Staphylococcus aureus subsp. aureus USA300_TCH1516 (CA-MRSA): USA300HOU_1273
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Entry
USA300HOU_1273 CDS
T00629
Symbol
thrA
Name
(GenBank) homoserine dehydrogenase
KO
K00003
homoserine dehydrogenase [EC:
1.1.1.3
]
Organism
sax
Staphylococcus aureus subsp. aureus USA300_TCH1516 (CA-MRSA)
Pathway
sax00260
Glycine, serine and threonine metabolism
sax00270
Cysteine and methionine metabolism
sax00300
Lysine biosynthesis
sax01100
Metabolic pathways
sax01110
Biosynthesis of secondary metabolites
sax01120
Microbial metabolism in diverse environments
sax01230
Biosynthesis of amino acids
Module
sax_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
sax_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
sax00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
USA300HOU_1273 (thrA)
00270 Cysteine and methionine metabolism
USA300HOU_1273 (thrA)
00300 Lysine biosynthesis
USA300HOU_1273 (thrA)
Enzymes [BR:
sax01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
USA300HOU_1273 (thrA)
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Motif
Pfam:
Homoserine_dh
HSD_C
NAD_binding_3
Img2
Sacchrp_dh_NADP
DXP_reductoisom
SKA1
Motif
Other DBs
NCBI-ProteinID:
ABX29286
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Position
1357337..1358617
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AA seq
426 aa
AA seq
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MKKLNIALLGLGTVGSGVVKIIEENRQQIQDTLNKDIVIKHILVRDKSKKRPLNISQYHL
TEDVNEILNDDSLDIIVEVMGGIEPTVDWLRTALKNKKHVITANKDLLAVHLKLLEDLAE
ENGVALKFEASVAGGIPIVNAINNGLNANNISKFMGILNGTSNFILSKMTKEQTTFEEAL
DEAKRLGFAEADPTDDVEGVDAARKVVITSYLSFNQVIKLNDVKRRGISGVTLTDINVAD
QLGYKIKLIGKGIYENGKVNASVEPTLIDKKHQLAAVEDEYNAIYVIGDAVGDTMFYGKG
AGSLATGSAVVSDLLNVALFFESDLHTLPPHFELKTDKTREMMDSDAEINIKEKSNFFVV
VNHVKGSIENFENELKAILPFHRSLRVANYDNQSYAAVIVGLESSPEELITKHGYEVDKV
YPVEGV
NT seq
1281 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaaattaaatatagcattattaggattaggtactgtcggatctggtgttgttaaa
atcatcgaagagaaccgacagcaaattcaagatacattaaataaagatattgtcataaag
catattcttgttcgagataaatctaaaaagagaccgctaaatattagccaatatcattta
actgaagatgttaatgaaattttaaatgatgattcattagatattatcgttgaagtcatg
ggaggaattgaaccaactgtagattggttaagaacagcacttaaaaataaaaaacatgtt
attaccgcaaataaagatttattagcagtacatcttaaacttttagaagatttagcagaa
gaaaatggtgtagctttaaagtttgaagcgagtgtagcaggtggtattccgatcgtaaat
gccataaataatggtttgaatgcgaataatatttcaaaatttatgggaattttaaatggt
acctctaattttattttatctaaaatgactaaagagcaaacgacatttgaggaagcactt
gatgaagcgaaaagacttggttttgctgaagcggatccaactgatgatgtagaaggggta
gatgcagcgcgtaaagttgtcattacatcatatttatcatttaaccaagtcattaaatta
aacgacgttaaacgaagaggaattagtggcgtaactttaactgatattaatgtagccgat
caactggggtataaaattaaattgattggtaagggaatatatgaaaatggcaaagttaat
gcatcggtagaaccaacgttaattgataaaaagcatcaattagcagctgtagaggatgaa
tataacgcgatttatgttattggtgatgccgttggtgacacgatgttttatggaaaagga
gcaggcagtttagcaacaggtagtgccgttgtcagtgatttattgaatgtagcattattc
tttgaatcagatttacacacattgccaccacattttgaattaaagacagataaaacacgg
gaaatgatggattcagatgcagaaattaatattaaagaaaaatccaatttctttgtagta
gtgaatcatgtcaaaggttcaattgaaaattttgaaaatgagttaaaggcaatattacca
tttcaccgatcattaagagttgcaaattacgataatcaatcatatgccgctgttatagtt
ggattggaatcatcaccggaagaattaatcactaagcatggatacgaagttgacaaagta
tacccagtagaaggagtttaa
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