Streptomyces malaysiensis subsp. malaysiensis CGMCC0516: BV401_28700
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Entry
BV401_28700 CDS
T04980
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sauo
Streptomyces malaysiensis subsp. malaysiensis CGMCC0516
Pathway
sauo00290
Valine, leucine and isoleucine biosynthesis
sauo00620
Pyruvate metabolism
sauo01100
Metabolic pathways
sauo01110
Biosynthesis of secondary metabolites
sauo01210
2-Oxocarboxylic acid metabolism
sauo01230
Biosynthesis of amino acids
Module
sauo_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sauo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
BV401_28700
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BV401_28700
Enzymes [BR:
sauo01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
BV401_28700
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Motif
Pfam:
HMGL-like
IPMS_D2
Motif
Other DBs
NCBI-ProteinID:
AQA13803
UniProt:
A0ABN4W980
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Position
complement(6976296..6977987)
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AA seq
563 aa
AA seq
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MTNEFATRPVWNEQRPSPMPVHRYRSYAEEVEPVLLPDRTWPDRTITRAPLWCSVDLRDG
NQALAVPMSPARKHQFFQLLVGMGYKEIEVGFPAASATDLAFVREIIESDTVPDDVRLQV
LSPCRPELIDRTVEAVAGARKVTLHIYNPTSELQRRVVFRQERTQIRELAVASARRLAEA
AESLTGADVRLQYSPESFTGTELGFAAEVCNAVLDVWQPTPQRPAAICLPATVEMTTPNT
YADSIEWMSRNLERRDSVLLSLHPHNDRGTAVAAAELGLAAGADRIEGCLFGNGERTGNV
CLVTLGMNMFSRGVDPEIDFSDLGEVRRVVEECTELPVHERHPWGGELVFTAFSGGHQDA
ISKGISALADESHSSGSDLRDEHWQVPYLPIDPSDVGREYEPVVRVNSQSGKGGVAFVLN
DSYGLRLPQQLRADFAVLVQQVTDREGGELSPKRLRELFHTAYTSPPGVLRLLDRTPSSV
TVCLDGIDKEIPLNGPASLPAFADALTQLGLDLTLTSATAHELPEGGAIAYLSSGASWAV
GTGEDTVSAELDAAVGIINRTHH
NT seq
1692 nt
NT seq
+upstream
nt +downstream
nt
atgacgaacgaattcgcgacccgcccggtctggaacgagcagcgcccgagccccatgccg
gtccaccgctaccgctcgtacgccgaggaggtcgaaccagttctgctgccggaccggacc
tggccggaccggacgatcacccgtgccccgctgtggtgctcggtcgatctgcgcgacgga
aaccaggccctcgccgtgccgatgtccccggcccgcaagcaccagttcttccagcttctc
gtgggcatgggctacaaggagatcgaggtcgggttccccgcggccagcgcgacggacctc
gccttcgtccgggagatcatcgagagtgacaccgtcccggacgacgtccgcctccaggtc
ctctccccgtgccgtccggaactcatcgaccgcacggtcgaggccgtcgccggggcccgc
aaggtgaccctgcacatctacaacccgacctccgagctgcagcgccgcgtggtcttccgc
caggagcggacgcagatccgcgagctggccgtcgcgtcggcccgccggctcgcggaggcg
gccgagtcgctcaccggcgccgacgtacggctgcagtactcgccggagtcgttcaccggt
accgagctgggcttcgccgccgaggtctgcaacgcggtcctcgacgtctggcagcccacc
ccgcagcgcccggcggcgatatgcctgccggccaccgtggagatgaccaccccgaacacc
tacgcagactcgatcgagtggatgagccgcaacctggagcggcgtgactcggtcctcctc
tcgctgcacccgcacaacgaccgcggcaccgccgtcgccgccgccgaactcggtttggcc
gccggcgcggaccgcatcgagggctgcctgttcggcaacggcgaacggaccgggaacgtc
tgcctggtcacgctcggcatgaacatgttcagccgcggcgtcgaccccgagatcgacttc
tccgacctgggcgaggtccgccgggtggtggaggagtgcaccgaactgcccgtgcacgaa
cgccacccgtggggcggcgaactcgtcttcaccgccttctccggcggccaccaggacgcc
atcagcaaggggatctcggcactcgccgacgagtcccactccagcggctccgacctgcgc
gacgaacactggcaggtgccctacctgccgatcgacccaagcgacgtcggccgcgagtac
gaaccggtcgtccgggtgaactcccagtccggcaagggcggagtggcgttcgtgctcaac
gactcctacggactgcgcctgccccagcagctccgcgcggacttcgccgtactggtccag
caggtgacggaccgcgaaggcggcgaactcagccccaagcggctgcgcgagctcttccac
accgcgtacacctccccgcccggcgtgctgcggctgctggaccgtacgccgtcctcggtg
acggtctgcctggacggcatcgacaaggagataccgctgaacggacccgcttcgctgccc
gcgttcgccgacgcgctcacccagctcgggctggacctgaccctcacctcggccacggcg
cacgaactgccggagggcggcgcgatcgcctacttgagtagcggcgcgagctgggccgtc
ggcacgggtgaggacaccgtgtccgcggaactcgacgcggccgtcggcatcatcaaccgg
acgcatcactga
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