Sorex araneus (European shrew): 101558377 Help Entry 101558377         CDS       T07854                                  Symbol PKLR Name (RefSeq) pyruvate kinase PKLR   KO K12406   pyruvate kinase isozymes R/L [EC:2.7.1.40] Organism sara  Sorex araneus (European shrew) Pathway sara00010   Glycolysis / Gluconeogenesis sara00620   Pyruvate metabolism sara01100   Metabolic pathways sara01200   Carbon metabolism sara01230   Biosynthesis of amino acids sara04910   Insulin signaling pathway sara04930   Type II diabetes mellitus sara04932   Non-alcoholic fatty liver disease sara04950   Maturity onset diabetes of the young Module sara_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate sara_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:sara00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     101558377 (PKLR)    00620 Pyruvate metabolism     101558377 (PKLR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101558377 (PKLR)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101558377 (PKLR)    04950 Maturity onset diabetes of the young     101558377 (PKLR)    04932 Non-alcoholic fatty liver disease     101558377 (PKLR)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:sara04147]     101558377 (PKLR) Enzymes [BR:sara01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      101558377 (PKLR) Exosome [BR:sara04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    101558377 (PKLR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK PK_C IMPDH HpcH_HpaI Motif Other DBs NCBI-GeneID:  101558377 NCBI-ProteinID:  XP_004619343 LinkDB All DBs Position Unknown AA seq 574 aa AA seqDB search MSTQENTQHQQLWSWVSKSQKDLAKSILIGAPGGPAGYLRRASVAQLTQELGTAFFQRQQ LPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFS HGSHEYHAQSIANVREAVESLATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVELVKG SSVLVTVDPEFRTRGDAKTVWVDYPNIVRVVPVGGHIYIDDGLISLAVRKIGSRGLETEV ENGGTLGSRKGVNLPGALVDLPGLSEQDARDLQFGVEHGVDIIFASFVRKASDVVAVRSA LGPEGQGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC NLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVQM QHAIAREAEAAVYHRQLFEELRRAAPLSRDLAEVTAIGAVEAAFKCCAAAIIVLTKTGRS AQLLSRYRPRAAVIAITRSAQAARQAHLCRGVFPLLYRDPPEPVWADDVDRRVQFGIDSG KLRGFLHPGDLVIVVTGWRPGAGYTNIMRVLNVS NT seq 1725 nt NT seq  +upstreamnt  +downstreamnt atgtcgacccaggagaacacacaacaccagcagctctggtcatgggtctctaagtcccaa aaggacttagcaaagtccatccttattggggctccaggagggccagcgggatacctgagg cgggccagcgtggcacagctgacccaggagctgggcacggcattcttccagcggcaacag ttgccagctgccatggcagacacctttctggagcacctgtgcctgctggacatcgactct gagcctgtggccgctcgcagcaccagcatcattgcgacaatcgggcccgcatcgcgctcg gtggagcgcctcaaggagatgatcaaggccggcatgaacatcgcgcggctcaacttctcc catggctcccacgagtaccacgctcagtccatcgccaacgtccgggaggcggtggagagc ctggccacctccccgctcagctaccgcccggtggccatcgctctggacaccaagggaccg gagattcgcaccggggtcctgcaggggggccctgagtcggaagtggagctggtgaagggc tcctcggtgctggtgacggtggacccggagttccgaacgcggggggacgcgaagaccgtg tgggtggactaccctaatatcgtccgggtggtgccggtggggggccacatctacatcgac gacgggctcatctccctcgcggtcaggaaaatcggctccagagggctggagactgaagtg gagaacggaggcaccctaggcagccggaagggggtgaacctgccaggagccctggtagat cttcctgggctgtctgagcaagatgcccgggaccttcagttcggggtggagcatggcgtt gacatcatctttgcgtcctttgtgcggaaagccagtgatgtggttgctgtccggtctgcc ctggggcctgaaggtcagggcatcaagatcattagcaaaatcgaaaaccacgaaggtgtg aagagatttgatgaaatcctggaggtgagcgacggcatcatggtggcccgcggggacctg ggcattgagatcccagccgagaaggtctttctggctcagaagatgatgatcggtcgttgc aacttggcgggcaagcccgttgtctgtgccacacagatgctggagagcatgatcaccaaa ccacggcccactcgagcagagaccagcgacgtggccaacgcagtgctcgatggggcggac tgcatcatgctctcgggtgagaccgccaagggcagctttcctgtggaggctgttcagatg cagcacgcgatcgcacgtgaggccgaggccgctgtgtaccaccggcagctgtttgaggaa ctgcgccgggcagccccgctgagccgggacctcgccgaggtcactgccattggtgctgtg gaggctgccttcaagtgctgcgccgcagccataattgtgctgaccaaaactggccgctcc gcccagcttctgtcccggtaccgcccccgggcggccgtcattgccatcacacgctccgcc caggcggcccgccaggcacacctgtgtcgaggagtcttccccttgctctaccgtgatcct ccggagcccgtgtgggcggacgacgtggaccgccgggtgcagttcggcattgacagcgga aagctgcgtggcttccttcacccgggagacctggtgatcgtggtgactggctggcggccc ggcgctggctacaccaacatcatgcgagtactgaatgtgtcctga

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