Streptomyces boninensis: ACNNMR_36215 Help Entry ACNNMR_36215      CDS       T11867                                  Name (GenBank) type I polyketide synthase Organism sbon  Streptomyces boninensis SSDB OrthologParalogGFIT Other DBs NCBI-ProteinID:  XQA00683 LinkDB All DBs Position 7961331..7988738 Genome browser AA seq 9135 aa AA seqDB search MADNEKLLETLKKLAADHYVTRERVKELESGAREPIAIVGMGCRYPGDVRGPEQFWELLT AGTDTLSGFPTDRGWEAFEEEFGGEAAQSDGAYVREGGFLYDVADFDAGFFGINPREALA MDPQQRLLLETVWEAIERAGLAPSSLHGSATGVFIGASGSGYETILPPDDKSLDGYRLTG TVSSVISGRISYVLGLTGPAVTVDTACSSSLVALHQAVTALRGGECTMALAGGVAVMTSP GAFMEFSEQGGMASSGRCKAFSDEADGIGWGEGSGVLLLERLSDAQRNGHQVLAVIRGSA VNQDGASNGLSAPNGPSQRRVIRAALANAQLAAGEVDAVEAHGTGTSLGDPIEAGALLAT YGQERSDERPLWLGSVKSNIGHLQCAAGVAGVIKMVLSLQHSQLPRTLYADAPSTQIDWS AGNVRLLQEAREWPAAEQPRRAGVSAFGVSGTNVHVILEEAPAAVEEPESAGEGEPELPV FAPAVPAWAVSGHSAGALAGQAGRLREHVVGRPGIPVADVAWSLATSRSVFEHRAVVLGA EREELLAGLASVATQQPAAGVVTGEVAPGGIGRTVFVFPGQGSQWMGMGRELAESSPVFA AKLAECAAALAPYVQWELDDVLAGRHGFEAADVVQPALWAVMVSLAAVWQAAGVEPDAVV GHSQGEIAAAAVAGILSLEDAAKVVALRSRALTVLAGRGGMLSVAEHVAAVRERIAGFGD RVSIAAVNGPSATVVSGEPDALRELQEACGESVRTRLIPVDYASHSPQVDDLRDAILAAL DGIAPGEARIPMVSAMSGEWLAGPEMDAGYWYASLREPVEFDQAIRVLGQAGHGVFVEAS PHPVLIQAIADSLDERSPITVGSLRRDDGGSQRLLASLAEAFVRGVVVDWTAVLGGGDTI DLPTYAFQRRRFWPEIREIKRAARSIDDWRYRITWQPSDLNGVPALSGTWLLVGDDPEAP AIAEALTGHGADVVTAMSVEDLEASALAEAAGVVSLLALDETPDAEFPWISRGIAATVEL VQAVQQAGAEVAVWTLTRGAVQTGAGEVTTSPSQTAVWGLGRAVGLERPELWGGLIDLPT EFTDRTGTHLASVLAQTSEDQIALRAEGVFLRRLVRAEARRAQSKPWSPRGTVLLTGGTG SIGVSIGSWLADHDTSRVVLTSRSGPSAPGVPALAAAVAAGGTDVEVVSCDLQAYEQVSG MVSWIEASGPGLSTVLHSANQPYLAWVENTEREGLAAALGAKAVGALHLDQATTDLDLDE FVLFSSISATWGSNDHGAYAAGNAFLDGFAEDRRSRGLPATSIAWGVWDTRDWDAVDAAM TQGAGAVTPSRLRRQGMNFLDTDRALTALGEILTEDETFIAVADVEWERFAPVFRAARPR PLLDTIPEAREDDQPASHAESAASGLGEYASLLAAMSVSERRRTVIELVRSHATAVLGHD STDAIPAERAFRDVGYDSLTAVELRNRLNTATGVRLPSTVVFDHPNPTALAEEILTRLLG TASQQAASVVVQAPTEPIAIVGMGCRYPGGVSSPEEMWELLAAKGDAISDFPADRGWDAE ALFDPDPDAEGSTYVTEGGFITGAGNFDADFFGISPREALAMDPQQRLLLETSWEAIERA GIDPTSLKGSGTGVFVGAAASGYIAVASGDPETEAHLITGNALSVLSGRISYTLGLVGPS VSVDTACSSSLVALHQAVTALRGGECTMALAGGVMVMADPGEFVGFSRLRVLASDGRCKA FGEGADGMGIAEGAGMVMLERLSDAQRNGHQVLAVIRGSAVNQDGASNGLSAPNGPSQQR VIRAALANAQLTPADVDVVEAHGTGTALGDPIEAGALQATYGDERPDEDRPLWIGSVKSN IGHAQQAAGVAGLIKMVMSLQHGQLPQTLYAETPSSHVDWSAGNVRLLQEAREWAAGEQP RRAGVSAFGISGTNAHVILEEAPVAVEEPEPVPEAGEAPALPVLAPAVPAWLVSGRGATA LASQAGRLREHVVTRAELSADDVAWSLATTRSALDHRAVVLGTERDGLLAGLAALATDQP AAGVVTGEVAPGGIGRTVFVFPGHGSQWIGMGRELAEASPVFAAKLAECAAALRPYVDWE LNDVLAGRHDFAAADVLQPAVWAVTVSLAAVWQAAGVEPDAVVGHSLGEIAAATVAGVLS VADGAKVAGLRAKALRTLDGRGGMLSVGEPADVVRDRLAGFGERLSVAAVNGPSSTVLSG ANDALDEFVAACPEGVRTSRIPIAYASHSAQVEELREQILTALADVVPGAARVPMLSAMS GEWLAGPEMDAGYWYASLREPVEFGRAVRVLGESGHGVFVETSAHPALIQAITSNLEDRD LVAVGTLRRDNGGAERLLASLAEAYVRGVPVEWAAVLGGGGSAVELPTYAFQHRHYWPRA VEQAATGAAGGSTPAEAGFWAAVEEGDAGSLAELLGVDAGEIDLAALTEWRRRERADATV ADWRYRVTWMPVAESAGVLSGRWLVVGDGAEAEAVGAVLAERGAEVVAVAGPEQVAAASD IADVTGVVSALALSDAEHPEFPVVPAGLMATVELLRALGGAGVSAPLWVLTRGAVGTGAG DPVVNLTQAEVWGLGVTAGLELAGRWGGLIDLPAVLDARAGGRLVSMLADGGEDQVAIRA GGVVGRRLEHAPRPVVRQAWAPRGSVLVTGGTSGVGAITAGWVVERGAARVVLTSRSGPR AGGVAGLAAALSQSGAAVEVVACDAADRGSVAGLVEWIDASGAELSSVVHAAGLGDGGPV EEVEAADLARLLSAKAGGAAVLDELTADRDLDAFVMFSSGAAAWGSGGLSAYAAANAYLD ALGDSRRARGLAATSIAWGVWAGVGMAASEGGERLLAYGMEGIDAERGMRILGQALDADE SSLAVAGFTWEQFVPTYTLYRPSPFLSGVPEVRDVLAAEAEGEAGGEADARGSELAVRLR GMAEGEQRQLLTDMVRGHAAVVLGHASAEDVLPQRAFKDLGFDSVGAVELRNRLAAAAGV RLPSTLIFDYPNAAALAEYICGELVGSDAASAEGAVRVVAAAGGEPIAIVGMGCRYPGDV RGPEQLWDLVASGTDAISPFPTDRGWEAFEEEFGGEEALSGRSYVREGGFVYDAAKFDAD FFGISPREALAMDPQQRLLLETSWEAIERAGLAPSALHGSATGVFIGASGSGYESSLPVH DQSLDGYRLTGSVSSVASGRISYVLGLTGPAVTVDTACSSSLVALHQAVSALRGGECTMA LAGGVAVMTSPGAFMEFSKQGGMASSGRCKAFSDGADGIVWGEGAGMVVLERLSDARRNG HPVLAVIRGSAVNQDGASNGLSAPNGPSQRRVIRAALANAQVSAADVDVVEAHGTGTSLG DPIEAGALLATYGQERPDDDRPLWLGSVKSNIGHAQQAAGVAGVIKMVLAMRHGVLPRTL HAGDPSSHVEWSTGNVRLLQEAREWPAGEQPRRAGVSAFGISGTNVHLVLEEAPGSVEEP EPVPETVDAPGLPVFEPAVPAWVVSGRSAVALAGQAGRLREHVVGRPAVPVGDVAWSLAT SRSVFEHRGVVLGAEREELVAGLAAVATDQPAAGVVTGEVSPVGVGRTVFVFPGQGSQWV GMGRELAESSPVFAARLAECAAALEPFVDWELDDVLAGRHGFEAADVVQPALWAVMVSLA AVWQAAGVEPEAVVGHSQGEIAAAAVAGILSLEDAAKVVALRSRALTALAGRGGMLSIAE PVAAVRERIAAFGDRLSIAAVNGPSATVVSGEPDALRELADSCGESVRTRLIPVDYASHS PQVDELRDDILAALDGITPGETRVPMVSAMSGEMLAGPEMDAGYWYASLREPVEFDQAIR VLGEAGHGVFVEASPHPVLIQAISDSLDEKAPVAVGSLRRDDGGTERLLTSFAEAFVRGV AVDWTAVLGAGDTVELPTYAFQERHFWPETRAAEVLGVSEGDAEFWAAIEGGDLEELAAT LNVDGDRLAEMVPVLAEYRRRSQVDAAVADWRYRVRWTPVAEAGSVLSGRWLVVGDGADA EAVSAVLAERGAEVVVVAGPEQVAASDVADVAGVVSALALSDATHPEYPVVPAGLMATVE LIRALGAAGVSAPLWVLTRGAVGTGASDPVVSPVQAQVWGLGVTAGLELVGRWGGLIDLP AVWDARAGGRLVSVLAGGGEDQVAIRTGGVLGRRLEHAPRAAVGETWAPRGSVLVTGGTS GVGAITAGWVAERGAPRVVLTSRSGPAAAGVAGLAAAMAQTGAAVEVAACDIADRGSVTG LLEWIDASGAELSSVLHAAGVAGGGPVEEVEAAELARLLAAKAGGAALLDELTADRELDA FVLFSSGAGTWGSGGLSAYAAANAYLDGLCDSRRGRGLAATSVAWGLWAGVGMVAGGDGA RLSDFGMAGIDAERGMRALGQVLDAGEGALAFAGFDWEQFVPTYTLYRPSPLLSGLPEVK DVLEATEEVAAAADGSELGVRLRGMSVGDQRQELTQLVRGHAAAVLGHESAEDVLPQRAF KDLGFDSVGAVELRNRLVSAVGVRLPSTLVFDYPNAAALAEFIRGELVGSAEAAPGDGGV QVVAAAGGEPIAIVGMGCRLPGDVRGPEQFWELLTAGTDAVSGFPTDRGWEAFEEEYGSE AVRTGRSYVREGGFLYDAADFDAGFFGINPREALAMDPQQRLLLETSWEAIERAGLAPSS LHGSATGVFIGATYSGYEGNLPTHDESLDGYRLTGMISSVASGRISYALGLTGPAVTVDT ACSSSLVALHQAVTALRGGECTMALAGGVAVMTSPGAFMEFSEQGGMASSGRCKAFSDEA DGIGWGEGAGVLLLERLSDARRNGHQVLAVVRGSAANQDGASNGLSAPNGPSQRRVIRAA LANAQVSAADVDVVETHGTGTSLGDPIEAGALLATYGQERPGAERPLWIGSVKSNIGHLQ CAAGVAGVIKMVLSLQHGQLPRTLYAETPSTQVDWAAGDVRLLQEAREWPAGEQPRRAGV SAFGISGTNVHVILEETPAEAGEPEPAGEGEPELPVFASAVPAWVVSGHSAAALAGQAGR LREHVVGRPGIPVADVAWSLATSRSVFEHRAVVLGGEREKLLAGLASVAMQQPAAGVVSG EVAPGGIGRTVFVFPGQGSQWVGMGRELAESSPLFAARLAECAQALAPYVEWELDDVLAG RHGFEAADVVQPALWAVMVSLAAVWQAAGVEPDAVVGHSQGEIAAAAVAGILSLDDAARV VALRSRALTVLAGRGGMLSVAEPVAAVRERIASYGERLSIAAVNGPSATVVSGEPEALRE LVDSCGESVRTRLIPVDYASHSPQVDDLRDDILAALAGITPSEPRIPMISAMTGEMISGP EMDAGYWYASLREPVEFDRAIRALGEAGHGVFVETSPHPVLIQAIADSLQDRDPITVGSL RRDDGGTERLLASLSEAFVGGVPVDWTAVLGGGDTIDLPTYAFQRRRFWPEVAAPQRKSV DDWRYRITWQQSDLGGGVPALSGTWLLVGDDPDAPAIAEALTGHGAEVVTVPAPAELDPS ALAEAAGVVSLLALDETPDASYPWVPSGTATTLDLVHALHQSGTAAPVWVLTRGAVQTGA GEVTTSPSQTAVWGLGRAVGLEHPGLWGGLIDLPTAFDGRAGMGLVSVLAQPSEDQVALR AEGVFLRRLVRAEARRAEAGRWTPRGTVLLTGGTGSIGASVGGWLAEHDTSRVVLTSRSG PSAPGVPALAASVAAGGTAVEVVSCDLGVPEQVSGMVSWIETSGPGLSTVLHSANQPYLA RVEDTERDGLAAALGAKAAGAVHLDQATAGLDVDEFVLFSSISATWGSNDHGAYAASNSF LDGLAEQRRSRGLPATSIAWGVWDTRDWDAVDASMKQGPGAVTPSRLRRQGMNFLDTDRA LTALGEVLADDETFIAVADVEWERFAPVFRAVRPRPLLDTIPEAQEELGPIGSVETAVAG RGEYASRLAGMAAGERRRTVVDLVRSHATAVLGHASVDEIPAERAFRDVGFDSLTAVELR NRLNAAAGVRLPSTVVFDHPNPAALAEEILTGLFGVESGAERGVTVAAAAPSEPIAIVGM GCRYPGGVRSPEELWALLASGGDAISGFPVDRGWDAEALFDPDPDAEGSTYVMEGGFITG AGHFDADFFGISPREALAMDPQQRLLLETSWEAIERAGIDPGSLKGSGTGVFVGGTTSGY VGSAMDTAGAETHLITGNALSVLSGRISYSLGLVGPAVSVDTACSSSLVALHQAAQALRS GECTMALAGGVMVMADPSEFVGFSRLRALSSDGRCRAFGDGADGMGIAEGAGMVMLERLS DARRNGHPVLAVIRGSAVNQDGASNGLSAPNGPSQRRVIRAALANAQVSAADVDVVEAHG TGTELGDPIEAGALLATYGQERPDADRPLWIGSIKSNIGHAQQAAGVAGLIKMVMSLQHG QLPQTLYADTPSSHVEWSTGNVRLLQEAREWAAGERPRRAGVSAFGISGTNAHLILEEAP GTVEEADSELEPAGEGQLGLPVFAPSLPAWVVSGRSAVALAEQAGRLREHVVGRPGLPVG DVAWSLATSRSVFEHRAVVLGGEREELLAGLAAVATDQPAAGVVSGETASGTAGGTVFVF PGQGSQWVGMGRELAASSPVFAARLAECARALAPYVEWELDDVLAGRHGFEAADVVQPAL WAVMVSLAAVWQAAGVQPDAVVGHSQGEIAAAAVAGILSLDDAAKVVALRSRTLAALAGR GGMLSIAEPVAAVRERIAAFGDRLSIAAVNGPSATVVSGEPDALRELADSCGESVRTRLI PVDYASHSPQVDELCEDILAALDGITPSETRIPMISAMTGDMISGPDMDAGYWYASLREP VEFDRAIRTLGESGHGVFVEASPHPVLIQAISDSLYEKAPVAVGSLRRDDGGTERLLASL SEAFVRGVAVDWTAVLGGGETVDLPTYAFQERHYWPEARPVEVPEVSAGDAEFWAAVEGG DLEELAATLNVDGAGIAEIVPVLAEYRRRSQADATVADWRYRVTWAPVVESAAVLSGRWL VVGDGADAEAVSAVLAERGAEVVAVADLGRLAAFDAADVAGVVSALAVSDAAHPEHEVVP AGLVATVELVRALGAAGVSAPLWVLTRGAVGTGASDPVISPVQAQIWGLGVVAGLELAGR WGGLIDLPEVWDARAGGRLVSVLADGGEDQVAIRAGGVLGRRLEHAPRPAIGEAWAPRGS VLVTGGTSGVGAITAGWVAERGAARAVLTSRSGAAAAGVAGLAASIATAGTAVEVVACDI AERGSVAGLLEWIDADGPVLSSVMHAAGVGDRRPVAELEAAELAYVLAAKAGGAALLDEL TAGRELDAFVLFSSGAGTWGSGGLSGYAAANAYLDALCDSRRARGLVATSIAWGLWAGVG MAAVGGSGERLLDFGMAGIDAERGMRALGQALDAGEGVLAVAGFDWPKFVPTYTLHRASP FLSGLPEVRAVLAAEADPTDGAAGDPSASELAIRLRGMGEGEQRQELTQLVRGHAAAVLG HASAEDVLPQRAFKDLGFDSVGAVELRNRLANAAGVRLPSTLVFDYPNAVTLAEFIRGEL VGSDSASAEGAVRVVAAAGGEPIAIVGMGCRYPGDVRGPEQFWELLTNGTDAISGFPTDR GWESVEEEFDGKAARSGRSYVREGGFVYDVADFDPGFFGINPREALAMDPQQRLLLETSW EAIERAGLAPSSLHGSATGVFIGATGSGYDNALPHDDQSLDGYRLIGTVSAVASGRISYV LGLTGPAVTVDTACSSSLVALHQAVSALRGGECTMALAGGVAVMTSPGAFMEFSEQGGMA SSGRSKAFSDEADGIGWGEGAGVLLLERLSDAERNGHQVLAVIRGSAVNQDGASNGLSAP NGPSQRRVIRAALANAQVSAADVDVVETHGTGTSLGDPIEAGALLATYGQERPGDDRPLW IGSVKSNIGHLQTAAGVAGVIKMVLSLQHSQLPRTLHAETPSTQIDWTAGNVQLLQEQRE WLPNGRPRRAGVSAFGVSGTNAHVILEEAPVAVEEPEPVSETVDAPVLPVLARAVPAWVV SGRSAVALAGQAGRLREHVVGRPGIPVGDVAWSLATSRSIFEHRAVVLGAEREELLAGLA AVATDQPAAGVVTGEVSPVGVGRTVFVFPGQGSQWVGMGRELAESSPVFAAKLAECAAAL APYVDWELDDVLAGQHGFEAADVVQPALWAVMVSLAAVWQAAGVQPDAVVGHSQGEIAAA AVAGILSLDDAAKVVALRSRTLAALAGRGGMLSIAEPVAAVRERIASFGERLSIAAVNGP SATVVSGEPDALRELQDGCGESVRTRLIPVDYASHSPQVDQLRDDILAALDGIAPGEARI PMVSAMSGEWLTGPEMDAGYWYASLREPVEFDQAIRVLGEAGHGVFVEASPHPVLIQAIA DSLDEASPITVGSLRRDDGGTERLLTSLSEAFVGGVPVDWTAVLGGGATVELPTYAFQRR RFWPEVPAAQRKSMDDWRYQITWQQSDLGGLSALSGTWLLVGDDREALAIAEALAGHGAD VVTVAGPDELTPSALADAAGVVSLLALDETPDAEFPWISRGIAATVELVQAVQQAGAEVA VWTLTRGAVQTGAGEVTTSPSQTAVWGLGRAVGLERPELWGGLIDLPTEFTDRTGTHLAS VLAQTSEDQVALRTEGVFLRRLVRVEARRAQAGRWSPRGTVLLTGGTGSIGVSIGGWLAD HDTSRVVLTSRSGPSAPGVPALAASIAAGGTDVEVLSCDLQTLEQVSGMVSWIEASGPGL STVLHSANQPYLAWVENTEREGLAAALGAKAVGAVHLDQATAGLDVDEFVLFSSISATWG SNDHGAYAAGNSFLDGFAEDRRSRGLPATSIAWGVWDTRDWDAVDAAMTQGAGAVTPSRL RRQGMNFLDTDRALTALGEILTEDETFIAVADVEWQKFAPVFRMARPRPLLDTIPEAQDD PAPAASTGAGDDGYSEYAARLAALSEAERRRTVIELVRSHATAVLGHDSTDEIDAARAFR DVGFDSLTAVELRNRLNAAAGVRLPSTVVFDHPNPTALAEEILTQLFENELVGHTAVLDE FERLAAGLTPSDEAARTEIVARLEALTQRFRALRSEQGTAGGVVDEAEQQRALEEATADE LFALLEDELDDPDLD NT seq 27408 nt NT seq  +upstreamnt  +downstreamnt gtggctgacaacgagaagttgctcgagactctgaagaagttggcggccgatcattacgtg acccgcgaacgggtcaaggagctggaatccggcgcccgtgaacccatcgcgatcgtgggt atgggctgccgttaccccggtgacgtccgtggacccgagcagttctgggaactgctcacc gccggtacggacacgctgtccggattcccgaccgatcgtggatgggaagcgttcgaggag gaattcggcggcgaggcggcgcagtcggatggcgcttatgtgcgcgagggcggcttcctc tatgacgtagccgattttgacgcgggcttcttcgggatcaatccgcgtgaggcgctggcg atggatccgcagcagcggctgctgctggagaccgtgtgggaggcgattgagcgggcgggg ctggctccgtcgtcgctgcacggctcggcgaccggtgtcttcatcggcgcgagcggttcc ggctacgagaccatcctgcctcccgacgacaagagcctggacggctaccggctcaccggc acggtctcctcggtgatctcggggcggatctcgtacgtgctggggctgaccgggcctgcg gtgacggtggacacggcgtgctcgtcgtcgctggtggcgctgcaccaggcggttacggcg ctgcgtggtggcgagtgcacgatggcgctggccggtggcgtggccgtgatgacctcgccg ggcgccttcatggagttttccgagcagggcgggatggcctccagcgggcgctgcaaggcg ttctcggatgaggccgatggcatcggctggggcgaaggctccggtgtgctgctgctggag cggctgtcggatgcgcaacgcaatggccaccaggtgctggccgtcatccgcggcagcgcg gtcaaccaggatggtgcgtcgaacggcctgtccgcgcccaatggcccctcgcagcggcgc gtgatccgggcggcgctggcgaatgcgcagctggctgccggtgaggtggacgcggttgag gcgcacggtacggggacatcgctcggtgacccgatcgaggccggggcgctgctggcgacg tacgggcaggaacgctccgacgaacggccgttgtggctggggtcggtgaagtccaacatc gggcatctgcagtgtgctgccggtgtggccggtgtgatcaagatggtgctgtcgctgcag cacagccagttgccgcggacgctgtacgcggatgcgccgtccacgcagatcgactggtcg gccgggaacgtacgccttcttcaggaggcgcgggagtggccggctgctgagcagcccagg cgggccggtgtctcggctttcggcgtcagcggcacgaatgtgcatgtgatcttggaggag gcgccggcggcggtcgaggagccggagtctgcgggtgagggcgagccagagctgccggtg ttcgcgcctgcggttccggcttgggcggtttcggggcatagcgcgggcgcgcttgccggg caggctgggcggctgcgtgagcatgtcgtgggtcggcctgggatcccggtggcggatgtg gcgtggtcgttggctacgtcgcggtcggtcttcgagcaccgtgccgtagtgctgggggct gagcgggaggaactgctggcggggctggcgtccgtagccacgcagcagcctgctgccggt gtggtgaccggtgaggtggcgcctggcgggatcggccggaccgtatttgtcttccccggt cagggctcgcagtggatggggatgggccgggaactggccgagtcctcgcccgtcttcgcg gcgaagctcgccgagtgcgcggcggcgctggctccgtacgtgcagtgggagctggatgac gttcttgctggtcggcatgggttcgaggctgcggatgtggtgcagcctgccctctgggcg gtgatggtctcgctcgccgcagtgtggcaggccgccggcgtcgagccggatgcggtcgtc ggccactcccagggtgagatcgcggctgctgcggtggccgggatcctgtcgctggaggac gcggccaaggtggtcgcgctgcgcagccgtgccctgaccgtgctggccgggcggggcggc atgctgtccgtcgccgaacacgtcgcggccgtacgggagcggatcgccgggttcggtgac cgggtgtcgatcgctgctgtgaacggcccgtcggcgaccgtggtttccggtgagccggac gcgctgcgcgaactccaggaagcgtgcggggagtcggtgcggacacgcctgattccggtg gactacgcctcccacagcccgcaggtggacgacctccgcgacgccatcctggcggcgctg gacgggatcgctcccggcgaggcgcgcatcccgatggtctcggcgatgagcggcgagtgg ctggccgggccggagatggacgcggggtactggtatgcctcgctgcgggagcccgtcgag ttcgaccaggccatccgcgtcctcggtcaggccggccacggcgtgttcgtagaggcctcc ccgcatccggtgctgatccaggccatcgccgacagcctggacgagaggtcgccgatcacc gtaggcagcctccgccgcgacgacggcggttcccagcggctgctcgcctccctcgctgag gcgttcgtacgtggtgtggtcgtcgactggaccgcggtgctgggtggcggggacaccatc gacctgccgacgtatgccttccagcggcgccgcttctggcccgagatacgtgagatcaag cgggccgcccggtcgatagatgactggcgctatcgcatcacctggcagccgtccgacctc aacggggttcccgcgctgtccgggacctggctgctggtcggagacgatccggaggcgccc gcgatcgcggaggcgctgaccggacacggcgccgacgtcgtcaccgccatgagcgtcgag gacctcgaggcctccgcgctcgcggaagccgcgggtgtggtgtccctgctggccctggac gagacgccggatgcggagttcccgtggatctcgcgtggcatcgccgcgacggtcgagctg gtccaggcggtgcagcaggccggggccgaggttgcggtgtggacgctgacccgcggcgcg gtgcagaccggcgcgggcgaggtgacgaccagcccgtcccagaccgcggtctggggcctg ggtcgcgcggttggccttgagcgtcccgagctgtggggcggcctcatcgacctgcccacc gagttcaccgaccgaacaggcacccacctcgcatccgtcctggcacaaaccagcgaggac cagatcgctttgcgcgccgaaggcgtcttcctgcgccggctggtacgggccgaggcacgc cgcgcccagtccaagccgtggtccccgcggggcacggtcctgctgaccggtggcaccggc tcgatcggcgtcagcatcggtagctggctcgccgatcacgacacctcgcgggtggtgctg acctcccgttccggcccgtccgctcccggcgtacccgccctcgcagcagcggtcgccgcc ggcggcacggacgtcgaggtcgtcagctgcgacctgcaggcgtacgagcaggtctccggc atggtgtcctggatcgaagcatccggacccggcctctcgaccgtcctgcactcggcgaat cagccctatctcgcctgggtggaaaacaccgaacgcgaaggcctggccgccgcactcggc gccaaagcagtcggcgcgctccacctggaccaggccaccaccgaccttgacctcgacgag ttcgtgctgttctcctcgatctcagcgacctggggcagcaacgaccacggcgcctacgcc gcaggcaacgccttcctcgacggcttcgccgaggaccgccgctcccgcggtctccccgcg acatccatcgcctggggggtctgggacacccgcgactgggacgccgtagacgcggccatg acccagggcgcaggggcagtcacccccagccgcctccgccgccagggcatgaacttcctc gacaccgaccgcgccctgaccgccctcggcgaaatcctcaccgaggacgagaccttcatc gccgtcgccgacgtcgaatgggagcgattcgcccccgtcttccgcgccgcccgcccccgc cccctcctggacaccatccccgaagcgcgcgaggacgaccagcccgcaagccacgccgag tcggcggcctccgggctcggcgagtacgcctcccttctcgccgcgatgtccgtgagcgag cgtcgccgtacggtcatcgagctggtccgctcccacgccaccgccgtcctgggccacgac tccacggacgcgataccggccgagcgcgccttccgcgacgtcggatacgactcgctcacc gcggtcgagctccgtaaccgcctcaacaccgccaccggagtccggctgccgtccaccgtg gtcttcgaccaccccaaccccacggccctggccgaggagatcctcaccaggctgctgggc accgcatcgcagcaggccgcctccgtcgtggtgcaggcgccgaccgagccgatcgccatc gtcggcatgggctgccgctatccgggcggggtgagcagccccgaggagatgtgggagctg ctggctgcgaagggtgacgccatctcggacttcccggccgatcgtggctgggacgccgag gcgctgttcgacccggacccggacgccgagggttccacctatgtgaccgagggcggcttc atcaccggagccgggaacttcgacgcggacttcttcggcatcagcccgcgcgaggcgctc gcgatggacccgcagcagcggctgctgctggagacgtcgtgggaggccatcgagcgggcg ggcatcgacccgacctcgctgaagggctcgggcaccggtgtcttcgtcggcgccgcggca tccggctatatcgccgtggccagcggagatccggagaccgaggcgcatctgatcaccggc aacgcgctgagcgtgctgtccgggcggatctcctacaccctgggactggtcggcccgtcc gtatccgtcgatacggcctgctcctcctccctcgtggcgctgcaccaggccgtgaccgcg ctgcgcggtggcgagtgcaccatggcgctggccggcggtgtgatggtgatggccgacccg ggtgagttcgtcggcttctcgcggctgcgcgtgctggcatcggacgggcggtgcaaggcc ttcggcgaaggcgccgacggcatgggcatcgccgagggcgccggcatggtgatgctggaa cggctctccgacgcgcagcgcaacggccaccaggtgctggccgtcatccgcggcagcgcc gtgaaccaggacggcgcctccaacggcctgtccgcccccaacggcccctcccagcagcgc gtcatccgcgccgccctggccaacgcgcagctcacgcccgccgacgtcgacgtcgtcgag gcacacggcacgggcaccgccctgggcgacccgatcgaggccggcgccctccaggccacg tacggcgacgaacggccggacgaggaccggccgctgtggatcggctcggtcaagtcgaac atcgggcacgcgcagcaggcggccggtgttgccgggctcatcaagatggtgatgtccctc cagcacgggcagctgccgcagacgctgtacgcggagacgccgtcgtcgcatgtcgactgg tcggccgggaacgtacgccttctgcaggaggcgcgggagtgggcggccggtgagcagccc aggcgcgcgggtgtctccgccttcgggatcagcggcaccaacgcgcacgtcatcctcgaa gaggcgccggtcgccgtcgaggagccggagcctgttcccgaggctggggaggccccggcg ctgccggtgctcgcgcccgccgttccggcgtggctggtgtcgggccgcggcgcgaccgcg ctggcgagccaggccggccgccttcgcgaacatgtcgtgacccgcgcggagctgtcggcg gatgacgtggcgtggtcgcttgccacgacccggtcggcgctggaccaccgcgccgtagtc ctcggtaccgagcgcgacggcctcctcgccggactggccgcgctggccaccgaccagccg gccgccggggtggtgaccggagaggtcgcgcccggcggcatcggccggaccgtcttcgtc ttccccggccacggcagccagtggatcgggatgggccgggagctggccgaagcctcgccc gtcttcgcggcgaagctcgccgagtgcgcggcggccctccggccgtacgtcgactgggag ctgaacgatgtcctggccggaaggcacgacttcgccgccgccgacgtgctgcagccggcc gtatgggcggtgaccgtatccctggccgccgtctggcaggccgccggcgtcgagccggac gccgtcgtcgggcactcgctcggcgagatcgccgcggcgaccgtggccggggtgctgtcg gtcgcggacggcgcgaaggtggccggcctgcgggccaaggcgctgcggaccctggacggc cgcggcgggatgctgtccgtcggcgagcccgccgacgtggtacgggaccggctcgccggc ttcggcgagcggctctcggtcgcggccgtcaacggcccctcgtcgacggtgctttccggc gccaacgacgccctggacgaattcgtcgccgcctgccccgaaggcgtacggacctcgcgt atcccgatcgcctacgcctcgcacagcgcgcaggtggaagagctgcgcgagcagatcctc accgccctggcggacgtcgtgccgggtgcggcacgggtgccgatgctgtcggcgatgagc ggggagtggctggccgggccggagatggacgcggggtactggtatgcctcgctgcgggag ccggtggagttcggccgggcggtccgggtgctgggggagtcggggcacggcgtcttcgtg gagacgtctgcgcacccggcgttgatccaggccatcacctccaacctggaggaccgtgac ctggtcgcggtgggcacgctcaggcgggacaacgggggtgccgagcggctgttggcctcc ctcgccgaggcgtatgtgcggggtgttcccgtggagtgggccgcggtgctgggtggtggc gggtcggcggtggagctgccgacgtatgccttccagcaccggcactactggccgcgggcg gtcgagcaggcggcgacgggggcggcgggcgggagcactcctgctgaggccggcttctgg gcggctgtcgaggagggcgacgcgggttcgctggcggagctgctcggggtggatgcgggc gagatcgatctggccgcgctgaccgagtggcgtcgtcgggagcgggccgacgcgacggtg gccgactggcggtaccgggtcacgtggatgccggtcgcggagtccgcgggggtgttgtcg ggacggtggctggtcgttggcgacggcgcggaggcggaagccgtcggggcggtgctggcc gagcgtggtgcggaggttgtggccgttgccgggccggagcaggttgccgccgcgagtgat atcgctgatgtgacgggtgtggtgtcggcgttggcgctgtcggatgcggagcatccggag ttcccggtggtgccggccgggctgatggcgacggtggagctgctgcgggcactgggtggc gccggcgtgtcggcaccgctgtgggtgctgacgcggggtgcggtcggtaccggggcgggc gatccggtcgtcaacctgactcaggcggaggtgtggggtcttggcgtaacggctggtctg gagctggccgggcgctggggtgggctgatcgatctgccggcggtgctggatgcgcgggcg ggtgggcggctggtgtcgatgctcgccgatggtggcgaggaccaggtcgcgatccgtgca ggtggcgtcgtcgggcggcggctggagcatgccccgaggccggttgtacggcaggcgtgg gctccgcgcggctcggtgctggtgaccggtgggaccagtggggttggtgcgatcacggcc ggctgggtggtcgagcgcggtgctgcgcgagtggtgctgaccagtcggtcggggccgcgg gccggtggggtggccggattggccgccgcgctgtcccagtccggggccgcggtggaggtg gtggcgtgtgacgccgccgaccgtgggtccgtcgcgggactggtggagtggatcgacgcc tccggggccgagctgtcttcggtggtgcatgcggccgggctaggtgacggcgggccggtc gaggaggtcgaggcggcggatctggcgcggctgctgtcggccaaggccggtggcgcagcg gtgctggacgagctgacggccgaccgggacctggacgccttcgtcatgttctcctccggc gcggcggcctggggcagcggcgggctgagcgcgtatgcggcggccaacgcctacctcgac gcgctcggcgacagccggcgtgcccggggcctggcggcgacctcgatcgcctggggtgta tgggccggcgtcggcatggcggccagcgagggaggcgagcggctgctggcgtacggaatg gagggcatcgacgcggaacgcgggatgcgcatcctcggccaggcgctggacgcggacgaa agctcgctggctgtcgccggcttcacctgggaacagttcgtaccgacgtacaccctctac cgcccgagcccgttcctgtcgggcgtacccgaggtccgggacgtcctcgccgccgaagcc gaaggggaggccggcggcgaagccgatgcccgtggttcggagctcgcggtgcggctgcgg gggatggccgagggcgagcagcggcagcttctgacggacatggtgcgtggtcatgcggcg gtggtgctggggcatgcgtcggccgaggatgtgctgccgcagcgggcgttcaaggatctc gggttcgattcggtcggtgcggtcgagctgcgtaaccggctggcggcggcggccggtgtg cggctgccctcgacgctgatcttcgactaccccaacgccgccgcgctggcggagtacatc tgcggtgagctcgtgggctcggacgcggcttccgctgagggcgcggtgcgggtggtggcc gcggccggcggtgagccgatcgcgatcgtcgggatgggctgccgttatccgggtgatgtg cgggggcccgagcagctctgggacctggtggcatccgggacggatgcgatctcgccgttc ccgaccgatcgtgggtgggaggccttcgaggaggagttcggcggggaggaggcgctgtcc gggcgctcctacgtgcgagagggcggcttcgtctacgacgcggccaagttcgacgcggac ttcttcgggatcagcccgcgcgaggcgctggcgatggatccgcagcagcggctgctgctg gagacgtcgtgggaggcgatcgagcgggcggggctggctccgtcggcgctgcatgggtcg gcgaccggtgtgttcattggtgccagtggttctggctatgagagcagtctccccgtccat gatcagagtctggacggttaccggctcacgggttcggtttcctcggttgcttcgggccgg atttcgtacgtgctggggctgaccgggcccgcggtgacggtggatacggcgtgttcgtcg tcgctggtggctttgcatcaggcggtgtcggcgctgcgtggtggtgagtgcacgatggcg ctggccggtggtgtggccgtgatgacctcgcctggcgccttcatggagttctccaagcag ggcggcatggcttccagcgggcgctgcaaggcgttctccgacggtgcggacggcatcgtg tggggtgagggcgccgggatggtggtgctggagcggctgtcggatgcgcggcgtaatggg catccggtgctggcggttattcggggtagtgcggttaatcaggatggtgcgtcgaatggt ttgtcggcgccgaacggtccgtcgcagcggcgggtgattcgggcggcgttggcgaatgcg caggtgtcggcggcggacgtggatgtggtggaggcgcacggtacggggacgtcgttgggc gacccgatcgaggccggggcgctgctggcgacttatgggcaggagcggccggacgacgac aggccgctgtggctgggttcggtgaagtcgaacatcgggcacgcgcagcaggcggccggg gtcgccggtgtgatcaagatggtcctggccatgcgtcacggcgtcctgcccaggacgctg cacgccggggatccgtcgtcgcatgtggagtggtcgacggggaacgtacggctgctgcag gaggcgcgggagtggccggctggtgagcagccgcgtcgggcgggtgtttcggcgttcggg atcagcggcaccaatgtgcacctggtcctggaggaggcgccgggcagcgtcgaggagccg gagcctgttcctgagactgtggatgcaccggggttgccggtgtttgagcctgcggttccg gcgtgggtggtgtcggggcggagcgcggtggcacttgctgggcaggcggggcggctgcgt gagcatgtggtgggtcggcctgcggtgccggtgggggatgttgcttggtcgttggctacg tctcggtcggtgttcgagcatcgtggggtggtgctcggggctgagcgcgaggagctggtg gccggactggcggcggtggccaccgaccagccggctgccggtgtggtgacgggcgaggtg tcgccggttggcgtggggcggacggtgttcgtcttcccggggcaggggtcgcagtgggtc gggatggggcgggaactggccgagtcctcgcctgtcttcgcggcaaggctggccgagtgt gcggcggcgttggaaccgttcgtggactgggagttggatgacgtcctggccggtcggcat gggtttgaggctgcggatgtggtgcagcctgcgctgtgggcggtgatggtttccctggcc gccgtgtggcaggccgccggtgttgagcctgaggcagtcgtcggccactcccagggggag attgcggctgctgcggtggccgggattctctcgctggaggatgcggcgaaggtggtggcg ctgcgcagccgtgccttgaccgcgctggccggtcgcggcgggatgctgtcgatcgctgag cccgtcgcagcggtacgggagcggatcgccgccttcggtgatcggctgtcgatcgccgcc gtcaacggcccgtcggcgaccgtggtctcgggcgaaccggacgcgctgcgcgaactggcc gactcctgtggggagtcggtgcgtacgcggctgattccggtggattacgcctcgcacagc ccgcaggttgatgagctgcgcgacgacatcctggcggccctcgacggcatcacgccgggt gagacgcgggttccgatggtctcggcgatgagtggagagatgctcgccgggccggagatg gatgccggctactggtacgcctcgctacgcgagccggtcgaattcgaccaggcgatccgc gtgctgggtgaggccgggcacggggtcttcgtagaggcctctccgcatccggtgctcatc caggccatcagcgacagcctggacgagaaggcgccggtggcggtgggcagtctccggcgc gacgacggtggtacggaacgcctgctgacctccttcgcggaggcgttcgtacggggtgtg gccgtcgactggaccgcggtgctgggtgccggcgacacggtggagctgccgacgtatgcc ttccaggagcggcacttctggccggagacgcgggcggctgaggtgcttggggtctcggag ggggatgccgagttctgggccgcgatcgagggcggtgacctggaggagcttgccgcgacg ctgaacgtcgatggcgacaggctcgccgagatggtgccggtgttggccgagtaccggcgg cgcagtcaggtcgacgcggccgtcgccgattggcgttatcgcgtcaggtggactccggtt gccgaggccgggtcggtgctgtcggggcggtggctggtggtcggcgatggcgccgatgcg gaggctgtgtcggcggtgctggcggagcgtggcgcggaggtcgtggtcgttgcggggccg gagcaggttgcggcgagcgatgtcgctgatgtggcgggtgtggtgtcggcgttggcgctg tcggatgcgacgcatccggagtatccggtggtgcctgccgggctgatggcgacggtggag ctgatacgggcgctgggtgctgccggggtgtcggctccgctgtgggtgctgacgcggggc gcggttggcacgggcgcaagcgacccggtggtcagtcccgtacaggcacaggtgtggggt cttggcgtaaccgctggtctggagctggtcgggcgctggggcgggctgatcgatctgccc gcggtgtgggatgcgcgggcgggtggccggctggtgtcggtgcttgccggtggtggcgag gatcaggtcgcgatccgtaccggtggcgtcctcgggcggcggctggagcacgccccccgg gcggccgtcggggaaacatgggccccgcggggctcggtgctcgtcaccggtggcaccagc ggagtcggcgcgatcaccgctggctgggtggccgagcgtggcgctcccagggtggtgctg accagtcggtcggggccggctgccgccggggtggccgggctggcggccgctatggctcag accggggctgcggtggaggtggccgcgtgtgacatcgccgaccgtggatccgtcacggga ctgctggagtggatcgacgcctccggggctgagctctcttcggtgctgcacgccgccggg gtcgccggcggagggccggtggaggaggtcgaggcggcggaactggcgcggctgctggcg gccaaggccggtggcgccgcactgctggacgagctgacggccgaccgggagctggatgcg tttgtgttgttctcatccggtgcggggacgtggggcagtggtgggttgagcgcgtatgcg gcggccaacgcgtacctcgacgggctctgtgacagccggcgcggccgggggctggcggcg acctcggtcgcgtggggtctgtgggccggcgtcggcatggtcgccggtggtgacggtgcg cggctgtcggactttggcatggcgggcattgatgcggagcgtgggatgcgcgctctgggg caggtgctggacgcgggtgagggtgcgctggcgttcgccggcttcgactgggagcagttc gtaccgacgtacaccctctaccgccccagcccgctgctgtccggcctgcctgaggtgaag gatgtcctggaggccacggaagaggtcgccgcggcggccgacgggtccgaactgggcgtc cggctgcggggcatgtcggtcggtgaccagcggcaggagctgacgcagctggtgcgtggc catgcggcggcggtgttggggcatgagtcggctgaggatgtgctgccgcagcgggcgttc aaggatctgggctttgattcggtcggcgcggtggagctgcgtaaccgcctggtgtcggcg gtcggggtgcggttgccctcgacgctggtcttcgattaccccaatgccgccgcattggcg gagttcattcgcggggaactcgtgggctcggctgaggcagctccgggtgacggcggggtg caggtggtggccgcggccggtggtgagccgatcgcgattgtcgggatgggctgccgcctt ccgggtgatgtgcgagggcccgagcagttctgggagctgctgacggccggcacggatgcg gtttccggcttcccgaccgaccgtgggtgggaggcgtttgaggaggagtacggcagcgag gcggtgcggacgggccgttcctatgtgcgggaaggcggcttcctttacgacgccgcggac tttgacgcgggcttcttcgggatcaatccgcgtgaggcgctggcgatggatccgcagcag cggctgctgctggagacgtcgtgggaggcgatcgagcgggcgggactggcgccgtcgtcg ctgcacggctcggccaccggcgtcttcatcggggccacctactcgggttacgagggcaac cttccgactcacgacgaaagcctggacggctaccggctgaccggcatgatctcctcggtc gcctcgggtcggatctcgtacgcgctggggctgaccgggcccgcggtgacggtggacacg gcgtgctcgtcgtcgctggtggctttgcatcaggcggttacggcgctgcgtggtggtgag tgcacgatggcgctggccggtggcgtggccgtgatgacttcgccgggcgccttcatggag ttctccgagcagggtggcatggcttccagcgggcggtgcaaggccttctcggatgaggcc gatggcatcggttggggtgaaggtgccggtgtgctgctgctggagcggctgtcggatgcg cggcgcaatgggcatcaggtgctggccgtggtccggggcagcgctgccaatcaggatggt gcgtcgaatggtctgtcggcgccgaatgggccttcgcagcggcgggtgattcgggcggcc ctggcgaacgcgcaggtgtcggcggcggatgtcgatgtggtggagacgcacggtacgggg acgtcgctgggcgatccgatcgaggctggtgcattgctcgccacgtacggccaggagcgg ccgggtgcggagcggccgttgtggatcggttcggtgaagtccaacatcgggcatctgcag tgtgctgccggtgtggccggtgtgatcaagatggtgctgtcgctgcagcatgggcagttg ccgcggacgctgtatgcggagacgccgtcgacgcaggtggattgggcggcaggggacgta cggctgcttcaggaggcgcgtgagtggcctgctggtgagcagcccaggcgggcgggtgtc tccgcattcgggatcagcggcacgaatgtgcatgtgatcttggaggagacgccggctgag gccggggagccggagcctgcgggtgagggtgagccggagctgccggtgtttgcgtcggcg gttccggcgtgggtggtgtcggggcacagcgcggcggcgcttgctgggcaggcggggcgg ctgcgggagcatgtcgtgggtcggcctgggatcccggtggcggatgtggcgtggtcgttg gctacgtcgcggtcggtcttcgagcaccgtgcggtggtgctcggtggtgagcgggagaaa ctgctggcggggctggcgtccgtagccatgcagcagcctgctgccggtgtggtgagcggc gaggtcgcgcctggtgggatcgggcggacggtgttcgtcttccccggtcagggctcgcag tgggtggggatgggccgggaactggccgagtcctcgccgctgtttgcggctcggctggcg gagtgcgcccaggcgctggctccgtacgtggagtgggagctggatgacgtcctggctggt cggcatggatttgaggccgcggatgtggtgcagcccgccctgtgggcggtgatggtctcc ctggctgccgtgtggcaggccgctggagtcgagcccgacgcggtcgtcggtcactcgcaa ggcgagatcgcggcagccgcggttgccgggatcctgtcgctggacgacgcggcgagggtg gtcgcgctgcgcagccgtgccctgaccgtgctggcagggcgtggcgggatgctgtcggtc gcagagccggtcgcggcggtgcgggagcggatcgcttcgtacggcgagcggctgtcgatc gccgcagtcaacggcccgtcggcgaccgtggtctcgggcgagccggaggcgctgcgcgaa ctggtcgactcctgtggggagtcggtgcgtacgcggctgatcccggtcgactacgcctcc cacagcccgcaggtcgacgacctccgcgacgacatcctcgccgccctcgccggcatcacg cccagcgagccccgtatcccgatgatctccgcgatgacgggcgaaatgatctccggtccg gagatggacgccggctactggtacgcctcgctgcgcgagccggtcgagttcgaccgagcc atccgcgccctgggcgaggccggccacggcgtgttcgtggaaacgtccccgcatccggtg ctgatccaggccatcgccgacagcctgcaagaccgcgacccgatcaccgtgggcagcctg cggcgcgacgacggcggtacggaacgcctgctggcctccctctccgaggcgttcgtaggc ggcgtgcccgtcgactggacggcggtgctgggtggcggggacaccatcgacctgccgacg tatgccttccagcgacgccggttctggcccgaggtggctgctccgcagcgcaagtccgtg gatgactggcgttaccggatcacctggcagcagtccgacctcggtggcggcgttcccgcg ctgtccgggacctggctgctggtcggcgacgatccggacgcaccggcgatcgcggaggcg ctgaccggtcacggcgccgaggtcgtcaccgtccccgctcccgcggaactggacccgtcc gcgctggcggaagccgcaggtgtggtgtcgctgctggccctggacgagaccccggacgcg tcctatccgtgggtgccgagcggcaccgcgacgacgctggacctcgtacacgcgctgcat cagtccggaacggccgcgcccgtctgggtgttgacgcggggtgccgtacagacgggtgcg ggcgaggtgacgaccagcccgtcccagaccgccgtgtggggcctgggccgggccgtcggc ctcgagcaccccgggctgtggggcgggctgatcgacctgccgacggcattcgatgggcgg gccgggatgggcctggtgtccgtgctggcgcagccgagtgaggatcaggtcgcgctgcgg gccgaaggtgtcttcctgcggcgtctggtacgggcggaggcgcggcgcgcggaggccggg cggtggacgccgcggggcacggtgctgctgaccggtggcaccggctcgatcggggcgagt gtcggcggctggctcgccgaacacgacacctcgcgcgtggtgctgacctcgcgttccggg ccgtcggctcccggcgtgcccgccctcgccgcgtcggtcgcggccggcggtaccgctgtg gaggtggtcagctgcgacctgggggtgcccgagcaggtctccgggatggtgtcgtggatc gagacatccgggccggggctgtcgacggtgctgcactcggcgaaccagccctatctggcc cgcgtcgaggacacggaacgggacgggctggccgccgcactcggcgccaaggcggccggt gcggtgcacctggaccaggccaccgccgggctggatgtggacgagttcgtgctcttctcg tcgatctcggccacgtggggcagcaacgaccacggcgcctacgccgccagcaattccttc ctcgacgggctcgccgaacagcgccgttcccgtggcctgccggcgacgtcgatcgcctgg ggagtgtgggacacccgcgactgggacgcggtggacgcgtcgatgaagcaggggccgggc gcggtcacgcccagccgcctgcgccgccagggcatgaacttcctggacaccgatcgcgcg ctgaccgcgctgggcgaggtgctggcggacgacgagaccttcatcgcggtcgccgacgtc gagtgggagcggttcgccccggtgttccgcgctgttcgtccgcggccgctgctggacacg attcccgaggcgcaggaggagctcggtcccatcgggtcggtggagaccgcggtggccggc cgtggcgagtacgcgtcccgcctcgccgggatggcggcgggagagcgtcgtcgtacggtc gttgacctggtgcgttcccatgccaccgcggtgctggggcacgcctcggtggacgagata cctgccgagcgggcgttccgcgatgtcgggttcgactcgctgacggcggtcgagctccgt aaccggctcaacgccgcggccggggtccggctgccgtcgaccgtggtcttcgatcacccc aaccccgcggcgctggctgaggagatcctcaccggactgttcggtgtggagtccggggcg gagcgtggcgtgacggtggctgctgcagcgccgtcggagccgatcgcgattgtggggatg ggctgccgttaccccggtggcgtgcgtagcccggaggagctgtgggcgctgctggcttcg ggtggggatgccatttcggggttcccggtcgatcgggggtgggatgccgaggcgctgttc gatccggatccggatgctgagggctcgacgtatgtgatggagggcggcttcatcaccgga gccgggcattttgatgcggacttcttcgggatcagtccgcgggaggcactggcgatggat ccgcagcagcggctgctgctggagacgtcgtgggaagccattgagcgggccggcattgat ccgggttcgttgaagggttcgggcaccggtgtgttcgtgggtggtaccacgtcgggatac gtcggttcggctatggacactgccggggcggaaacgcatctgattaccgggaatgcgctg agtgtgctgtccgggcggatttcgtattcgctggggctggttggcccggcggtgtcggtg gatacggcgtgttcgtcgtcgttggttgctttgcatcaggcggctcaggcgttgcggtcg ggtgagtgcacgatggcactggccggcggtgtgatggtaatggccgatccgagtgagttt gtgggcttctcgcggctgcgggcgttgtcttcggatgggcggtgccgggccttcggtgac ggtgccgatgggatgggcattgctgaaggtgccgggatggtgatgctggagcggctgtcg gatgcgcggcgtaatggacatccggtgctggcggtcattcgcggcagtgccgttaatcag gatggtgcgtcgaatggtttgtccgcgccgaatggtccgtcgcagcggcgggtgattcgg gcggcgctggcgaatgcgcaggtgtcggcggcggatgtggatgtggtcgaggcgcacggt acgggtactgagttgggtgacccgatcgaggccggggcgctgctggcgacgtatgggcag gagcggccggatgcggatcggccgttgtggatcgggtcgatcaagtccaatatcgggcac gcgcagcaggcggccggggtcgcgggactcatcaagatggtgatgtcgctgcagcacggg cagctgccgcagacgctgtatgcggacacgccgtcgtcgcatgtggagtggtcgacgggg aacgtacgcctgcttcaggaggcgcgggagtgggcggctggtgagcgtccgcgtcgggct ggtgtgtccgcgttcgggatcagtggcaccaacgcgcacctgatcctggaggaggcgccg ggcaccgtcgaggaggcggattccgagctggagcctgcgggggaggggcagctggggttg ccggtgtttgcgccttcgcttccggcgtgggtggtgtcggggcgtagtgcggtggcgctg gctgagcaggctgggcggctccgggagcatgtcgtgggccgaccggggttgccggtcggg gatgttgcttggtcgttggccacgtcgcggtcggttttcgagcaccgtgcggtggtgctc gggggtgagcgggaggagctgctggcggggctggcggcggtggccaccgaccagcctgcg gctggtgtggtgagcggcgagacggcgtcgggtacagccggtgggacggtgttcgtcttc ccgggtcagggcagtcagtgggtcgggatgggccgggagctggccgcgtcttcgcctgtc ttcgcggcgcggctggccgagtgtgcccgggctctcgcgccctacgtggagtgggagctg gatgatgtcctggctggtcggcacggctttgaggctgcggatgtggtgcagccggccctt tgggcggtgatggtctccctcgccgccgtgtggcaggccgctggcgtccagcccgacgcg gtagtcggccactcgcagggcgagatcgccgctgcggcggtggcagggatcctctcgctg gacgacgcggcgaaggtggtggcgctgcgcagccggacgctggccgcgctggccggccgg ggcgggatgctgtcgatcgccgagccggtcgcagccgtacgggagcggatcgccgccttt ggtgatcggctgtcgatcgctgccgtgaacggcccgtcggcgaccgtggtctcgggcgag ccggacgcgctgcgcgaactggccgactcctgcggggagtcggtgcgcacgaggctgatc ccggtggactacgcctcccacagcccgcaggtcgacgaactctgcgaggacatcctggcg gccctcgatggcatcacgcccagcgagacccgtatcccgatgatctccgcaatgacgggc gacatgatctccggaccggacatggacgccgggtactggtacgcctcgctgcgcgagccg gtcgagttcgaccgggccatccgtaccctcggtgagtcagggcacggcgtgttcgtggag gcgtctccgcatccggtgctgatccaggccatcagcgacagcctgtacgagaaggcgccg gtggcggtgggcagtcttaggcgcgatgacggtggtacggagcggctgctggcctccctt tccgaggcgttcgtacgtggtgtggccgtcgactggacggcggtgctgggtggcggcgag accgttgacctgccgacctatgccttccaggagcggcactactggccggaggcgcggccg gttgaggtgccggaggtctcggcgggggatgccgagttctgggctgcggttgagggcggc gatcttgaggagcttgctgccacgttgaatgtcgatggggccgggatcgccgagatcgtg ccggtgttggctgagtaccggcggcgcagtcaggccgatgcgacggtcgcggactggcgt taccgcgttacctgggcgccagtagtcgagtccgcggccgtgctgtcggggcggtggttg gtcgtcggtgatggcgccgatgcggaggctgtgtcggcggtgctggcggagcgtggcgcc gaggtcgtggccgtagccgacctgggccggcttgctgcgttcgacgccgctgatgtggcc ggtgtggtctcggctttggcggtgtcggatgcggcgcatcctgagcatgaggtggtgcct gccgggctggtcgcgaccgtggagctggtacgggcgctgggtgccgctggagtgtcggct ccgctgtgggtgctgacccggggcgcggtcggtaccggcgcaagcgacccggtcatcagt cccgtacaggcgcagatctggggtctgggcgtggtggccggtctggagctggctgggcgc tggggcgggctgatcgatctccccgaggtgtgggatgcgcgggccggtggccggctggtg tcggtgcttgccgatggcggcgaggatcaggtcgcgatccgtgcaggtggagtcctcggg cggcggctggagcacgccccccggccggccataggtgaagcatgggctccgcggggctcg gtgctggtgaccggtggcacgagtggggtgggtgcgatcaccgctggttgggtggccgag cgtggtgctgctcgggcggtgctcaccagccggtcaggcgcggctgccgctggggtggcc gggctggcggcctcgatcgccacggccgggacggccgtggaggtcgtcgcgtgcgacatc gccgaacgtggatccgtcgcgggattgctggagtggatcgatgccgatgggcccgtgttg tcgtcggtgatgcatgcggcgggtgtcggggatcggcggccggtggcggagctcgaggcg gctgagctggcgtatgtgctggcggctaaggccggtggtgccgctctgctggacgagttg accgctgggcgggagctggatgcgtttgtgttgttctcgtccggtgcggggacgtggggc agtggtgggctgagcggttatgccgcggccaacgcctacctcgacgcgctgtgcgacagt cggcgtgcccggggcctggtggcgacctcgatcgcctggggtctgtgggccggcgtcggc atggccgccgtcggaggcagcggtgagcggctgctggacttcggcatggcgggcatcgac gcggagcgcgggatgcgcgccttggggcaggcgctggatgcgggcgagggcgtgctcgcg gttgccggcttcgactggcccaagttcgtgccgacttacacccttcaccgggccagcccg ttcctgtcggggctgcctgaggtccgggccgtgctcgccgctgaagccgacccgaccgat ggggctgccggtgacccgagcgcttcggagctggcgatccgactgcgcggcatgggcgag ggtgagcagcggcaggagctgacgcagctggtgcgtggtcatgcggccgcggtgttgggg catgcgtcggctgaggatgtgttgccgcagcgggcgttcaaggacctcggatttgattcg gtcggtgcggtcgagctgcggaatcggctggcgaacgcggccggggtgcggctgccctcc acgctcgtcttcgactaccccaacgcagtgacgttggcggagttcatccggggtgagctg gtgggctcggactcggcttccgctgagggcgcggtgcgtgtggtggccgcggctgggggt gagccgatcgcgatcgtcggcatgggctgccgataccccggcgatgtccgtgggcccgag cagttctgggaattgctgaccaacggcacggacgctatctccggcttcccgaccgaccgt ggttgggagtcggtcgaggaggagtttgacgggaaggcggcccggtccggccgctcctat gtgcgcgaaggcggcttcgtttatgacgtagccgattttgatccgggcttcttcgggatc aatccgcgtgaggcactggcgatggatccgcagcagcggctgctgctggagacgtcctgg gaggcgatcgagcgggcgggactggcgccgtcgtcgctgcacggctcggccaccggcgta ttcatcggcgccaccggttctggctacgacaacgctttgcctcatgacgatcagagtctg gacggctaccggcttatcggaaccgtttccgcagtcgcctccggccggatttcgtacgtg ctggggctgaccggtcctgcggtgacggtggatacggcgtgttcgtcttcgctggtggcg ctgcatcaggcggtgtcggcgctgcgtggtggtgagtgcacgatggcgctggccggtggc gtggccgtgatgacttcgccgggtgcgttcatggagttctccgagcagggcgggatggcc tccagcgggcggtccaaggcgttctcggatgaggccgatggcatcggctggggtgaaggt gccggtgtgctgctgctggagcggctgtcggatgcggaacgtaacgggcaccaggtcctg gccgtcatccgcggcagcgccgtgaaccaggacggcgcctccaacggtctgtccgcgccg aatggcccgtcgcagcggcgggttattcgagcagcactggcgaacgcgcaggtgtcggcg gcggatgtcgatgtggtggagacgcacgggacgggtacatcgctcggtgatccgatcgag gccggggcgctgctggcgacctatggccaggagcggccgggcgacgacaggccgttgtgg atcggttcggtgaagtcgaacatcgggcatctgcagacggcggccggtgtcgccggtgtg atcaagatggtgctgtcgctgcagcacagccaattgccgcgaaccctgcatgcggagacg ccgtccacgcagatcgactggacggccgggaacgtccaactgctacaggagcagcgcgag tggctgccgaatggtcggccgcgtcgggcgggtgtctccgcattcggggtcagcggcacc aacgcgcacgtgatcctggaggaggcgccggtcgccgtcgaggagcctgagcctgtttcc gagaccgtggatgccccggtgctgccggtgctagcgcgtgcggttccggcgtgggtcgta tcaggtcgaagtgcggtggcgttggcgggtcaggcggggcggctgcgcgagcatgtggtg ggtcggcctgggatcccggtgggggacgttgcgtggtcgttggccacgtcgcggtcgatt ttcgagcaccgtgcggtggtgctcggggctgagcgggaggagctgctggccgggctggcg gcggtggccaccgaccagccggcggctggtgtggtgaccggcgaggtgtcgccggtcggc gtggggcggacggtctttgtcttcccgggccagggcagccagtgggtcgggatgggccgt gaattggccgagtcctcgcccgtcttcgcggcgaagctcgccgagtgcgcggcggcgctg gctccctatgtcgactgggagttggatgacgttctggccgggcagcatgggttcgaggct gcggatgtggtgcagcctgcgctctgggcggtgatggtctctttggccgccgtctggcag gccgccggcgtccagcccgacgccgtggtggggcattcccagggcgagatcgcggcggct gcggtggccgggatcctgtcgctggacgacgcggccaaggtggtcgcactgcgcagccgg acgctggccgcgctggccgggcgcggcgggatgctgtccatcgcagaacccgtcgcagcg gtgcgagagcggatcgcctccttcggcgagcggctgtcgatcgccgccgtcaacggcccg tcggcgaccgtggtctcgggcgagccggacgcgctgcgcgagctgcaggacgggtgcggg gagtcggtgcggacacgcctgattccggtggattacgcctcgcacagcccgcaggtcgac caactccgcgacgacatcctcgccgcgctggacgggatcgctcccggcgaggcgcgcatc ccgatggtctcggccatgagcggtgaatggctgacggggccggagatggatgccggctac tggtatgcctcgctgcgcgagccggtcgagttcgaccaggcaatccgcgtcctgggtgag gccggccatggcgtgttcgtagaggcctctccgcacccggtgctgatccaggccatcgcc gacagcctcgacgaggcgtcgccgatcaccgtaggcagcctgcggcgcgacgacggtggt acggagcggctgctgacctccctctccgaggcgttcgtaggcggcgtgcccgtcgactgg acggcggtgctgggtggcggcgcgacggtggagctgccgacgtatgccttccagcggcgc cgcttctggcccgaggtacccgctgcccagcggaagtccatggatgactggcgttatcag atcacctggcagcagtctgacctcggcggtctctctgcgttgtccgggacctggctgctg gtcggggacgatcgggaggcactcgcgatcgcggaggcgttggcagggcacggcgccgac gtggtcaccgtcgccggtcccgacgagctgaccccatccgcgctggcagatgccgcgggt gtggtgtcgctgctggccttggacgagaccccggatgcggagtttccgtggatctcgcgg ggcattgcggcgacggtggagctggtccaggcggtgcagcaggccggggccgaggttgcg gtgtggacgctgacccgcggcgcggtgcagaccggcgcgggcgaggtgacgaccagcccg tctcagaccgcggtctggggcctgggccgcgcggtcggccttgagcgtcccgagctgtgg ggcggcctcatcgacctgcccaccgagttcaccgaccgaacaggcacccacctcgcatcc gtcctggcgcaaaccagcgaggatcaagtagcgctgcggaccgaaggcgtcttcctgcgc cggctggtacgggtcgaggcgcgccgtgcgcaggccggacgctggtcgccgcggggcacg gtcctgctgaccggtggcaccggctcgatcggcgtcagcatcggcggctggctcgccgat cacgacacctcgcgggtggtgctgacctcccgttccgggccgtccgctcccggcgtaccc gccctcgccgcctcgatcgcggcaggcggcaccgatgtcgaggtgctcagctgcgacctg cagaccctggagcaggtctccggcatggtgtcctggatcgaggcgtccggacccggcctc tcgacggtgctgcactcggcgaatcagccctacctggcctgggtggagaacaccgagcgg gaaggcctggccgccgcgctcggcgccaaggcagtcggcgcggtgcatctggaccaggcc accgccgggctggatgtggacgagttcgtgctgttctcgtcgatctcggcgacctggggc agtaacgaccacggcgcctacgcggcaggcaactccttcctggatggcttcgccgaggac cgccgctcccgtggtctcccggcgacgtccatcgcctggggcgtgtgggatacccgcgac tgggatgccgtcgatgccgcgatgacgcagggggcgggagcggtaacccccagccgcttg cgtcgccagggcatgaacttcctcgacaccgaccgcgccctgaccgccctcggcgaaatc ctcaccgaagacgagaccttcatcgccgtcgccgacgtcgaatggcagaagttcgccccc gtcttccggatggcccgcccccgccccctcctggacaccatccccgaggcccaggacgac cccgcacccgcggcgtcaacgggcgccggagacgacggctacagcgaatacgccgcccgc ctcgccgccctctcggaggccgagcgccgccgtacggtcatcgagctggtccgctcccac gccaccgccgtcctcggccacgactccaccgacgagatcgacgcggcccgcgccttccgc gacgtcgggttcgactcgctcaccgcggtcgagctccgtaaccggctcaacgccgccgcc ggagtccggctgccgtccaccgtggtcttcgaccaccccaaccccacggccctggccgag gagatcctcacccagctgttcgagaacgaactggtgggccacacggccgtgctggacgag ttcgaacgcctggcagccgggctcacgccctcggacgaagcggcccgtaccgagatcgtc gcccggctggaagcgctgacccagcggttccgcgccctccggtccgagcaggggacggcg ggaggcgtcgtggacgaagcggagcagcaacgcgcgctcgaggaggcgaccgcggacgag ctgttcgccctcctggaggacgaactcgacgatcccgacctcgactga

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