Staphylococcus aureus subsp. aureus ST228/16125 (MRSA): SAI5S5_1015060
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Entry
SAI5S5_1015060 CDS
T03148
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sauw
Staphylococcus aureus subsp. aureus ST228/16125 (MRSA)
Pathway
sauw00290
Valine, leucine and isoleucine biosynthesis
sauw00620
Pyruvate metabolism
sauw01100
Metabolic pathways
sauw01110
Biosynthesis of secondary metabolites
sauw01210
2-Oxocarboxylic acid metabolism
sauw01230
Biosynthesis of amino acids
Module
sauw_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sauw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SAI5S5_1015060 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SAI5S5_1015060 (leuA)
Enzymes [BR:
sauw01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SAI5S5_1015060 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
ABC2_membrane_3
Motif
Other DBs
NCBI-ProteinID:
CCJ19289
UniProt:
A0A7U7IEW7
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Position
2052537..2054066
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AA seq
509 aa
AA seq
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MSSHIQIFDTTLRDGEQTPGVNFTFDERLRIALQLEKWGVDVIEAGFPASSTGSFKSVQA
IAQTLTTTAVCGLARCKKSDIDAVYEATKDAAKPVVHVFIATSPIHLEHKLKMSQEDVLA
SIKEHVTYAKQLFDVVQFSPEDATRTELPFLVKCVQTAVDAGATVINIPDTVGYSYHDEY
AHIFKTLTESVTSSNEIIYSAHCHDDLGMAVSNSLAAIEGGARRIEGTVNGIGERAGNAA
LEEVALALYVRNDHYGAQTALNLEETKKTSDLISRYAGIRVPRNKAIVGQNAFSHESGIH
QDGVLKHRETYEIMTPQLVGVSTTELPLGKLSGKHAFSEKLKALGYNIDKEAQIDLFKQF
KTIADKKKSVSDRDIHAIIQGSEHEHQALYKLETLQLQYVSSGLQSAVVVVKDKEGHIYQ
DSSIGTGSIVAIYNAVDRIFQKETELIDYRINSVTEGTDAQAEVHVNLLIEGKTVNGFGI
DHDILQASCKAYVEAHAKFAAENVEKVGN
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgagtagtcatattcaaatttttgatacgacactaagagacggtgaacaaacaccagga
gtgaattttacttttgatgaacgcttgcgtattgcattgcaattagaaaaatggggtgta
gatgttattgaagctggatttcctgcttcaagtacaggtagctttaaatctgttcaagca
attgcacaaacattaacaacaacggctgtatgtggtttagctagatgtaaaaaatctgac
atcgatgctgtatatgaagcaacaaaagatgcagcgaagccggtcgtgcatgtttttata
gcaacatcacctattcatcttgaacataaacttaaaatgtctcaagaagacgttttagca
tctattaaagaacatgtcacatacgcgaaacaattatttgacgttgttcaattttcacct
gaagatgcaacgcgtactgaattaccattcttagtgaaatgtgtacaaactgccgttgac
gctggagctacagttattaatattcctgatacagtcggctacagttaccatgatgaatat
gcacatattttcaaaaccttaacagaatctgtaacatcttcaaatgaaattatttatagt
gctcattgccatgacgatttaggaatggctgtttcaaatagtttagctgcaattgaaggc
ggtgcgagacgaattgaaggcactgtaaatggtattggtgaacgagcaggtaatgcagca
cttgaagaagtcgcgcttgcactatacgttcgaaatgatcattatggtgctcaaactgcc
cttaatctcgaagaaactaaaaaaacatcggatttaatttcaagatatgcaggtattcga
gtgcctagaaataaagcaattgttggccaaaatgcatttagtcatgaatcaggtattcac
caagatggcgtattaaaacatcgtgaaacatatgaaattatgacacctcaacttgttggt
gtaagcacgactgaacttccattaggaaaattatctggtaaacacgccttctcagagaag
ttaaaagcattaggttataacattgataaagaagcgcaaatagatttatttaaacaattc
aagaccattgcggacaaaaagaaatctgtttcagatagagatattcatgcgattattcaa
ggttctgagcatgagcatcaagcactttataaattggaaacactacaactacaatatgtc
tctagcggccttcaaagtgctgttgttgttgttaaagataaagagggtcatatttaccag
gattcaagtattggtactggttcaatcgtagcaatttacaatgcagttgatcgtattttc
cagaaagaaacagaattaattgattatcgtattaattctgtcactgaaggtactgatgcc
caagcagaagtacatgtaaatttattgattgaaggtaagactgtcaatggctttggtatt
gatcatgatattttacaagcctcttgtaaagcatacgtagaagcacatgctaaatttgca
gctgaaaatgttgagaaggtaggtaattaa
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