Staphylococcus aureus subsp. aureus SA40 (CA-MRSA): SA40_0944
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Entry
SA40_0944 CDS
T02849
Symbol
purH
Name
(GenBank) putative bifunctional purine biosynthesis protein [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclohydrolase]
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
saus
Staphylococcus aureus subsp. aureus SA40 (CA-MRSA)
Pathway
saus00230
Purine metabolism
saus00670
One carbon pool by folate
saus01100
Metabolic pathways
saus01110
Biosynthesis of secondary metabolites
Module
saus_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
saus00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
SA40_0944 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SA40_0944 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
saus04147
]
SA40_0944 (purH)
Enzymes [BR:
saus01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
SA40_0944 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
SA40_0944 (purH)
Exosome [BR:
saus04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
SA40_0944 (purH)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Phosphonate-bd
NSP2_assoc
Motif
Other DBs
NCBI-ProteinID:
AGW35989
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Position
1040539..1042017
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AA seq
492 aa
AA seq
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MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDG
RVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIE
NIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDSLDESYRQSLMIKVFEHTAEY
DEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATL
ALVKKFDTPAAVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAE
QLHSIFLEVIIAPKFTGEALDILKQKKNVRLLEIDMIIDSNEEEFVSVSGGYLVQDKDNY
VVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGAA
KIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPGGSIKDQDSIDMANKHGI
AMVVTGTRHFKH
NT seq
1479 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaagctattttgagcgtatcaaataaaacaggtattgtagagtttgctaaagcg
ttaacgcaattaaattatgaattatattcaacaggtggaactaaacgtatattagatgaa
gcaaatgtaccagttcgttctgtttcagacttaacacattttccagaaataatggatggc
cgtgttaaaacattacatccggctgttcatggtggcattttagctgatcgaaataaaccg
cagcatttaaatgaattatcagaacaacatatagatttaattgatatggtagtagttaat
ttatatccattccaacaaactgttgcaaaccctgatgtgacgatggacgaagcaattgaa
aatattgatattggtggtccaacaatgttacgtgctgcagctaaaaactataaacatgta
acaacaattgtacatcctgcagattatcaagaagtattgacgcgattaagaaacgattcg
ttagatgagtcatatagacaatcattaatgatcaaagtttttgagcatactgcagaatat
gatgaagcgattgtacgtttctttaaaggggataaagaaactttaagatatggagaaaat
ccacaacaatcagcgtattttgtgagaacttcgaatgctaagcacacgattgcaggcgct
aaacaattacatgggaaacaattaagctataacaatattaaagatgcagatgctacacta
gctttagttaaaaagtttgatacacctgctgcagttgcggttaaacacatgaatccatgt
ggtgttggtatcggtgacacgatagaacaagcatttcaacatgcgtatgaagcggatagt
caatcaatatttggtggaattgttgcattaaaccgagctgtaacacctgagttagcagag
caattgcatagtatctttttggaagttattattgcaccaaaatttacaggtgaagcatta
gatattttaaaacaaaagaagaatgtaagattattagaaattgatatgattatagacagt
aacgaagaagagtttgtttcagtatctggcggatatttagttcaagataaagacaattat
gtcgtgccaaaagaagaaatgaaagttgttacagaagttgcacctactgatgaacaatgg
gaagcaatgttattaggatggaaagttgtaccatcagtaaaaagtaatgcaattatttta
agtaataataaacaaactgtaggtataggtgctggacaaatgaatcgtgtcggtgctgct
aaaattgcgttagagagagctattgaaatcaatgatcatgtagcgttagtatctgatgga
tttttccctatgggagatacagttgaacttgcagcacaacatggtataaaggcaattatc
caaccgggtggttcgattaaagatcaagattcaattgatatggctaataaacatggtatt
gcaatggtagtcacaggcactcgacattttaaacactaa
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