Streptomyces auratus: SU9_025045
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Entry
SU9_025045 CDS
T07630
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sauh
Streptomyces auratus
Pathway
sauh00290
Valine, leucine and isoleucine biosynthesis
sauh00660
C5-Branched dibasic acid metabolism
sauh01100
Metabolic pathways
sauh01110
Biosynthesis of secondary metabolites
sauh01210
2-Oxocarboxylic acid metabolism
sauh01230
Biosynthesis of amino acids
Module
sauh_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sauh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
SU9_025045 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SU9_025045 (leuC)
Enzymes [BR:
sauh01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
SU9_025045 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
SU9_025045 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
QTZ94307
UniProt:
J2K631
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Position
5725978..5727408
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AA seq
476 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKAGRRVRRTDLTIAT
EDHNTPTLDIDKPIADPVSRTQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLAPFKTMAITVDGELPEGVTA
KDLILAIIARIGTGGGQGYVLEYRGPAIEKLSMEARMTICNMSIEAGARAGMIAPDKTTF
DYLQGRDHAPQGEEWDAAVAYWKTLRTDEDAVFDAEVHIDASALAPFVTWGTNPGQGAPL
SSSVPDPASYEDASERYAAEKALEYMGLTAGQPLRDITVDTVFVGSCTNGRIEDLRSAAA
ILEGRQVADGVRMLVVPGSVRVSLEAVAEGLDKVFTAAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDVAVATPAGV
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgggacggacactcgcggagaaggtctgggacgatcatgtcgtccggcgcgcggaaggc
gagcccgaccttctcttcatcgatctgcacctgctgcacgaggtcaccagcccgcaggcc
ttcgacggcctgcgcaaggccggtcgccgggtgcgccggacggatctgaccatcgccacc
gaggatcacaacaccccgaccctcgacatcgacaagccgatcgccgacccggtctcgcgc
acgcagctggagacgctgcgcaagaactgtgcggagttcggggtgcggctgcacccgctg
ggcgatgtcgagcagggcgttgtccacgtcgtgggaccgcagttgggactgacccagccc
ggcaccaccgtggtctgcggtgacagccacacctccacccacggcgccttcggcgcgctg
gcgttcggcatcggcaccagccaggtcgagcacgtcctggccacgcagacgctgccgctg
gccccgttcaagaccatggcgatcaccgtggacggtgagctgcccgagggcgtcaccgcc
aaggacctgatcctggcgatcatcgcgcggatcggcaccggtggcggccagggctacgtc
ctggaataccgcggcccggccatcgagaaactgtcgatggaagcccggatgaccatctgc
aacatgtccatcgaggcgggcgcgcgggccggcatgatcgcccccgacaagaccaccttc
gactacctgcagggccgcgaccacgccccccagggcgaggagtgggacgccgcggtcgcc
tactggaagaccctgcgcaccgacgaggacgcggtcttcgacgccgaggtgcacatcgac
gcttccgcgctggcgccgttcgtcacctggggcaccaaccccggccagggcgcgccgctt
tcgtccagcgtccccgacccggcttcgtacgaggacgcctcggagcgctacgccgccgaa
aaggccctggaatacatggggttgacggcgggccagccgctgcgcgacatcacggtggac
accgtcttcgtaggttcgtgcaccaacggccgcatcgaggacctgcgctccgcggccgcg
atcctggagggccgccaggtcgccgacggcgtacggatgctggtcgtgcccggctcggtg
cgcgtctccctggaggccgtcgccgagggcctggacaaggtcttcaccgcggccggcgcc
gaatggcggcacgcgggttgctcgatgtgtctgggtatgaaccccgaccagctggcgccc
ggcgagcgctccgcctccacctccaaccgcaacttcgagggccgccagggcaagggtggc
cgcacccacctggtctcgccgcaggtcgccgccgcaacagcggttctcggccatctggcc
tcaccggccgatctctctgacgtcgccgtcgccacgcccgcgggagtctga
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