Saimiri boliviensis boliviensis (Bolivian squirrel monkey): 101028157
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Entry
101028157 CDS
T04350
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
sbq
Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Pathway
sbq04140
Autophagy - animal
sbq04141
Protein processing in endoplasmic reticulum
sbq04210
Apoptosis
sbq04932
Non-alcoholic fatty liver disease
sbq05010
Alzheimer disease
sbq05012
Parkinson disease
sbq05014
Amyotrophic lateral sclerosis
sbq05016
Huntington disease
sbq05017
Spinocerebellar ataxia
sbq05022
Pathways of neurodegeneration - multiple diseases
sbq05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
sbq00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
101028157 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101028157 (ERN1)
09143 Cell growth and death
04210 Apoptosis
101028157 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
101028157 (ERN1)
05012 Parkinson disease
101028157 (ERN1)
05014 Amyotrophic lateral sclerosis
101028157 (ERN1)
05016 Huntington disease
101028157 (ERN1)
05017 Spinocerebellar ataxia
101028157 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
101028157 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101028157 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101028157 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
sbq01001
]
101028157 (ERN1)
Enzymes [BR:
sbq01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101028157 (ERN1)
Protein kinases [BR:
sbq01001
]
Serine/threonine kinases: Other
IRE family
101028157 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Beta-prop_ACSF4
PQQ_2
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
101028157
NCBI-ProteinID:
XP_010328634
LinkDB
All DBs
Position
Unknown
AA seq
1039 aa
AA seq
DB search
MRKVLAAVSLPLLVGLYRGKGIWDPGVFVLPPQAALERACGSFPLKDLTRHPGSYQEEPG
LLESGSHAQITPILLHLRLHTSILGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTL
KEDPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGIL
YMGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWN
ATYFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREG
LRKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYAS
PSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKNKLNYLR
NYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENTPT
TVSRDVEEKPAHAPARPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSMHQQQQLQH
QQFQKELEKIQLLQQQQLPFHPPGDAAQDGELLDTSGPCSESSGTSSPSTSPRASNHSLC
SGSSASKAGSSPSLEQDDGDEETSMVMVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAV
KRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDF
AHLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKL
AVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKS
LQRQANILLGACSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQ
LQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVR
DLLRAMRNKKHHYRELPLEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQ
PYYFHEPLEPQPPVTPDAL
NT seq
3120 nt
NT seq
+upstream
nt +downstream
nt
atgcgaaaagttctggcagctgtttcactccctctgctggtgggtctctaccgtggaaaa
ggaatatgggaccctggagtatttgtcctgccacctcaggctgccctggagagagcgtgt
gggagcttcccgttgaaggatttaactaggcatcctggctcttaccaagaggagccaggc
cttctggaatcaggctcccatgcacaaataaccccaatccttttacatttaaggctccat
acttctattttgggaagtaccagcacagtgacgcttcctgaaaccttgttgtttgtgtcc
acgctggatggaagtttgcatgctgtcagcaagagaacaggctcaatcaaatggacttta
aaagaagatccagtcctgcaggtcccaacacatgtggaagagcctgcctttctcccagat
cctaatgatggcagcctgtatacacttggaggcaagaataacgaaggcctgacaaaactt
ccttttaccatcccagaattggtgcaggcatccccgtgccgaagttcagatggaatcctc
tacatgggtaaaaagcaggacatctggtatgttattgatctcctgaccggggagaagcag
cagactttgtcatcggcctttgcagatagtctttgcccatcaacctctcttctgtatctt
gggcgaacagaatacaccatcaccatgtatgacaccaaaacccgagagctccgatggaat
gccacctactttgactacgcagcctcactgcccgaggacgacgtggactataagatgtcc
cactttgtgtccaatggtgatgggctggtggtgaccgtggacagtgaatctggggacgtc
ctgtggatccaaaactacgcctcccctgtggtggccttctatgtctggcagcgggagggt
ctgaggaaggtgatgcacatcaatgtcgctgtggagaccctgcgctatctgaccttcatg
tctggggaggtggggcgcatcaccaagtggaagtacccgttccccaaggaaacagaggcc
aagagcaagctgacgcccactctgtatgttgggaaatattctaccagcctctatgcctcc
ccttcaatggtgcacgagggggttgctgtcgtgccccgcggcagcacacttcctttgctg
gaaggcccccagactgatggcgtcaccattggggacaagggggagtgtgtgatcacgccc
agcacggacctcaagtttgaccccggactcaaaggcaagaacaagctcaactacttgagg
aattactggcttctgataggacaccatgaaaccccactgtctgcatctaccaagatgctg
gagagatttcccaacaatctgcccaaacatcgggaaaatgtgattcctgctgattcggag
aaaaagagctttgaggaagttattaacctggttgaccagacttcagaaaacacacctacc
actgtgtctcgggatgtggaggagaagcctgcccacgcccctgcccggcccgaggccccc
gtggattccatgctcaaggacatggccaccatcatcctgagcaccttcctgctgatcggc
tgggtggccttcatcatcacctacccgctgagcatgcatcagcagcagcagctccagcat
cagcagttccagaaggaactggagaagatccagctcctgcagcagcagcagctgcccttc
cacccacctggagatgcggctcaggacggcgagctcctggacacgtctggcccatgctca
gagagctcaggcactagcagccccagcacatcccccagggcctccaaccactcgctctgc
tccggcagctctgcctccaaggctggcagcagcccctccctggaacaggatgacggagat
gaggaaaccagcatggtgatggttgggaaaatttccttctgtcccaaggacgtcctgggc
catggagctgagggcacaattgtgtaccggggcatgtttgacaaccgcgacgtggctgta
aagaggatccttcccgagtgttttagcttcgcagaccgtgaagtccagctgttgcgagaa
tcggatgagcacccgaacgtgatccgctacttctgcacggagaaggaccggcaattccag
tacattgccatcgagctgtgtgcagccaccctgcaagagtatgtggagcagaaggacttt
gcgcatctcggcctggagcccatcaccttgctgcagcagaccacctcgggcctggcccac
ctccactccctcaacattgttcacagagacctaaagccccacaacattctcatatccatg
cccaatgcacacggcaagatcaaggccatgatctccgactttggcctctgcaagaagctg
gcagtgggcaggcacagcttcagccgccgatctggggtgcctggcacagaaggctggatt
gctccagagatgctgagcgaagactgtaaggagaaccctacctacacggtggacatcttt
tctgcaggctgcgtcttttactacgtgatctctgagggcagccacccatttggcaagtcc
ctacagcggcaggccaacatcctcctaggtgcctgcagccttgactgcttgcacccagag
aagcacgaagacgtcattgcacgtgaattgatagagaagatgattgcaatggatcctcag
aaacgcccctcagcgaagcacgtgctcaaacatccgttcttctggagcctagagaagcaa
ctccagttctttcaggacgtgagtgacagaatagaaaaggaatccctggatggcccgatc
gtgaagcagttggagagaggcgggagagccgtggtgaagatggattggcgggagaacatc
accgtcccgctccagacagacctgcgtaaattcaggacctataaaggtggttctgtcaga
gatctcctccgagccatgaggaataagaagcaccactacagggagctgcctctggaggtg
cgggagacgctgggctccctccccgacgacttcgtgtgctacttcacatctcgcttcccc
cacctcctcgcacacacctaccgggccatggagctgtgcagccatgagagactcttccag
ccctactacttccatgagcccctggagccccagcccccagtgactccagatgccctctga
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integrated database retrieval system
