
Glucagon signaling pathway
sara04924
Renin secretion
sara04925
Aldosterone synthesis and secretion
sara04927
Cortisol synthesis and secretion
sara04928
Parathyroid hormone synthesis, secretion and action
sara04929
GnRH secretion
sara04934
Cushing syndrome
sara04935
Growth hormone synthesis, secretion and action
sara04970
Salivary secretion
sara04971
Gastric acid secretion
sara04972
Pancreatic secretion
sara05010
Alzheimer disease
sara05012
Parkinson disease
sara05017
Spinocerebellar ataxia
sara05020
Prion disease
sara05022
Pathways of neurodegeneration - multiple diseases
sara05163
Human cytomegalovirus infection
sara05167
Kaposi sarcoma-associated herpesvirus infection
sara05170
Human immunodeficiency virus 1 infection
sara05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
sara00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
101556630 (ITPR2)
04020 Calcium signaling pathway
101556630 (ITPR2)
04070 Phosphatidylinositol signaling system
101556630 (ITPR2)
04022 cGMP-PKG signaling pathway
101556630 (ITPR2)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
101556630 (ITPR2)
04210 Apoptosis
101556630 (ITPR2)
04218 Cellular senescence
101556630 (ITPR2)
09144 Cellular community - eukaryotes
04540 Gap junction
101556630 (ITPR2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101556630 (ITPR2)
04621 NOD-like receptor signaling pathway
101556630 (ITPR2)
04625 C-type lectin receptor signaling pathway
101556630 (ITPR2)
09152 Endocrine system
04922 Glucagon signaling pathway
101556630 (ITPR2)
04929 GnRH secretion
101556630 (ITPR2)
04912 GnRH signaling pathway
101556630 (ITPR2)
04915 Estrogen signaling pathway
101556630 (ITPR2)
04921 Oxytocin signaling pathway
101556630 (ITPR2)
04935 Growth hormone synthesis, secretion and action
101556630 (ITPR2)
04918 Thyroid hormone synthesis
101556630 (ITPR2)
04928 Parathyroid hormone synthesis, secretion and action
101556630 (ITPR2)
04924 Renin secretion
101556630 (ITPR2)
04925 Aldosterone synthesis and secretion
101556630 (ITPR2)
04927 Cortisol synthesis and secretion
101556630 (ITPR2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
101556630 (ITPR2)
09154 Digestive system
04970 Salivary secretion
101556630 (ITPR2)
04971 Gastric acid secretion
101556630 (ITPR2)
04972 Pancreatic secretion
101556630 (ITPR2)
09156 Nervous system
04724 Glutamatergic synapse
101556630 (ITPR2)
04725 Cholinergic synapse
101556630 (ITPR2)
04728 Dopaminergic synapse
101556630 (ITPR2)
04726 Serotonergic synapse
101556630 (ITPR2)
04720 Long-term potentiation
101556630 (ITPR2)
04730 Long-term depression
101556630 (ITPR2)
04723 Retrograde endocannabinoid signaling
101556630 (ITPR2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101556630 (ITPR2)
09158 Development and regeneration
04380 Osteoclast differentiation
101556630 (ITPR2)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
101556630 (ITPR2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
101556630 (ITPR2)
05163 Human cytomegalovirus infection
101556630 (ITPR2)
05167 Kaposi sarcoma-associated herpesvirus infection
101556630 (ITPR2)
09164 Neurodegenerative disease
05010 Alzheimer disease
101556630 (ITPR2)
05012 Parkinson disease
101556630 (ITPR2)
05017 Spinocerebellar ataxia
101556630 (ITPR2)
05020 Prion disease
101556630 (ITPR2)
05022 Pathways of neurodegeneration - multiple diseases
101556630 (ITPR2)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
101556630 (ITPR2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
sara04040
]
101556630 (ITPR2)
Ion channels [BR:
sara04040
]
Ligand-gated channels
IP3 receptor
101556630 (ITPR2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ins145_P3_rec
RYDR_ITPR
Ion_trans
MIR
RIH_assoc
C_GCAxxG_C_C
Motif
Other DBs
NCBI-GeneID:
101556630
NCBI-ProteinID:
XP_012788828
LinkDB
All DBs
Position
Unknown
AA seq
2375 aa
AA seq
DB search
MSEKMSSFLYIGDIVSLYAEGAVSGFISTLGLVDDRCVVHPEAGDLSNPPKKFRDCLFKV
CPMNRYSAQKQYWKAKQAKQGNHTEAALLKKLQHAAELEQKQNESENKKLLGEVVKYSNV
IQLLHIKSNKYLTVNKRLPALLEKNAMRVALDAAGNEGSWFYIHPFWKLRSEGDNIVVGD
KVVLMPVNAGQPLHASNMELLDNPGCKEVNAVNCNTSWKITLFMKYSSYREDMLKGVVHH
DPCRGGAGQWNSLFRFKHLATGNYLAAERDGEMPASKKKRQAGEKIMYTLVSVPHGNDIA
SLFELDATTLQRADCLVPRLEDLIFFVADVLNNGQEVLDVVVTKPNRERQKLMREQNILA
QVFGILKAPFKEKAGEGAMLRLEDLGDQRYAPYKYLLRLCYRVLRHSQRDYRKNQEYIAR
NFCVMQSQIGYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSD
LCVSNTTAIPVTQELICKFMLSPGNADILIQTKLVSMQMDNPMEPSILADDVDEDEVWLY
WIDSNKEPHGKAIRHLAQEAKEGTKADLEVLTYYRFQLNLFARMCLDRQYLAIDQISTQL
SVDLILRCVADESLPFDLRASFCRLMLHMHVDRDPQEPVVPVRYARLWTEIPTKISIHEY
DSITDSSRSDMKRKFALTMAFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGF
YSFSELLRLTRTLLAILDIVQVPLSSYLERLSKFQDGGNNVMRTIHGVGEMMTQMVLSRG
SIFPVSIPDGPASALPSKQGGGGEQEDVTVMDTKLKIIEILQFILSVRLDYRISYMLSIY
KKEFGESSENADASPSGTPDMLLPSAVVPDIHEIAAQAETMFAGRKEKNPVQLDDEGGRT
FLRVLIHLIMHDYPPLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADL
DQLRLTVEKSELWVEKSGGYESGELGEGQGKAAEEPLELLEAETMRHIFMDNYPLCCELS
ERVVQHFVRCVETHGRHVQYLRFLQTVVKADGKYVKKCQDMVMTELINGGEDVLIFYNDR
ASFPVLLRMMCSERDRGDESGPLAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRV
VTHDDCIPEVKIAYVNFVNHCYVDTEVEMKEIYTSNHIWKLFENFLVDMARVCNTTTDRK
HADTFLEKCVTESIMSIVSGFFNSPFSDNSTSLQTHQPVFTQLLQSAFRVYNCTWPSPAQ
KASVESCVRTLAEVAKNRGIAIPVDLDSQVNTLFLKSHSSTVQRAALGWRLSARSGPRFK
EALGGPAWDYRNIIEKLQDVVASLEQQLSPMMQAEFSVLVDVLYSPELLFPEGSDARIRC
SAFMSKLINHTKKLMEKEEKLCIKILQTLREMLEKKDSFVEEGTTLRKILLNRYFKGDHG
AGAGSALSGTYPKPAPGGGSFSGPDADKAGTSLSDIQCLLDREGASELVIDVIVSTKNDR
IFSEAILLGIALLEGGNTQTQYSFYQQLHEQKKSEKFFKVLYDRMKAAQKEIRSTVTVST
ADLGSKGTDDDSERLMVSPRPRGRDVCPALREGMKGQLSEASSATSKAYCMYRRDADADL
DLAGAGSDGGSGGEKPAEEASTGPAIANFLRNQNNKTNYNLVCETLQFLDCICGSTTGGL
GLLGLYINEKNVALVNQTLESLTEYCQGPCHENQTCIATHESNGIDIIIALILNDINPLG
KYRMDLVLQLKNNASKLLLAIMESRHDSENAERILFNMRPRELVDVMKNAYNQGLECDQA
AEEGREDVISPKDVGHNMYILAHQLARHNKLLQQMLKPGPDADDGDEALRHYANHTAQIE
IVRHDRTMEQIVFPVPSICEFLTQESKVRVLATTERDEQGSKVNDFFQQTEDLYNEMKWQ
KKIRNNPALFWFSRHISLWGSISFNLAVLINLAVALFYPFGDDGDEGTLSPLSSVLLWVA
VAVCTSLLFLFSKPAGIRPFLVCVMLRSIYTVGLAPTLVLLGAANLCNKIVFLVSFVGNR
GTFTRGYRAVILDVAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTR
NGRSIILTAVLALILVYLFSIVGFLFLKDDFTMEVDRLKNRTPAAGGGDVPTMTLPSLAD
TCLKENCSPTIPASPDEEEPGGGVERTCDTLLMCIVTVLNQGLRNGGGVGDVLRRPSKDE
PLFAARVVYDLLFYFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDK
FDNKTVSFEEHIKAEHNMWHYLYFLVLVRVKDPTEYTGPESYVAQMIVSINSKQDMQDIS
SELYGESKQNLTVSTQKRMKKNLISLLKKVKSGEK
NT seq
7128 nt
NT seq
+upstream
nt +downstream
nt
atgtccgagaagatgtccagcttcctgtacatcggggacatcgtgtccctgtacgccgag
ggcgccgtgagcggcttcatcagcacgctggggctggtggacgaccgctgtgtggtgcac
cccgaggcgggggacctcagcaaccccccgaagaagttcagagactgcctcttcaaggtg
tgccccatgaaccgctactcggcgcagaagcagtactggaaggccaagcaggccaagcag
ggcaaccacacggaggccgccctgctcaagaagctgcagcacgccgcggagctggagcag
aagcagaacgagtcggagaacaagaagctgctgggggaggtggtgaagtacagcaacgtc
atccagctgctgcacatcaaaagcaacaagtacctgacggtcaacaagcggctgcccgca
ctgctggagaagaacgccatgcgcgtggccctggacgccgccggcaacgagggctcctgg
ttctacatccaccccttctggaagctgaggagcgagggcgacaacatcgtcgtaggggac
aaggtggtgctgatgcccgtgaacgccgggcagcccctgcacgccagcaacatggagctg
ctggacaacccgggctgcaaggaggtcaacgccgtcaactgcaacacaagctggaaaatc
acgctgttcatgaagtacagctcctaccgcgaggacatgctgaaaggagtggtccaccac
gacccctgccgcggaggcgccggacagtggaacagcttgttcaggttcaagcatctcgca
acggggaactatttggctgccgagagagacggagaaatgccagcctcgaagaagaagcgg
caggcgggggagaagatcatgtacacgctggtgtctgtgccacacgggaacgacatcgcg
tctctcttcgagctggacgccacgactctccagagggccgattgcctggtgccgaggctg
gaggatctcatcttctttgtcgccgacgtgctgaacaacggacaggaggtcctggacgtg
gtcgtcaccaagccaaaccgcgagcgccagaagctgatgcgcgaacagaacatactggcg
caggtgttcgggatcctgaaggcgcccttcaaggagaaggcaggcgagggggccatgctg
aggctggaggacctgggcgaccagagatacgccccctacaagtacctcctgcgcctgtgc
taccgcgtcctgcgccactcccagcgggactaccgcaagaaccaggaatacatcgcgagg
aacttctgcgtcatgcagtcccagatcggctacgacatcctggccgaggacaccatcaca
gccctgctgcacaacaacaggaagctgctggagaagcacatcacggccaaggagatagag
accttcgtcagcctgctgcggaggaaccgcgagcccagatttctggattatttatcagat
ctctgcgtgtcgaataccaccgctatccccgtcacccaagaactcatctgtaaattcatg
ctgagcccggggaacgctgacatcctcatccagaccaagctggtctccatgcagatggac
aaccccatggagccgtccatcctggccgacgacgtggacgaggacgaagtctggctgtac
tggatcgacagcaacaaggagcctcacggcaaggccatcaggcacctggcccaggaggcc
aaggagggcaccaaggcggacctggaggtgctcacctactacaggttccagctgaacctg
tttgcgcggatgtgcctggaccgccagtacctggccatcgaccagatctccacgcagctg
tcggtggacctgatcctgcgctgcgtggcggacgagagcctgcccttcgacctgcgcgcg
tccttctgccggctgatgctgcacatgcacgtggaccgcgacccgcaggagcccgtggtg
cccgtgcgctacgcccggctctggaccgagatccccaccaagatcagcatccacgagtac
gactccatcaccgactcctccaggagcgacatgaagaggaagttcgcgctgaccatggcg
ttcgtggaggagtacctgaaggaggtggtcaaccagcccttccccttcggggacaaggag
aagaacaagctgaccttcgaggtggtgcacttggcccggaacctcatttacttcggcttc
tacagcttcagcgagctgctgaggctgacgaggacgctgctggccatcctggacatcgtc
caggtccccctgtcgtcgtacctggaaagattaagcaagttccaagatggaggaaacaac
gtcatgaggaccatccacggggtgggcgagatgatgacgcagatggtgctcagccgcggc
tccatcttccccgtgagcatccccgacgggccggccagcgccctccccagcaagcagggg
ggcggcggcgagcaggaggacgtgaccgtcatggacaccaagctgaagatcatcgagatc
ctccagttcatcctgagcgtcaggctggactacaggatctcgtacatgctgtccatctac
aagaaggagtttggcgagagcagcgagaacgcagacgcctcccccagtggcaccccggac
atgctgctgccctcagctgtggttccggacatccacgagatcgcggcgcaggccgagacc
atgtttgccggaaggaaggagaagaatcccgtccagctggacgacgagggcggccgcacg
ttcctgcgggtcctcatccacctgatcatgcacgactacccgccgctgctctcgggggcc
ctgcagctgctcttcaagcacttcagccagagggccgaggtcctgcaggccttcaagcag
gtgcagttgctggtgtccaaccaagacgtggacaactacaagcagatcaaggccgacctg
gaccagctgcgcctgaccgtggagaagtcggagctgtgggtggagaagagcggcggctac
gagagtggagagctgggcgagggccagggcaaggctgccgaggagccgctcgagctcctg
gaggcggagaccatgcggcacatcttcatggacaactacccgctgtgctgcgagctgagt
gagcgcgtggtgcagcacttcgtgcgctgcgtggagacgcacgggcgccacgtgcagtac
ctgcgcttcctgcagaccgtggtcaaggccgacggcaagtacgtgaagaagtgccaggac
atggtgatgaccgagctgatcaacggcggtgaggacgtgctgatattctacaacgaccgg
gcgtcgttccccgtcctcctccgcatgatgtgctcggagagggaccgcggggacgagagc
ggccccctggcctaccacatcacactcgtggagctgctggcggcctgcaccgagggcaag
aacgtctacaccgagatcaagtgcaactccttgctgcccctggacgacatcgtgagggtg
gtgacccacgatgactgcatccccgaggtgaaaatcgcttacgtgaattttgtcaaccac
tgctatgtggacactgaagtggagatgaaggaaatctacacgagcaaccacatttggaaa
ttattcgagaacttcctggtggatatggcacgggtgtgcaacaccacgacggacaggaag
cacgcggacaccttcctggagaagtgtgtcaccgagtccatcatgagcatcgtcagcggc
ttcttcaactcgcccttctcggacaacagcaccagcctgcagacgcaccagcccgtgttc
acccagctgctgcagtcggccttccgcgtgtacaactgcacctggcccagcccggcccag
aaggcctcggtggagtcctgtgtgcggacgctggccgaagtggcaaagaatcgtggcatt
gccattcctgtggacctggacagccaagtgaacaccctcttcctgaagtcccactccagc
accgtgcagagggcggccctgggctggagactgtccgctcgctccggaccccgcttcaag
gaagctctgggcgggccggcgtgggattacagaaatatcatcgagaagctgcaggacgtg
gtggcctccctggagcagcagctgagccccatgatgcaggcggagttctcggtgctggtg
gacgtgctctacagccccgagctgctgttccccgagggcagcgacgcccgcatccggtgc
agtgccttcatgtccaagttgattaatcatacaaaaaaactaatggaaaaggaagaaaaa
ttgtgcatcaaaattctccagactttacgagaaatgctagagaagaaggacagctttgtg
gaagagggaaccacgttgaggaaaatcctcctgaaccgatacttcaaaggcgaccatgga
gccggggcgggcagcgccctctcggggacctacccgaagcctgcgcccggaggagggagc
ttctccggaccggacgcggacaaggcgggcacctccctgtcggacatccagtgcctgctg
gacagggagggggcctcggagctggtcatagacgtcatcgtgagcaccaagaacgaccgc
atcttctcggaggccatcctgctgggcatcgcgctgctggagggcgggaacacgcagacg
cagtattctttctaccagcagctgcacgagcaaaaaaagtcagaaaaattcttcaaagtt
ctctatgaccgaatgaaggcggctcagaaggagatcagatccacggtcaccgtgagcacc
gcggacctgggcagcaaggggacggacgacgacagcgagcggctgatggtcagcccccgc
ccgcgagggagagacgtgtgcccggccctgcgggagggcatgaaggggcagctgagcgag
gcctcctcggccacctccaaggcctactgcatgtaccggcgggatgcggacgccgacctg
gacctcgcgggcgcgggctcggacgggggcagcggtggggagaagccggcggaggaggcg
agcacgggcccggccatcgccaatttcctgaggaaccagaacaacaaaaccaactacaac
ctggtgtgcgagacgctgcagttcctggactgcatctgcgggagcacgaccgggggcctg
gggctgctggggctctacatcaacgagaagaacgtggcgctggtcaaccagacgctggag
agcctcaccgagtactgccagggcccgtgccacgagaaccagacgtgcattgctactcat
gaatcgaatgggattgatatcatcattgctttgattctaaacgacataaaccctcttggc
aagtaccgcatggacctggtgctccaactcaagaacaacgcgtccaagctgctgctggcc
atcatggagagcagacacgacagcgagaacgccgagcggatcctgttcaacatgaggccc
cgggagctggtggacgtgatgaagaacgcctacaaccagggcctggagtgtgaccaggcc
gccgaggagggcagggaggacgtgatctcccccaaggacgtcggccacaacatgtacatc
ctggcccaccagctggcccggcacaacaagctcctgcagcagatgctgaagccggggccg
gacgcggacgacggggacgaggccctgcgacactacgccaaccacacggcccagatcgag
atcgtccggcacgacaggaccatggagcagatcgtgttcccggtgcccagcatctgcgag
ttcctgacgcaggagtccaaggtgcgggtgctggccaccacggagcgcgacgagcagggc
agcaaggtgaacgacttcttccagcagaccgaggacctctacaacgagatgaagtggcag
aagaagatccggaacaaccccgcgctcttctggttctcaagacacatctcgctgtggggc
agcatctccttcaacctggccgtgctcatcaacctggccgtggcgctcttctacccgttc
ggggacgacggggacgaaggcacgctgtcccccttgtcctcggtgctgctgtgggtcgcg
gtggccgtctgcacatctctgctcttcctcttctccaagcccgcgggcatccggcccttc
ctggtatgcgtgatgctcaggtccatctacaccgtcggcctcgcgcccacgctcgtcctc
ctgggcgcggccaacctctgtaacaagatcgtgttcctggtgagttttgtcgggaaccgc
ggcacgttcacgcgtggctaccgggcggtgatcctggacgtggccttcctctaccacgtg
gcctacgtgctggtctgcatgctgggactctttgtccacgagttcttctacagcttcctg
ctcttcgacctggtgtaccgcgaggagacgctgctgaacgtcatcaagagtgtgacccgc
aacggccgctccatcatcctgacggcggtgctggcgctcatcctcgtctacctcttctcc
atcgtcggcttcctcttcctcaaggacgacttcaccatggaggtggaccggctgaagaac
cgcacccccgccgcgggtggcggcgacgtcccaaccatgactctgccttccctggcggac
acctgcctcaaggagaactgctcccccaccatcccggccagcccagacgaggaggagccc
gggggcggcgtggagaggacgtgcgacaccctgctcatgtgcatcgtcaccgtgctgaac
cagggcctgcgcaacggcgggggcgtgggggacgtgctccggaggccttccaaggacgag
cccctgtttgccgcccgggtggtgtatgacctcctcttctacttcattgtcatcatcatc
gtcctcaacctgatcttcggcgtcatcatcgacacctttgccgacctcaggagcgagaag
cagaagaaggaggagattctcaagaccacctgcttcatctgcggactcgagagggacaag
ttcgacaacaagacggtctcgttcgaggagcacatcaaggcggagcacaacatgtggcac
tacctgtacttcctggtgctggtgcgggtgaaggaccccacggagtacacgggccccgag
agctacgtggcgcagatgatcgtgtctatcaactcaaagcaagacatgcaagatatttcg
tctgaactgtatggtgaatcgaagcaaaatctcacagtaagcacacaaaagagaatgaaa
aagaacttaatctcactgctaaagaaagttaaatcaggagaaaaatga
DBGET
integrated database retrieval system
