Staphylococcus aureus subsp. aureus SA268 (CA-MRSA): SA268_0042
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Entry
SA268_0042 CDS
T03790
Symbol
mecA
Name
(GenBank) Penicillin-binding protein PBP2a, methicillin resistance determinant MecA, transpeptidase
KO
K02545
penicillin-binding protein 2 prime [EC:
3.4.16.4
]
Organism
saug
Staphylococcus aureus subsp. aureus SA268 (CA-MRSA)
Pathway
saug00550
Peptidoglycan biosynthesis
saug01100
Metabolic pathways
saug01501
beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:
saug00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SA268_0042 (mecA)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01501 beta-Lactam resistance
SA268_0042 (mecA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
saug01011
]
SA268_0042 (mecA)
09183 Protein families: signaling and cellular processes
01504 Antimicrobial resistance genes [BR:
saug01504
]
SA268_0042 (mecA)
Enzymes [BR:
saug01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.16 Serine-type carboxypeptidases
3.4.16.4 serine-type D-Ala-D-Ala carboxypeptidase
SA268_0042 (mecA)
Peptidoglycan biosynthesis and degradation proteins [BR:
saug01011
]
Peptidoglycan biosynthesis and degradation
DD-Transpeptidase (Class B PBP)
SA268_0042 (mecA)
Antimicrobial resistance genes [BR:
saug01504
]
Gene sets
beta-Lactam resistance modules
Methicillin resistance [MD:
M00625
]
SA268_0042 (mecA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Transpeptidase
PBP_dimer
MecA_N
DUF1310
HK_sensor
Motif
Other DBs
NCBI-ProteinID:
AII54609
LinkDB
All DBs
Position
complement(48188..50194)
Genome browser
AA seq
668 aa
AA seq
DB search
MKKIKIVPLILIVVVVGFGIYFYASKDKEINNTIDAIEDKNFKQVYKDSSYISKSDNGEV
EMTERPIKIYNSLGVKDINIQDRKIKKVSKNKKRVDAQYKIKTNYGNIDRNVQFNFVKED
GMWKLDWDHSVIIPGMQKDQSIHIENLKSERGKILDRNNVELANTGTAYEIGIVPKNVSK
KDYKAIAKELSISEDYIKQQMDQNWVQDDTFVPLKTVKKMDEYLSDFAKKFHLTTNETES
RNYPLGKATSHLLGYVGPINSEELKQKEYKGYKDDAVIGKKGLEKLYDKKLQHEDGYRVT
IVDDNSNTIAHTLIEKKKKDGKDIQLTIDAKVQKSIYNNMKNDYGSGTAIHPQTGELLAL
VSTPSYDVYPFMYGMSNEEYNKLTEDKKEPLLNKFQITTSPGSTQKILTAMIGLNNKTLD
DKTSYKIDGKGWQKDKSWGGYNVTRYEVVNGNIDLKQAIESSDNIFFARVALELGSKKFE
KGMKKLGVGEDIPSDYPFYNAQISNKNLDNEILLADSGYGQGEILINPVQILSIYSALEN
NGNINAPHLLKDTKNKVWKKNIISKENINLLTDGMQQVVNKTHKEDIYRSYANLIGKSGT
AELKMKQGETGRQIGWFISYDKDNPNMMMAINVKDVQDKGMASYNAKISGKVYDELYENG
NKKYDIDE
NT seq
2007 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaagataaaaattgttccacttattttaatagttgtagttgtcgggtttggtata
tatttttatgcttcaaaagataaagaaattaataatactattgatgcaattgaagataaa
aatttcaaacaagtttataaagatagcagttatatttctaaaagcgataatggtgaagta
gaaatgactgaacgtccgataaaaatatataatagtttaggcgttaaagatataaacatt
caggatcgtaaaataaaaaaagtatctaaaaataaaaaacgagtagatgctcaatataaa
attaaaacaaactacggtaacattgatcgcaacgttcaatttaattttgttaaagaagat
ggtatgtggaagttagattgggatcatagcgtcattattccaggaatgcagaaagaccaa
agcatacatattgaaaatttaaaatcagaacgtggtaaaattttagaccgaaacaatgtg
gaattggccaatacaggaacagcatatgagataggcatcgttccaaagaatgtatctaaa
aaagattataaagcaatcgctaaagaactaagtatttctgaagactatatcaaacaacaa
atggatcaaaattgggtacaagatgataccttcgttccacttaaaaccgttaaaaaaatg
gatgaatatttaagtgatttcgcaaaaaaatttcatcttacaactaatgaaacagaaagt
cgtaactatcctctaggaaaagcgacttcacatctattaggttatgttggtcccattaac
tctgaagaattaaaacaaaaagaatataaaggctataaagatgatgcagttattggtaaa
aagggactcgaaaaactttacgataaaaagctccaacatgaagatggctatcgtgtcaca
atcgttgacgataatagcaatacaatcgcacatacattaatagagaaaaagaaaaaagat
ggcaaagatattcaactaactattgatgctaaagttcaaaagagtatttataacaacatg
aaaaatgattatggctcaggtactgctatccaccctcaaacaggtgaattattagcactt
gtaagcacaccttcatatgacgtctatccatttatgtatggcatgagtaacgaagaatat
aataaattaaccgaagataaaaaagaacctctgctcaacaagttccagattacaacttca
ccaggttcaactcaaaaaatattaacagcaatgattgggttaaataacaaaacattagac
gataaaacaagttataaaatcgatggtaaaggttggcaaaaagataaatcttggggtggt
tacaacgttacaagatatgaagtggtaaatggtaatatcgacttaaaacaagcaatagaa
tcatcagataacattttctttgctagagtagcactcgaattaggcagtaagaaatttgaa
aaaggcatgaaaaaactaggtgttggtgaagatataccaagtgattatccattttataat
gctcaaatttcaaacaaaaatttagataatgaaatattattagctgattcaggttacgga
caaggtgaaatactgattaacccagtacagatcctttcaatctatagcgcattagaaaat
aatggcaatattaacgcacctcacttattaaaagacacgaaaaacaaagtttggaagaaa
aatattatttccaaagaaaatatcaatctattaactgatggtatgcaacaagtcgtaaat
aaaacacataaagaagatatttatagatcttatgcaaacttaattggcaaatccggtact
gcagaactcaaaatgaaacaaggagaaactggcagacaaattgggtggtttatatcatat
gataaagataatccaaacatgatgatggctattaatgttaaagatgtacaagataaagga
atggctagctacaatgccaaaatctcaggtaaagtgtatgatgagctatatgagaacggt
aataaaaaatacgatatagatgaataa
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