Streptomyces caniscabiei: IHE65_12455
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Entry
IHE65_12455 CDS
T08931
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
scae
Streptomyces caniscabiei
Pathway
scae00290
Valine, leucine and isoleucine biosynthesis
scae00660
C5-Branched dibasic acid metabolism
scae01100
Metabolic pathways
scae01110
Biosynthesis of secondary metabolites
scae01210
2-Oxocarboxylic acid metabolism
scae01230
Biosynthesis of amino acids
Module
scae_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
scae00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
IHE65_12455 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
IHE65_12455 (leuC)
Enzymes [BR:
scae01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
IHE65_12455 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
IHE65_12455 (leuC)
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GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
WEO23924
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All DBs
Position
complement(2856954..2858378)
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKSGRKVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRVQLETLRANAAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GMTVVCGDSHTSTHGAFGGLAFGIGTSQVEHVLATQTLPLVRPKTMAITVEGELAEGVTA
KDLILAIIAKIGTGGGQGYVLEYRGEAIEKLSMEARMTICNMSIEAGARAGMIAPDQTTF
DYLKGRPHAPEGEDWDAAVAYWKTLKTDDDAEFDAEVIIDGASLSPFVTWGTNPGQGAPL
SASVPDPASYEDASERFAAEKALEYMGLEAGQPLKSIAVDTVFVGSCTNGRIEDLRAAAE
LVKGRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLTDTPAPAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccccaggcc
ttcgacggtctccgcaagagcgggcggaaggttcgccggctcgacctgaccatcgcgacc
gaggaccacaacacccccaccctcgacatcgacaagcccatcgcggacccggtctcccgc
gtccagctggagacgctgcgcgcgaacgccgccgagttcggtgtgcgtctgcacccgctg
ggcgacgtcgagcagggtgtcgtgcacgtggtcggcccgcagctgggtctgacccagccc
ggcatgacggtcgtctgcggtgactcccacacctcgacgcacggcgccttcggcggtctg
gccttcggcatcggcacctcccaggtggagcatgtgctggccacccagacgctgccgctg
gtccgccccaagaccatggcgatcacggtcgagggcgagctggccgagggcgtcaccgcc
aaggacctgatcctggcgatcatcgccaagatcggcacgggcggcggccagggctatgtc
ctggagtaccggggcgaagccatcgagaagctctcgatggaggcccgcatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgaccagaccaccttc
gactacctcaagggccgtccgcacgcccccgagggcgaggactgggacgcggccgtcgcg
tactggaagacgctgaagacggacgacgacgccgagttcgacgccgaggtgatcatcgac
ggcgcctccctgtcgccgttcgtcacctggggcaccaaccccggccagggcgcgccgctt
tcggcctcggtccccgacccggcttcgtacgaggacgcttcggagcgcttcgccgccgaa
aaggccctggagtacatggggttggaggccggccagccgctgaagtccatcgccgtggac
accgtcttcgtaggttcgtgcaccaacggccgcatcgaggacctgcgcgccgccgccgag
ctggtcaagggccgcaaagtcgccgacggcgtacggatgctggtcgtccccggctccgcg
cgggtcggtctgcaggccgtctccgagggcctggacgtcgtcttcaaggaggccggcgcc
gaatggcggcacgcgggctgctcgatgtgtctgggtatgaaccccgaccagctggccccc
ggtgagcgctccgcgtccacctccaaccgcaacttcgagggcaggcagggcaagggcgga
cgcacccacctggtgtcgccgcaggtcgccgccgcgacggccgtcctgggccacctggcg
tcccccgccgacctgaccgacacccccgcgcccgctggagtctga
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