Saimiri boliviensis boliviensis (Bolivian squirrel monkey): 101032514
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Entry
101032514 CDS
T04350
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
sbq
Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Pathway
sbq00230
Purine metabolism
sbq00670
One carbon pool by folate
sbq01100
Metabolic pathways
sbq01523
Antifolate resistance
Module
sbq_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
sbq00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101032514 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101032514 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101032514 (GART)
Enzymes [BR:
sbq01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
101032514 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
101032514 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
101032514 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_2
ATP-grasp_4
Dala_Dala_lig_C
ATP-grasp_3
RimK
Sacchrp_dh_NADP
SNF5
LUD_dom
Vitellogenin_N
GAE_BBS1
ATP-grasp_5
Motif
Other DBs
NCBI-GeneID:
101032514
NCBI-ProteinID:
XP_003927696
UniProt:
A0A2K6TT98
LinkDB
All DBs
Position
Unknown
AA seq
1059 aa
AA seq
DB search
MGRGGEGRRRARPAPVPVGQLPASGRAGAWWSPGVGFIFLWNFCFADRAMAAQVLVIGSG
GREHTLAWKLAQSNHVQRVLVAPGNAGTACSEKISNTAVSISDHTALAQFCKDEKIEFVV
VGPEAPLAAGIVGNLMSAGVRCFGPTAEAAQLESSKKFAKEFMDRHGIPTAQWKAFTKPE
EACSFIMSADFPALVVKASGLAAGKGVIVAKTKEEACKAVQEIMQEKTFGVAGETIVIEE
LLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLKIK
NTILQRTVDGMQQEGTPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQVILPLLKSDLYE
VIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEAQAQGLEVFHAG
TALKNGKVVTQGGRVLAVTAIRENLVSALEEAKKGLAAIKFEGAIYRKDIGFRAIAFLQQ
PRGLTYKGSGVDIVAGNMLVKKIQPLAKATSRSGCNVDLGGFAGLFDLKAAGFKDPLLAS
GTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLNVTEAV
IAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLPHLEIITEGDVV
VGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGELLLTPTRIYSHSLLPVLR
SGHVKAFAHITGGGLLENIPRVLPEKFGVDLDAQTWRIPRVFSWLQQEGHLSEEEMARTF
NCGIGAAIVVSKEQTEQILRDIQQQKEEAWVIGSVVARAEGSPCVKVKNLIESMQINGSV
LKNGFPKNHFSVEQKKARVAVLISGTGSNLQALIDSTREPNSSAQIDVVISNKAAVAGLD
KAERAGIPTRVINHKLYKNRVEFDNAIDLVLEEFSIDIVCLAGFMRILSGPFVRKWNGKM
LNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVTT
LSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
NT seq
3180 nt
NT seq
+upstream
nt +downstream
nt
atggggcggggcggggaggggcggcgccgcgctcgtcccgctccggttccggtgggccaa
cttccggcgagtgggcgagctggagcctggtggtcacccggtgtcggtttcattttcctt
tggaatttctgctttgcagacagagcaatggcagcccaagtacttgtaattggcagtgga
ggaagggaacatacgctggcctggaaacttgcacagtctaatcatgtccaacgcgtattg
gttgctccaggaaatgcgggcactgcctgctctgaaaagatttcaaataccgctgtctcg
atcagtgaccacactgcccttgctcaattctgcaaagatgagaaaattgaatttgtagtt
gttggaccagaagcacctctggctgctgggattgttgggaacctgatgtctgcaggagtg
agatgctttggaccaacagcagaagcagctcagttagagtccagcaaaaagtttgccaaa
gagtttatggacagacatggaatcccaactgcacaatggaaggctttcacaaaacctgaa
gaggcctgcagcttcattatgagtgcagacttccctgctttggttgtgaaggccagtggc
cttgcggctggaaaaggggtgattgttgcaaagaccaaagaagaggcctgcaaagctgta
caggagatcatgcaggagaagacctttggggtagctggagaaacaattgtcattgaagaa
cttcttgacggagaagaggtgtcttgtctatgtttcactgatggcaagactgtggccccc
atgcccccagcacaggaccataagcgattactggagggagatggcggccctaacacaggg
ggaatgggagcatattgtccggcacctcaggtttctaatgatctgctactaaaaattaaa
aatactattcttcagaggacagtagatggcatgcagcaagagggtactccatatacaggt
attctctatgctggaataatgctgaccaaggatggcccaaaagttctagagtttaattgc
cgttttggtgatccagagtgccaagtaatcctcccacttcttaaaagtgatctttatgaa
gtgattcagtctaccttagatggcctgctctgcacatctctgcctgtttggctagaaaac
cacactgccctaactgtcgtcatggcaagtaaaggttatcctggagactacaccaagggt
gtagagataacaggatttcctgaggctcaagctcaaggactagaggtgttccatgcaggc
actgccctcaaaaatggcaaagtagtaactcaggggggtagagttcttgcagtcacagcc
atccgggaaaatctcgtatcagccctcgaggaagccaagaaaggactagctgctataaag
tttgagggagcaatttataggaaagacatcggctttcgtgccatagctttcctccagcag
cccaggggcttaacttacaagggatctggagtagacattgtagctggaaatatgctggtc
aagaaaattcagcctttagcaaaagctacttccagatcaggctgtaacgttgatcttgga
ggttttgctggtctttttgatttaaaagcagctggtttcaaggatccccttctggcctct
ggaacagatggcgttggaactaaactaaagattgcccagctgtgcaataaacatgatacc
attggtcaggatttggtagcaatgtgtgtgaatgatattctggcacaaggagcagagccc
ctcttcttccttgattacttttcctgtggaaaacttgacctcaatgtaactgaagctgtt
attgctggaattgctaaagcctgtggaaaagctggatgtgctctccttggaggtgaaaca
gcagaaatgcctgacatgtatccccctggagagtatgacctagctggatttgccgttggt
gccatggagcgagatcagaaactccctcacctggaaataatcactgagggtgatgttgtt
gttggaatagcttcatctggtcttcacagcaatggatttagccttgtgaggaaaattgtg
gcaaaatcttcccttcagtactcctctccagcacctgatggttgtggtgaccagacttta
ggggagttacttctcacgccaaccagaatctacagccattcactgttacctgtcttacgt
tcaggacatgtcaaagcctttgcccatattactggtggaggattactagagaacatcccc
agagtcctccctgagaaatttggggtagatttagatgctcagacctggaggatccccagg
gtcttctcttggttacagcaggaaggacacctctccgaggaagagatggccagaacattt
aactgtgggattggcgctgccatcgtggtatcaaaggagcagacagagcagattctgagg
gatatccagcagcaaaaggaagaagcctgggtgattggcagcgtagttgcacgagctgaa
ggttccccctgtgtgaaagtcaagaatctgattgaaagcatgcaaataaatgggtcagtg
ttgaagaatggtttcccgaaaaatcatttctctgttgaacaaaaaaaggccagagtggct
gtcttaatatccggaacaggatcgaacctgcaagcactcatagacagtactcgggaacca
aatagctctgcacaaattgatgttgttatctccaacaaagccgcagtggctgggttagat
aaagcagaaagagctggtattcccaccagagtaattaatcataaactgtataaaaatcgt
gtagaatttgacaacgcaattgacctagtccttgaagagttctccatagacatagtctgt
cttgcaggattcatgagaattctttctggcccctttgtcagaaagtggaatggaaaaatg
ctcaatatccacccatccttgctcccttcttttaagggttcaaatgcccatgagcaagcc
ctggaaaccggagtcacagttactgggtgcactgtacactttgtagctgaagatgtagat
gctggacaaattattttgcaagaagctgttcccgtgaagaggggtgacactgtcacaact
ctttctgaaagagtaaagttagcagaacacaaaatattcccagcagccctccagctggtg
gccagtggaactgtgcagcttggagaaaacggcaagatctgttgggttaaagaggaatga
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integrated database retrieval system
