KEGG   Staphylococcus aureus subsp. aureus N315 (MRSA/VSSA): SA0837
Entry
SA0837            CDS       T00051                                 
Name
(GenBank) ORFID:SA0837; hypothetical protein, similar to 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
sau  Staphylococcus aureus subsp. aureus N315 (MRSA/VSSA)
Pathway
sau00290  Valine, leucine and isoleucine biosynthesis
sau00620  Pyruvate metabolism
sau01100  Metabolic pathways
sau01110  Biosynthesis of secondary metabolites
sau01210  2-Oxocarboxylic acid metabolism
sau01230  Biosynthesis of amino acids
Module
sau_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:sau00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    SA0837
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    SA0837
Enzymes [BR:sau01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     SA0837
SSDB
Motif
Pfam: HMGL-like HCS_D2 IPMS_D2
Other DBs
NCBI-ProteinID: BAB42077
LinkDB
Position
950291..951436
AA seq 381 aa
MIRIQDNTIRDGMQQSNVRKSLIIKKEVLKQINKLNINSVEVGMCTTIEDEFNIHQFRDI
LSPEKELVVLTRLNEKEIKKIVKLKIHNLVVKILLPISDLHIKEKLNFSNKYYIQKIKDC
LDILKKDKKGVDICFEDATRTSREKLKEYMEIISKYQVRTVTFADTVGCSTPLEYGDIFN
YFVKKYSNIIFSAHCHNDLGLATANTLAAILNGAKQIETTFLGIGERAGNAPIEEIITIL
TKKQIESTEFTLPDVYKTSINISKILDFQISENKPIIGENIFKHESGIHQDGTKKNINMY
QYLVPSDLGLKNSQVVQFPISNISSKKILHNKFKSIVNTEEIDENISFYKLVNKFSPEVA
PEDTVDLLQIIKRRSKDGNFK
NT seq 1146 nt   +upstreamnt  +downstreamnt
atgattcgaattcaagataatacaataagggatggtatgcaacaaagtaatgttcgaaaa
agtctaattataaaaaaagaagtattgaaacaaattaacaagttaaatataaattctgtt
gaagtaggcatgtgtacaactatcgaggatgaatttaatattcatcaattcagagacatt
ttaagtcctgaaaaagaattagtagtattgactaggcttaatgaaaaagaaataaaaaaa
atagtcaaattgaaaattcataatttagtggtaaaaatactattgccaatatctgacttg
catataaaagaaaagcttaatttttcaaataaatattatattcagaaaatcaaagactgc
ttggatatattaaagaaagataaaaaaggagtagatatttgttttgaagatgcaacaagg
acttctagagaaaaattgaaagaatacatggaaattatttcaaaatatcaagttagaaca
gttacatttgcggacactgtaggatgttcgacaccattagaatacggagatatttttaat
tactttgtaaaaaaatattctaacataattttttctgctcattgtcataacgatctaggg
ttggctactgcaaatacattagctgcaattttaaatggtgcaaagcaaatagaaactaca
tttttgggaattggtgagagagcgggtaatgctcctattgaggaaataattactattttg
acaaaaaaacaaatagaaagtacggaattcactttacccgacgtatataaaactagtatt
aatatttctaaaattctcgattttcaaatatcagaaaacaaacctataattggtgaaaat
atatttaaacatgaatcaggaattcatcaagatggtactaaaaaaaatataaatatgtat
caatatttagttcctagtgatttaggattgaaaaattcacaagttgttcagtttccaata
agtaatatttctagtaagaaaatcttgcacaataaatttaaatcaatagttaacactgaa
gaaattgatgaaaatatttctttctataaacttgtgaacaagttttcacctgaagtagca
cctgaagatacagtggatttacttcagataataaaaaggaggagtaaagatggaaatttt
aaatga

KEGG   Staphylococcus aureus subsp. aureus N315 (MRSA/VSSA): SA1862
Entry
SA1862            CDS       T00051                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
sau  Staphylococcus aureus subsp. aureus N315 (MRSA/VSSA)
Pathway
sau00290  Valine, leucine and isoleucine biosynthesis
sau00620  Pyruvate metabolism
sau01100  Metabolic pathways
sau01110  Biosynthesis of secondary metabolites
sau01210  2-Oxocarboxylic acid metabolism
sau01230  Biosynthesis of amino acids
Module
sau_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:sau00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    SA1862 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    SA1862 (leuA)
Enzymes [BR:sau01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     SA1862 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer HCS_D2 ABC2_membrane_3
Other DBs
NCBI-ProteinID: BAB43144
UniProt: P63477
LinkDB
Position
2102502..2104031
AA seq 509 aa
MSSHIQIFDTTLRDGEQTPGVNFTFDERLRIALQLEKWGVDVIEAGFPASSTGSFKSVQA
IAQTLTTTAVCGLARCKKSDIDAVYEATKDAAKPVVHVFIATSPIHLEHKLKMSQEDVLA
SIKEHVTYAKQLFDVVQFSPEDATRTELPFLVKCVQTAVDAGATVINIPDTVGYSYHDEY
AHIFKTLTESVTSSNEIIYSAHCHDDLGMAVSNSLAAIEGGARRIEGTVNGIGERAGNAA
LEEVALALYVRNDHYGAQTALNLEETKKTSDLISRYAGIRVPRNKAIVGQNAFSHESGIH
QDGVLKHRETYEIMTPQLVGVSTTELPLGKLSGKHAFSEKLKALGYNIDKEAQIDLFKQF
KTIADKKKSVSDRDIHAIIQGSEHEHQALYKLETLQLQYVSSGLQSAVVVVKDKEGHIYQ
DSSIGTGSIVAIYNAVDRIFQKETELIDYRINSVTEGTDAQAEVHVNLLIEGKTVNGFGI
DHDILQASCKAYVEAHAKFAAENVEKVGN
NT seq 1530 nt   +upstreamnt  +downstreamnt
atgagtagtcatattcaaatttttgatacgacactaagagacggtgaacaaacaccagga
gtgaattttacttttgatgaacgcttgcgtattgcattgcaattagaaaaatggggtgta
gatgttattgaagctggatttcctgcttcaagtacaggtagctttaaatctgttcaagca
attgcacaaacattaacaacaacggctgtatgtggtttagctagatgtaaaaaatctgac
atcgatgctgtatatgaagcaacaaaagatgcagcgaagccggtcgtgcatgtttttata
gcaacatcacctattcatcttgaacataaacttaaaatgtctcaagaagacgttttagca
tctattaaagaacatgtcacatacgcgaaacaattatttgacgttgttcaattttcacct
gaagatgcaacgcgtactgaattaccattcttagtgaaatgtgtacaaactgccgttgac
gctggagctacagttattaatattcctgatacagtcggctacagttaccatgatgaatat
gcacatattttcaaaaccttaacagaatctgtaacatcttcaaatgaaattatttatagt
gctcattgccatgacgatttaggaatggctgtttcaaatagtttagctgcaattgaaggc
ggtgcgagacgaattgaaggcactgtaaatggtattggtgaacgagcaggtaatgcagca
cttgaagaagtcgcgcttgcactatacgttcgaaatgatcattatggtgctcaaactgcc
cttaatctcgaagaaactaaaaaaacatcggatttaatttcaagatatgcaggtattcga
gtgcctagaaataaagcaattgttggccaaaatgcatttagtcatgaatcaggtattcac
caagatggcgtattaaaacatcgtgaaacatatgaaattatgacacctcaacttgttggt
gtaagcacgactgaacttccattaggaaaattatctggtaaacacgccttctcagagaag
ttaaaagcattaggttataacattgataaagaagcgcaaatagatttatttaaacaattc
aagaccattgcggacaaaaagaaatctgtttcagatagagatattcatgcgattattcaa
ggttctgagcatgagcatcaagcactttataaattggaaacactacaactacaatatgtc
tctagcggccttcaaagtgctgttgttgttgttaaagataaagagggtcatatttaccag
gattcaagtattggtactggttcaatcgtagcaatttacaatgcagttgatcgtattttc
cagaaagaaacagaattaattgattatcgtattaattctgtcactgaaggtactgatgcc
caagcagaagtacatgtaaatttattgattgaaggtaagactgtcaatggctttggtatt
gatcatgatattttacaagcctcttgtaaagcatacgtagaagcacatgctaaatttgca
gctgaaaatgttgagaaggtaggtaattaa

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