Sorex araneus (European shrew): 101558115
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Entry
101558115 CDS
T07854
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
sara
Sorex araneus (European shrew)
Pathway
sara00230
Purine metabolism
sara00670
One carbon pool by folate
sara01100
Metabolic pathways
sara01523
Antifolate resistance
Module
sara_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
sara00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101558115 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101558115 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101558115 (GART)
Enzymes [BR:
sara01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
101558115 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
101558115 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
101558115 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
Dala_Dala_lig_C
CPSase_L_D2
ATP-grasp_2
ATP-grasp_3
ATP-grasp_4
RimK
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-GeneID:
101558115
NCBI-ProteinID:
XP_012790882
LinkDB
All DBs
Position
Unknown
AA seq
1022 aa
AA seq
DB search
MAARVLVIGNGGREHALAWKLAQSNHVKQVLVAPGNAGTACDLKISNTAISVSDHNSLAQ
FCKDEKIDLVVVGPEAPLAAGIVGTLTAAGVRCFGPTAEAAQLESSKKFAKEFMDRHGIP
TARWKAFTRPEDACNFVMSANFPALVVKASGLAAGKGVIVAKSREEACKAVQEIMQDKAF
GAAGETIVVEELLTGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDQGPNTGGMGAYCPAP
QVPKSLLLTIENNILQRTVDGMREEAVPYTGVLYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLQSDLYEVIQSTLDGRLATSPPIWLENRTAITVVMASKGYPGDYAKGVEITGLQEA
HALGLQVFQAGTALRGAKVVTNGGRVLTVTSIQEDLISAQQEASRGLTTVAFEGAVYRKD
IGSRAIAFLQQTSKPCTPQGVTNKISGPDIAGGLVLTFSLGSGGALHFRSSPTGCDVNLG
GFAGLCDVKAAGFKDPLLVSGTDGVGTKLRIAQLCNKHDTIGQDLVAMCVNDILAQGAEP
LFFLDYFSCGKLDLRTAEVVIAGIAKACEEAGCALLGGETAEMPDMYPPGEYDLAGFAVG
AVERDQQLPRLDSIAEGDVVIGIASSGLHSNGFSLVRKIVAKSALQYSSPAPSGCGAQTL
GDLLLTPTRIYSRSLLPVLCSGRVKAFAHITGGGLLENIPRVLPSALGVHLDARAWRIPA
IFSWLQREGRISEEEMARTFNCGIGAALVVSEDQAQQIIQELEKQQEEAWVIGKVVACPE
GSPPVTVKHLIEAMDMNSTASGNGALVGNGTLRPDKARVAVLISGTGSNLQALIDSTQEP
RSSAEIVVVISNKAAVAGLEKAERAGIPTRVVSHKSYKTRELFDSAVDQILQEFSVDLVC
LAGFMRILSGHFVQKWNGKLLNIHPSLLPSFKGSNAHEQALAAGVTVTGCTVHFVAEDVD
AGQIILQEAVAVERADTVETLSERVKLAEHKVFPAALQLVASGTVRLGDNGKICWTKEKQ
AS
NT seq
3069 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtccttgtgattggcaatggaggaagagagcacgcactggcttggaaa
cttgcacagtctaaccatgtcaagcaagtgttggttgccccaggaaacgcaggcactgcc
tgtgacttgaagatctcaaacactgccatctcagtaagtgaccacaattccctggctcag
ttctgcaaagatgagaagattgatctggtggtggttggaccagaagcacctctggctgct
ggaattgttgggactctgacagctgcaggagtacgatgcttcggcccaacagcagaagca
gctcaattggagtccagcaaaaagtttgccaaagagtttatggaccgacatggcatccca
actgcacggtggaaagccttcaccagaccggaagatgcctgcaacttcgtcatgagcgca
aacttccctgctttggttgtgaaggccagtggtcttgcagctgggaaaggggtgatcgtt
gccaagagcagagaggaggcctgcaaggctgtgcaagaaattatgcaggataaagccttt
ggagccgctggagaaactattgtcgttgaagagctgcttacaggagaagaggtgtcttgt
ctgtgcttcaccgatgggaagactgtggcccccatgccccccgcccaggatcataagcgg
ctgctggagggggaccagggtcccaacacggggggcatgggcgcctactgcccagctcct
caggttcctaagagcctgttactaacgattgaaaacaacatcctgcagaggacggtggat
gggatgcgtgaggaggccgtgccctacactggtgttctctatgctggtataatgctgacc
aaggatggacccaaagttctggaatttaactgtcgatttggtgatccagaatgtcaagtg
atcctgccacttctgcagagtgacctgtatgaagtgatccagtccaccttagatggccgg
ctggccacgtctccacccatctggctggaaaaccgcaccgccatcactgttgtcatggcg
agcaaaggttatcctggagactacgccaagggtgtggagatcacaggcctccaggaggcc
cacgccttggggctgcaggtgttccaggcgggcaccgccctccggggtgccaaggtggta
acgaacggggggagagtcctcaccgtgacctccatccaggaagatctcatctcggcccag
caggaggccagcagggggctgacaaccgtggcgttcgagggagccgtttacaggaaggac
atcggctctcgggccatagctttcctccagcagaccagtaaaccctgcacaccacaaggt
gtgacaaacaaaatctcggggccagatatagcaggcgggcttgttctaacattctcactc
ggcagtggtggagctcttcactttcggtcttccccaacaggctgtgatgttaatctcgga
ggcttcgctggcctctgtgatgtgaaagcagctggtttcaaggatcctcttctggtcagt
ggaacagacggtgttgggactaaactgaggattgcccagctgtgtaataagcatgacacc
attggtcaagatttggtggccatgtgcgtgaacgatatcctggcccaaggagcggaaccc
ctcttcttccttgattacttttcctgtggaaaacttgacctcaggacagctgaagttgtc
attgctggaatcgccaaagcgtgcgaagaagctgggtgtgctctacttggcggggaaacg
gcagaaatgcccgacatgtatccacccggagagtatgacctcgcgggctttgccgtgggt
gccgtggagcgggaccagcagctcccacgcctggacagcatcgccgaaggggacgtggtg
atcggcatcgcgtcatcaggccttcacagcaacgggttcagcctggtgaggaagatcgtg
gcgaagtctgccctccagtactcctctccagcacccagcggctgcggggcccagacccta
ggggacttgcttctgacgcccaccagaatctacagccgctccctgttacctgtcctatgc
tccggacgcgtcaaggcctttgcccatattaccggtgggggcttgctggagaacatcccc
cgcgtcctcccctcggcactgggagtgcatttagatgcccgggcctggaggatccctgcg
atcttctcctggttgcagagggaaggacgcatctcagaggaggagatggccaggaccttt
aactgtggcatcggggctgccctcgtggtgtccgaggaccaggcacagcagatcattcag
gagcttgagaagcagcaggaagaagcctgggtgatcggcaaggtggtggcctgtccggaa
ggttctcctcctgtgacggtcaagcacctgattgaagccatggacatgaacagcactgca
tcaggaaatggggccttggtggggaatggcaccctgagacctgacaaggccagagtggct
gtcctgatctcggggacagggtcaaacctccaagctctcatagacagtacccaggagcca
aggagctctgcggaaatcgtcgtggtcatctccaacaaagccgccgtggccgggttagag
aaagcggaaagagccgggattcccacccgagtagtcagtcataaatcctataaaacacgg
gaactatttgacagtgcggtcgaccaaatcctccaagaattctctgtagatttagtctgt
cttgctggattcatgagaattttatctggccactttgtccagaaatggaacgggaaattg
ctcaacatccacccatccctgctcccatctttcaagggctcgaatgcccatgagcaagcg
ctggcggccggagtcacagtcaccggctgtacggtgcactttgtcgcggaagacgtagat
gccgggcagatcatcttacaggaagctgtggccgtggagagagcggacacagtggagacg
ctgtcggaaagagtgaagctagcagaacacaaagtattccctgcagccctgcagctggtg
gccagcgggacggtgcggctcggggacaacggcaagatctgctggacgaaggagaagcaa
gcctcctga
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