Staphylococcus aureus subsp. aureus USA300_TCH1516 (CA-MRSA): USA300HOU_2048
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Entry
USA300HOU_2048 CDS
T00629
Symbol
ilvD
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
sax
Staphylococcus aureus subsp. aureus USA300_TCH1516 (CA-MRSA)
Pathway
sax00290
Valine, leucine and isoleucine biosynthesis
sax00770
Pantothenate and CoA biosynthesis
sax01100
Metabolic pathways
sax01110
Biosynthesis of secondary metabolites
sax01210
2-Oxocarboxylic acid metabolism
sax01230
Biosynthesis of amino acids
Module
sax_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
sax_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
sax00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
USA300HOU_2048 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
USA300HOU_2048 (ilvD)
Enzymes [BR:
sax01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
USA300HOU_2048 (ilvD)
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Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
adh_short_C2
Motif
Other DBs
NCBI-ProteinID:
ABX30045
UniProt:
A8Z4V6
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Position
2165510..2167198
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AA seq
562 aa
AA seq
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MRSDMIKKGDHQAPARSLLHATGALKSPTDMNKPFVAICNSYIDIVPGHVHLRELADIAK
EAIREAGAIPFEFNTIGVDDGIAMGHIGMRYSLPSREIIADAAETVINAHWFDGVFYIPN
CDKITPGMILAAMRTNVPAIFCSGGPMKAGLSAHGKALTLSSMFEAVGAFKEGSISKEEF
LDMEQNACPTCGSCAGMFTANSMNCLMEVLGLTLPYNGTALAVSDQRREMIRQAAFKLVE
NIKNDLKPRDIVTREAIDDAFALDMAMGGSTNTVLHTLAIANEAGIDYDLERINAIAKRT
PYLSKIAPSSSYSMHDVHEAGGVPAIINELMKKDGTLHPDRITVTGKTLRENNEGKEIKN
FDVIHPLDAPYDAQGGLSILFGNIAPKGAVIKVGGVDPSIKTFTGKAICFNSHDEAVEAI
DNRTVRAGHVVVIRYEGPKGGPGMPEMLAPTSSIVGRGLGKDVALITDGRFSGATRGIAV
GHISPEAASGGPIALIEDGDEITIDLTNRTLNVNQPEDVLARRRESLTPFKAKVKTGYLA
RYTALVTSANTGGVMQVPENLI
NT seq
1689 nt
NT seq
+upstream
nt +downstream
nt
atgcgaagcgacatgatcaaaaaaggagatcaccaagcaccagcaagaagtcttttacat
gccacgggcgcgctaaaaagtccaactgatatgaacaaaccatttgtagctatttgtaac
tcttatattgatattgttcctggacatgttcacttgagagagcttgcagatatagctaaa
gaagcaattagagaagccggtgccattccatttgaattcaatacaattggtgttgatgat
ggaatagctatgggacatatcggaatgcgatattctctaccatcacgtgaaattattgca
gatgcagctgaaactgtaattaacgctcattggtttgacggcgtattttacattcctaat
tgtgacaagattacacccggtatgattttagcagccatgaggacaaacgtaccagctatc
ttttgctctggtggaccaatgaaagctggcttatctgcacatggaaaagcattaacactt
tcatcaatgtttgaagcagtcggcgcatttaaagaaggatcgatttctaaagaagaattt
ttagatatggaacaaaatgcctgccctacttgtggttcatgtgctgggatgtttactgca
aattcaatgaactgtttgatggaagttttaggtctaacattaccatacaacggtactgca
cttgcagtcagtgatcagcgacgagaaatgattcgccaagcagcttttaaattagttgaa
aatattaaaaatgatttaaaaccacgtgatatcgttactcgcgaagcaattgatgatgca
tttgcacttgatatggctatgggtggttcaacaaacacggtactgcatacgttagccatt
gccaatgaagctggtattgattatgacttagagcgcattaatgctattgccaaacgcacg
ccatatttatcaaaaatagcacctagttcatcgtattcaatgcatgatgtgcatgaagct
ggtggcgtcccagcaattattaatgaattgatgaagaaagatggcacgttacacccagat
agaatcacagttactggcaaaacgttacgtgaaaataacgaaggcaaagaaattaagaac
tttgatgtcattcaccctcttgatgcaccatatgatgcacaaggcggtttatctatctta
tttggtaatatcgcccctaaaggcgcagttattaaagttggcggcgttgatccatctatc
aaaacatttactgggaaagcaatttgtttcaattcgcatgatgaagctgttgaagcaata
gacaatcgtaccgttcgtgcaggccacgtcgttgtcattagatatgaaggacctaaaggt
ggaccaggtatgcctgaaatgttagcacctacttcctctattgttggtcgcggcttaggt
aaagatgttgcattaattactgatgggcgtttttccggtgccacaagaggtattgcagtt
ggtcatatttcccctgaagctgcatctggtggaccaattgccttaattgaagatggtgat
gagattactattgatttaacaaatcgtacattaaacgtaaaccagcctgaagatgttcta
gcgcgtcgccgagaatctttaacaccatttaaagcgaaagtaaaaacaggttatctagct
cgttatactgccctagtaactagcgcaaatacaggtggcgtcatgcaagtccctgagaat
ttaatttaa
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