Streptomyces broussonetiae: GQF42_38870
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Entry
GQF42_38870 CDS
T07359
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
sbro
Streptomyces broussonetiae
Pathway
sbro00270
Cysteine and methionine metabolism
sbro00480
Glutathione metabolism
sbro01100
Metabolic pathways
sbro01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sbro00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
GQF42_38870 (egtA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
GQF42_38870 (egtA)
Enzymes [BR:
sbro01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
GQF42_38870 (egtA)
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Motif
Pfam:
GCS2
Lant_dehydr_N
Motif
Other DBs
NCBI-ProteinID:
QHA08439
UniProt:
A0A6I6NC96
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All DBs
Position
complement(8525659..8526999)
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AA seq
446 aa
AA seq
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MSDSNTGGDCTEHRTAVTEPEVEALVRGICFKTGPPRALGVELEWLVHELRAPQLPVTPE
RLQAAYAALRAVPLHSPLTVEPGGQLELSSLPAASLMECIRTVSADLDAVRGVLAEDGLT
LVGIGHDPWHTPRRFLHEPRYDAMETCLDRTGPAGRHMMCTSASVQVCVDAGQEEPGPLG
HARRWWLAHHLGAVLVAAFANSPLIGQEPTGWLSTRQLLWLEIGAGRAGAPRLDGAPRDV
WARHVLDSPVMCVRRDGGPWEVPEGLTFREWTRSRSPRPPTRADLDYHLTTLFPPIRPRG
HLELRMIDAQPGEDGWIVPLAVTAALFDDPGAAETAYRAVKPLAERAMDLPAPHNPLWTD
AARHGLADPELREAAAVCFAAALEALPRLGADAEVTDAVAAFRDRYVARGRCPADDLLDL
RRGLDASRPGGTGGTSTDRRRKDIRT
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atgtccgactcgaacaccggcggcgactgtaccgagcaccgcaccgccgtcaccgagccc
gaggtggaggccctggtcaggggcatctgcttcaagaccggaccgccccgcgccctcggt
gtggaactggagtggctggtccacgagctgcgcgcaccgcagctccccgtgacacccgaa
cgacttcaggcggcctacgccgccttgcgggccgtacccctgcactcgccgctgaccgtg
gaacccggcggccagctggaactgagttcgctgcccgcagcctccctgatggagtgcatc
cgcaccgtctccgccgacctggacgccgtccgtggcgtcctcgccgaggacgggctcacc
ctcgtcggcatcggccacgatccctggcacacgccgcgcaggttcctgcacgagccgcgc
tacgacgccatggagacctgtctggaccgcaccggtccggccggccggcacatgatgtgc
acctccgcctccgtacaggtctgcgtggacgccggacaggaggagcccggcccgctcggc
catgcgcggcgctggtggctggcgcatcacctgggcgcggtgctggtggccgcgttcgcc
aactccccgctgatcggacaggagcccacgggctggctgtccacccggcagttgctgtgg
ctggagatcggcgccggccgcgcgggcgccccccggctggacggcgcaccgcgcgacgtc
tgggcccggcatgtgctggactcgccggtgatgtgcgtccgccgtgacggcgggccgtgg
gaggtgcccgagggactcaccttccgggagtggacacgctcccgctcaccccggccgccc
acccgggcggacctcgactaccacctgaccacgctgttcccgccgatccgcccgcgcggt
cacctggagctgcgcatgatcgacgcacagcccggagaggacggctggatcgtgccgctc
gcggtgacggcggcactgttcgacgacccgggggccgccgagacggcgtaccgggccgtg
aaaccccttgcggagcgggccatggacctgccggccccgcacaacccgctgtggaccgac
gcggcccggcacggcctcgccgacccggagctgcgcgaggccgccgccgtgtgtttcgcg
gcggcactggaggcactgccccggctcggggccgacgccgaggtgaccgacgcggtggcc
gcgttccgggaccgttacgtcgcccggggacgctgcccggccgacgacctgctggacctg
cggcgcggcctggacgcgtcccggcccggcggcaccggcggcacctccaccgaccgccgg
aggaaggacatccgcacatga
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