Streptococcus canis: NCTC12191_01279
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Entry
NCTC12191_01279 CDS
T07143
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
scai
Streptococcus canis
Pathway
scai00550
Peptidoglycan biosynthesis
scai01100
Metabolic pathways
scai01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
scai00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NCTC12191_01279 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NCTC12191_01279 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NCTC12191_01279 (murF)
Enzymes [BR:
scai01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NCTC12191_01279 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF760
Motif
Other DBs
NCBI-ProteinID:
VEE25080
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Position
1:1263800..1265185
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AA seq
461 aa
AA seq
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MKLTLHEVAKIVDAQNNVSDLDDVPLNQIEFDSRKITEGDLFLPLKGQRDGHEFIDLAFQ
NGAVATFSEKELPGKPHLLVDDCLKAFQKLAHYYLDKMRVDVIAVTGSNGKTSTKDMIGA
VLSTTYKTYKTQGNYNNEIGLPYTVLHMPEDTEKIVLEMGQDHMGDIHLLSEIARPRIAV
LTLVGEAHLEYFGSRDKIAQGKMQIVDGMNSDGILIAPGDPIIDPYLPKNQMVIRFGDQQ
EIDVTDIQEDKDSLTFKTNVLAEPVTLPLSGKYNAINAMVAAYVGKLLAVTDEDIIEALE
SVQLTGNRTEWKKAANGADILSDVYNANPTAMRLILQTFASISTNPEGKKMAVLADMKEL
GEDSVALHSQLIQQLSPDSIAQLVFYGDDIQELAQLASHLYPAGKVRFFPKNQQEDQFEA
MQEHVQAILNPSDQILLKGSNSMGLARLVDDLVGKKGEESH
NT seq
1386 nt
NT seq
+upstream
nt +downstream
nt
atgaaattaaccttacacgaagtggccaaaattgttgatgcacaaaacaatgtgtctgac
ttggacgacgttcctctgaatcagattgagtttgatagccgaaagattacagaaggagac
ctctttttacccttaaaaggtcaaagggatggtcatgagtttattgatttagcctttcaa
aatggcgctgtcgctactttttcagaaaaagaattaccggggaaaccccatcttcttgtt
gacgactgcctaaaagcttttcaaaagctagcccattattatcttgataagatgcgcgtg
gatgttattgctgtgacaggctcaaatggcaaaacatccaccaaggatatgataggagct
gtcctatcaaccacttacaaaacctataaaacgcaaggaaattacaataatgagatcggc
ttgccttataccgttctccacatgcctgaagataccgagaaaattgtccttgaaatgggg
caggatcacatgggagatattcatctcctatctgaaattgcaagaccccgtattgcagtt
ttgaccttagtcggcgaagctcatttagaatattttggaagccgagacaagatagctcaa
ggcaaaatgcagattgttgacggcatgaattcagatgggattttaattgctccgggagat
cctattattgacccatatcttcccaaaaatcagatggttatccgttttggagatcaacaa
gaaattgatgttactgatattcaagaagacaaagatagcctgacctttaagacgaatgtt
ttggcagagccagtgaccctgcccttatcagggaaatacaatgctatcaacgcaatggtt
gcggcctatgttggaaaattattggcagtaacagatgaggatattatcgaagcgcttgaa
tctgttcagttaacaggtaaccgtacggagtggaaaaaggcagccaatggtgctgatatt
ttatcagatgtttacaatgctaatccaacagccatgcgtctgattttacaaacatttgcc
agcatttcaacaaatccagaaggcaaaaaaatggcagtgctagcagatatgaaagaacta
ggagaagactctgttgctttgcattcacaattaatccaacagttgtcacctgatagcatt
gctcagcttgttttttatggggacgatatccaagaactggcacaattagctagtcacctt
tatcctgccgggaaagtacgcttttttcctaagaatcaacaggaagaccagtttgaagct
atgcaagagcatgtccaagctattctcaatccttctgatcaaatcctcttaaaaggaagt
aactcgatgggcttggctaggttggttgacgatttagtaggcaagaagggggaagagagc
cattag
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