Salmonella bongori NCTC 12419: SBG_0001
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Entry
SBG_0001 CDS
T01579
Symbol
thrA
Name
(GenBank) aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
sbg
Salmonella bongori NCTC 12419
Pathway
sbg00260
Glycine, serine and threonine metabolism
sbg00261
Monobactam biosynthesis
sbg00270
Cysteine and methionine metabolism
sbg00300
Lysine biosynthesis
sbg01100
Metabolic pathways
sbg01110
Biosynthesis of secondary metabolites
sbg01120
Microbial metabolism in diverse environments
sbg01230
Biosynthesis of amino acids
Module
sbg_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
sbg_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
sbg_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
sbg00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
SBG_0001 (thrA)
00270 Cysteine and methionine metabolism
SBG_0001 (thrA)
00300 Lysine biosynthesis
SBG_0001 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
SBG_0001 (thrA)
Enzymes [BR:
sbg01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
SBG_0001 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
SBG_0001 (thrA)
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Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
CCC29099
UniProt:
A0A0K0H6V7
LinkDB
All DBs
Position
350..2812
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILENNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LPNISDAERIFADLLTGLADAQPGFPHSQLKSVVEHEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKMSIAIMAGLLEARGHRVTVIDPVEKLLAVGHYLESTVDIAESTRRIAASHIP
DDHLILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGNPQAPGTLIGANSD
EDGLPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFATMSRAGISVVLITQSSSEYSISF
CVPQSDCARAKKAMEDEFYLELKEGLLEPLSIMERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVSNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL
LEQLKRQQTWLKNKHIDLRVCGVANSKALLTNVHGLNLENWQAELAQANAPFNLGRLIRL
VKDYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRFAAEKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELQKFSGILSGSLSFIFGKLDEGMSLSQATALA
REMGYTEPDPRDDLSGMDVARKLLILARETGRELELSDIVIEPVLPGEFDASGDVTAFMA
NLPQLDDAFAARVAKARDEGKVLRYVGNIEEDGVCRVRIAEVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcggagcgctttctgcgtgtt
gccgatattctggaaaacaatgccaggcaagggcaggtagcgaccgtactttccgccccc
gcgaaaattaccaaccatctggtggcgatgattgaaaaaactatcggcggccaggatgct
ttaccgaatatcagcgatgccgaacgtattttcgccgacctgctcacagggcttgccgac
gcgcagccgggattcccgcattcgcagttgaaaagcgtcgttgaacacgaatttgcccaa
attaaacatgttttgcatggtatcagcctgctggggcagtgcccggacagcatcaacgcc
gcgctgatttgtcgtggtgaaaaaatgtcgattgccatcatggcggggctactggaagcg
cgaggacatcgcgtcacggtgatcgatccggttgaaaaattactggcggtgggccattac
cttgaatctaccgtcgatatcgctgaatctacccgccgtatcgccgccagccacatcccc
gacgatcacctgatcctgatggcgggctttactgctggcaacgaaaaaggcgaactggtg
gtgctggggcgtaacggttccgactattccgctgcggtactggccgcctgtttacgcgcc
gactgttgcgaaatctggacggacgttgacggtgtgtatacctgcgacccgcgccaggtg
ccggatgccagactgctgaagtcaatgtcctatcaggaagcgatggaactttcctacttc
ggcgccaaagtgcttcacccgcgtaccattactcccatcgctcaattccagatcccatgt
ctgataaaaaataccggtaatccgcaagcgccgggcacgctgattggcgccaacagcgat
gaagacgggctaccggtaaaaggcatctcgaacctcaataatatggcgatgtttagcgtc
tccggtccgggaatgaaaggcatggtcgggatggcggcgcgcgtgttcgccaccatgtcg
cgtgccgggatttcggtagtgctgatcacccaatcctcttcggagtacagcatcagcttc
tgcgtgccgcaaagcgattgcgctcgcgcgaaaaaggcgatggaagatgaattctacctc
gaactgaaagaagggttactggagccgctctcgatcatggagcgtctggcgatcatttcg
gtggtcggcgacggtatgcgcacgctgcgcggcatttcagcaaaattcttcgccgcgctg
gcgcgtgcgaacatcaatattgtggccatcgcgcagggctcgtctgagcgttctatctcg
gtagtggtcagcaatgacgatgccacgacgggcgttcgtgttacccatcagatgctattt
aataccgaccaggtgattgaagtctttgtcattggcgtcggcggcgtcggcggtgcgcta
ctggagcagcttaaacggcaacaaacctggttgaagaataagcatatcgatcttcgtgtg
tgcggcgtggcgaactcaaaggcgttgttaactaatgtacatggtctgaacctggaaaac
tggcaggcggaactggcgcaagcaaatgcgcccttcaacctgggacgcttaattcgtctg
gtaaaagactatcatctgctcaatccggtcatcgtcgattgtacctccagccaggcagta
gccgaccagtatgctgacttcctgcgtgaaggattccatgttgtgacgccaaacaagaaa
gccaacacctcgtcgatggattattaccatcagctgcgtttcgccgctgagaaatcacga
cgcaaattcctgtatgacaccaacgttggcgccggtttgccggtcatcgaaaacctgcaa
aatctgctgaatgcgggcgatgaactgcagaagttctccggcattctctccgggtcgctc
tcttttatctttggcaaactggacgaggggatgagcctctcacaggcaactgccctggcg
cgcgagatgggctataccgaacccgatccgcgcgacgatctttccggtatggatgtggcg
cgtaaactgttgatcctcgcccgcgagacgggccgcgagctggagctttccgatattgtg
attgaaccggtgttgccgggcgagtttgacgcctccggcgatgtgaccgcctttatggcg
aatctgccgcagcttgacgacgcgtttgccgcccgtgtggcgaaagctcgtgatgaaggt
aaggtattgcgctatgtgggcaatatcgaagaggatggcgtgtgtcgtgtgagaattgct
gaggtggatggtaatgatccgctattcaaagtgaaaaatggcgaaaatgcgctggcattc
tatagccactattatcagccgttgccgctggtgctacgtggttacggcgcaggtaacgat
gtgacggcggcaggtgtgtttgccgatctgctgcgtaccctctcatggaagttaggagtt
taa
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