Streptomyces caniscabiei: IHE65_22295
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Entry
IHE65_22295 CDS
T08931
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
scae
Streptomyces caniscabiei
Pathway
scae00280
Valine, leucine and isoleucine degradation
scae00640
Propanoate metabolism
scae00785
Lipoic acid metabolism
scae01100
Metabolic pathways
scae01110
Biosynthesis of secondary metabolites
scae01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
scae00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
IHE65_22295 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
IHE65_22295 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
IHE65_22295 (pdhA)
Enzymes [BR:
scae01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
IHE65_22295 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
WEO25696
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Position
complement(5055327..5056544)
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AA seq
405 aa
AA seq
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MTVESTAARKPRRSAAGKTGTTGSKAAGTTGTRRAAARKPTDAQPELVQLLTPEGKRVKN
AEYDPFVADITADELRGLYRDMVLTRRFDAEATSLQRQGELGLWASLLGQEAAQIGSGRA
TREDDYVFPTYREHGVAWCRGVDPTNLLGMFRGVNNGGWDPNSNNFHLYTIVIGSQTLHA
TGYAMGIAKDGADSAVIAYFGDGASSQGDVAEAFTFSAVYNAPVVFFCQNNQWAISEPTE
KQTRVPLYQRAQGFGFPGVRVDGNDVLACLAVTKWALERARRGEGPTLVEAYTYRMGAHT
TSDDPTRYRHDDERVAWEAKDPIARLRGYLESETDTNEGFFAELEAESEALGRRVREVVR
AMPDPDHFAIFENAYADGHALVDEERAQFAAYQASFADVDEEEGK
NT seq
1218 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggagagcactgccgcgcgcaagccgcgacgcagcgccgcaggcaagaccggc
accaccggcagcaaggcggccggcaccaccggcaccaggcgcgccgctgccaggaagccg
accgacgcccagcccgaactcgttcagctgctgacgcccgagggcaagcgcgtcaagaac
gccgagtacgacccgttcgtcgcggacatcaccgccgacgagctgcgcggtctgtaccgc
gacatggtgctgacccgtcgcttcgacgccgaggccacctccctgcagcgccagggcgag
ctgggcctgtgggcctcgctgctcggccaggaggccgcccagatcggctccgggcgggcc
acccgcgaggacgactacgtcttcccgacctaccgcgagcacggcgtcgcctggtgccgc
ggcgtcgacccgaccaatctgctcggcatgttccgcggcgtgaacaacggcggctgggac
ccgaacagcaacaacttccacctctacacgatcgtcatcggctcccagacgctgcacgcc
accggctacgccatgggcatcgccaaggacggcgccgactcggcggtcatcgcctacttc
ggcgacggtgcctccagccagggcgacgtcgccgaggcgttcaccttctccgcggtctac
aacgcgccggtcgtgttcttctgccagaacaaccagtgggccatctcggagcccacggag
aagcagacccgcgtcccgctgtaccagcgcgcccagggcttcggcttcccgggcgttcgc
gtcgacggcaacgacgtgctggcctgcctcgcggtcaccaagtgggcgctggagcgcgcc
cgccggggcgagggcccgaccctcgtcgaggcgtacacctaccgcatgggcgcccacacc
acctccgacgaccccacccgctaccgccacgacgacgagcgggtggcctgggaggccaag
gacccgatcgcgcgtctgcgcggctacctcgagtccgaaacggacacgaacgagggattc
ttcgcggaactcgaagcggagagcgaggcgttgggaaggcgagtgcgcgaagtggtgcgt
gccatgcccgacccggaccacttcgccatcttcgagaacgcgtacgcggacggacacgcc
ctcgtggacgaggagcgcgcccagttcgcggcgtaccaggcgtcgttcgccgatgtggac
gaagaggagggcaagtag
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