Shewanella benthica: SHEWBE_1666
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Entry
SHEWBE_1666 CDS
T06707
Symbol
thrA
Name
(GenBank) fused aspartokinase I; homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
sbk
Shewanella benthica
Pathway
sbk00260
Glycine, serine and threonine metabolism
sbk00261
Monobactam biosynthesis
sbk00270
Cysteine and methionine metabolism
sbk00300
Lysine biosynthesis
sbk01100
Metabolic pathways
sbk01110
Biosynthesis of secondary metabolites
sbk01120
Microbial metabolism in diverse environments
sbk01230
Biosynthesis of amino acids
Module
sbk_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
sbk_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
sbk_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
sbk00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
SHEWBE_1666 (thrA)
00270 Cysteine and methionine metabolism
SHEWBE_1666 (thrA)
00300 Lysine biosynthesis
SHEWBE_1666 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
SHEWBE_1666 (thrA)
Enzymes [BR:
sbk01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
SHEWBE_1666 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
SHEWBE_1666 (thrA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
SQH75632
UniProt:
A0A330M063
LinkDB
All DBs
Position
SHEWBE:1548319..1550784
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AA seq
821 aa
AA seq
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MKVMKFGGTSLANWQRFNTAADIVADTAKEEAVAVVLSAPATVTNGLLEMVEAAVSGGDF
TSVLAAVESVFSGLYQEASAVLQASQIDSLMSKLTEQLSFWEDKLLGISLLKECPDFVRA
EILVGGEKLSAALMVQLMKTKGFSSQLLVPQHLLLASGDPLESLVDIESSKARFSQINLD
EHRVWVMPGFTAGDKQGRTVILGRNGSDYSAAVLSACIDASCCEIWTDVDGIYNTDPRVV
SDAKLLSQLSYQEAMELSYFGAKVLHPKTISPIAQYHIPCYIRNSFNPKAPGTLVSNEAD
KSGLNVKAISNLDDQTMFDVSGPGMKGMVGMASRTLGAISRAGISISLITQSSSEYSISF
CINTQDAEKAKDSLELEFELELKSDMLEPIEMRHDLAIVSLIGDGMRTHKGVAGKFFQAL
AQATVNIIAIAQGSSERSISTVIEQRKTKHAISACHQSFFDVQHYLDVFLVGCGNVGAGL
LQQIKQQTEMLKQEHISIRVCGIANSRHMLLDAKGVNLNEWQGLLADSQTQWDIEQMLEW
AKEEQLLNPVLVDCTSSERVSDRYIDVMNAGLHVVTPNKKANTRDIAYYRGLRETALNQR
RQFLYETTVGAGLPVIDNLKKLLFAGDKLLKFNGILSGSLSYIFGMLDEGMSLSEATAIA
RDKCFTEPDPRDDLSGMDVARKVLILAREVGMELELEDIQIESVLPESFDASGDVETFMT
NLPKLDQHIAQRVEKAKSEGKVLRYVGQIDDDGCRVKIAEVDSQDPLYSVKGGENALAFY
SRYYQPIPFVLRGYGAGTDVTAAGVFADLLRTLNWTREMSA
NT seq
2466 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtaatgaagtttggtggtacctcgctggccaattggcaaagatttaacaccgct
gccgacatcgtcgccgatacggcaaaggaagaagcggtagccgtagtgttatcggctccg
gcgacggtgactaacggtttactggagatggttgaagctgccgtgagtggtggagacttt
acctctgttttagccgctgtggagtctgtgtttagcggactctatcaagaagcctctgct
gtactgcaagcgtcacagattgattcactcatgtcgaaactgactgagcagcttagcttt
tgggaagataaactgcttggtatcagcctactcaaggagtgtccggactttgtgagggct
gagattttggtgggtggtgagaagttgtctgcggcgcttatggtgcagctgatgaaaacg
aaaggctttagctcacagctactcgtgcctcaacatttacttttggctagcggagatcct
ctcgaatcactggtcgatatcgagtcgagtaaggcgcgcttcagtcaaattaatttagat
gaacatagggtttgggtgatgccgggctttactgccggcgataagcaagggcgcactgtg
attctaggtcgtaacggctcagactactcagctgcggtattatcagcttgtatcgatgca
tcatgttgtgagatctggaccgacgtcgatgggatctacaataccgatccccgagtggtc
agcgatgctaaattactttcccagctgagttaccaagaggcgatggagttatcctacttt
ggggctaaagtgctgcatcccaagaccatttcccctattgctcagtatcatattccctgt
tatatccgtaatagctttaatcctaaagcgccggggaccttagtttcaaatgaagcagat
aagagtggcttaaatgtcaaagccatctctaatttagacgaccaaaccatgtttgatgtc
tcaggacctgggatgaaaggcatggtgggcatggcgagtcgcaccttaggggctatctct
cgagccggaatttcaatttcattgatcacccaaagctcatctgaatacagcatcagcttc
tgtatcaatactcaagatgcagaaaaagccaaggattcattagagcttgagtttgaactg
gaacttaagagtgacatgctagagcctatcgagatgcgccatgatttagccattgtgtcg
ctcataggtgacggcatgcgcacccataaaggcgtagccggtaaattcttccaggctctt
gctcaggccacggtgaacatcattgctatcgctcagggctcctctgagcgatctatctca
accgtaatagagcagcgcaagactaagcatgccatcagtgcctgtcatcagagcttcttc
gatgttcagcattatctggatgtattcctcgtgggctgtggcaatgtaggcgccgggttg
ctgcaacagattaagcaacaaacagagatgttaaagcaggagcatattagtatcagggta
tgcggaattgccaactctcgtcatatgctactcgatgccaaaggcgttaatcttaacgag
tggcaggggctactcgcagacagtcagactcaatgggatattgagcagatgcttgaatgg
gccaaagaggagcagctgttaaacccggttttggtcgactgtacttcaagcgagcgcgta
tcagatcgctatatcgatgttatgaatgcgggtttgcacgtggtaacgcccaataagaaa
gcgaatacccgagatatcgcttattaccgtggactgcgtgaaaccgctcttaatcagcgt
agacagtttttatatgaaacgacggtcggtgccgggctgcctgttatcgataacttgaag
aagctcctgtttgccggcgacaaattgctcaagtttaatggcatattatccggctctctt
tcatacatcttcggcatgttagatgaggggatgtctttgtctgaggcgacggcaattgcc
agagataaatgtttcacagagcctgatcctcgtgacgatcttagtggcatggatgtcgcc
aggaaagtactcatattggctcgtgaagtcggcatggaactggagctggaagatattcag
atagagtctgtattacctgagtcattcgatgccagcggcgatgtggaaacctttatgact
aatctacctaagttggatcagcatatcgcccaacgggttgaaaaagccaagagtgaaggc
aaggtactacgctatgtcggccagatagatgatgacggttgccgggttaaaatagccgaa
gtggactctcaagaccccttatatagcgtaaaaggaggtgagaatgccttggctttctac
agccgttattatcagcccattcccttcgtactcagaggatatggtgcggggactgacgtg
accgcggctggcgtctttgccgatcttctccgcacactgaactggacgcgggagatgagt
gcatga
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