Sorex araneus (European shrew): 101559239 Help Entry 101559239         CDS       T07854                                  Symbol NOS1 Name (RefSeq) nitric oxide synthase, brain   KO K13240   nitric-oxide synthase, brain [EC:1.14.13.39] Organism sara  Sorex araneus (European shrew) Pathway sara00220   Arginine biosynthesis sara00330   Arginine and proline metabolism sara01100   Metabolic pathways sara04020   Calcium signaling pathway sara04081   Hormone signaling sara04145   Phagosome sara04371   Apelin signaling pathway sara04713   Circadian entrainment sara04730   Long-term depression sara04926   Relaxin signaling pathway sara04970   Salivary secretion sara05010   Alzheimer disease sara05014   Amyotrophic lateral sclerosis sara05022   Pathways of neurodegeneration - multiple diseases sara05410   Hypertrophic cardiomyopathy sara05412   Arrhythmogenic right ventricular cardiomyopathy sara05414   Dilated cardiomyopathy sara05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:sara00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     101559239 (NOS1)    00330 Arginine and proline metabolism     101559239 (NOS1)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     101559239 (NOS1)    04020 Calcium signaling pathway     101559239 (NOS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     101559239 (NOS1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     101559239 (NOS1)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     101559239 (NOS1)   09154 Digestive system    04970 Salivary secretion     101559239 (NOS1)   09156 Nervous system    04730 Long-term depression     101559239 (NOS1)   09159 Environmental adaptation    04713 Circadian entrainment     101559239 (NOS1)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     101559239 (NOS1)    05014 Amyotrophic lateral sclerosis     101559239 (NOS1)    05022 Pathways of neurodegeneration - multiple diseases     101559239 (NOS1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     101559239 (NOS1)    05412 Arrhythmogenic right ventricular cardiomyopathy     101559239 (NOS1)    05414 Dilated cardiomyopathy     101559239 (NOS1)    05416 Viral myocarditis     101559239 (NOS1) Enzymes [BR:sara01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      101559239 (NOS1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 PDZ PDZ_6 PDZ_2 PGDYG Motif Other DBs NCBI-GeneID:  101559239 NCBI-ProteinID:  XP_012788768 LinkDB All DBs Position Unknown AA seq 1376 aa AA seqDB search MENPGLSVQQIQPNVISVRLFKRRVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLVQA GDIILAANGQPLVDLSYDNALEVLRGIASETHAVLILRGPEGFTTHLETTFTGDGTPKTI RVTRPLGPAPAAAIDLSSPPAALQRCPLRGDLDSKAHRALPLSVDNDRVFNDLWGKDSAP VVLNNPYSEKEQPPASGKHSPTKNGSPTKCPRFLKVKNWETDVVLTDTLHLKSTVETGCS EHICMGSVMLPSQHVRRPEDVRTKAQLFPLAKEFIDQYYSSIKRFGSKAHMERLEEVNKE IHATSTYQLKDTELIYGAKHAWRNAARCVGRIQWSKLQVFDARDCTTAHGMFNYICNHIK YATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDSSILGDPASVELTEICMQ QGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFQELGLKWYGLPAV SNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDSSRYNILEEVAKKMNLDMRKTSSLWKD QALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSI TPVFHQEMLNYRLTPSFEYQPDPWNTHVWKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQ AMAKRVKATILYATETGKSQAYAKTLCEIFKHAFDAKVMSMEEYDIVHLEHETLVLVVTS TFGNGDPPENGEKFGCALMEMRHPNSVHEERKNPEPLHFFPRQGPALPRGDPGARGLALA RDRQHRSYKVRFNSVSSYSDSRKSSGDGAELRDNFESTGPLANVRFSVFGLGSRAYPHFC AFGHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKA NNSLISNDRSWKRNKFRLTYVAEAPELTQGLSGVHKKRVSAARVLSRQNLQSAQSSRSTI FVRLHTNGNPELQYQPGDHLGVFPGNHDDLVSALIARLEDAPPPDQVLKVELLEERNTAL GVISNWTDEARLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSESEKQRLLVLSKGLQ EYEEWKWGKNPTVVEALEEFPSVQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVA VLSYRTRDGQGPVHHGVCSSWLNRIPPGESVPCFVRGAPSFRLPRNPHAPCFLVGPGTGV APFRSFWQQRQFDIQHKGLSPCPMVLVFGCRQSEMDHIYKEEALQAKGKGVFRELYTAYS REPDRPKKYVQDILQEQLAEPVYRALKEQGGHIYVCGDVTMAADVLKAVQRILAQQGRLS AEDAGVFVSRLRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDMDEVFSS NT seq 4131 nt NT seq  +upstreamnt  +downstreamnt atggagaaccccggcctcagcgtgcagcagatccagcccaatgtcatctccgtccgcctg ttcaagcgccgggtgggcggcctgggcttcctggtgaaggagcgcgtgagcaagccgccc gtgatcatctcggacctgatccgcgggggcgcggccgagcagagcggcctggtgcaggcc ggggacatcatcctggcggccaacgggcagccgctggtggacctgagctacgacaacgcc ctggaggtgctccgcggcatcgcctccgagacccacgcggtgctcatcctgcggggcccc gagggcttcaccacgcacctggagaccaccttcacgggcgacgggacccccaagaccatc cgcgtgacccggcccctgggccccgcccccgccgcggccatcgacctgtcctcgccgccc gcggccctgcagcgctgcccgctgcgtggggacctggacagcaaggcccacagggccctg cccctcagcgtggacaacgaccgagtcttcaacgacctctggggaaaggacagcgcgccg gtggtgctcaacaacccgtactcggaaaaggagcagccccccgcctcggggaagcactcc cccaccaagaatggcagccccaccaagtgcccccgcttcctcaaggtcaagaactgggag acggacgtggtcctcaccgacaccctgcacctgaaaagcacagtggagacgggctgcagc gagcacatctgcatgggctccgtcatgctgccgtcccagcacgtccgccggcccgaagac gtccgcaccaaagcacagctcttccccctggccaaggagttcatcgaccagtactactcg tccattaagaggtttggctccaaggcccacatggagaggctggaggaggtgaacaaggag atccacgccaccagcacctaccagctgaaggacacggagctcatctacggagccaagcac gcctggcggaatgccgcccgctgcgtgggcaggatccagtggtccaagctgcaggtgttc gatgcccgtgactgcaccacggcccacggcatgttcaactacatctgcaaccacatcaag tacgccaccaacaaagggaacctcaggtctgccatcaccatcttcccccagaggactgac ggcaagcatgacttccgtgtctggaactcccagctcatccgctacgccggctacaagcag cccgacagctccatcctgggggacccggccagtgtggagctcactgagatctgcatgcag caaggctggaaaccaccacgcggccgctttgacgtcctgccgctcctgctccaggccaac ggcaacgaccccgagctcttccagatcccgccagagctggtgctggaagtgcccatccgg caccccaaattcgactggttccaggagcttggcctgaagtggtacgggctccccgccgtg tccaacatgctgctggagatcggcggcctggagttcagcgcctgcccgttcagcggctgg tacatgggcacggagatcggcgtgcgggactactgcgacagctcccgctacaacatcctg gaggaagtggccaagaagatgaacctggacatgaggaagacgtcgtcgctgtggaaggac caggcgctggtggagatcaacatcgccgttctctacagcttccagagcgacaaagtgacc atcgtggaccaccactcggccaccgagtccttcatcaaacacatggagaacgagtaccgc tgccgggggggctgcccggccgactgggtgtggatcgtgccccccatgtccggcagcatc acccccgtcttccaccaggagatgctcaactaccggctcacgccctccttcgagtaccag cctgacccttggaacacccacgtctggaaaggcaccaacgggacccccaccaaaaggcgc gccatcggctttaagaagctggcggaagccgtcaagttctcggccaaactgatgggacag gcgatggccaagcgggtcaaggccaccatcctttacgccacggagacgggcaagtcgcag gcctatgccaagactttgtgtgagatcttcaaacacgccttcgatgccaaggtcatgtcc atggaggagtatgacatcgtacacctggaacacgagacgctggtcctggtggtcaccagc acctttggcaatggagaccccccggagaatggggagaaattcggctgtgctctgatggag atgagacaccccaactccgtgcatgaggagaggaagaacccggaacccttgcatttcttt ccccgtcaaggccctgccctcccgcgaggcgacccgggagcccggggtctggccctagcc cgggaccgccagcacaggagctacaaggtccgcttcaacagcgtgtcctcatactccgac tcccggaagtcgtcaggcgacggggccgagctcagagacaactttgagagcaccgggccg ctggccaacgtgaggttctccgtgttcggcctgggctccagggcctaccctcacttctgc gccttcggccacgccgtggacacgctgctggaggagctgggcggggagcggatcctgaag atgcgggagggcgacgagctgtgtgggcaggaggaggccttcaggacctgggccaagaag gtcttcaaggcagcctgtgatgtgttctgtgtgggcgacgatgtgaacatcgagaaagcc aacaactctctcatcagcaatgaccgcagctggaagagaaacaagttccgcctcacctat gtggctgaagctccggagctgacccaaggtctgtccggcgtccacaagaagcgggtctca gcggcgcgagtgctcagccgtcagaacctccagagtgcccagtccagccgctccaccatc ttcgtgcgcctccacaccaacgggaaccccgagctgcagtaccagcccggcgaccacctg ggcgtcttcccgggcaaccacgacgacctggtgtccgccctcatcgcgcggctggaggac gcgccgccgcccgaccaggtgctgaaggtggagcttctggaggagcggaacacggcgctg ggagtcatcagcaactggaccgacgaggcccgcctcccgccctgcaccatcttccaggcc ttcaagtactacctggacatcaccacgccccccacgccgctgcagctgcagcagttcgcc tccctggccaccagcgagagcgagaagcagcggctgctggtcctcagcaagggcctgcag gagtacgaggagtggaagtggggcaagaaccccacggtggtggaggcgctggaggagttc ccgtccgtgcagatgcccgccacgctgctgctcacgcagctgtccctgctgcagccccgc tactactccatcagctcgtccccggacatgtaccccgacgaggtgcacctcaccgtggcc gtgctctcctaccgcacccgagacggacaaggccccgtccaccatggcgtgtgctcctcc tggctcaatcgcatcccgcccggcgagagcgtgccctgcttcgtgcgcggggcgcccagc ttccgcctgccccggaacccccacgcgccctgcttcctggtgggccccggcaccggcgtc gccccgttccggagtttctggcagcagcgacagtttgacatccagcacaaaggcctgagc ccctgccccatggtcctggtcttcgggtgccggcagtccgagatggaccacatctacaag gaggaggccctgcaggccaagggcaagggcgtcttccgagagctgtacaccgcctactcc cgggagcccgacaggcccaagaaatacgtgcaggacatcctgcaggagcagctggcggag cccgtgtaccgcgcactcaaggagcagggcggccacatctacgtgtgcggggacgtcacc atggccgccgacgtgctcaaggccgtgcagcgcatcctggcccagcagggccggctctcg gccgaggacgcgggcgtgtttgtcagccgcctgcgggatgacaaccgataccacgaggat attttcggggtcaccctgcggacgtacgaggtgaccaaccgccttagatccgaatccatt gccttcatcgaggagagcaaaaaggacatggatgaggtgttcagttcctaa

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