Salmo salar (Atlantic salmon): 106577062 Help Entry 106577062         CDS       T04363                                  Name (RefSeq) ryanodine receptor 2-like   KO K04962   ryanodine receptor 2 Organism sasa  Salmo salar (Atlantic salmon) Pathway sasa04020   Calcium signaling pathway sasa04260   Cardiac muscle contraction sasa04261   Adrenergic signaling in cardiomyocytes sasa04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:sasa00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     106577062    04020 Calcium signaling pathway     106577062  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     106577062    04261 Adrenergic signaling in cardiomyocytes     106577062  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:sasa04040]     106577062    04990 Domain-containing proteins not elsewhere classified [BR:sasa04990]     106577062 Ion channels [BR:sasa04040]  Voltage-gated cation channels   Ryanodine receptor    106577062 Domain-containing proteins not elsewhere classified [BR:sasa04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    106577062 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 MIR SPRY Ins145_P3_rec RIH_assoc Ion_trans EF-hand_6 EF-hand_7 EF-hand_1 EF-hand_5 EF-hand_8 Motif Other DBs NCBI-GeneID:  106577062 NCBI-ProteinID:  XP_014010249 UniProt:  A0A1S3N474 LinkDB All DBs Position ssa18:21562792..21639029 Genome browser AA seq 4978 aa AA seqDB search MAESGESEDEIQFLRTNDEVVLQCIFTSQQEHLKLCLAAEGFGCRLCCLESTSNCKNVPP DLSVCSFVLAQCLSVRALQEMLANREDQAAGAGQGGGHRTLLYGHAVLLIHSYSRMYLCC LSTSQSSTDKLAFDVGLQDDKTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYL HLSYGSVIDNTSESGSLIVDAAFQQTLWRVAPICSGSGVAQGYLKGGDTLRLLHGHTDEC LTVPSTDQGEELRKMVHYEGGAVSSHARSLWRLEILRVAWSSSHTRWGQPFRLRHVTTGR YLSLTEERGLHLVDRERADVKSTSFCFRPSKEKLECGPKKDTDGMGASEIKYGDSLCYVQ HVDSGLWLTYQAIDAKCARLGAVQRKAIMHNEGHMDDGLSLSRSQWEESHTARLIRSTVL LFTGFIRRLDGLSQQANIPSFNLPLEIVALSLQDLIGYFQPPGEGLGHEARQNSVRALKN RQNLFQEEGVIALVLDCIDRLHLYSSASHFAAAAGKEAGDDWENILNSFYELLAVLIRGN RRNCAQFSGSLDWLVSRLERLEASTGVLEVLHCVLVESPETLNFIREGHIKSIISLLDKH GRNHKVLDVLCSLCVCHGMAVRSNQHLICDNLLPERDLLLQTRLVNQVTSMRPNIFLALG DDSAQHRRWYYEMTVDQVEPFLTAEPTHLRVGWANKEGYNPYLTGGEAWGGNGVGDDLSS YGFDGLYLWSGCVGRRVSSPYHHLLREDDVVSCCIDLVATCISFRVNGQPVQGMLENFNT DGLLFPVVSFSAGVKVRFLLGGRHGEFHFLPPPGFAPCSEALLPRVKLRVEPCQDFTQEQ YLLGPTVPLTPATFTPSPVDISQVVLPVQLEHIRERLAENTHELWVMDKIDLGWTNGAVR DDSKKQDPCLVEFSRLPEQERNHSLQMSQDTLRTLIALGLHIGLADGRADEGVRYLRLST KYEMPSGYRPAPVDLSHIILSPAQEAVVELLAENDHNVWARDRIRQGWTYSSHQDVKAKR SPHLVPYSLLDERSRQSGRDGVREAVCTLLCYGYSLEPLDQDRGVMPDPCHTAAEKFRVF RADKSYAVTRGKWYFEFEAVTAGDMRVGWARPHCTPNGELGSDMQAFVFDGSKAQWCHQG GEPLGRPWQSGDVVGCMVDMGECTMMVTLNGEVLLNDRGSELAAKDFDINQGFLPVCSLG VNQKARLNLGRDVASLCYFTVCGLLEGYKPFAVNMARDPALWMSWRQPQFIPVQTDHDSI QVTRITGSTESPPCLKVTQRSLGPQSCGSDMGFYRLSMPIECAEAFSRPVGATLPISSSV STARKDLQEFEVDSDFEMLLKSAHVYTGSRDELNHKDYSHDKTSKLKQRFMLKKSKPELN KSHSSARLLQEVHADKDDYDHLAQSTTYYYSVRVLPGQDPSTVWVGWVTSDFHQHQLTFD LEKIRTVTVTLGDDMGKVHESVKRSNCYMVCAGESTGLGQSRRSAGLAIGCLIDTTTGLL TFSSNGMELGTFFQVEPSTRLFPAVFAKANSSNVFQFELGRVKNMLPLSAGLFRSQRRNA MPQCPPRLQVQVLSPILWTRVPDHTLRVQAAHPDDRLGWRVQCLEPLQVMTLLIPEENRC VDILELSELGDLLSFHHHTLLLYSALCALGNTRVGHALCSHLDQSQLLYAIQSPRLPGPL RSAFYHLLGQVHLSTHATARLAMNHEYIVPMTEQTRAITLYPSPRTSRSPQWVPRMGLST SLRPRMHFTSPCFIRGDGMGVNGDTCGDGVVATGEGIHIDSPEIPLELLKDLTGKMLTEA VWAVGQGVRDPEGGSIELLLVPLIRLFHTLLVMGLFGDEDLGKVLTLIEPGVFSRPAECS PEEAEEEQEEEEQEDENVPDSDRESVMEREGDKRRTIPKLPTKGLLQMKLPEAVKLEICH LFQYLCDCQVRHRVEAVVAFSDTFVGYLQENQHFRYNEVIQALHMSAALTARKTKEFRSP PQEQINMLLGFREEQGDCPCPEDIREQLLDFHQDLMTHCGIEVDHDTEVVEDSNRSIKDR LFSLVGRVIGLKRRSADPEEEDRAQNTMTLQQLISDTVVRWAQECVIENPALVRAMFSLL HRQYEGLGGQMGTPLHKAYTISQVSVEDTMALLASLVQIRSLLSVRMGKEEERLMIRGLG DIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGEGETKEITFPKMVAHCCRFLCYFCRIS RHNQGSMFEHLSYLLDNSSVGLASPSMRGATPLDVAAASVMDNNELALALREPDLEKVVQ YLAGCGLQSCRMLVSKGYPDIGWNPVEGERYLDFLRFAVFCNGESVEENAYLVVRLLIRR PECFGPALRGEGGDGLLAAMEEAIRISEDLSMDGPSTTYESNRTLNVLQDEEDDIIHMGH SIMTFYSALIDLLGRCAPEMHLIHAGKGEAIRIRAILRSLIPIQDLEGVIGIPFQIPSLA KDGTVVEPDPSTVFCPDHKAAMVLFLDRVYGIEDQNFLLHLLEVGFLPDLQAAASLDTTD LSATDMALALNRYLCTAVLPLLTKCSSLFSGTEGQGPLVDALLQAVYRLSRALSLTKAQR DAIEDCMLAICSKLRPSMMQPLLRRLVFDVPLLTNHTKIPLKLLTNHYEQSWKYYCLIGG LGHLGSASEEELHLSRKLFWGVFNALSRKHYDAELSRLALQCLAAAAGALPPDHMDPGCV AWMERHPSMDAQGHFDPQPVDTSNVSVPEKLEFLVNKYAEHTHEKWSMDKFANGWVHGEL CEKTKVHPLLKPYRALAERDKEAYRWSVKETVRSMLAFGWTIERTKEGDGLGLLTCSRRI SQAGQLSFEGASTFTPKPMDMSSVTLSWDQCSVTELLAENYHNTWSRKKKQEVDAKGGGG HSTLVPYDTLPTKEKAKLREKAQEVLKFFQLNGYTVWRDRKAAEMDSPAIANRFAYTFLQ QLLSYTEEAQEYMQELELMQARGPIPIVEAPHQQQIDFFSKVALPLLEQYLKNHRLYFLS TAARSRGNGGQASNKEKEMVTSLFCKLGALVRQRISLFGSDAPSIVSCLLILAQSLDVRT LMKTAPESARVSLRSFFEAAAVDLEMTVENLSMTQSWTQSREVAQILDYTNTALLPTLTS IFEHLSHNQYGEDLLVDSVQVSCYKILNSLHSLGISKSFYVEGQRPSAGACLAALSGAFP VCFLEPALNEDNPYSIYNTMSPREREDVGVPDEVEEVCPLLPSLQQLLGEVEELAGAGSG ARQAQYSHVTEITLPLLCSYVSRWWQHGPEGQLESPVCTSLTSQHASTLLGNILRIIHNH LGTGQGDWMKRLAVFSQPIICQAHPQLLRSHFLPLMEKLKKRAESVLQEEEQIKAEGRAD ASEAELQIQEKFIVLVRDLYAFYPVLIPFVDYNRASWLREPSHEAEKMFGMVAEIFIFWT KSHNFKWEEQNYVVQNEINNMAFLVNNNNHKMSKVSDQERRKMKRKGDRYSTQTSLIVAS LKRLLPVGLSVCSPAVRGLITLAKSRFTQKDTEDEIRESIHNGLLRLQSKQEAPGARWQD VLFRDFPGSTRDTSDPLRTVERVLDIACVLYHLDQVEHPQRKKTVWHKVLSKQRKRAVVA CLRMAPLYNLPRHRAVNLFLQGYDKSWISAEEHSFEEKLVDDLARAGKQERSEREEEGAG EDDDKQIDPLLQLITLFSRSALTERSKLGDDSLYMSYAAIMAKSCCGEEDEEVKSFEEKE MEKQKLLYQQARLHDRGAAQMVLQTISASKGDMGSMVASTLKLGISILNGGNTTVQQKML DYLKEKRDVGFFQSVAGLMQSCSVLDLNAFERQNKAEGLGMVIEESSGEKVMPDEKLTCD LFRFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVI DEHGQRNFSKAISVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKL SQDSSQIELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSSNVEMILKFFD MFLKLKDLTSSDAFKEYDHDGKGRISKKDFQKAMEAYKRYSQSETQFLLSCTETDESELL DYEAFVDRFHEPAKDIGFNIAVLLTNLSEHMPHDSRLGTFLQLAECVLSYFQPYLGRIEI LGSGKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGDGKEKMEMFVNFCEDTIF EMQLAAQISGTDTGERTAGKEAEEEEEKDRGKNDEELERSKMGFFSMSTIWLIVFALPYG LMMLMSMLSVKNLKKHIKKTTLRDVVMVFASFFQAMIMGLVHFVCSVVRFFLYVLYIVFV SGGLIEGAKKIRVFDLFGGILDPTLDEVTGGSGGYRERRYSTRSSSRDELRVLGQSTVSS SDTNVLSDIFGLRVRREGGQYRLMTHDLTASLTDLFNTATGQQSPAEPNGKDQVEGAREG DSKEGEEKNSELEKAEREDSEKEAKAKRRVRICSSKPEEPEPQESAFWEMITTHQKRLLN YFARNFYNMRMLALFVAFSINFILLFYKVSSSSSVSEEEEKVAVLYDSSGGMDEEDPLVN DNTSGSMQFVLEESTGYMEPSLRFLSVAHTLISFCCIIGYYCLKVPLVIFKREKDVARKM EFDGLYVTEQPPDEDIKGQWDRLVITTQSFPSNYWDKFVKRKVMDKYGKFYGCDRISELL GLDKAALDFSSEGQERRRPRREGAWTALLNSIDVKYQVWKLGVVFTDNSFLYLAWYMTMS VLGHYNNFFFAAHLLDIAMGFKTLRTILTSVTHNGKQLVLTLGLLAVVVYLYTVVAFNFF RKFYNKSEDGVALDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEFEVVRIIFDIT FFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYLDNVPHGFETHT LQEHNLANYLFFVMYLINKDETEHTGQESYVWKMYQERCWEFFPVGDCFRKQYEDQLC NT seq 14937 nt NT seq  +upstreamnt  +downstreamnt atggctgaatcaggagaaagcgaagatgaaatccaatttctacgtacgaatgatgaggtg gtgctgcagtgcatcttcacatcccaacaggagcatctgaaactgtgcctggctgcagag ggctttggctgcagactctgctgtctggagtccacttccaactgcaagaatgttcctcca gacctgtcggtgtgttcctttgtgctggcccagtgtctgtctgtcagagctctgcaggag atgctggctaacagggaggaccaagcagcaggggctggtcagggaggtggtcatcgcacc ctcctctacggtcatgctgtactgctcatacactcctacagcaggatgtatctttgctgt ttgtccacatcccagtcttcgacagataagctagcatttgatgttggtctgcaggatgat aaaacaggtgaggcatgctggtggacaattcacccggcatccaagcagaggtcagagggg gagaaggtccgtgtcggggacgacctcatcctggtcagtgtgtcatctgagagatacctg catttgtcctatgggagtgtgatagacaatacgagtgaaagtggcagtcttattgtggac gcagccttccagcagaccctctggcgagtcgcccccatctgttctgggagtggagttgct caagggtatctgaagggcggggacacattgaggctgctgcatggacacacagacgaatgt ctgactgtcccgtctacagaccagggggaggagctacgcaaaatggtgcactacgagggt ggagcagtgtcgagtcatgcccgctctctctggaggctggagatcctgcgtgttgcctgg agtagtagccacacacgctggggtcagccattcaggctccgccatgtcaccacagggagg tacttgagtctgaccgaggagagaggccttcacctggtggacagggagagggccgacgtg aagtccacatccttctgcttccgaccctccaaggagaagctagaatgtggcccaaagaag gacactgatggtatgggtgcctcagagatcaagtatggagactccttgtgctacgtccag catgtggactctggtctgtggctcacctaccaagccattgatgccaagtgtgcccgcttg ggagcggtgcagcgcaaggccattatgcacaatgagggtcacatggatgatggtctgagc ctgtcccgttctcagtgggaggagtcccacacggccagactcatccgcagcaccgtcctc ctcttcacaggcttcatcaggagacttgatggtctcagtcagcaagcgaacatcccctcc ttcaacctgccactggagatagtggccctaagtttgcaggatctgattggctacttccag ccacctggggaggggctaggacatgaggctaggcagaacagtgtgcgagctctgaagaac agacagaatctatttcaagaggagggggtcatcgctttagttcttgactgcattgaccgt ttacacctatacagcagtgcctctcattttgctgcagctgctgggaaggaggcaggtgat gactgggagaacatcctcaactccttctatgaactactggctgttcttatcaggggaaat cgtaggaactgtgcccagttctcaggctccctggactggctggtgagcaggctggagaga ctggaggcctccactggtgtcctggaggttttacactgtgtccttgtggagagtcctgag actctcaactttataagggaaggacacattaaatccatcatctctctactcgataagcat gggcggaaccataaggtcctggatgtgctgtgttctctctgtgtgtgtcatggtatggca gtgcgttccaaccagcatctgatctgtgataacctgctaccagagcgagacctgcttctc cagactcgccttgtcaaccaggtcaccagcatgaggcccaacatcttcctggccctcggt gatgactcggcccagcacaggaggtggtactatgagatgactgtagaccaggtggagccc ttcctcacggctgagcccactcacctgcgtgtgggctgggccaacaaggagggttacaac ccctatctcacgggtggagaggcctgggggggcaacggggtaggagatgacctcagctcc tatggctttgacgggctgtacctctggtcaggctgtgttggccggagagtgagctctccc tatcaccaccttctgagggaggacgatgtggtcagctgctgcattgacctcgttgccacc tgtatctccttccgggtcaatgggcagccggtccagggcatgctggagaacttcaacact gacggactgctcttcccagtggtcagcttctcggctggtgtcaaggtgcgttttctgctg ggtgggagacatggagagttccatttcctgccccctccaggcttcgccccgtgttccgag gctctgctccccagggtgaagctgagggtggagccgtgtcaggacttcacccaggagcaa taccttctgggccccactgtacccctcaccccagcaacctttacccctagtccagtagac atcagccaggtggtgttgcccgttcaactggagcatatccgtgagagactagcagagaac acccatgagctgtgggtcatggacaagattgaccttggatggaccaatggagctgtgaga gatgacagtaagaagcaggacccctgtctggtggagttctcgaggctcccagaacaggag cgaaaccacagccttcagatgtcccaggacacactccggactctcattgcccttggtttg catattggactggcagatggccgtgctgatgagggagtgagatacctgaggctctccacc aaatatgagatgcctagtgggtacagaccagccccggtagacctgagccacatcatcctg agtcctgcccaggaggcggtggtggagctactggctgagaacgatcacaacgtgtgggcc agggaccggatcaggcagggctggacctacagctcacaccaggatgtgaaggccaagcgg agcccccacctggtgccctacagcctgctggatgagaggagcagacaatctggcagagac ggtgtgagggaggccgtgtgcaccctgctgtgctacggctacagtctggagcccctggac caggacagaggtgttatgccagacccatgtcacacagcggctgagaagttcagggtcttc agggcagacaagtcgtatgctgtgaccagggggaagtggtactttgagtttgaggcggtg acggcaggggacatgcgggtaggctgggctcgtccccactgcacaccgaatggggaacta ggatcagacatgcaggcttttgtgtttgacggctccaaggcccagtggtgtcaccaggga ggtgagcccctgggtcggccctggcagagtggtgatgtggtgggctgtatggttgacatg ggagaatgcaccatgatggtcactctcaatggagaggtgcttttgaacgaccgcggatca gagctggctgccaaggactttgacatcaaccagggcttcctccctgtgtgtagtctcggg gtgaaccagaaggccaggctgaatctgggtcgtgacgtggcctcgctgtgttacttcaca gtgtgtggcctactggaaggttataagccatttgctgtcaacatggccagagacccagcc ctgtggatgagctggagacaaccacagttcatccctgtacagacagaccatgatagcata caggtgacaagaatcactgggtccactgagagcccaccgtgcctaaaggtaacacagagg tcattggggccccagagttgtggcagtgacatggggttctacagactcagtatgcctata gagtgtgctgaggccttctccagaccagtaggtgctactctacctatcagcagcagtgtc tccacagccaggaaagacctgcaggagtttgaggtggactctgactttgagatgctgctg aaatcagctcatgtttacactggctccagggatgagcttaaccacaaggactacagccat gataaaacatccaaactcaaacaacggttcatgttgaagaaatccaaaccagagttgaac aaaagccactcatctgcccgtctactgcaggaggttcatgctgacaaagacgactatgac catctggcccagtccactacgtactattactcagtgagggtgttacctggtcaggacccc tccactgtctgggtgggctgggtcacctctgacttccaccagcaccagctgacctttgac ctggaaaagatccgcacagtgaccgtcaccctcggagatgacatgggcaaggtccatgag agtgtgaaacgtagtaactgctacatggtgtgcgccggagagagcacgggcctggggcag agcaggaggagtgcaggcctggccataggctgtctgatagacaccaccactggactgcta acattcagctccaacggcatggagctggggaccttctttcaggtggagcccagcactagg ctgtttcctgcagtctttgccaaggccaacagctccaatgtgttccagtttgagctaggg cgcgtaaagaacatgctgcccctgtcagcgggtctgttcaggagccagaggaggaatgct atgccccagtgtccccccaggctgcaggtgcaggtgctgtcgcccatcctttggacccgt gtaccagaccacaccctgagggtgcaggctgcccaccctgatgaccgtctcggctggagg gtccagtgcttagagcccctgcaggtcatgaccctgctcatcccagaggagaacaggtgt gtggacatcctggaactctctgagttaggtgaccttctgtctttccatcaccacaccctg ctcctctactctgccctctgtgctctgggcaatactcgtgtgggccacgccctctgcagc cacctggaccaatcacagctcctctatgccattcagagcccccgcctccccgggccgctc cgctctgccttctaccacctcctgggccaggtgcacctcagcacccacgccacggcccgc ctcgctatgaaccacgagtacatcgtccccatgacggagcagaccagggccatcaccctc taccccagccccaggactagtcgaagcccccagtgggttcccagaatgggcctcagcacc tccctcagaccccggatgcacttcacctccccctgcttcatcagaggagatggcatggga gtcaatggtgatacttgtggtgatggtgtggttgcaactggggaaggcattcatatagac agcccagagatcccactggaacttctgaaggacctgacagggaagatgctgactgaggct gtgtgggctgtggggcagggtgtgagggatcctgaagggggcagcattgagctgctgctg gtgcccctaattcggctgttccacaccctgctggtgatggggttgtttggggacgaggac ctagggaaggtgctgacactgatcgagcctggagtcttctcccgacctgcagaatgttcc ccagaagaagcggaggaggagcaggaagaggaagagcaggaggatgaaaatgtgccagat agtgatagagaaagtgtgatggagagggagggtgacaaaaggaggacaattccaaagctt ccaacaaaaggactgcttcagatgaagctaccagaagctgtcaaacttgagatctgccac ctgttccaatacctgtgtgactgtcaggtgcgtcacagggtggaggcggtggtggccttc tcagacactttcgtggggtacctgcaggagaaccagcacttccgctacaacgaggtgata caggctctccacatgtctgctgccctcaccgcccgcaagaccaaggagttccgttccccg ccacaagaacagatcaacatgttactgggcttcagagaggagcagggggactgtccatgt ccagaggacatcagagagcagctgctggacttccaccaggacctcatgactcactgtgga attgaagttgaccatgacacagaggttgtggaggattccaatcgctccatcaaagatcgt ctcttcagcctggttgggagagtaatcggcttgaagaggagatctgcagatcctgaagag gaagacagagcacagaataccatgactcttcagcagctcatctctgacacggtggtgcgc tgggcccaggagtgtgtgatagagaacccagctctggtcagggccatgttctctctgctg caccggcagtacgagggcttggggggccagatgggcactcccctccacaaggcctacacc atcagccaggtgtcagtggaggacaccatggccttgctggcctctctggtgcagattcgc tctctgctcagcgtccgcatgggcaaggaggaggagagactcatgatccggggactggga gacataatgaacaacaaggtgttctaccagcaccccaacctgatgagggttctggggatg cacgagacagtcatggaggtgatggtgaacgtcctgggggaaggggagaccaaggagatc acctttcctaagatggtggcccattgctgtcgcttcctttgttacttctgtcgcatcagt aggcacaatcaagggtccatgttcgagcacctcagctacctgttggataatagcagtgtt ggcctagcatctccgtcaatgcgtggagccacccctctggatgtggcagctgcctctgtc atggacaacaatgagctggccctggccctgagggaaccagacctggaaaaagtggtgcag tacttggcaggctgtggtctacagagttgtcgcatgctggtgtctaaaggctaccctgac attggttggaaccctgtggagggggaacgctacctggacttcctacgctttgctgtcttc tgcaacggggagagtgtggaggagaatgcctacttggtggtgaggctgctgattcgccgt ccggagtgttttggccccgccctgcgaggtgagggtggcgatggtctcctggcagccatg gaggaagccatcaggatctcagaggacctgtctatggacggaccctccacgacctatgag tccaatagaacactgaacgtgctgcaggatgaggaggatgacataatccacatgggccac tccatcatgaccttctactccgccctcatcgacctgctgggccgctgtgccccggagatg cacctgatccatgctgggaagggcgaggccatccgtatccgggccatcctgaggtccctc atccccatccaggacctggagggagtcatcggcatccccttccaaatcccctctctagca aaagatggcaccgtagtcgaaccagacccatccactgtgttctgcccggaccacaaggca gccatggtgctgttcctggaccgtgtgtatggcatcgaggaccagaacttcctgctccac ctgctggaagtgggcttcctgccagacctgcaggctgcggcctctctggacacaactgat ctgagtgccacagacatggccctggctctgaacaggtacctatgtacggctgtgctgccc ctgctcactaagtgctccagcctgttctctgggacagagggccaggggccgctggtggat gctctcctccaggccgtctaccgcctgtccagggccctcagcctcaccaaggcccagaga gacgccatcgaggactgcatgctggctatatgcagtaagctcaggccgtccatgatgcaa cctctactccgacggcttgtttttgatgtgccccttctgacaaaccacactaaaatacca ctcaagctgttgaccaatcactatgagcagagctggaagtactactgtctgattggaggt ttggggcacctgggctccgcctcagaggaggagcttcacctctccaggaagttgttctgg ggagtgttcaatgctctgtccaggaagcactatgacgctgagctctccaggctggctctg cagtgtctggcagctgcagctggagccctccctcctgaccacatggaccctggctgtgta gcctggatggagagacacccctccatggatgcacagggacactttgacccccagcctgta gacacctccaatgtgtcagtaccagagaaactggaatttctggtgaataaatatgcagaa cacacccatgagaagtggtcaatggacaagtttgccaatggctgggtccatggggagctc tgtgaaaagaccaaagtacaccctctcttgaagccttacagagctctggctgagagggac aaagaggcgtatcgctggtctgtaaaggagacagtgcgaagtatgttggcctttggctgg accatagagagaactaaagagggcgatggccttggcctactcacctgctcacgccgcatc tcccaggctggacagctgtcgtttgaaggagcatcaaccttcacccccaagccaatggac atgagcagtgtgacactctcatgggaccagtgttctgtgactgaattgctggctgagaac taccataacacctggtccaggaagaagaagcaggaagtggatgctaaagggggagggggt cattctacgctggtgccctatgataccctccctaccaaggagaaagccaaactgagagag aaagcccaggaagtcctgaagttcttccagctgaacggctacacagtgtggagggacaga aaggcagcagagatggactcaccagccatagcaaaccgttttgcctacactttcctacag cagctcctctcgtacacagaggaggcccaagaatacatgcaggagctggagcttatgcag gcaagaggtccgataccaatagtagaggctccccaccaacagcagattgactttttcagc aaggtggcgttaccccttctggagcagtacctgaagaaccatcgcctctacttcctttcc accgcagccagatcacgaggcaacggaggtcaggcctccaataaggagaaggagatggtc accagcctgttctgcaaattgggagctcttgtcagacaaaggatctctctgtttgggagc gatgcaccttccattgtcagctgtcttctcatactggcccagtctctggatgtcaggact ttgatgaagactgctccagaatcagccagggtctcactacggtccttcttcgaggctgca gcggtggacctggagatgaccgtggagaacctctctatgacccagagctggacccagtcc agagaggtggcccagatcctggactacaccaataccgccctgctgccgactctcacctcc atttttgaacacctcagccacaatcagtatggagaggacctcttggtggacagtgtccag gtgtcctgttataagatcctcaacagcctccactcacttggcatcagcaaaagtttctac gtggaggggcagagaccgtcagcaggagcatgtctggcagcgctgtcaggggctttccct gtgtgtttcctggagccagctctgaatgaggacaacccgtactccatctacaacaccatg agccccagagagcgagaggatgtgggagttccagacgaggtggaggaggtgtgtcctctc ttgccatctctgcagcagcttctgggggaggtggaggagctggcaggggcaggctcaggg gcacgccaggcccagtacagccatgtcaccgagatcaccctacccttgctctgcagctac gtgtcccgttggtggcagcatggtcccgagggccagctggagagcccggtctgcacctca ctcacctcccagcatgcaagcacactgctgggcaacatcctccgcatcatccacaaccac ctgggaacaggccagggagactggatgaagcgcctagcagttttctctcagccaatcatc tgccaggcccacccccagttgctgaggagccacttcctgcctctgatggagaaactgaag aagagggcagaatcagtgcttcaggaggaggagcagataaaggctgaggggagggccgat gcgtctgaggcggagttacagattcaggagaaattcattgtgctggtgcgagacctctac gccttttaccctgtcctcatcccattcgtggactacaatagagcaagttggctacgggaa ccgagccatgaggctgagaagatgttcggcatggtggcagagatcttcatattctggacc aagtctcacaacttcaaatgggaggaacagaactatgtggtccagaatgagatcaacaac atggctttcttggtcaataataacaatcacaaaatgtccaaggtgtcagaccaggagagg aggaagatgaagcggaaaggggatcgctactccacacagacctctctcatcgtagcctcc ctgaagagattgcttcctgtgggactgagtgtgtgttccccagcagtccgcggccttatc acactggccaagagccgcttcactcagaaggacacagaggacgagattcgagagagcatt cataatggcctgctacgtcttcagagcaaacaggaggccccaggggctcggtggcaggat gtcctgttcagggacttcccaggctccacacgggacacctcggaccctctgaggacagta gaaagggtcctggacattgcttgcgtgctttaccacctggaccaggtagagcatccccag aggaagaagacagtgtggcacaaggtgttatccaaacagaggaagagagctgtggtggcc tgccttagaatggctcctctctacaacctacccaggcaccgggctgtcaacctctttcta cagggctatgacaagtcctggatatctgctgaggagcactcctttgaggaaaagttggtt gacgatttggctagagctggaaagcaggaacgttctgagagagaggaggaaggggcagga gaggacgatgacaaacagattgatccgctcctgcagctcatcacactgttcagtcggagt gctctgaccgagaggagtaagcttggcgatgacagtctttacatgtcctatgctgccata atggcaaagagttgctgtggtgaagaggatgaggaggtgaaaagctttgaagagaaggag atggagaaacagaagctgttgtatcagcaggccaggctgcatgaccgtggagctgctcag atggtcctccagactatcagtgctagtaaaggtgacatggggtccatggtggcctccact ctgaagcttggtatttctattctgaatggaggaaataccactgttcagcagaaaatgttg gattacctgaaagagaagagggatgtgggtttcttccagagtgtggcaggactcatgcag tcttgtagtgtgctggatttgaatgcgtttgagaggcagaacaaagccgaaggattaggg atggtcatcgaggagagctcaggggagaaggttatgcctgacgagaagttgacctgtgat ctttttcgcttcctacagctcctctgtgaaggacacaactcagattttcagaattatttg agaacacaaacaggaaacaacacgactgtgaacatcattatatccactgtggactacctt ctcagagtgcaggagtcgataagtgatttctactggtattactctggaaaggatgtgatt gacgaacatggccagcgtaacttctccaaggccatcagtgtggccaaacaggtcttcaac tctctcacagagtacatccaggggccgtgtactggtaaccagcagagtctggcccacagt cgcctatgggatgcggtggtgggctttctccatgtctttgctcacatgcagatgaagctg tctcaggattccagccaaattgaacttctgaaagaattgatggatttgcaaaaggacatg gttgttatgttgttgtccatgttagaaggtaacgtggtaaatggaacaattggcaagcag atggtggacatgttggtggaatcatctagcaatgttgagatgatcctaaagttcttcgac atgttcctcaaactcaaagacctgacctcatctgacgcattcaaagagtatgatcacgac ggcaaaggtcgcatctccaagaaggacttccagaaggccatggaggcctacaagcgctac tctcaatccgagacccagttcctcctctcctgcacggagacggatgaaagcgagctcctg gattatgaggccttcgtggatcgcttccacgagccagccaaagacattggcttcaacatt gctgttctcctaaccaacctgtctgagcacatgcctcacgattcacgtcttggtaccttt ctgcagcttgcagagtgtgttctgagctacttccagccctacctgggccgtattgagatc cttggcagtggcaagcgcatcgagagggtctactttgagatcagcgagtccagccgcacg cagtgggagaagcctcaggtcaaagagtccaagagacagttcatatttgacgtggtcaat gagggcgacgggaaagagaagatggagatgtttgtcaacttctgcgaagacaccattttt gagatgcagctggctgcccagatatcagggacagacactggggagaggaccgcaggcaaa gaggctgaagaagaggaagaaaaagacagggggaagaatgacgaggagttggaaagatcc aaaatgggatttttctccatgtccacaatatggctcatcgtcttcgctctaccctatggc ttgatgatgctgatgtctatgctctctgtgaaaaacctgaagaagcatattaagaagaca actctgagggatgtagtcatggtatttgcttcctttttccaggccatgatcatgggtctg gtccactttgtctgttctgtagttcgcttcttcttatatgtactgtacatagtttttgta agtggaggactcatagagggggccaagaagataagggtgttcgacctttttggaggcatc cttgacccaacacttgatgaggtcacaggggggtcagggggatacagggagaggagatac agcacaaggtcctcctcccgggacgagctgagggtgctgggccagtcaacagtttcctcc agtgacaccaatgtcctgtcagacattttcggtctgcgagtgaggagagaaggaggtcaa tacagactaatgactcatgacttaacagccagtctgactgacctgttcaacacagccact ggccaacaatcccctgctgagcccaatgggaaagaccaggttgaaggtgccagagaagga gatagtaaagaaggagaagagaaaaattcagagttggagaaagcagaaagggaagattct gagaaggaggcgaaggctaaacggagagttaggatatgctccagcaaacctgaggagcca gagcctcaggaatcagccttctgggaaatgataaccactcaccagaagagactgttgaat tactttgcgagaaatttctacaacatgcggatgctggctttgtttgttgctttctctatc aacttcattctccttttctacaaggtgtcatcatcctcttctgtaagtgaggaagaggag aaggtggcagtgctctacgacagctcaggcggcatggatgaagaagaccccttggtcaat gacaacacctcaggcagtatgcagtttgtcctggaggagagcactggttacatggagccc tctctccgcttcctgtccgtcgctcacaccctcatctctttctgctgtatcattggctac tactgcttgaaggtcccgctggttatttttaagcgggagaaagacgtggcgaggaagatg gagtttgacggtctctatgtcactgagcagccacctgatgaggacatcaaaggccaatgg gacaggcttgtcatcaccacacaatcatttcccagtaattactgggataaatttgtgaaa aggaaggtgatggacaagtatgggaagttttatggttgtgaccgcatcagtgagctgctg gggctggataaggctgctctcgacttcagctccgagggacaggagaggagaagacccagg agagagggagcctggactgctctattaaactcaattgatgtcaagtatcaggtgtggaaa ctaggagtagtgttcactgacaactccttcctgtacctggcatggtatatgaccatgtct gtcctgggccactataataacttcttcttcgctgctcacctgttggatattgccatgggc tttaagaccctaagaaccatcctgacctctgttacccacaatggcaaacagttggtcctg actttggggctgctggcagtggtggtgtatctctacaccgtggtggccttcaacttcttc cgcaagttctacaacaagagtgaagatggagtagctctggacatgaaatgtgacgacatg ctcacttgctatatgttccacatgtatgtgggcgtgcgagcggggggtggcatcggtgac gagattgaggacccggccggggacgagtttgaggtggtcaggatcatctttgacatcacc ttcttcttctttgtcatcgtcatcctcctggccatcattcagggtttgataattgatgcc tttggggagctccgtgaccagcaggagcaggtgaaagaggacatggagaccaagtgtttc atctgtggaatcgggaatgactacttggacaatgtgccccatggattcgaaacacacact cttcaggaacacaacttggccaactatctattctttgtgatgtacctcattaacaaagat gaaacagaacacacgggccaggaatcctacgtatggaaaatgtaccaggagcgatgctgg gaattctttcctgttggtgactgtttccgtaaacagtatgaagaccagctctgctga

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