Staphylococcus aureus subsp. aureus ST228/10497 (MRSA): SAI2T2_1015140
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Entry
SAI2T2_1015140 CDS
T03144
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sauj
Staphylococcus aureus subsp. aureus ST228/10497 (MRSA)
Pathway
sauj00290
Valine, leucine and isoleucine biosynthesis
sauj00660
C5-Branched dibasic acid metabolism
sauj01100
Metabolic pathways
sauj01110
Biosynthesis of secondary metabolites
sauj01210
2-Oxocarboxylic acid metabolism
sauj01230
Biosynthesis of amino acids
Module
sauj_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sauj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
SAI2T2_1015140 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SAI2T2_1015140 (leuC)
Enzymes [BR:
sauj01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
SAI2T2_1015140 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
SAI2T2_1015140 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
CCJ13400
UniProt:
A0A7U7IG70
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Position
2055175..2056542
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AA seq
455 aa
AA seq
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MGQTLFDKVWNRHVLYGKLGEPQLLYIDLHLIHEVTSPQAFEGLRLQNRKLRRPDLTFAT
LDHNVPTIDIFNIKDEIANKQITTLQKNAIDFGVHIFDMGSDEQGIVHMVGPETGLTQPG
KTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTLWQTKPKNLKIDINGTLPTGVYAK
DIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRMTICNMAIEGGAKYGIIQPDDITFE
YVKGRPFADNFAKSVDKWRELYSDDDAIFDRVIELDVSTLEPQVTWGTNPEMGVNFSEPF
PEINDINDQRAYDYMGLEPGQKAEDIDLGYVFLGSCTNARLSDLIEASHIVKGNKVHPNI
TAIVVPGSRTVKKEAEKLGLDTIFKNAGFEWREPGCSMCLGMNPDQVPEGVHCASTSNRN
FEGRQGKGARTHLVSPAMAAAAIHGKFVDVRKVVV
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgggtcaaacattatttgacaaggtgtggaacagacatgtgttatacgggaaattgggc
gaaccgcaactattatacattgatttacaccttatacatgaagttacttctcctcaagca
tttgaaggacttaggcttcaaaacagaaaattaagacgcccagatttaacatttgcaaca
ctcgatcacaatgttcctactattgatattttcaatattaaagatgaaattgcaaacaaa
caaatcacaacattacaaaaaaacgccatagattttggggtgcatatttttgatatgggc
tctgatgaacaaggtattgttcacatggtaggacctgagacaggacttacacagcccggc
aaaacaatcgtttgtggtgactctcacacagcaacacatggagcatttggtgctattgca
tttggaattggaacaagtgaagttgaacatgttttcgcaactcaaacgctatggcaaaca
aaacccaaaaacttaaaaatcgatattaatggtaccttaccaacaggcgtctatgctaag
gacattattctgcatttaattaaaacgtatggtgttgattttggtacaggctatgctttg
gaatttactggcgaaacaattaaaaacctttcaatggacggtcgaatgactatttgtaac
atggctatcgaaggtggtgccaaatacggcataatccaacctgatgatataacatttgaa
tatgttaaagggagaccatttgccgataacttcgctaaatcagttgataagtggcgtgag
ctatattctgatgacgacgcgatatttgatcgtgtaattgaacttgatgtttcaacatta
gaaccacaagtgacatggggaactaatcctgaaatgggtgttaatttcagtgaaccattc
cctgaaatcaatgatatcaacgatcaacgtgcgtatgattatatggggttagaaccaggt
caaaaagctgaagacatcgacttagggtatgtttttctcggttcatgtacaaatgctaga
ctatcagatttgattgaagctagtcatattgttaaaggaaataaagttcatccaaatatt
acagctattgtcgtaccaggttctcgtacagtaaaaaaagaagcagaaaaattaggtcta
gatactatctttaaaaatgcaggatttgaatggcgtgaaccaggatgttcaatgtgttta
ggcatgaatcctgaccaagtacctgagggcgtacattgtgcatctacaagtaatcgaaac
tttgaaggacgacaaggcaaaggtgcaagaacacatttagtatcccctgctatggcagca
gcagctattcatggtaaatttgtggacgtaagaaaggtggttgtttaa
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