Streptomyces armeniacus: DVA86_11510
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Entry
DVA86_11510 CDS
T10140
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sarm Streptomyces armeniacus
Pathway
sarm00290
Valine, leucine and isoleucine biosynthesis
sarm00660
C5-Branched dibasic acid metabolism
sarm01100
Metabolic pathways
sarm01110
Biosynthesis of secondary metabolites
sarm01210
2-Oxocarboxylic acid metabolism
sarm01230
Biosynthesis of amino acids
Module
sarm_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
Enzymes [BR:
sarm01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
DVA86_11510 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
DVA86_11510 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
AXK33179
UniProt:
A0A345XNG3
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All DBs
Position
2620357..2621799
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AA seq
480 aa
AA seq
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MGRTLAEKVWDDHVVRRVEGEPDLLFIDLHLLHEVTSPQAFDGLRKAGRRVRRTDLTLAT
EDHNTPTLDIDKPIADPVSRVQLETLRKNCADFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLAPFRTMAITVNGELPADVTA
KDLILAIIAKIGTGGGQGYVLEYRGEAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLEGRDHAPQGADWDEAVAYWRTLRTDDDAVFDHEVVIEADELAPFVTWGTNPGQGAPL
SASVPDPAGFADPGERLAAEKALEYMGLTAGKPLREITVDTVFVGSCTNGRIEDLRSAAA
VVEGRQIADGVRMLVVPGSVRVSLQAVEEGLDKVFTEAGAEWRHAGCSMCLGMNPDQLKP
QERAASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGRLASPADLPSRPGNPSSREPVGV
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
atgggacggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgtggaaggt
gagcccgacctcctctttatcgatctgcatctcctgcacgaggtgaccagcccgcaggcg
ttcgacggtctccgcaaggcgggccggcgcgtgcgccgtacggatctcacgctcgcgacc
gaggaccacaacaccccgacgctggacatcgacaagcccatcgcggaccccgtctcccgt
gtccagctggagacgctccgtaagaactgcgcggacttcggcgtacggctgcatccgctg
ggcgacgtcgagcagggcgtcgtgcacgtcgtcgggccgcagctggggctgacccagccc
ggcaccaccgtggtctgcggtgacagccacacctccacgcacggcgcgttcggcgcgctc
gcgttcggcatcggcaccagccaggtcgagcacgtgctggcgacgcagacgctgccgctg
gcaccgttccgcaccatggcgatcacggtcaacggcgagctgcccgcggacgtcaccgcc
aaggacctgatcctggcgatcatcgcgaagatcggcaccggcggcggtcagggttacgtg
ctggagtaccgcggcgaggccatcgagaagctgtcgatggaagcccggatgaccatctgc
aacatgtcgatcgaggcgggcgcgcgggccgggatgatcgcccccgacgagacgaccttc
gcgtatctcgagggtcgcgaccacgccccgcagggcgccgactgggacgaggccgtcgcg
tactggcgcacgctgcgcaccgacgacgacgccgtcttcgaccacgaggtggtcatcgag
gccgacgagctggccccgttcgtcacctggggcaccaacccgggccagggcgcgccgctg
tccgcgtccgtgcccgacccggccggcttcgccgacccgggtgagcggctggcggcggag
aaggccctggagtacatggggttgaccgcgggcaagccgctgcgcgagatcaccgtcgac
acggtgttcgtcggctcctgcaccaacggacgcatcgaggacctgcggtccgcagcggcc
gtcgtcgagggccgccagatcgcggacggcgtacggatgctggtggtacccggctccgta
cgggtctcgctgcaggccgtcgaggaagggctggacaaggtgttcaccgaggccggcgcc
gagtggcggcacgcgggctgttcgatgtgtctgggcatgaaccccgaccagctcaagccg
caggagcgcgccgcctccacctccaaccgcaacttcgagggcaggcagggcaagggcggc
cgtacgcacctcgtctccccccaggtcgccgcggccaccgcggtgctggggcggctggcc
tcgccggccgatctgccgtcccgtcccggaaatccgagcagccgcgagcccgtgggggtc
tga
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