Staphylococcus aureus subsp. aureus Z172 (MRSA/VISA): SAZ172_1674
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Entry
SAZ172_1674 CDS
T02886
Symbol
folC
Name
(GenBank) Dihydrofolate synthase / Folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sauz
Staphylococcus aureus subsp. aureus Z172 (MRSA/VISA)
Pathway
sauz00790
Folate biosynthesis
sauz01100
Metabolic pathways
sauz01240
Biosynthesis of cofactors
Module
sauz_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
sauz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SAZ172_1674 (folC)
Enzymes [BR:
sauz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SAZ172_1674 (folC)
6.3.2.17 tetrahydrofolate synthase
SAZ172_1674 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AGY89774
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Position
complement(1784569..1785840)
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AA seq
423 aa
AA seq
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MNYLESLYWIHERTKFGIKPGVKRMEWMLAQFNNPQNNIKGIHVGGTNGKGSTVAYLRTA
LVENGYEVGTFTSPFIETFNERISLNGVPISNDAIVELVSRIKPVSEMMERETDLGVATE
FEIITAMMFLYFGEIHPVDFVIVEAGLGIKNDSTNVFTPVLSILTSIGLDHTDILGGTYL
DIARDKGAIIKPNVPVIYAVKNEDALKYVRERAIEQHAKPIELDREIVVVSQNDEFTYRY
KDYELETIILSMLGEHQKQNAALAITALIELNEQGLIELDFNKMIDGIESVRWTGRIEQV
HDKPLIILDGAHNSESIDALIDTIKQYHDKEKVDILFSAINGKPINEMVKHLSLIAHTFY
ATEFDFPKALRKEEIVGSIENDEIQLVDDYVEFIKNYQGDTLVITGSLYFISEVKSKLDF
EAL
NT seq
1272 nt
NT seq
+upstream
nt +downstream
nt
atgaattacctagagagcttgtattggatacacgaaagaactaaatttggcatcaaacca
ggtgttaaacgtatggaatggatgctagcacaatttaataatcctcaaaataacattaag
ggtattcatgtaggtggcacaaatggtaaaggctctacagttgcttaccttagaacagct
ttagttgaaaatggttatgaagtaggtacatttacgtcgccgtttattgaaacatttaat
gaacgaattagtctaaatggtgtgccaatatcaaatgacgctattgtagaattagtatca
cgtattaaaccagtaagtgaaatgatggaacgtgaaacagatttaggtgttgcaactgaa
ttcgaaataatcacagcgatgatgtttttatattttggtgaaatacatcctgttgatttt
gtcattgttgaggctggattgggtataaagaacgattcgacaaatgtctttacaccggtt
ttatcaatcttaactagtatcggtctagaccatacagatattttaggtggtacttatcta
gatattgctagggataaaggcgcgattataaagcctaacgttccagtgatatatgctgtt
aaaaatgaagatgcattaaaatatgttcgtgaacgcgcaattgaacaacatgcaaagcca
attgaattagatagagaaattgttgttgtatcgcaaaatgatgaatttacttaccgttat
aaagattatgaattagaaacaatcattttaagcatgttaggtgaacatcagaaacaaaat
gctgcattagccataacagctcttattgaattaaatgaacaaggattaattgaattagat
ttcaataagatgatagacggtattgaatcagttcgttggactggacgtattgagcaggtg
catgacaaacctttaatcattttggatggcgcacataattcagagagtatagatgctcta
attgatacaattaaacagtaccatgataaagaaaaagtagatattttgttctcagcaata
aacggaaaaccgattaacgagatggtcaaacatttaagtttaattgcgcatacgttttat
gcaactgaatttgattttccgaaagcgttacgcaaagaagaaattgtaggtagtattgaa
aatgatgaaatacaattagtagatgactacgttgaatttataaaaaattatcaaggtgat
acattagtaattaccggtagtctgtatttcataagtgaagttaaatcaaaattagacttt
gaagcattataa
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