Streptomyces cadmiisoli: DN051_17785
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Entry
DN051_17785 CDS
T07301
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
scad
Streptomyces cadmiisoli
Pathway
scad00860
Porphyrin metabolism
scad01100
Metabolic pathways
scad01110
Biosynthesis of secondary metabolites
scad01120
Microbial metabolism in diverse environments
scad01240
Biosynthesis of cofactors
Module
scad_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
scad_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
scad_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
scad00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
DN051_17785
Enzymes [BR:
scad01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
DN051_17785
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
DN051_17785
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Gene cluster
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AWW38279
UniProt:
A0A2Z4IZP7
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Position
complement(4151613..4153319)
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AA seq
568 aa
AA seq
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MSPTTLPAAGPEHGHVTFLGAGPGDPGLLTLRAVEALANADVLVAEHDVLDVVRTHARPG
VAVVNTEPGSSSDAVPGTGAPQLTVVDGASTTAAVPAVRDAAHLVMEAARGGRRVVRAVS
GDPGLDTYAADEMLACAAAGVPFEVVPGVAAAVGVPAYAGVPLRDAQGADVRFVDARTAS
DRCWTEVGASDGTVVVSTTLDAVAAAAGELVSAGRKPDTPLTVTVAGTTTRQRTWSATLG
TIAQTLKQAKVLPSPEGGRPVIAVVGERSAAAQRDQLSWFESKPLFGWKVLVPRTKEQAV
SLSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKF
EEYGLDARAFAGIKVAAVGEQTAKALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPI
DRVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTS
SSTVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMSPEPSVHKLAEALADFGMK
RRAAALEAGDPVTRPSERRPGARRRRTT
NT seq
1707 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccacccttcccgccgccggtccggaacacgggcacgtcaccttcctcggt
gccggacccggggatccgggactgctgactctgcgcgccgtcgaggcgctggcgaacgcg
gacgtcctcgtcgccgagcacgatgtgctcgatgtcgtacgtacgcacgccaggcctggc
gtcgccgtcgtgaacacggagccgggttcttcctcggacgccgttccgggcacaggcgcg
cctcagctgacggttgttgacggcgcgtcaacaaccgctgcggtccccgcggtgcgggat
gccgcacatcttgtcatggaggccgcgcgaggcggcaggcgggtcgtccgtgcggtgtcc
ggggatccgggacttgatacgtacgcggccgacgaaatgctcgcctgcgccgcggccggt
gttcccttcgaggtggtgcccggtgtcgcggccgcggtcggcgtgcccgcgtacgccggt
gtgccgctgcgcgacgcgcagggcgcggacgtgcggttcgtggacgcccggacggcctcc
gaccggtgctggaccgaggtcggggcgtcggacggtacggtcgtcgtgtcgacgacgctg
gacgcggtggccgccgccgccggggagctggtgtcggcggggcgcaagcccgacaccccg
ctgacggtgaccgtcgcgggtacgacgacccggcagcggacctggagcgccacgctgggc
acgatcgcgcagacgctgaagcaggcgaaggtgctgccgtccccggagggcggccgaccg
gtgatagccgtggtcggtgagcgctccgccgccgcccagcgcgaccagttgtcgtggttc
gagtccaagccgctgttcggctggaaggttctcgtgccgcgtacgaaggagcaggcggtg
tcgctctccgaccagctgcggtcctacggggccgtgccgcacgaggtgccgacgatcgcc
gtcgagccgccgcgcacgccgcagcagatggagcgggcggtcaaggggctggtgaccggg
cggtacgagtggatcgccttcacctccgtcaacgccgtcaaggccgtgcgggagaagttc
gaggagtacgggctcgacgcccgcgcgttcgcgggcatcaaggtcgccgcggtgggtgag
cagacggccaaggcgctgatcgccttcggcgtgaagccggacctcgtgccgagcggggag
cagtcggccgccggtctgctcgaggactggccgccgtacgacccggtgttcgacccgatc
gaccgggtgttcctgccgcgggccgacatcgccacggagacgctggtcgccgggctgatc
gagctgggctgggaggtcgacgacgtcacggcctaccggaccgtgcgcgcgtcgccgccg
ccggcggagacccgggaggcgatcaagggcggtggtttcgacgcggtgctgttcacgtcg
tcgtccaccgtgcggaacctggtggggatcgccgggaagccgcacaacgtgaccgtgatc
gcctgtatcggtccggccacggccaagaccgccgaggagcacggactgcgggtggacgtg
atgtctcccgagccgtccgtgcacaagctggcggaggcgctcgccgacttcggcatgaag
cggcgcgccgcggcgctggaggccggggacccggtgacgcggccgagcgagcggcggccg
ggagcacgcaggcgccggacgacgtga
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