Saimiri boliviensis boliviensis (Bolivian squirrel monkey): 101038132
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Entry
101038132 CDS
T04350
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
sbq
Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Pathway
sbq00310
Lysine degradation
sbq01100
Metabolic pathways
sbq05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
sbq00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
101038132 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
101038132 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
sbq03036
]
101038132 (DOT1L)
Enzymes [BR:
sbq01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
101038132 (DOT1L)
Chromosome and associated proteins [BR:
sbq03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
101038132 (DOT1L)
HMT complexes
Dot1-containing complex
101038132 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
101038132
NCBI-ProteinID:
XP_010337554
LinkDB
All DBs
Position
Unknown
AA seq
1843 aa
AA seq
DB search
MEAPSPAVTYRAFAEAGFPARLELPGWSGSWWACGACPQGLGDKHHDAAHEIIETIRWVC
EEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTG
LLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSG
VGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLS
EEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLS
DIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQ
QRESKSSAATPTKGPEGKAAGPAEAPMDSGAEEEKAGAATVKKPSPSKARKKKLNKKGRK
MAGRKRGRPKKMNTANPERKPKKNQTALDLLHAQTVSQTAASSPQDAYRSPHSPFYQLPP
SVQRHSPNPLLVAPTPPALQKLLESFRIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQL
LGTAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQL
EQDNRTLRSQSLQLLKARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIV
ELEKSQRQQELLQLKSCVPPDDTLALHLRGKGALGRELESDAGRLHLELDCAKFSLPHLS
SMSPELSMNGHAASYELCSALSRPSPKQDTPQYLASPLDQEVVPCTPSHGGRPRVEKLSG
LAVPDYTRLSPAKIVLRRHLSQDHTLPGRPAASELHPRAEHTKENGLPYQSPSVPSSMKL
SPQDPRPPSPGTLQLAGEKSSEKGLRERAYGSGGEPITSLPISIPLSTVQPNKLPVSIPL
ASVVLPSRAERARSTPSPVLQPRDPSSTLEKHIGANAHSAGSKSLALAPAAGFSYAGSVA
ISGTLAGSPASLAPGAEPATLDESSGSGSLFATVGSRSSTPQHPLLLAQPRNSRPASPAH
QLSSSPRLGGAAHGPLPEASKGDLPSDSGFSDPESEAKRRIVFTIATGAGGTKQSPSSKH
SPLTASTRGDCAPSHGQDNRKRGRRKRASTGTPSLTTGVSPKRRALPSVAGLFTQPSGSP
LNLNSMVNNINQPLEITAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLT
SDEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGGVAGRRPAPAGEPVNSSKWKST
FSPISDIGLAKAADSPLQAGPTLSQSSLFAFRPALEETPADAKLAAHPRKGFPSSLSGAD
GLSPSTNPANGCTFGGGLAAELSSHSFSDGASLTHKGPEAAGLSSPLGFPSQRAKEASDA
NPFLSKRQLDGLAGLKGEGGRGKEVGEGGLPLCGPADKTPLPAGKAAKARDRELDLKNGH
NLFISAATVPPGGLLSGPVLAPAASSAGGAGSSAQTHRPFLGPFPPGPQFTLGPMALQAN
LGSVAGSSVLQSLFSSVPAAAGLVHVSSAATRLTNSHAMGSFSGVAGSTVGGRSPSSAGV
LPRPLGQELSSWSPPSGHGPESSPAGRALPLSPCVSGSLVITASLSFSEGHGAQGHQGIP
FSRGGHLLGVAARALARLWELVLGVFNHAVPSASAHPFGARVGRGAACGSATLGPSPLQA
AASASASSFQAPASVETRPPPPPPPPPLPPPAHLGRPPAGPPVLHALSPNAALPPPPTLL
ASNPEPVLLQSLASLPPNQVFLPPASAASLPPANASLSIKLTSLPHKGARPSFTVHHQPL
PRLALAQAAPGIPQASATGPSAVWVSLGMPPPYAAHLSGVKPR
NT seq
5532 nt
NT seq
+upstream
nt +downstream
nt
atggaggctccatcacctgcagtcacgtaccgggcctttgcagaagcaggattcccagcc
aggctggagctcccaggctggagcggttcctggtgggcctgtggagcgtgtcctcagggg
ctcggggacaaacatcacgatgctgctcatgaaatcatcgagaccatccgatgggtctgt
gaagaaatcccggatctcaagctcgctatggagaattacgttttaattgactatgacacc
aaaagcttcgagagcatgcagaggctctgtgacaagtacaaccgtgccatcgacagcatc
caccagctgtggaagggcaccacgcagcccatgaagctgaacacgcggccgtccaccggg
ctcctgcgccacatcctgcagcaggtctacaaccactcggtgaccgaccctgagaagctc
aacaactacgagcccttctcccccgaggtgtacggggagacctcctttgacctggtggcc
cagatgatcgacgagatcaagatgaccgacgacgacctgtttgtggacctggggagcggt
gtgggccaggttgtgctccaggtcgctgccgccaccaactgcaaacatcactatggcgtc
gagaaagcagacatcccggccaagtatgcggagaccatggaccgcgagttcaggaagtgg
atgaaatggtatggaaaaaagcatgcagaatacacattggagagaggcgatttcctctcg
gaagagtggagggagcgaattgccaacacgagtgttatatttgtgaataactttgccttt
ggtcctgaggtggatcaccagctgaaggagcggtttgcaaacatgaaggaaggtggcaga
atcgtgtcctcgaaaccctttgcacctctaaacttcagaataaacagtagaaacttgagt
gacatcggcaccatcatgcgtgtggtggagctgtcgcccctcaagggctcggtgtcgtgg
acggggaagccagtctcgtactacctgcacactatcgaccgcaccatacttgaaaactat
ttttctagtctgaaaaacccaaaactcagggaggaacaggaggcagcccggcgccgccag
cagcgcgagagcaagagcagcgcggccacgcccaccaagggtcccgagggcaaggcggcc
ggccctgccgaggcccccatggactctggtgctgaggaagagaaggcgggagcagccacc
gtgaagaagccgtctccctccaaggcccgcaagaagaagctgaacaagaaggggaggaag
atggccggccgcaaacgtgggcgccccaagaagatgaacactgcgaaccccgagcggaag
cccaagaagaaccaaactgcactggatctcctgcacgcgcagaccgtgtctcagacggcg
gcctcctcaccccaggatgcctacaggtcccctcacagcccgttctaccagctacctcca
agcgtgcagcggcactcccccaacccgctgctggtggcgcccaccccgcctgcgctgcag
aagctgctagagtccttcaggatccagtacctgcagttcctggcatacacgaagaccccc
cagtacaaggccagcctgcaggagctgctgggccaggagaaggagaagaatgcccagctc
ctaggcacagctcagcagctcctcagccactgccaggcccagaaggaggagatcaggagg
ctgttccagcagaaattggatgagctgggtgtgaaggcgctgacctacaacgacctgatt
caagcgcagaaggagatctccgcccataaccagcagctgcgggagcagtcggagcagctg
gagcaggacaaccgcacgctccgcagtcagagcctgcagctgctcaaggctcgctgcgag
gagctgcagctggactgggccacactgtccctggagaagctgctgaaggagaagcaggcc
ctgaagagccagatctcggagaagcagaggcactgcctggagctgcagatcagcatcgtg
gagctggaaaagagccagcggcagcaggagctcctgcagctcaagtcctgcgtgccaccg
gatgacaccctggccctgcacttgcgcgggaagggtgccctgggccgcgagctcgagtct
gacgccggtcggctgcatctggagctggactgcgccaagttctcgctgcctcacttgagc
agcatgagcccagagctctccatgaatggccatgctgccagctatgagctgtgcagcgcg
ctgagccggccctcgcccaagcaggacacgccccagtacctggcctcacccttagaccag
gaggtggtaccctgcacccctagccacggcggccggccgcgcgtggagaaactgtctggc
ttggctgtgcccgactacaccaggctgtccccggccaagatcgtgctgaggcggcacctc
agccaggaccacacgttgccaggcaggccagctgccagcgagctgcacccgagagctgag
cacaccaaggagaatggccttccctaccagagccccagtgtgcccagcagcatgaagctg
agcccccaggacccgcggcccccatcccctgggaccctgcagcttgctggagagaagagc
agtgagaagggcctgagagagcgtgcctacggcagcggcggggagcctatcaccagcctc
cccatcagcatcccgctcagcaccgtgcagcccaacaagctcccggtcagcatccccctg
gccagcgtggtgctgcccagccgcgccgagagggcgagaagcacccccagtcctgtgctg
cagccccgagacccctcgtccacacttgaaaagcatattggtgctaatgcccacagtgct
gggagcaaaagccttgccctggcccccgcagcaggcttctcctatgctggctcagtggcc
atcagcgggaccctggcaggcagcccagcctctctcgcccctggagccgagccagccacc
ttggatgaatcctccggctctgggagtctttttgccactgtggggtcccgcagctccacg
ccacagcatcccctgctgctggcacagccccggaactcgcgcccggcctctcccgcccac
cagctctcctccagtccccggctcggtggggctgcccacggcccgctccccgaggccagc
aagggggacctgccctccgattccggcttctcagatccggagagcgaggccaagaggagg
atcgtgttcaccatcgccaccggcgcgggcggtaccaagcagtcgccttccagcaagcac
agccccctgaccgccagcacccgcggggattgtgcgccaagccacggccaggacaaccgc
aagcgtggccggcggaagcgagcgtcaacggggacgcccagcttgaccacaggcgtgtcc
cccaagcgccgagccctgccatctgtcgccggcctcttcacgcagccttcagggtctcct
ctaaacctcaactccatggtcaataacatcaaccagcccctggagattacggccatctcg
tcccctgagacctccctgaagagctcccctgtgccctaccaggaccacgatcagcccccc
gtgctcaagaaagagcggcccctgagccagaccaatggggcgcactactccccgctcacc
tccgacgaggagccaggctctgaggatgagcccagcagcgcccgaattgagagaaaaatt
gcaacaatctccttagaaagcaaatctccccccaaaaccttggaaaacggtggtggcgtg
gcaggaaggaggcccgcgccggccggcgagccggtcaacagcagcaagtggaagtccacc
ttctcacccatctccgacatcggcctggccaaggccgcggacagccccctgcaggccggc
cccaccctgagccagagctccctgttcgcgttccggcctgccctggaggagacccccgcc
gatgccaagctggccgcccaccccaggaaaggctttcccagctccctgtcaggggccgac
ggactcagccccagcaccaaccctgcgaacggctgcaccttcggcgggggcctggccgcc
gagctgagttcacacagcttcagtgatggtgcttctctcacccacaagggccccgaggcg
gccggcctgagctccccgctgggcttcccctcgcagcgcgccaaggaggcctcggacgcc
aaccctttcctgagcaagaggcagctagacggcctggccgggctgaagggcgagggtggc
cgcggcaaggaggttggggagggaggcctgccgctgtgcggccccgcggacaaaaccccg
ctgcccgctggcaaggccgccaaggcccgggaccgtgagctcgacctcaagaacggccac
aacctcttcatctccgcggccaccgtgccccctgggggcctcctcagcggccccgtcctg
gccccggcggcgtcctctgcaggcggggcagggtcctccgcccagacgcaccggcccttc
ctgggcccgttcccgccagggccgcagttcacgctgggccccatggccctgcaggccaac
ctgggctccgtggccggctcctccgtgctgcagtcgctcttcagctctgtgccggccgcc
gccggcctggtgcacgtgtcgtccgctgccaccagactcaccaactcgcacgccatgggc
agcttttccggggtggcaggcagcacagttggaggtaggtcgccttcctctgcaggtgtc
cttccccgccctctgggccaggagctgagcagctggtccccaccgtctgggcacggtccg
gaatccagtcctgcggggagagcgctcccgctgagtccgtgtgtctcgggttctctggtt
ataacggcgtccctctcgttttcagaaggccacggtgcgcagggtcaccagggcattcct
ttctcccgtggaggtcacctgttaggtgtggccgcccgggctctggcaaggctctgggag
ctggtgttgggtgtctttaaccacgcggtgccttccgcctctgctcatccgtttggagcc
cgtgtcggccgcggggctgcgtgtggcagtgccacgctgggcccgagcccgctgcaggcg
gcggccagcgcctcggcctcttcctttcaggccccggcctcggttgagacccggccgccc
cctccgcctccgcctcccccgctgcccccgcctgcgcacctgggccggccccccgcgggg
cctcccgtcctccacgctctctcacctaacgccgccttgcctcctcccccgacgctgctg
gcctctaaccctgagcccgtgcttctgcagagcctcgcgtccctcccgcctaaccaagtt
ttcttgccccccgcctctgctgcctctctgccgcctgctaacgcctctttgtctatcaag
ctcacctccctcccgcacaagggcgcccgcccctccttcacggtgcaccaccagcccctg
ccccggctggccctggcacaggccgcacccgggatcccgcaggccagcgccacggggccg
tccgctgtgtgggtgtcccttggcatgccgcctccttatgccgcgcacctttcaggggtt
aagccgcgataa
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integrated database retrieval system
