Streptomyces armeniacus: DVA86_17445
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Entry
DVA86_17445 CDS
T10140
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sarm Streptomyces armeniacus
Pathway
sarm00790
Folate biosynthesis
sarm01100
Metabolic pathways
sarm01240
Biosynthesis of cofactors
Brite
Enzymes [BR:
sarm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
DVA86_17445
6.3.2.17 tetrahydrofolate synthase
DVA86_17445
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AXK34170
UniProt:
A0A345XRA4
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Position
4012005..4013555
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AA seq
516 aa
AA seq
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MSEQPQEPEPEPDDASGEATGDAPDEFEEIVDAETLRDPDLAVIEAGSRTLRAQAGPPPT
GLAPGRPEDPEADRALRAVEEELATRWAETKLEPSRVRITALLDVLGEPQRTYPSIHITG
TNGKTSTARMIEVLLAGFELRTGRYSSPHVQSITERISVDGAPLSAERFVETYDDIKPFV
EMVDAQQSYRLSFFEVLTGMAFAAFADAPVDVAVVEVGMGGTWDATNVMDASVAVLTPIS
LDHTDRLGDTPEEIAGEKAGIVKRDATVVLAQQPVEAASVVLKKAVEVDATVAREGMEFG
VVSREVAVGGQLLTLRGLGGEYPDIFLPMHGAHMAHNASVALAAVEAFFGIGSEPARTLD
IDTIRQAFAAAATPGRLELVRSSPSVLLDAAHNPAGAQATAAAVTEAFGFSRLIGVVGPS
GDKDVRGLLEAFEPVFTEVVVTRNTTHRAMDVDELAALAVEVFGEDRVQVEPRLDDAVEA
AITLAEEEGEYAAAGVLVTGSVITVGEARLLLGRGR
NT seq
1551 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgagcagccccaggaacccgagcccgagcctgacgacgcctccggtgaggcgacc
ggcgatgcccccgacgagttcgaggagatcgtggacgcggaaacccttcgcgaccccgat
ctcgccgtgatcgaggccggcagccgtaccctccgcgcgcaggcgggccccccgccgacc
gggctcgctccggggcgcccggaggacccggaggcggaccgggcgctgcgcgccgtggag
gaggagctcgccacccgctgggccgagaccaagctcgagccgtcccgggtgcggatcacc
gcgctgctggacgtcctgggcgagccgcagcgcacgtacccgtcgatccacatcaccggc
accaacggcaagaccagcaccgcccgcatgatcgaggtgctgctcgccggcttcgagctg
cgcaccggccggtacagcagcccgcacgtgcagtcgatcaccgagcggatcagcgtcgac
ggtgccccgctctccgccgagcgcttcgtcgaaacgtacgacgacatcaagccgttcgtg
gagatggtcgacgcccagcagtcgtaccggctgtcgttcttcgaggtgctcaccggcatg
gccttcgccgcgttcgccgacgccccggtcgacgtcgccgtggtcgaggtcggcatgggc
ggcacctgggacgcgacgaacgtcatggacgcgtccgtcgccgtcctgacccccatctcc
ctggaccacaccgaccggctcggcgacaccccggaggagatcgcgggggagaaggccggg
atcgtgaagcgggacgcgacggtggtgctcgcgcagcagcccgtggaggccgcgtccgtg
gtgctcaagaaggccgtcgaggtggacgccacggtggcccgcgagggcatggagttcggg
gtggtctcgcgtgaggtcgcggtcggcgggcagctgctgacgctgcgcggcctgggcggc
gagtatccggacatcttcctgccgatgcacggcgcgcacatggcgcacaacgcctcggtc
gcgctcgccgccgtcgaggcgttcttcggcatcggctcggagcccgcccgcacgctcgac
atcgacaccatccggcaggcgttcgcggcggcggccactccgggccggctggagctcgta
cggtcctcgccgtccgttctgctggacgccgcgcacaacccggcgggcgcgcaggcgacg
gcggcggcggtgacggaggcgttcggcttcagcaggctgatcggggtggtcgggccgagc
ggggacaaggacgtacgggggctgctggaggcgttcgagccggtgttcacggaggtcgtg
gtcacccggaacaccacgcaccgcgcgatggacgtggacgagctcgcggcgctcgccgtc
gaggtgttcggggaggaccgggtgcaggtggagccgcggctggacgacgcggtggaggcg
gcgatcacgctggcggaggaggagggcgagtacgccgcggccggcgtgctggtcaccggc
tccgtcatcacggtcggcgaggcgcggctgctgctgggaaggggccgctag
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