Streptomyces malaysiensis subsp. malaysiensis CGMCC0516: BV401_31355
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Entry
BV401_31355 CDS
T04980
Name
(GenBank) citramalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sauo
Streptomyces malaysiensis subsp. malaysiensis CGMCC0516
Pathway
sauo00290
Valine, leucine and isoleucine biosynthesis
sauo00620
Pyruvate metabolism
sauo01100
Metabolic pathways
sauo01110
Biosynthesis of secondary metabolites
sauo01210
2-Oxocarboxylic acid metabolism
sauo01230
Biosynthesis of amino acids
Module
sauo_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sauo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
BV401_31355
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BV401_31355
Enzymes [BR:
sauo01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
BV401_31355
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
HNHc_6
Motif
Other DBs
NCBI-ProteinID:
AQA14239
UniProt:
A0ABN4WBI7
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All DBs
Position
7580201..7581799
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AA seq
532 aa
AA seq
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MKDLPDDGFHVFDTTLRDGAQREGINLTVADKLTIARHLDDFGVGFIEGGWPGANPRDTE
FFARARAEIDFRHAQLVAFGATRKAGVLAEDDPQVKALLDSGAPVITLVAKSHDRHVELA
LRTTLEENLAMVRETVAHLRSQGRRVFLDCEHFFDGYRANPAYAKQVVATAHEAGAEVVI
LCDTNGGMLPGQIDAVVRTVLADTGARLGIHAQDDTGCAVANTLAAVDAGATHVQCTANG
YGERVGNANLFPVVAALELKYGRRVLPEGALEEMTRISHAIAEVVNLTPSTHQPYVGVSA
FAHKAGLHASAIKVDPDLYQHIDPERVGNTMRMLVSDMAGRASIELKGKELGFDLGGDRA
LVGRIVERVKERELAGYTYEAADASFELLLRQEVDGRPRRYFRVESWRAIVEDRPDGTHA
NEATVKLWAKGERIVATAEGNGPVNALDRALRVGLERIYPQLATMELVDYKVRILEGKHG
TESTTRVLVSTADGQGEWSTVGVGGNVIAASWQALDDAYAYGLLRAGVDPQE
NT seq
1599 nt
NT seq
+upstream
nt +downstream
nt
atgaaggatctgcccgacgacggtttccatgtcttcgacaccacgctccgcgacggagcg
cagcgcgagggcatcaacctgacggtcgcggacaagctgaccatcgcccgtcacctggac
gacttcggcgtgggcttcatcgagggcggctggcccggcgccaacccgcgcgacacggag
ttcttcgcccgggcccgcgccgagatcgacttccggcacgcccagctggtggcgttcggc
gcgacccgtaaggcgggggtgctcgccgaggacgacccccaggtcaaggcgttgctggac
tccggggcgccggtgatcaccctggtggcgaagtcccacgaccgccatgtggagctggcc
ctgcgcaccacgctcgaggagaacctcgcgatggtccgcgagaccgtcgcccatctgcgg
tcccagggccgccgggtcttcctcgactgcgagcacttcttcgacggctaccgggccaac
cccgcctacgccaagcaggtcgtcgccaccgcccatgaggcgggcgccgaggtggtgatc
ctctgcgacaccaacggcggcatgctccccggccagatcgacgcggtggtccgcaccgtg
ctggccgacaccggcgcccggctgggcatccacgcccaggacgacaccggctgcgcggtc
gccaacaccctcgccgccgtggacgcgggcgccacccacgtccagtgcacggcgaacggc
tacggcgagcgggtgggcaacgccaacctcttcccggtcgtcgcggccctggagctgaag
tacggccgccgggtgctgccggagggcgccctggaggagatgacccggatctcgcacgcg
atcgccgaggtcgtcaatctgacgccgtccactcaccagccctatgtgggtgtttccgcc
ttcgcccacaaggccgggctgcacgcctctgcgatcaaggtcgacccggatctgtaccag
cacatcgaccccgagcgggtcggcaacaccatgcggatgctcgtctccgacatggccggc
cgggcgtcgatcgagctcaagggcaaggagctgggcttcgacctcggcggcgaccgggcg
ctggtgggccggatcgtcgaacgggtcaaggagcgggagctcgcgggctacacctacgag
gccgcggacgcctccttcgagctgctgctgcgccaggaggtcgacggccgcccccgccgc
tacttccgggtcgagtcctggcgggcgatcgtcgaggaccgcccggacggcacccacgcc
aacgaggccaccgtgaagctgtgggccaagggcgagcggatcgtcgccacggccgagggc
aacggcccggtcaacgccctggaccgggcgctgcgggtggggctggaacggatctacccg
cagctggcgacgatggagctggtggactacaaggtccgcatcctggaaggcaaacacggc
accgagtccacgacccgggtgctggtctccaccgcggacggccagggggagtggtcgacg
gtcggcgtcggggggaacgtgatcgccgcgtcctggcaggccctggacgacgcctacgcc
tacgggctgctgcgggccggggtggatccccaggagtga
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