Sulfobacillus acidophilus TPY: TPY_2391
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Entry
TPY_2391 CDS
T01576
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
say
Sulfobacillus acidophilus TPY
Pathway
say00290
Valine, leucine and isoleucine biosynthesis
say00620
Pyruvate metabolism
say01100
Metabolic pathways
say01110
Biosynthesis of secondary metabolites
say01210
2-Oxocarboxylic acid metabolism
say01230
Biosynthesis of amino acids
Module
say_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
say00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
TPY_2391 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
TPY_2391 (leuA)
Enzymes [BR:
say01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
TPY_2391 (leuA)
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Gene cluster
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
DUF4148
Motif
Other DBs
NCBI-ProteinID:
AEJ40551
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Position
complement(2222431..2223996)
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AA seq
521 aa
AA seq
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MPRIYLYDTTLRDGTQRAGISLSLEDKIQIAHLLDEFGLDYIEGGWPASNPKDTAFFQAA
RSLPWQSRIAAFGSTRRKEFSATEDPSLNGIVEAGVPVATIFGKASPFQVRDILGIDLDD
NLKMVADSVRYLRDHDIEVVFDAEHFFDGARLDREYAVAVCEAAAEAGAQWVVLCDTNGG
SLPDWIRELTALVGRRISAPLGIHAHDDAGLAVANSLAAVDAGATMVQGTINGYGERCGN
ANLCTIWPNLVFKMGLEAGQKPAMVQELTRLSRTVAEIANLAPDAGAPYVGENAFTHKAG
VHVGAVRKHPEAYEHVPPESVGQKRRVLVSELAGKSNLLYHYEELRPGSAELAQVVEEVK
RLEAQGYQFEDAESSMALLVQRALGQVPEYYQVERFHVSVTRDQAQPVTEATVRLRVGTR
SFLEVGAGDGPVHALDNALRKALTGIYPEVEDLKLTDYKVRVLDGRAATASTVRVLVRSE
FRGQPISTVGVSGNILEASWQALLDAVDYSLWNSGITPMEA
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
gtgccgcggatttatttatatgacaccacgttgcgggatgggacacagcgggctggtatc
agcctttcattagaggataaaatccaaattgcccacttgttggatgagtttgggctggat
tatatcgaaggcgggtggcccgcttccaaccccaaagacaccgcgttttttcaggcggct
cgaagccttccctggcagagccggattgcagcgtttggcagcacgcggcgcaaagagttt
tcggcgaccgaggatcccagcttaaacgggattgttgaggcaggggttccggtcgcgacg
atttttggtaaggcctctccttttcaagtacgagatattctggggattgatttggacgac
aacttgaaaatggtggccgactcggttcgttatttacgcgaccatgatatcgaagtggtg
tttgatgcggaacacttctttgacggggcccgcctcgatcgcgaatatgccgtggcggtt
tgtgaggcggcggcggaagccggcgcccaatgggtggtgctttgtgatacaaatggcggt
agcttgccggactggatccgcgaactgacggctctggtgggtcggcggatttcggctccg
ttgggcattcacgcgcatgacgacgccgggctggcggttgcgaattcgttggcggcggtg
gatgccggggcaaccatggtgcaaggcacgattaacgggtatggcgaacgttgcggcaat
gcgaatttgtgcaccatttggcctaacctggtctttaagatgggcctcgaagccggccag
aaacctgccatggtgcaagaattgacgcgactatcccggacggtggccgagattgccaat
ttggcgcctgacgcgggggccccttatgtgggggagaacgcttttacgcataaggcgggg
gtgcatgtcggggcggtcagaaaacatccggaggcgtatgaacatgtgccgccggaatcg
gtgggccaaaagcgccgggtgttagtgtccgaattagccgggaaatcgaacctgctctac
cactatgaagaattgcggccgggttcggccgaactggcgcaggtagtagaggaagtcaag
cggttggaagcgcaaggctatcaatttgaagatgccgaatcctcgatggctcttttggtc
caacgggctttagggcaagtgcccgaatattatcaagtggaacggtttcacgtgtcggtg
acgcgggatcaggcacaaccggtgacggaagccaccgtgcggctccgagtcggcacccga
tcgtttttggaagtcggggccggtgacggaccggtccatgcattggacaatgccctacga
aaagccttgacgggaatctatcccgaggttgaggatctcaaattgacggactacaaagtg
cgggtactcgatgggcgtgcggcgacggcatcgaccgtccgggtattggtgcgatcggaa
tttcgcggacaaccgattagtacggtgggcgtgtccggcaacattctggaggcgtcctgg
caggcgttactcgatgcagtcgattacagcctgtggaattccggcattacgccgatggaa
gcgtaa
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