Streptomyces caniscabiei: IHE65_23485
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Entry
IHE65_23485 CDS
T08931
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase subunit PurL
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
scae
Streptomyces caniscabiei
Pathway
scae00230
Purine metabolism
scae01100
Metabolic pathways
scae01110
Biosynthesis of secondary metabolites
Module
scae_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
scae00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
IHE65_23485 (purL)
Enzymes [BR:
scae01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
IHE65_23485 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
WEO25895
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Position
5322834..5325092
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AA seq
752 aa
AA seq
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MSRTPLDTVEHAAATPDVELPWAELGLKKDEYERVVEILGRRPTGAELAMYSVMWSEHCS
YKSSKVHLRQFGEKAPQSDALLVGIGENAGVVDVGQGYAVTFKVESHNHPSYVEPYQGAA
TGVGGIVRDIIAMGARPVAVVDPLRFGAADHPDTKRVLPGVVAGIGGYGNCLGLPNIGGE
VVFDACYQGNPLVNAGAIGVMRHEDIHLAKASGSGNKVILYGARTGGDGIGGASILASET
FDDAKPSKRPAVQVGDPFQEKLLIECTLEAFKEKLVVGIQDLGAAGLSCATSELASNGSG
GMRVTLDDVPLRDSTLSPEEILMSESQERMCAVVEPEKVDRFLEICDKWDVIATVIGEVT
DGDRLEIFWHGGKIVDVDPRTVAHDGPVYERPYARPSWQDELQADDANKLPRPETSEELK
DQVLKLVASPNQASKSWITSQYDHFVQGNTVLAQPEDSGMIRVDEESGLGVAIATDGNGR
YAKLDPYHGAQLALAEAYRNVATTGAKPLAVSDCLNFGSPEDPAVMWQFAEAVRGLADAC
QQLGTPVTGGNVSLYNQTGEVAIHPTPVVAVLGVIDDVARRTPVAFQEEGQLLYLLGDTR
EEFGGSAWSQVVHDHLGGLPPQVDLERERLLAEILISASRDGMIDSAHDLSDGGLIQAVV
ESALLGGKGARLIVPDGLDAFTFLLSESAGRAVVAVPRSEEVRFNDMCGARGLPVTRIGV
VDGDAVEIQGEFTLTLEELRTAHEGTIPALLA
NT seq
2259 nt
NT seq
+upstream
nt +downstream
nt
atgagccggacgcctttggacacggtcgagcacgcggccgcgacccccgacgtcgagctg
ccctgggccgaactgggcctgaagaaggacgagtacgagcgcgtcgtggagatcctcggc
cgtcggcccaccggtgccgagctggccatgtactccgtcatgtggtccgagcactgctcg
tacaagtcgtcgaaggtgcacctgcgccagttcggcgagaaggccccgcagtcggacgcc
ctcctcgtcggcatcggcgagaacgcgggcgtcgtcgacgtcggccagggctacgcggtc
accttcaaggtcgagtcgcacaaccacccctcctacgtcgagccctaccagggcgcggcc
acgggtgtcggcggcatcgtgcgcgacatcatcgcgatgggcgcccgcccggtcgccgtc
gtggacccgctgcgcttcggcgcggccgaccaccccgacaccaagcgcgtcctgcccggc
gtcgtcgccggcatcggcggctacggcaactgcctgggcctgcccaacatcggcggcgag
gtcgtcttcgacgcctgctaccagggcaacccgctggtcaacgccggtgccatcggcgtc
atgcggcacgaggacatccacctcgcgaaggcctccggctcgggcaacaaggtcatcctc
tacggggcccgcaccggcggcgacggcatcggtggcgcctccatcctggcctccgagacc
ttcgacgacgccaagccctccaagcgccccgccgtgcaggtcggcgaccccttccaggag
aagctcctcatcgagtgcaccctggaggcgttcaaggagaagctggtcgtcggcatccag
gacctcggcgcggccggcctgtcctgcgccacgtccgagctggcgtcgaacggctccggc
ggtatgcgcgtgacgctggacgacgttcccctgcgcgactcgaccctctcgcccgaggaa
atcctcatgagcgagtcgcaggaacgcatgtgcgcggtcgtggagccggagaaggtcgac
cgcttcctggagatctgcgacaagtgggacgtcatcgccacggtgatcggtgaggtcacc
gacggcgaccggctggagatcttctggcacggcggcaagatcgtcgacgtcgacccgcgc
acggtcgcgcacgacggcccggtctacgagcgcccgtacgcccgcccgtcctggcaggac
gagctccaggcggacgacgcgaacaagctcccgcgcccggagacgtccgaggagctgaag
gaccaggtcctgaagctggtggcgtcccccaaccaggcctcgaagtcctggatcacctcg
cagtacgaccacttcgtgcagggcaacacggtcctcgcccagcccgaggactccggcatg
atccgcgtcgacgaggagagcggcctgggtgtcgccatcgcgaccgacggcaacggccgc
tacgccaagctcgacccgtaccacggcgcccagctggccctggcggaggcgtaccgcaac
gtcgccaccaccggcgccaagcccctcgccgtctccgactgcctgaacttcggctcgccg
gaggacccggcggtcatgtggcagttcgccgaggccgtacgcggtctggcggacgcctgc
cagcagctgggcaccccggtgaccggtggcaacgtctccctctacaaccagacgggcgag
gtggccatccaccccaccccggtcgtcgcggtcctgggcgtcatcgacgacgtggcccgg
cgcacgccggtcgccttccaggaggagggccagctgctctacctgctcggcgacacccgt
gaggagttcggcggctcggcctggtcccaggtcgtccacgaccacctcggcggtctgccc
ccgcaggtcgacctggagcgcgagcgcctgctggccgagatcctgatctccgcctcccgc
gacggcatgatcgactccgcgcacgacctctccgacggcggcctgatccaggcggtcgtg
gagtcggcgctgctcggcggcaagggcgcgcggctgatcgtccccgacggtctggacgcg
ttcaccttcctcctctcggagtcggccggccgcgcagtcgtggccgtcccccgctccgag
gaggtccgcttcaacgacatgtgcggcgcccgcggcctcccggttacgcgcatcggtgtc
gtggacggcgacgcggtcgagatccagggcgagttcaccctcaccctggaggagctgcgc
acggcccacgagggcacgatcccggcgctgctggcgtag
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