Serinus canaria (common canary): 103820009
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Entry
103820009 CDS
T05755
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
scan
Serinus canaria (common canary)
Pathway
scan00270
Cysteine and methionine metabolism
scan00480
Glutathione metabolism
scan01100
Metabolic pathways
scan01240
Biosynthesis of cofactors
scan04216
Ferroptosis
Module
scan_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
scan00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
103820009 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
103820009 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
103820009 (GCLC)
Enzymes [BR:
scan01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
103820009 (GCLC)
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Paralog
GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
103820009
NCBI-ProteinID:
XP_009092865
UniProt:
A0A8C9NBT8
LinkDB
All DBs
Position
Unknown
AA seq
636 aa
AA seq
DB search
MGLLSQGSPLSWEETRRYAEHVRRHGILQFLHIYRALRDRHKDVLKWGDEVEYMLVKFDH
ENKKVRLLLCGEEVLQTLQDKGEKVNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRQEAASVLKENEAVCTVTSFPRLGCPGFTLPDYMPTPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEAANASKPDYIYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDKDIYEHLI
KEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAV
RQGMFYFRKDICKGGNAVLDGCSSAQNGTCGDAEEYTLMSIDTIINGKEGIFPGLIPILN
SYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYKQDSVITDEMNY
SLMWRCNQIAQGQAECPELLGVGFNKKQSGNKTDSL
NT seq
1911 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcgcagggctcgccgctgagctgggaggagacgcggcggtacgcggag
cacgtgcgacggcacggcatcctccagttcctccacatctaccgcgccctgcgcgaccgc
cacaaggacgtgctcaagtggggcgacgaggtggaatatatgttggtaaaatttgaccat
gaaaataagaaagtgcgtttgttactctgtggtgaagaagttcttcaaacactgcaagac
aagggggagaaggttaaccccaatcacccaacactctggagaccagaatatggaagttac
atgattgaaggaacgcctggacagccatatgggggaacgatgtctgaattcaacactgtg
caagacaacatgaggaaaagacggcaggaggctgcttctgtactcaaagaaaatgaggct
gtttgcacagtgacatcatttccaaggttaggctgtcctgggtttacactgccggattat
atgccaacaccagtagaaggaggagcttcaaaatcactcttttttccagatgaagccatc
aataaacatcctagatttagcacactgacgagaaacattcgacaccgaagaggagagaag
gttgtgataaatgtaccaatatttaaagataagaacacaccatcacctttcattgaaaca
tttcctaatgatgatggagaagcagcaaatgcatctaagccagactacatatatatggat
gctatgggttttggaatgggaaactgctgcctccaggtaacattccaggcttgcagcatt
tctgaagcaaggtatctctatgatcagctagctacgatttgtcccattgtgatggcgttg
agtgctgcgtctccattctacagaggctacgtgtctgacattgactgtcgctggggagtg
atctctgcctctgtggatgatcgaacgcgcgaggagcgagggctggagccactgaagaac
aaccattatagaatcagtaaatccagatatgattccatagacagttatctatctgaatgt
ggtgagaaatacaatgacattgatttgacaatagacaaagatatctacgagcacctaata
aaggaaggtattgaccaccttttggcacagcatattgcacacttgttcattcgagaccca
ttgactttgtttgaggagaaaatacatctagatgatgcaaatgaatccgaccattttgag
aatattcagtctacaaactggcagacaatgaggtttaagccaccacctccaaattcagat
attggatggagagtggaattcagacctatggaggtccagttaacagactttgaaaactct
gcttatgttgtgtttgtggtattgctaacgagagtcattctgtcatataaactggatttt
ctcattcctttgtccaaggtggatgaaaatatgaaggtggcccagaaaagagatgctgta
cgacagggaatgttttacttcagaaaagatatatgcaaaggtggaaatgctgttttggat
ggatgtagctctgcacagaatgggacatgcggcgatgcagaagagtacaccttaatgagc
attgacacaattatcaatgggaaggaaggaatctttcctggtttgatcccaattttgaat
tcctatcttgaaaacatggaggtggatgtggatacgagatgcactatcctaaactatctg
aagctaataaaaaagagagcctctggagaattaatgaccgttgctcgatggatgagggag
ttcatcgcacagcatccggactacaagcaagacagtgtgataactgatgaaatgaattac
agccttatgtggagatgcaaccaaatcgctcaaggccaagcagagtgtcctgaactactt
ggggtaggatttaataagaaacaaagtggaaataaaactgactctttgtaa
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