Sorex araneus (European shrew): 101557991 Help Entry 101557991         CDS       T07854                                  Symbol SETX Name (RefSeq) probable helicase senataxin   KO K10706   ATP-dependent RNA/DNA helicase, senataxin [EC:5.6.2.5 5.6.2.3] Organism sara  Sorex araneus (European shrew) Pathway sara05014   Amyotrophic lateral sclerosis Brite KEGG Orthology (KO) [BR:sara00001]  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     101557991 (SETX)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03021 Transcription machinery [BR:sara03021]     101557991 (SETX) Enzymes [BR:sara01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.3  DNA 5'-3' helicase      101557991 (SETX)     5.6.2.5  RNA 5'-3' helicase      101557991 (SETX) Transcription machinery [BR:sara03021]  Eukaryotic type   RNA polymerase II system    Other transcription-related factors     Transcription termination factor      101557991 (SETX) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AAA_11 AAA_12 SEN1_N AAA_19 UvrD-helicase AAA_30 AAA_22 SLFN-g3_helicase AAA_16 ResIII NAT10_TcmA_helicase UvrD_C_2 nSTAND3 Motif Other DBs NCBI-GeneID:  101557991 NCBI-ProteinID:  XP_004613497 LinkDB All DBs Position Unknown AA seq 2542 aa AA seqDB search MSTCCWCTPGGTSTVDFLKRYAAQPAQCSEFQTANEDLCYCLECVVEYHKARDELPLFHE VLWELEIVRLTNHFEKSMSAEIDDDDELYIVDMNGEAQLFDFAGQDFENKLRVPLLEILK FPYLLLHERVNELCVEALCRMEQANCSFQVFEKHPGIYLFLVHPNEMVRRWAILTAKSLG KVDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPAHMYDVTNYKNYWL GICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERPAEDDSMDPFWPALHCFMVILDR LGSKVWGQLIDPIEAFQTIINNVSYNREIQTIRKSSVRPKFEPEPYMADMVTCSQIVYNF NPEKTKKDPGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLM DLKDLGVAYILEVIHHLHSEVRDVLNQANAMCDKVTEFFLLILVSVVELHRNKRCLHLLW VSSQQWVEAVVKCAKLPTSAFARSAEKSAASGPRGSPVFSTLSLHTAQANSVQLACVQLI RSLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTAQETQELQMCLKQIIRNIKVKG PQSSTLAGLPPPCKNPRGSEEKDGPRPESSSPAPPKQPARAGGGREHEGAAGRAPKAAEE PEPGGSRPGGPLAPASACQQCREDLPDGGPEPGHGGAQGQRALGDLPPCTPTSRAPSRGP AGEPDGGIATAALSAGCSSHGPAQEAPQGEDSALKDGALGRSGRVKTKAQKDEFCAKLSH MIKQQHRKSPLVSSGVSGEETPTTSGVESLCSRKGAGDAGGDGGFLHGLCVGPHSVLGES SGDPAGAGASVLEKRQVQTDVLGTVSQESSRHARKREHDRALVSLIEATGNFARKTSPSE EPETIPGSQEVTGKMSRGALADDRDQPLSLSPRPDSLTDSQIDQDLYDLSLLAQASASKF PSESSQQSPCQLQRKVREDRRGFETKATSTRDARPSQVIVIYDSDEEEDGTLSAGQRSKA EPAGLAEAEQVVSVADSSVDDETLKEEQTKRLLEFEDSDSQFFEFETPCEVFSVWQDQKQ DKHSDWEGEEGSSVPRGSGAAEEQGRAGDAMPGRAATEGPTGSRGPAEPGASISAEEICE IKVKKRKRKRLEQPSAETSREPPAPAPSGEQPGGPPPAGQAAPAAPAAPRATKKAPSGAR AYFAPSGQGPAAKGAKKAQAEPRKGPPKTQYLKCRAVPAVVPPKKIRQFPEPTSTVERLG LKKAPRRAIDLSQRSRDSISELRDYGKVAGAVDTQKKTKLIVPQMLSVRNNKKLLTMQQP HLGRRQVPARGPKSRPGARKGAQRPQQGTEAGGPELAAADGRAGPDVFAEGLGKPFLKTG PGGARAGPSVSDGGARPADTAVVASGGPERHVGAAAGPQPEPDSDSDPECESLFLTQHDP QDMDLCSQVESDPETAAQGQGPRCDHRDSEETARARDAPKAAAAVFLKPAVPPPGPRPRP TNTKVFSSSHTSRLASLSRSLESSPAPPRPARSKASGAPPGPKAAPPPPPPKAASPPPPP PPKPALAPALPEARGPLSVLFSAPAAASRPVFRPTFAENRSLSTVTPASVLLSSQAISDA FIKEVLKWKLDMFVNFSQCGPPESLCQAITRHVPVCFQDSGEYFNVFFPLVILNTFETVA QDWSNSSDKSYSLLFRKFPADYKKHWEFVVHLDENELAKQLHPKENDLVFLVPERRGRER HEAERKRALEVQEHYCGFVQKFRRTSATHGGRSECCLSIQTQDRLPLHINQAVRCLVISS LVTTQRKLKAMSLLSGRNQLARAVLNPDPMDFCTKDLLTTSSERIISYLRDFNEDQKKAI ETAYAMVRHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTETQRRGRSDENSNAKIKQNR VLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINTEVLKFSLD SQVSHRMKRDLPSHVQDMHRRKECLDHQLDELSRQRALCRGAREKQRQELDDRIAKVSKE RQELASKIKEVQGRPQKAQSLIILESHVVCCTLSTSGGLLLEAAFRGQGGVPFSCVIVDE AGQACEVETLTPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFYKLLEEKVE QSLLGRMPVVQLTVQYRMHPDICLFPSTYVYNRSLKTNRATETARCSSDWPFQPYLVFDV GDGAERRDNDSYVNVQEIKLVMEIIKLIKEKRKDVTFRNIGVITHYRAQKTLIQRDLDRE FDRKGLAEVDTVDAFQGRQKDCIIVTCVRANSTQGSIGFLSSLQRLNVAITRAKYSLFIL GHLRTLMDNPHWNHLIQDAQRRGAIVKTCDRSYRHDALKILKLKAGTLQRSLTHPPAATP EPARPQGGLPSSTPDGGLTSTSSPYLTPPDSGESPVPTKDPEKAPVQDRLRDPRLLRRLG VSLEARGAVMGAPRPQSPQPPPACPVLGGLQELSGLLLSAHCPLDTLPPGELRAAGVPQR TEGWDKRPLGDSDSYPKRRKLL NT seq 7629 nt NT seq  +upstreamnt  +downstreamnt atgagcacgtgctgctggtgcaccccgggcggcacctccaccgtcgacttcctgaagcgc tatgcggcgcagccggcccagtgcagcgagttccagacagccaacgaggacctctgctac tgcctggagtgcgtggtggagtaccacaaggcgcgggacgagctgccgctcttccacgag gttttatgggaattagaaattgtacggctcacaaaccattttgagaaatccatgagtgcg gaaattgatgatgacgacgagctgtacatcgtggacatgaacggagaggcgcagctgttt gacttcgccggccaggacttcgagaacaagctccgcgtgccgcttctagagatcctaaag ttcccgtatctgctcttacacgagcgtgtcaatgagctgtgtgtggaggcgctgtgccgc atggagcaggcgaactgctccttccaggtgttcgagaagcaccccggcatctacttgttc ctggttcaccccaacgagatggtcaggcgttgggccatcctgactgccaagagcttgggg aaagtggacagagatgattattacgacttgcaggaggttctgacgtgcctgtttaaagtg attgaactggggctgctggagagcccagacatttacacctcctctgtcctcgagaagggc aaactgatcctcctgcccgcgcacatgtatgacgtcacgaattacaagaactattggcta gggatctgcatgctgctgaccatcctggaggagcaggccatggactcgctgctgctcggc tccgacaagcagaacgacttcatgcagtccatcctgcacaccatggagaggcccgccgag gatgacagcatggaccctttctggccggccttacattgtttcatggtgatcttggaccgc ctggggtcaaaggtctggggccagctcatcgatccgatcgaggcgtttcaaaccatcatt aacaacgtgagctacaacagagagatccagaccattcggaagagctctgtgaggcccaag ttcgagccggagccgtacatggctgacatggtgacttgtagccagatcgtgtacaacttc aaccctgagaagaccaagaaggacccaggctggcgctcggccatctgcccggattactgc cccaacatgtacgaggagatggagacgctggccagcgtgctgcagtcggacatcgggcag gacatgcgcgtgcacaacagcaccttcctgtggttcatccccttcgtccagtcgctcatg gacctcaaggacctgggcgtggcctacatcctggaggtcatccaccacctgcactcggag gtcagggacgtcctcaaccaggccaacgccatgtgtgacaaggtcaccgagttcttcctg ctcatcctggtgtcggtggtggagctgcacaggaacaagaggtgcctgcacctgctgtgg gtgagctcgcagcagtgggtcgaggcggtggtcaagtgcgccaagctcccgaccagcgcc ttcgcacgcagcgccgagaagtcggccgccagcggcccccggggctccccggtcttctcc acgctgtccctgcacacggcgcaggccaactcggtgcagctggcctgcgtgcagctcatc aggagcctgctcaaggagggctaccagctgggccagcagaccctgtgcaagcgcttctgg gacaagctgaacctgttcctcaggggcaacctgtccctgggctggcagctgaccgcgcag gagacccaggagctccagatgtgtctgaagcagattatccggaacatcaaggtcaagggc cctcagagcagcacgctcgcggggctgccgcctccgtgcaaaaacccccgggggagcgag gagaaagacgggccccgcccggagagttccagccccgcgccccctaaacagcctgcgaga gcgggcggcggccgggagcacgaaggggcggcggggagagccccgaaagctgccgaggag cctgagccgggaggctcccggccgggggggcccctcgcgcccgcgtctgcctgccagcag tgccgcgaggaccttcccgatggcgggcccgagccgggccacggcggtgcccaggggcag agggctctgggcgacctccccccctgcacgcccacgagccgcgcgccgagcagaggcccc gcaggggagccagacggaggaatcgccacagccgcgctctccgcgggctgcagctcgcac ggcccagcccaggaggccccgcagggcgaggactcggctctgaaggacggggctctcggc agaagtggaagggtcaagaccaaggcgcagaaagatgagttttgcgccaagttgtcgcac atgataaagcagcagcaccggaagagtcccctggtcagcagcggggtgagtggggaggag accccgaccacgtccggcgtcgagagcctctgctcgaggaaaggcgccggggacgcagga ggggacggcggcttcttgcacggtctctgtgtcggcccgcacagcgttctgggcgagagc agcggggacccggcgggtgccggcgcctcagtgctggagaagaggcaggtgcagaccgac gtgctcggtaccgtctcccaggaaagcagccgccacgcccggaaacgtgagcacgataga gccctggtctcgctcatagaggcgactggcaacttcgccaggaagacctctccctccgag gagccggagaccatcccgggctctcaagaggtgaccggcaagatgagcagaggggccctg gcggatgaccgggatcagcccctcagcctcagccccaggcctgactccctgacggactct cagatagaccaggatctctacgacctgtcgctgctggctcaggccagcgcgagtaagttc ccctccgagtcctcgcagcagagcccctgccagctgcagaggaaggtccgggaggacagg aggggcttcgagaccaaggcgaccagcaccagggacgcccgccccagccaggtcattgtc atctacgattccgatgaagaggaggacgggactctgagtgcggggcagcgctcgaaggcg gagcccgcgggcctggcggaggcggagcaggtggtttccgtggcggactcgagtgtggac gacgagaccttgaaggaggagcagacaaagcgcctgctggagttcgaagactcggactct cagtttttcgagtttgagaccccatgcgaagtgttttccgtttggcaagatcagaagcaa gacaagcattcagactgggagggcgaggaaggctcctctgtgccccgtggctcgggagcc gccgaggagcagggccgggccggtgacgccatgccgggaagggccgccacggaggggccc acgggcagccgggggccggcagagccaggggcgagcatttccgccgaggagatctgtgaa atcaaggtgaagaaacggaagcggaaacgcttggagcagccgagtgctgagacgtcccga gagccgcccgcccctgcaccaagtggggagcagcctggcggccccccgccggcagggcag gcggcccccgctgcgcccgctgctcccagggccacgaagaaggcgccttccggagcccgc gcttacttcgcacccagcggccagggcccggcggccaagggcgccaagaaggcgcaggcg gagccccggaaggggcccccgaagacccagtacctcaagtgtcgggccgtgcccgccgtc gtcccgcccaagaagatccgccagtttcccgagcccacgtcgacggtggagcggctggga ctgaagaaggcgcctcgcagggccatcgacctgtcccagaggtcgcgcgacagcatctcg gagctccgggactacggcaaggtggccggggcagttgatacccagaaaaagaccaaatta atcgtgccccagatgctctcggtcagaaataacaagaagctgctgaccatgcagcagccg caccttgggcggaggcaggtgccggcccgcggccccaagagcaggccaggtgccaggaag ggggcgcagcgcccccagcaggggaccgaggccgggggcccagagctggcagctgccgac ggcagagcaggccccgatgtcttcgctgagggcctggggaagcccttcctcaagaccggc cccgggggagccagagctgggcccagtgtgtcagacgggggcgccaggccggcagacacg gccgtggtggcctctggggggcccgagcgacacgtgggggcggccgccggcccgcagcca gagccggactccgacagcgaccccgagtgcgagagtctgttcctcacccagcacgacccg caggacatggacttgtgctcccaggtggagagtgaccccgaaaccgccgcgcagggccag ggccccaggtgtgaccacagggacagcgaggagaccgccagggcccgggatgcgcccaag gccgccgccgccgtgttcctcaagcccgccgtgccgccccctgggcccaggcctcggccc accaacaccaaagtcttcagctccagccacacctcgcgcctggcgagcctctccaggtct ctggagagcagccctgcgcccccgcgccccgccaggagcaaggccagcggggcgccgccc gggcccaaggccgcccccccacccccgccaccgaaggccgcctcgcccccgcccccgccc ccgcccaagcctgccctggcccctgcgctgcccgaggccaggggccccttgagcgtcctc ttctcggcgcccgctgcggcctccaggcccgtgttcaggccgacctttgccgagaacagg tccctgtccacggtcaccccggccagcgtcctcctgtcctcgcaggccatctccgacgcc ttcatcaaagaggtcttaaagtggaagctcgacatgttcgtgaacttcagccagtgcggg ccgcctgagagcctgtgccaggccatcacgaggcacgtgcccgtgtgcttccaggactcg ggcgagtacttcaacgttttcttcccgctggtgatactgaatacttttgaaacggtggca caggactggagcaactcctcggataaatcctattcgttgctgttccggaaattccctgcg gactataagaaacactgggagtttgtggttcatctggacgaaaacgaactggccaaacag ctccacccgaaggaaaacgatttggtgtttctggtccccgagagacggggccgggagagg cacgaagctgagcggaagcgcgcgctggaggtgcaggagcactactgcggcttcgtccag aaattccgccgcacctccgccacgcacggcggcaggtccgagtgctgcctctccatccag acgcaggaccggctgcccctgcacatcaaccaggccgtgcgctgtctggtcatcagctcc ctggtgaccacgcagaggaagctgaaggccatgtctctgctgagtggccggaaccagctg gccagagccgtgctcaatcccgaccccatggacttctgcaccaaggacctgctgacgacg agctcggagagaatcatctcctacctgcgggacttcaacgaagaccagaagaaagccatc gagacggcctacgccatggtgcggcactcgccctccgtggccaagatctgtctcatccac gggcctcccgggacagggaaatccaagacgatcgtcggcctcttgtaccgcctcctgaca gagacccagaggaggggccgctcggatgagaactccaatgccaaaatcaagcagaaccgg gtgctggtgtgcgcgccctccaatgccgctgtggacgagctcatgaagaagatcatcctc gagttcaaagagaagtgtaaagacaagaagaaccctctgggcaactgtggggatatcaac ctagtgcgtctgggtccagagaagtcaatcaacaccgaggtcttaaaattcagcttggac agccaagtcagccacaggatgaaaagagacttgccttctcacgtccaggacatgcacagg aggaaggagtgcctggaccaccagctggacgagctttcccgccagcgggctctgtgccga ggggcgagggagaaacagagacaagagttggatgatagaattgccaaggtgtccaaagag aggcaggaactggcgtctaaaatcaaagaggtgcaggggcggccccagaaggcgcagagc ctcatcatcctggagtcgcacgtcgtctgctgcacgctgagcacgagcggcgggctgctg ctggaggccgccttccgcggccagggcggcgtgcccttcagctgcgtcatcgtggacgag gccgggcaggcgtgtgaggtggagaccctgacgcccctcatccaccgctgcaacaagctc atcctggtcggagaccccaagcagctcccccccacggtcatctccatgaaggcgcaggag tacggctacgaccagtcgatgatggcccgtttctacaagctgctggaggagaaggtggag cagagcctgctgggccggatgcctgtcgtgcagctgacggtgcagtaccgcatgcacccc gacatctgcctcttcccctccacctacgtctacaacaggagcctgaagaccaacagggcg accgagacggcgcgttgctcgtcagactggcccttccagccctacctcgtgttcgacgtg ggcgacggcgccgagaggcgggacaacgactcatacgtaaacgtccaggaaatcaaactg gtcatggaaataatcaaactcatcaaggagaagcggaaggacgtgaccttccggaacatc ggcgtcatcacccactaccgggcgcagaagaccctgattcagagggacctggacagggag tttgaccggaaaggactggcagaggtggacaccgtggacgcgttccagggccgtcagaaa gactgcatcatcgtgacgtgtgtccgagcgaattccacgcaaggctccatcggcttcctg tccagtctgcagagactgaacgtcgccatcacccgggccaagtacagcctcttcatcctc gggcacctgaggactctgatggacaacccgcactggaaccacctgatccaggacgcgcag cggcgcggcgccatcgtgaagacgtgcgaccgcagctaccggcacgacgcgctgaagatc ctgaagctgaaggccggcacgctgcagcgcagcctcacgcacccgcccgccgccacgccc gagcccgcccggccccagggcggcctccccagcagcaccccggacggcggcctcacctcc acgtcgtccccctacctcacgccccccgactccggtgagtccccggtccccaccaaggac cccgagaaggccccggtgcaggaccgcctccgggacccccggctgctgagaagactgggc gtctccctggaggccagaggggctgtgatgggggcgccccggccccagagcccgcagccc cccccggcctgccccgtgctgggggggctgcaggagctgagcggcctgctgctgtccgca cactgccccctggacaccctgccccccggggagctgagggccgccggtgtcccgcagagg accgagggctgggacaagaggccgctgggggacagcgacagctaccccaagaggaggaag ctcctgtag

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