Serinus canaria (common canary): 103826368 Help Entry 103826368         CDS       T05755                                  Symbol SYNE2 Name (RefSeq) nesprin-2   KO K19346   nesprin-2 Organism scan  Serinus canaria (common canary) Pathway scan04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:scan00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     103826368 (SYNE2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:scan03036]     103826368 (SYNE2) Chromosome and associated proteins [BR:scan03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     103826368 (SYNE2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spectrin_SYNE1 CH KASH Spectrin SYNE1 ATG17_like Motif Other DBs NCBI-GeneID:  103826368 NCBI-ProteinID:  XP_030096668 LinkDB All DBs Position Unknown AA seq 7001 aa AA seqDB search MASQQSSASTEEQASSEIDDLHLTLQVQREFTQKKTFTSWINSILAKHTPPYVVSDLYTD IQQGHLLLDLLEVLSGQHLPREKGFNTFQCRSNIENALTFLKSRSLKLINIHVADIIEGK PSIVLGLIWTIIFHFHIEELARTLACTYNQPSPDCPGAVDSSPKANRSAKKSAKIKERWK MSATKALLLWAKEQCSLHGSVSVTDFKSSWRSGLAFLAIIQTLRPGLVDLEKAKARSNKE NLKEAFRIAELELNIPRLLEPEDVDTVNPDEKSIMTYVAQFLQYSKNLPESEEDMQEKVR EAVGWLAAQEEKLAKLLVETENETYYQKYKEMMSFMETFNQEKIPFLPVLSSKRGEAELS EGQQQMREEWDKVNSQINEWKARLDQMLPSPLDSIEAWLQEVERLQAEDLPDLQDPFKAM SVFREIIGIFKGLMDCFDSHLDTLQSFKNEDEKNMPLVLPEKLEEMKRRFSNIRSTNPST FLEYHYGLCSAIANEVKLKLNIWDVKYGAKESVESLLENWNNFIEEKELETQLDTATHIC EDLKNICGPDLAGDPHEITKLLKTVESKISTCKEYISNVNTTLQKVLSSWSNYTENMHLL KTWLEENRNEDPKEIPAEVLAKRNSIHGSLNEAGNHLIEVSKEQVGSNIAKELKKLNRRW AKFIKRTHFLGEESTNAAEDTTELSGSLEKIEELLRGVDSWATEMGHLLSKISHEEPVKP ELEEHLQSLASRGSSCQDQVVAAEELLQSLRQNVSSQVFQQHSHTTGLEARIKEARDKIE AVMGDLNNILSKSEKKPSEKEALLNFEESQKELEASISKAVQLVSQKLSPEECVSRYEEA FNALDNKVLDKFLKAAELLKNISSDHEKLVVEDDFRRRWEAVRQEIASYVQLIIEREKKK FNATLKKINKQLGKEKKLLSMDKTKGLIKEHEAFFSHEGSMKELNKSLEGLKTLARLSEE TVPGIQTLTADFEKRLEKVQQMVADTYTALLTRVGKGQPPQKGNSIMASENGEESGSSQE IDSLMVQETSRPAADTVLEPDVKHHNGESCADKFEEDGDLAIPALLESFNTQRSNLEELL RHSRDKVASDFTDEIKDTSSLKFKLLELEAMTDMEFRSGWKELEKISSTLENLVSEVQQA ALSEARNKLQSEWEELQDIISIRANSLRAALEIVLETEYQSISVCQLVDEWLKKKYIHPF TLMDRDLAVSELEMLQRSILSQIEECKQLEHLDSSAGDEVNPLDLQAARKVIINCQKQLE EMLHKMQTREAVLKDLEAFLASLRKIQTSITSLPDPPDQPEMQGKALREVAQEVSRLAEE AKCLDERLKSVQICLEDDDHGRKTWCEKLVRALSKKLNAIYDPSSEQVPAEEKDLYKTFS RKNSELLKAIQDLRDRINKIGLKDPTIPAIQKRIKSLTELEKELDRAAAEMKSMQEIANK LPQINEEKAEEANEQCRVTERLWEDTKLLLAECQEQCARVLELLKQYQSCKTSLTSIIQK QEIVLSQQTSYMGKENLNRLIAKIEEAKEEFNDHSEDVDKINQICKNLQFQLNKMRSFEE PPFENEANIIVDRWLDINEKTENYCDNLGRAQALWDKLLNLSDTIEAWANEELKNAEDHC LTEEDLTQLKACLRAQEQKLQKFDTTVAEIEELLNSNEPPLELQVIRSSVVQKMELIKEL LSAKRGTSELTVNTAELKGDLDLAKTQIGMTESLLKALSPSDTLEIFTKLEEIHQKILQQ EHLVALLQEETDCPDVDELNKQLKCVTDLFNSKKHVLQDHFMGVLNRQCKNFNDWFSSTQ LSLKDCFEPSETKAILEERLQRLKHFLTSEGRDRDIQEVKALLNKVKPYLPKASINHLNS RVRDQEAELQRLICKCQKREQELGASLQQLSSLEESSMALKEWLSAQEEKIKEINKDDRD LEDVYKTLLMQRKPFDSLAQLSNSLGEAGLTEYETLSEASNLISRYHALITRVSEMAGNA ERLPVERQNFEDLAQDVSCWIKKLEEALNKMSSQGSELPSDERINQIKEITSLRDEGEAK IQSMVALGDTVLRNEKNKNPEVQQTISELQKKWENLCQLATEYSSPQEQLQCNREQYEQS KEDLKQALMELEKQQQEIFALQPGLEEKQAQLANYADLLQKTEALTSQFSKLKGQKEHLQ GHTVDPCFTEAEWSELKHQHENLLSQLQTIMQTLESPAQGHQQVQDMTTDLSTELKTASE KLAECDGPAMEEPSAEQNQLKSQEQQGPLSRCEDTAKKSLVLGETVKQNTSSPEQEFIED EMETLQSEHKERLEERLENVKQKKENISSEALELKDEFGNEIQKEDKADSMLKKGTQITS DTQISAEETPTAVELKEPLEMRDGQDVNGNMSEKERQNAPVVEESSVLSDSPLQDIHHSK DRLGQAAQEEADKENPDMDRADRFQEDVLDSAVLGGEAELERHQHGVGIEGDESREKTHP AQEAPTDVENQSYREDEGQLQEKSCQKGQVLESAAAEKDGVGSNPPVPAHEDTGAEVVVQ KELFPGVQVNNEYFEEEQKVNELKNEVAELDMVLINEQLKELENLKTELEMWKAKSLCHG EEAVPNGTGSNRAELQTTEPCWDRLLQELEAIKAVKQQQCCLINEYQKNLSAAQSSMKNL STEKDNIKMGPMNNTVLLDKIKACIESLRKERDVLNRLQSQQEVLSQHLTCMDKVLTESQ MRQLEHWWQHMEQAVQKKHDQVVAEIDEFNLLMNKARDIQRLIQEQYLQAELHSSAAGKV KDPLMWTTELQDIKHGLSLLKRKIELQMKRIWSDQEKGALENSIQDLQSKLEALSAQQAP QEDIQTTGPALMKHEMMKRLKENISWVKDSLSHLDQKAALFPSDVKSQIRNCQLMNTDIL SREPVIVSLDYGLQHILPSLEPEEVSDMTFLLQTLKSSYKALVLKSAQRLQHLELQLEER QRLTAEIDKVHSQLCKAELMARPDPNQNSTCSELVSQQAILKEMLKDIQEIEELISSHCK ESQVTAGQLSLSEQLFLIDQLRSLKNRARKTQRQIQSKLHEVEQKAAVSREFAEGIASLQ QDLDDLQDGEMNLKDDELVGAKQGLKDKCKALKEKVLAFQSSLSQVMKYKEIFECVGLKW DSLQMDELQTKFSKIKNKIKEKIMRLENVVREWEKIQGLLDEIQTVTATVRKEANILNDS SSSSPAENVISAQILLQAVQQILCLTQEAANQINKNEVFDTSFKESKRKEIKSLEKNVEE LKHFLQNLVSGLQSVNKEGSQDEEENIFHIIRHIQLELQQPLVIDINTMQDEKLRWEAIQ NMMEGKFSALKCIMEKEKEKQEEKSPAAAIKIKLETLQGCEAQVKADIAARVNALEEACR AGELYTKALQRAARFLEDCEAPAQAAAAELCGSVEICQTPHWKEEEFNSAKADLENLHSK LKNLVKPEDKVCLENAVRELVERSLALRKKVQRKEADEQRYFEKHKSYTETKDKVCDNLR KLEKMLRQSLSKIPVSYKEALEHLEESKILVSSIDSAEEDLVKLRQISGEMMRLCRGSDR ALGRIVTVLWENWLGLLEAAKGLEITCEELKQEWKFINEELERETIILDKLQEEQPESLK EKEKATREELVELLDFVNSFEENINQQQLLLLLLLHRIRNILSAPEDAEREAALPALAEI KAMQERCKKLYKKAQDHKDSVKAEIQERNKVTEEISAVTNALENAASVLLQDADGKAEQL EELQSVIDRERQALEDIMEKLRIKYSEMYSIVPAEIETQLEDCKKVLHDLEEKVSSEILQ NSPQYVLKRKAETINNGLQAIEKMLQQKSENIAKAKEVQKQIWDMLDLWHYKLNELDAEV QDIVEQNSCHAQELMDILVAPLQQYQQVSQRAERRTAILNKATNKMEEYEELLKNVKDWI ESTNSLLRADAQHDSAKSLHKYTDELQMALEDSEQKQNLLHGIFMELEELSPVFETDSVM QQLNEIDVQVAALQHEIAEILPQILHVADELDAIESHVKVFEKDVAEMKTILSSEDLLEF SPKDQLKHGQVILEHVGPMQKTIVHIQSYEDALQLPGLKMQPFSVFQRARQLLRELKKLE KITKEQNELLEETVKKTEECEQEIEKLKQLLKNNLGEISHEDQPEAQKTPCPEGEMEAVK EEIIKLCQRKEDFLTRMKNSMSELHQCLQQEVPEAADEPPASVLAQSHLIGTDVSPQQLK KRGVISLLPSLDEESEDCSLHSKGSTATEKDASLWPSEGDDERLKEDSATSWSSGTLSDG IVQDEDVLTESHSKHDEETSLPTLEGPKGPGTADGSLAMSQQLPPVPNAALGSQTALDGG RPEPESILLLCQAQVAELEQWLAKTKMSLGSAPQTPQRQQMVEPQLADCQVRLSEIEQKV LSLLEDCGDSADYQQKTEALSLKLKEVKRNLENVQMMLQDKHSEEQVPSRERMDPEPLEI LHSDGFSTSQLPLAQQPWQNGLQQPQDLKLKAAEQKSLIDFIESCVEKMQPQLEDSVTPK SESSSGESDSKSKQADTTLAPKDQMGNKWQYLQQELSSKMKSPLCQLVEPQITTKMNMLP RGTFSGAGTPTVEELKTYTVQLGDLSQEANVVHAQDNVAEEVSSNLDRKLFELLLAISRC LNNMEEMLNTSVLSTEEAAVQQALYETLSVELQKLHADLSDKKDDLLKSISCAGGSTDVF CECFNNLQARLEQTQAATASRSSSMKAGLDHNSNYLNQTRLLYDQLTEKKAALQQCLNEL RGHNVSEQLQKIGDFAVELQNFENQVSKLRGHGERLQLPITLIQEAYKLEDVLDDMWGIL KAKYVELNSPAISESQYEDLLHGFAELVAIGREKMAQDPKHLTKNRAALQSHLKNHKDFF HNLMTRMAYMEAFSKRVSPSVLQKREEFWRELVNEVKLLEQKACQYGIHLESLLKDWVVF DEECLVFNKELEALASVLPSVSLVEESEERLMERIALLEKIKSSVDEKHARLYQMVKEGK KLLSAVNCPEIRSQIGKLEEQWLSLTKKVGHELHRLQTLLKLLVSYNRDSEELMKWLDSA QQRMNFWKEQSLNVSQDLATIRDSISSLFTFSKEVDEKSSLKSSVVSTASQLLHVKQADT ATLRSFLAKFEQKWGELITQLPAIQEKLHQLQMEKLSSREAIAELMAWLDHVEQQQEREE PVNSQHSAAQVKTLLQKYKEYMMEMNFKQWMVDFVNQSLLQMSTCDVESKRYERTEFAEC LGEMNLRWHRLQASLNRKIQDLEHILEDITENENKAQTLHSWLEAQSDRLRSLQTPASLI SAQNTLDDCKELENQLVAKSKTLDELKESLVSDGSAEETPEAQSLRIAELCEMKDSIVNQ VAQLKASMESILEQWRAYDEIYAEVSLMTTRYLYCIDQCKPSEEEASLEALKKQVKTLQA LQDESENSEESWAKLQAAASTLKKSCSPSFAEIIDQKCMEAHTRWNSVNEDITDQLRAAQ AALQLWEPFDALCSETAAKLQQYSQQCAQLLDAHMPEENSIETLEQRIQEIKNLQHGLQN LAGCRTQIYLQADRIKQQAGTAAEATLMEKLQPLQRATYLEKMLQRKLDELQFNLLQLED FNNCLETLEGRVKNCTDTFDSLCLEEGDNSELLLKQTLELAALSPSIESLNEASIKLPLS DFSLKKMQSLTRQWSQKTAAALECCSMLEGTQNDEKKFFQKCEKWMKFLEKMKEALKTDI PGRFEELQEQQRVYEMLQTEISINQQTFNSIIEKVLLSLESGEAEKRTEFISKLTLLKEQ WQNVIRMVQQRKKDIDALVSQWQLFRSSLQSLSRFLDDTNSFLAAVKSQDCYSLYQLRNV IHDFKSKAVILQRWQAMYTLVIDVGEKLRAVSDPSTSAALQEELSHLQQRWGKTQALLEK KKMQFSGTLQTCDRFEKQTKELESRLQELKEKVKDPLPVEHEELHKAKEHIKELEQSLAD WAHDMKELQAMKVELAHLILTEDMMVLKEQVEHLHRQWEELCLRVSLRKQEIEDRLNAWI VFNEKNKELCSWLVQMESKVLQTADVSIEDMIDKLQKDCMEEITLFSENKLHLKQMGDQL IKASNKSRVAEVDDKLNKINDRWQHLFDVIGARVKKLKETFAFIQLLDKNMSNLRTWLAR IESELSKPVVYDICDDQEIQKRLAEQQDLQRDIEQHTAGVESVFQICEVLLHDSDACANE TECDSIQQTTRSLDRRWRNICAMSMERRMKIEETWRLWQRFLDDYSRFEDWLKASENIAA RPNSSEVLYTHAKEELKKFEAFQRQIHERLTQLELINKQYRRLARENRTDSASKLKQMVH EGNQRWDNLQKRVASILRRLKHFTNRRDEFEGTRESILVWLTEMDLQLTNVEHFSKSNFD DKMRQLNGFQQEITLNTNKIDQLIVFGEQLIQKSEPLDAILIEDELEELHRYCQEVFGRV ARFHQRLTSRDPGLDDEKDNSENETDQEDSREIQNDPWHKKAITEGPSSTQSLCHLMPPT QGHERSGCETPVSVDSIPLEWDHTGDVGGSSSHEDDEEATYYSALSDVEITENPEAYLKM TTKTLKASSGKSVSEARPWHSPGSPVCRKHRYNQAEMVGNVLSGPETSTPFKPAYVKQLS SASSSSSKEKIPSANMSDEEPQDDQELVNLAATEKQSGIIDRWELIQAQDLRNKLRMKQK LQQWQQLDSDLSDISAWLDKTEQELEELQKVKLPTSMQALEQKVKKLKDMLKAFDSYKAV LLSANLSSKEFQKADSTEFKELQNRLRKVNLHWEKANRALDNWRKGLQQALLQCQDFQDQ SQKLILWLASAESRRNEAQITDPNADLNTILECQKELMQLEKELLEQQLNVNSLQELTAY LLLKSDGDYIEEEEKVHVIGTKLKQLIEQVSHDLKTIQGNLDTKTFLLVPDDLDSGVYNP EEEKSSPAVKKMALRRAADSRNGSSTRSESHSEPVQTAPRSPSFFYRVLRAALPLQLFFL LLLLLACMIPSSEEDYSCTQANNFARSFYPMLRYTNGPPPT NT seq 21006 nt NT seq  +upstreamnt  +downstreamnt atggcatcacagcagtcatctgcatcaacagaggagcaggcttcctctgaaatagatgat ctccatctaacgctgcaagtccagcgagagtttacacagaagaaaaccttcactagttgg ataaattcaatattggcaaagcatacccctccttatgttgtctcagacctgtatacagac atacagcagggacatttgcttctggatctgttggaagtgctttcaggtcaacatctgcca agggaaaaaggatttaataccttccagtgtagaagtaatatagaaaatgctttgacattt ttaaagagcagatcactgaagctcataaatattcatgtagctgacattattgaaggaaaa ccttccattgtgcttggcctaatctggaccattatatttcattttcatattgaagaactg gccaggacacttgcctgtacctacaatcagccttcacctgattgtccaggtgctgttgac tcctctccaaaggcaaacagatcagccaaaaaaagtgctaaaattaaggaacggtggaag atgtctgctacaaaggctcttttgttgtgggcaaaagaacagtgttcattgcatggctct gtcagtgtcactgatttcaagtccagctggcgaagtggactggcctttttagccatcatc cagaccttgaggccaggtctggttgatttggagaaggcaaaagccagaagcaataaagaa aacctgaaagaggctttcagaattgcagaactggagctgaatatcccacgacttctggag cctgaagatgttgacactgtgaatccagatgaaaaatcaatcatgacttatgtggctcag tttctgcaatactccaagaatttgcctgagtctgaagaagacatgcaggagaaagtaaga gaggctgtgggctggttggctgcacaggaggagaagttagcaaaactactggtggaaaca gagaatgaaacatactaccagaagtacaaagaaatgatgtcatttatggaaacatttaac caagagaaaatcccctttctgcccgtgttgtcatcaaaaaggggtgaagctgagctgagt gaaggccagcagcagatgagggaagagtgggataaagtcaactctcagattaacgagtgg aaagcaaggctggaccagatgttgccctcccctctggatagcattgaggcttggctccag gaggtggaacgtctgcaggcagaagatttgcctgatttacaggacccattcaaagcaatg tctgtcttcagagaaataattggaatatttaagggcttgatggactgttttgattctcac ttggacacccttcagtcatttaagaatgaagatgagaagaatatgccactagtcttgcct gaaaaattagaggaaatgaaaagaagatttagcaatattcgttctacaaaccccagcact tttcttgagtaccactatggactgtgctcagccattgccaatgaggtgaagttaaagctc aatatctgggatgtgaaatatggggcaaaagagtctgtggagtcactgctggaaaattgg aataatttcattgaagaaaaggaacttgaaacacaactagacactgctacccacatctgt gaagacttgaagaacatatgtggtcctgacctggctggagatcctcatgaaatcaccaaa cttttgaagacagtggagtcaaagatttctacatgtaaagagtatatttccaatgtaaac accaccctacagaaagtcctgtcctcctggagtaattacacagaaaacatgcacttattg aagacatggttggaagaaaacagaaatgaggatccaaaagagatccctgctgaggtcctg gcaaagaggaattcgattcatggttccttaaatgaagctggaaaccatctcattgaagtc agcaaagagcaagttggatcaaatattgccaaagagctgaagaaactgaacaggagatgg gcaaagttcatcaagaggacacactttcttggagaagagagcacaaatgctgctgaagat accactgagctttcagggagcctggagaaaattgaagagctccttagaggggtggacagc tgggcaacagagatgggacatctccttagcaagatcagccacgaggagcctgtgaaacct gagctggaggaacatttgcagagtttggcttcaagaggatcctcgtgccaagaccaagtt gtggcagcagaagagctactgcaatccctgaggcaaaatgtttcgagtcaggtgtttcag cagcattctcacaccactgggctggaggcacgaattaaagaagccagagacaaaatagag gctgtcatgggtgacctgaacaacatcttgtccaaatctgagaagaagccctcagagaag gaggctttgctcaattttgaagaatcccagaaagaacttgaggcttccatttcaaaggct gtgcaacttgtcagtcaaaaattaagtcccgaagaatgtgtttcaagatatgaggaagct tttaatgctctggacaataaagttcttgacaaatttttgaaagcagctgaactgctgaaa aatatttcatctgaccatgagaagctggtggtggaagatgattttcgtaggagatgggag gcagttcgtcaggaaattgcatcctatgtccagctcatcatagaaagggaaaaaaagaaa tttaatgcaactttaaaaaaaatcaataagcagttaggcaaagagaagaaactgctaagt atggataaaaccaaaggactcatcaaggagcatgaggcctttttttcacatgaaggcagc atgaaggagcttaacaagtctttggaaggccttaaaacattggcaagactctcagaagaa actgtcccagggatacagacactcactgcagactttgaaaaaaggctagaaaaggttcag caaatggtggcagacacttacacagcactgctgactcgtgttggaaaaggacagccccct cagaaagggaactccattatggcttctgagaatggagaagagtctggttcttctcaagaa attgacagccttatggtacaggagacatcaagacctgctgcagatacagttttggaacca gatgtgaagcaccacaatggagaaagctgtgcagacaagtttgaggaagatggtgatttg gccataccagctctgttagagagctttaacacacagagaagtaacctggaggagcttcta cgacacagcagagataaagtagcatctgactttactgatgaaataaaagacacttcatcc cttaagtttaagctgcttgaactagaggcaatgacagacatggaattcaggtctggttgg aaagaattggaaaagatctcatctaccttagaaaatcttgtgtctgaagtgcagcaggct gctctctctgaggcaagaaacaagctacaaagcgagtgggaagaacttcaggatattata agtatcagagcaaattctttaagggctgctctggaaattgttttggaaacagaatatcaa tccatctctgtctgtcaattagtagatgaatggctgaagaaaaagtacatccacccgttt actctgatggacagggaccttgctgttagtgaactggagatgctgcagagatctatatta agtcagattgaagagtgcaaacaattggagcacctggacagttcagcaggggatgaagtt aatccattagacctgcaagctgcaagaaaagttataattaactgtcaaaagcagcttgaa gaaatgctccataaaatgcagacccgtgaggctgtccttaaagatctggaagcttttttg gcctccctgaggaagatccagacttccatcacatctctcccagatccccctgatcaacct gaaatgcagggaaaagctttgagggaggttgcacaggaagtttctcgtctggcagaagag gccaaatgtttggatgagcgcctgaagagtgttcaaatctgtctggaagatgatgatcat gggagaaagacttggtgtgaaaaacttgttagggctttatctaaaaagctaaatgccatt tatgatccctcaagtgagcaggtgcctgcagaagaaaaagacttatacaagactttttcc agaaaaaacagtgaactccttaaagccattcaggatctacgggacagaatcaacaaaata ggcttgaaggatccaacaattccagctattcagaaaaggataaaatcattaacagaattg gaaaaggaattggatcgtgctgctgctgaaatgaaatctatgcaagaaattgctaataag ctcccacagatcaatgaggagaaagcagaggaagcaaatgagcagtgcagagttacagag aggttatgggaggatacaaagctcttgcttgctgaatgccaggagcagtgtgcaagggtt ctggagctcctgaagcagtatcaaagctgcaaaacgagtctgaccagcatcatccagaaa caggagattgtgctttcccagcaaacttcttacatggggaaggagaatttgaacagacta atagcaaagattgaagaggcaaaagaggaatttaatgatcactctgaagatgtagacaaa ataaatcagatctgcaaaaacctgcaattccagctgaataaaatgagaagctttgaggag cctccgtttgagaatgaggctaacattattgtggacagatggctggatatcaatgaaaag actgaaaattactgtgataatctggggagagctcaggctttgtgggacaaactcctgaat ttatctgacacaattgaagcttgggcaaatgaagaactcaagaatgcagaagaccattgc ctgactgaggaggacctcacccagttgaaggcatgcttacgggcccaagagcagaaactc caaaaattcgacaccacggtggctgagatagaagaactcctgaatagtaatgaacctcca ttggagctacaggtcatcagatcatctgttgtgcagaaaatggagctaataaaagagctc ttgtcagccaagcgagggaccagtgaactcactgtgaatacagcagagctgaaaggagac cttgatctggccaagacacagattggaatgactgaatcacttctcaaagctttatctcct tcagacaccttagagatctttactaaactagaggagatacaccagaaaattctgcaacag gagcaccttgtggcattactccaggaagagacagattgtcctgatgtggatgaattaaat aagcagcttaaatgtgtcactgatttattcaatagcaagaaacatgtgcttcaagatcac tttatgggtgttttgaatcgtcagtgcaagaattttaatgactggttcagcagcactcag ctgtctctgaaggactgctttgagccctcagaaacaaaagccatactggaagaaagacta cagaggctaaagcacttcctaacatctgaaggcagagatagagacatccaagaggttaaa gctttactgaataaagtgaagccttacttgcccaaagccagcattaaccacctcaacagt cgtgtgagggatcaggaggcagagctgcagaggttgatctgcaaatgtcagaaaagggaa caggagcttggtgcctctctccagcagctcagcagccttgaagaaagcagcatggctttg aaagaatggctctctgctcaggaggaaaaaataaaagagatcaataaagatgatagagac cttgaagatgtctataaaacactgttaatgcagaggaaaccatttgactccctggctcag ctgtcaaattccttgggggaggctgggctgacagaatatgaaaccctttcagaagccagt aaccttatcagcaggtaccatgcactgataacacgtgtcagcgaaatggcagggaatgct gagagacttccagtggaaagacaaaattttgaagaccttgcccaggatgtttcttgctgg atcaaaaagcttgaggaggctcttaataaaatgagttcacaaggaagtgagttgccatca gatgaaaggattaatcagataaaggaaatcacaagtctcagagatgaaggtgaggccaaa atacagagcatggtggctctaggagacactgtgttgagaaatgagaaaaataagaatcca gaggttcagcagactatttctgagctccagaagaagtgggaaaacctctgtcagctggcc actgaatatagcagccctcaagagcaacttcagtgcaacagagagcaatatgagcaaagc aaagaagatctgaaacaggctctaatggaactggagaaacagcaacaggagatttttgcc cttcagcctggtttggaggagaagcaagctcagctggcaaactatgctgacctcctgcag aaaacagaagccttgacctcccaatttagcaaattgaagggccagaaggagcatctgcag ggccacactgttgatccctgcttcacagaggcagaatggtcagaattaaagcaccaacat gaaaatctgctcagccagctccagaccatcatgcagacattggaaagccctgctcaaggg caccagcaggttcaggatatgacaacagacctgagcactgagctgaaaactgcctctgag aagcttgctgagtgtgatggtccagcaatggaagaaccatcagctgagcaaaatcagttg aaatcacaggaacaacagggacctcttagccgatgtgaagacacggcaaagaaaagtttg gttttaggagaaactgttaaacaaaacacctcttcaccagaacaggagtttattgaggat gagatggaaacacttcagagtgaacacaaagaaagattggaagaaagacttgaaaatgtc aagcaaaagaaggaaaacatttccagtgaagcccttgagttaaaagatgagtttggtaat gaaatccaaaaggaagataaggcagattcaatgctgaagaaagggacacagatcacttct gatactcaaatctctgcagaggagacccccacagcagtggagctaaaggagcctttggaa atgagagatggtcaagatgtaaatggaaatatgtctgagaaagagaggcagaatgctcca gttgtggaggaaagcagtgtactgtcagacagcccattacaggatatccatcacagcaag gacagattggggcaggctgctcaggaggaggctgataaggagaacccagatatggacaga gctgacaggttccaagaggatgttctggacagtgcagttctgggaggtgaagcagaactg gaaagacatcagcatggtgttggtattgaaggtgatgaatctagggaaaaaacccatcca gcacaggaggcacctactgatgttgagaatcaatcatacagagaagatgaggggcagctt caagagaagtcgtgccaaaagggtcaagtcctggaatctgcagcagctgagaaggatggt gtgggatctaatcccccagttcctgcacatgaggacacaggtgcagaagtggttgtccag aaggaactatttcccggagtgcaagtaaacaatgaatattttgaagaggaacaaaaggtc aatgagctgaaaaatgaagtggctgaactggatatggtgcttataaatgagcaactaaaa gagctggagaatttaaaaactgagctggaaatgtggaaagcaaagtctctgtgccatggt gaagaagcagttcccaatggaacaggatcaaacagagcagagctgcaaaccacagagccc tgctgggacaggctgctccaggaactggaagccattaaggcagtgaagcaacagcagtgc tgtttaattaatgaataccagaaaaatctttctgctgcacagtcctccatgaaaaatttg tcaacagaaaaagataacataaaaatgggtcctatgaacaacacagttcttctggacaaa attaaggcatgcatagagtccttacggaaagaaagagatgtcttaaaccggttgcaaagt cagcaagaagttttatctcagcatttgacatgcatggataaagtgttgacagagagccaa atgaggcagctggagcactggtggcaacacatggaacaagcagtgcaaaagaaacatgat caggttgtggcagaaattgatgaatttaacctgctaatgaataaagcacgggatattcag aggctgatacaggaacagtatttgcaagcagagttacattcttcagctgcaggaaaagtc aaagaccctctcatgtggaccacagagctacaggacattaaacatggtctttctctatta aaaaggaagattgagctgcaaatgaaaagaatttggagtgatcaagagaagggggctttg gagaactctatacaggatttgcagagcaaactggaagcattatcagcccaacaagctcct caagaggatatccagaccactggtcctgctctcatgaaacatgaaatgatgaagaggcta aaagaaaatatttcctgggtcaaagactcactgtcccaccttgatcagaaagcagcactt ttccccagtgatgtcaaatcacagatcagaaattgtcagcttatgaacacagacatccta agcagagaacctgtgattgtatccctggattatgggctccagcacatccttcccagcttg gagccagaggaggtctctgatatgaccttccttttacaaacattgaagagttcatacaag gctcttgttttaaaatctgctcaaagattgcagcacttggagctccagctggaggagagg caaagactcactgcagaaatagacaaagttcactctcagctttgcaaagctgagctgatg gccaggcctgacccaaaccaaaacagcacctgctcagagctggtgagccaacaagccatt ctgaaggagatgctaaaggacatacaggaaatagaagagcttatctcatcccactgtaaa gagagtcaggtcacagctgggcagctgagcctgtctgaacaactcttcttgattgatcag ttaaggagtctgaagaatagagcaaggaaaacacagaggcaaattcaaagtaaacttcat gaagtagaacaaaaggcagctgtctccagagagtttgctgaaggaatagcttcattgcag caggatcttgatgacctgcaggatggtgaaatgaacctgaaagatgatgaattagtaggt gccaagcagggactgaaggacaaatgcaaagcactgaaagaaaaagtgttagcttttcag tcaagtttgtcacaagtaatgaagtacaaggaaatatttgaatgtgtaggtctgaaatgg gactcactgcagatggatgaattgcaaactaaattttctaaaattaaaaataaaattaaa gagaaaataatgcgcttggaaaacgttgttagggaatgggaaaagattcaaggattgcta gatgaaatccagactgtgacagccactgtcagaaaagaagctaatattctaaatgatagc tccagctcttctcctgctgagaatgtcatatctgcacagattctattgcaggcagttcaa caaatcttgtgcttaacccaggaggcagcaaatcaaataaacaaaaatgaggtctttgat acatcattcaaagaatctaagaggaaagaaataaagagcctggagaaaaatgttgaagaa ttaaagcattttcttcaaaacttggtctctgggctacagagtgtaaacaaggaaggtagc caggatgaagaagaaaatatattccacatcataaggcatattcagttagaactccagcag cctcttgtgatagacataaatacaatgcaggatgaaaagctgcgatgggaagcaattcag aatatgatggaaggaaagttttctgctcttaaatgtataatggaaaaagagaaggaaaaa caagaagagaaatctcctgctgctgctataaaaataaagttagagacactgcaaggctgt gaagcacaagtgaaggcagacattgctgctcgtgttaatgctctggaggaggcctgtagg gctggtgagctttacaccaaggcccttcagagggctgccaggttcctggaggactgtgaa gctccagcccaggctgctgcagcagagctctgtggctcagtggagatctgtcagactcca cactggaaggaagaagagttcaactctgcaaaggctgacttagaaaacctgcactccaag ctgaaaaacctagtgaagccagaagacaaagtatgtctggaaaatgctgtaagagaactg gtggaaaggagtttggcattaaggaagaaggttcaaagaaaggaagctgatgagcagagg tattttgaaaaacacaaaagctacacagaaaccaaagataaagtgtgtgataatcttaga aaactggaaaagatgcttagacagtctttgtctaagattccagtgtcttataaagaggct ttggagcatttggaagaaagcaagattttagtctccagcattgactctgctgaagaggat ctggtgaagctgagacagatctctggagagatgatgaggttgtgcagaggaagtgacagg gccctgggcaggattgttacagtgctgtgggaaaactggctgggtttgcttgaggcagcc aaagggctggaaattacctgtgaagaactaaagcaggaatggaaattcatcaatgaagag ctggaacgagaaacaatcattctggataagctccaggaagaacagccagaaagccttaaa gagaaggaaaaggccaccagagaggagctggtggagttacttgattttgtgaactcattt gaagaaaacatcaaccagcaacagctgctcttactcttgctccttcaccggataagaaac atcctgagtgcccctgaagatgctgagagggaagctgccctccctgccttggctgagata aaggcaatgcaggagcgctgtaagaagttgtacaaaaaagctcaagaccataaagattct gtgaaagctgagattcaagagaggaacaaggtcactgaagaaataagtgctgtgacaaat gcattagagaatgctgcatctgtgttactgcaggatgctgatggaaaggcagaacagctg gaggagcttcagagtgtgattgacagagagagacaagctctggaggatatcatggagaaa cttcggatcaagtattctgaaatgtactcaatagtccctgcagagattgaaacacagctg gaggactgcaagaaagtattgcacgacctggaagagaaggttagctctgaaatcctgcag aactctcctcagtatgtgctgaaaagaaaagcagaaactattaacaatggccttcaagct attgaaaagatgttacaacagaagagtgaaaacattgcaaaagccaaagaagttcagaag caaatttgggatatgctggacctgtggcattacaaactcaatgagctggatgcagaagtg caggacatagtggagcagaattcctgccatgcacaggagctgatggacatcctggtggcc cccctgcagcagtaccagcaggtctcccagcgtgctgagcgcagaactgccattctcaac aaggccaccaacaagatggaagaatatgaggagctcttgaagaatgtgaaagattggata gaaagcaccaacagtttgctaagagctgatgctcagcacgactctgcaaaaagcttacac aagtatactgatgagctccagatggctttggaagactcagagcaaaagcaaaatcttctg catggtatcttcatggagctggaggagctgtcaccagtctttgaaactgacagtgtaatg caacagctgaatgaaatagatgttcaagtagcagctttacagcatgagattgcagagatt cttccacaaatcctgcatgtggctgatgagttggatgccattgaatcacatgtgaaagtg tttgagaaggatgttgcagaaatgaagacaatcctgtcatcagaagatctgttagaattt tctcctaaagaccaacttaaacatggacaggttatacttgagcatgttggtcccatgcag aaaactattgttcatatacagtcctatgaagatgctcttcagctgccagggctgaaaatg caacctttctcagtcttccaaagagcaagacaactcttgagagaactgaagaaattagaa aaaattactaaggaacaaaatgagctactggaggaaactgtaaagaaaacagaagaatgt gagcaagaaattgaaaagttgaaacaactcctaaagaacaatttgggtgaaatatcacat gaagatcaaccagaggctcagaagactccttgtccagagggagaaatggaagctgtaaaa gaagaaatcataaagctgtgccaaagaaaggaagatttccttaccaggatgaagaattcc atgtctgagcttcaccagtgcctacagcaagaagtgcctgaagcagcagatgaacctcca gcctctgtattagcccagagtcacctgattgggactgatgtttcacctcagcagttgaaa aaaagaggagtgatatctcttctgccttccttagatgaagaatcagaagactgttcttta cacagcaagggaagtacagccacagagaaagatgcaagcctttggccttcagaaggagat gatgaaaggctcaaggaagacagtgcaacctcctggtcttctggtaccttgtcagatggc attgttcaggatgaggatgttttaactgaatcacacagcaaacatgatgaggaaacatct ctgccaactttggagggccctaaaggtcctggcacagctgatggcagtctggctatgagc cagcagctgcctccagtgcccaacgctgccctgggctcgcagacagcgctggatggaggg aggcctgagccagaatccatcctcctgctgtgccaggcccaggtggcagagctggaacaa tggctagccaaaactaaaatgtccctgggctcagcccctcagaccccccaaaggcagcag atggtggagccacagcttgctgattgccaggtgaggttatcagagattgaacaaaaggtc ctttctttactggaagattgtggagatagtgcagactaccaacaaaagacagaggctctt tccttgaagctgaaggaggtgaagcgcaatttggaaaatgtccagatgatgcttcaagac aagcacagtgaagagcaggttcccagcagggagaggatggacccagagcccctggagatc ctgcactctgatggtttcagcacatcccagctgccccttgcccaacagccttggcaaaat gggctccagcagccacaggacctgaaattaaaagcagctgagcagaaaagcctcattgac tttattgagtcgtgtgtggaaaaaatgcagccacagcttgaggacagcgtgactccgaaa tcagaatccagcagtggagaatctgactcaaagagcaagcaggctgataccaccttagct ccaaaggatcaaatgggtaataaatggcaatatttacaacaggaactctcatcaaagatg aaatctcctctctgccagcttgtggaacctcagatcacaacaaagatgaacatgctgcct cgaggcacattctcaggtgcaggaaccccaactgtggaagaactgaaaacttacactgtc cagctgggagacctaagccaagaagcaaatgtggtgcacgcacaggataatgtggcagag gaagtctcttccaatttggacagaaagttgtttgagctgcttctggcaatcagccggtgt ttgaataacatggaagagatgctgaacacctccgtgctctccactgaagaggcagctgtg cagcaggctctctatgagactctgtctgtggagctgcaaaaacttcatgctgatctgagt gacaaaaaggatgatcttctgaagtccatcagctgcgctggtgggagcacagatgtgttc tgcgagtgctttaacaacctgcaggcacggctggaacaaacccaagctgccactgcttca aggagcagctccatgaaagctggcctggatcataatagcaattacctgaatcaaaccagg ctgctctatgatcagttaactgagaaaaaagctgctctgcaacaatgcttgaatgaacta cgtggacataatgtttctgaacagcttcagaaaattggtgactttgctgtggagctgcaa aactttgaaaaccaagtatcaaaattgagaggccatggagaaagattgcagctacctatc accttaatccaggaagcttataaattagaggatgttctggatgacatgtgggggattctg aaagcaaagtatgtggagctgaactcccctgccatcagtgaaagccagtatgaggacttg cttcatgggtttgcagagctggtagctattggaagagagaagatggcccaagatccaaag cacttaacaaagaacagagcagctctgcagtctcacctgaaaaatcacaaggattttttc cacaacctcatgacacgtatggcttacatggaagcattttccaagagagtgagtccttct gtcctgcaaaagagagaggaattctggagagagctggtgaatgaggtcaaattgctggag cagaaggcctgccagtatggtatacacttagagagcctgctaaaggactgggtggtattt gatgaggaatgcctggttttcaacaaggagttagaagcacttgcctctgtgttgccttct gtcagtttggtagaagaatctgaagaaagattaatggaaaggattgcacttctagagaaa atcaaaagcagtgtggatgaaaagcatgccaggctgtaccagatggtgaaggaagggaag aaattgctgtctgctgtgaactgtccagaaataagaagccagattgggaagctggaagag cagtggttgtctttaaccaaaaaagttggccatgagctacaccgacttcaaacattactg aaactcctggtcagctacaacagagactcagaggaattgatgaaatggttggattctgct cagcagagaatgaatttttggaaggagcagtctctcaatgtgtcacaagatcttgccacc atcagggacagcatcagcagtttgtttacattttctaaggaagttgatgaaaaatcttcc ctgaagtcatcagtggtgagcactgccagccagctcctccacgtgaagcaagctgatact gcaacacttaggtcattcttggcaaagtttgagcaaaaatggggagaactgattacacag ctcccagccatccaagaaaagcttcaccagcttcagatggaaaagctttcatcacgggaa gctattgctgaactaatggcctggctggaccatgtggaacagcagcaggaacgtgaggag ccagtaaattcacaacacagtgctgcccaggtcaagaccctccttcagaagtacaaggaa tacatgatggaaatgaactttaagcagtggatggtagattttgttaaccagtccctgctg cagatgagcacctgtgacgtggagagcaagcgctacgaaaggacagagtttgctgagtgc ctgggtgagatgaacctgcggtggcaccggctgcaggcatccctcaacagaaagatacaa gacctggaacacattttggaggatattactgagaatgagaacaaagcccagactctgcac agctggctggaagctcagagtgatcgactgagatccttacagaccccagcaagtctgatc tctgcacagaacaccttagatgattgcaaggagttggaaaatcaactcgtggctaaatcc aaaactcttgatgagctcaaagagagtttggtttcggatggtagtgcagaagaaacccca gaagctcagtctctgaggatagctgagctgtgtgaaatgaaggacagcattgtaaaccag gttgcacagctgaaggcctcaatggagtcaatactggagcagtggagagcatatgatgaa atttatgcagaagtcagcttgatgacaacaagatatttgtactgcatagaccagtgcaaa ccttctgaggaagaagcttcattggaagctttgaaaaaacaggtcaaaactctccaggct cttcaagatgaatcagagaacagtgaagaaagctgggccaagctccaggctgctgccagt accctgaagaagagctgctccccctcctttgcagagattattgaccagaaatgcatggag gcacacactaggtggaactcagtaaatgaagacatcacagatcagctgagggcagcacag gcagctctgcagctctgggagccctttgatgctctgtgctctgagacagcagccaagtta cagcagtacagccagcagtgtgctcagctcttggatgctcacatgcctgaggagaactcc atagaaaccctggagcagaggatacaggagataaagaatttacagcacggccttcaaaac cttgcaggatgccgaacccagatttatttgcaggctgacaggataaaacagcaggctggg acagctgctgaggccactctgatggagaagctgcagccattgcagagagcaacctatttg gaaaagatgttgcagaggaagttggatgaacttcagttcaatcttttacaactggaggat ttcaacaactgcctggaaacactggagggtcgtgtcaagaattgcacagacacctttgat agcctctgtctagaggaaggagacaactcagaattgctcctgaagcagacactggagctt gctgcactttctccaagcatagagagtttgaatgaagcaagcataaagctgccactcagt gacttcagcctgaagaaaatgcagagcctgactcggcagtggagtcagaaaacagcagct gctctggaatgttgcagtatgcttgagggaacccaaaatgatgagaagaaattctttcag aaatgtgaaaagtggatgaaattcctagaaaaaatgaaagaagccttaaaaacagatatt ccaggacggtttgaggaactgcaagagcaacagagagtatatgagatgctgcagactgag atttccataaatcagcagacatttaattctatcatagaaaaagttctactctccttggaa tccggagaagcagagaaaaggacagagtttatttccaagctgacactgctgaaagagcag tggcagaatgttatccggatggttcagcagaggaagaaagacatcgatgcactcgtgagc cagtggcagctcttcaggagttccctgcagagcctcagcagattccttgatgacacaaac agcttccttgcagctgtgaagagccaggactgttacagcctttaccagcttagaaatgta attcatgatttcaagagtaaggcagtgatccttcagaggtggcaagccatgtacaccctg gtcatcgacgtgggggagaagctgcgcgctgtctctgatcccagcaccagcgctgctctc caggaggagctcagccacttacagcagcgctgggggaaaacccaggccctgctggagaag aagaagatgcagttcagtggcaccctacagacttgtgaccgctttgaaaagcaaaccaag gaactggaaagcagactgcaagagctaaaggagaaagtaaaagatccactccctgttgag catgaagagctccacaaagccaaggaacatattaaggagctggagcagtcgctggcagac tgggcccacgacatgaaggagctgcaggccatgaaggtggagctggcacacctcatcctc accgaggacatgatggtgctcaaggagcaagtggagcatttgcacaggcagtgggaagag ctctgcttgcgggtgtccctgcggaagcaggagattgaggacaggctcaatgcctggatt gtgttcaatgagaagaataaggagctgtgctcctggctggtccaaatggaaagcaaagtg ttgcagactgcagatgttagcattgaagacatgatagacaaattgcagaaggactgcatg gaagaaataaccctgttcagtgaaaataagcttcacttgaaacaaatgggtgatcagcta atcaaggctagcaacaagagccgagttgcagaagtagatgataaactcaacaaaatcaat gatcgctggcagcacctcttcgatgtcattggagcacgggtgaagaaactgaaggaaaca tttgcttttatacaactattggacaaaaacatgagtaaccttcgcacctggttggcccgg attgagtctgagctttccaagcctgttgtttatgacatctgtgatgaccaagaaatccag aagagactggcagaacagcaggacctgcagagagacatagagcagcacacggcgggcgtg gagtccgtgttccagatctgtgaagtcctgctgcacgactccgatgcgtgtgctaatgag acagagtgtgactccatccagcaaaccaccaggagcttggacagacggtggagaaacatc tgtgccatgtccatggaaaggcgaatgaaaatcgaggagacctggcgtctgtggcagagg tttttggatgactattctcgctttgaagattggctaaaagcgtctgaaaatatagcagct aggcctaactcttcagaggtcttgtacacacatgcaaaagaggagctgaaaaaatttgag gcgttccagcggcagatccacgagcgcctgacgcagctggagctgatcaataagcagtac cggcgcctggcccgcgagaaccgcaccgactcggccagcaagctcaaacagatggtgcac gagggcaaccagcgctgggataacctccagaaacgagtggcttccattctcaggaggctc aagcacttcaccaatcggagagatgagtttgagggaacaagggaaagcatccttgtctgg ctcacagaaatggacctacagctgacaaacgtggaacacttctcaaaaagtaactttgat gacaaaatgcgccagttaaatggtttccaacaggaaataacattaaacaccaataagatt gatcagctaattgtttttggagagcagttgattcagaagagcgagcctttggatgccatc ctgattgaggatgagttggaagagcttcatcgatactgccaggaggtgtttgggcgagtt gcccgcttccatcaaagactgacttcaagggaccctggattggacgatgaaaaagacaac tctgaaaatgagacagatcaagaagactccagagaaatccagaatgatccctggcataag aaagccatcactgaggggccctcatcaacacagtccctttgccaccttatgcccccgacc cagggccatgagagatcaggctgcgagacccctgtcagcgttgactccatcccacttgag tgggatcacacaggtgatgtgggaggttcttcctctcatgaagatgatgaagaagcaaca tattacagtgctctgtcagatgtagaaatcactgaaaaccctgaggcatatcttaaaatg accacaaaaactttgaaagcatcttctggaaagtccgtttcagaagctcgtccttggcat tctccaggtagcccagtctgcaggaaacacagatacaaccaggcagagatggttggaaat gtgttgtctggaccagagacaagtactccctttaaaccagcctatgtgaagcagctcagc tctgcaagcagcagcagcagcaaggagaagattccatctgccaacatgagtgatgaggag ccccaagatgaccaagaacttgtgaatctagcagcaacagagaagcagtcaggcattatt gataggtgggagctcatccaagctcaagacctcagaaataaacttaggatgaaacagaaa ttgcagcagtggcagcagctggactcagacctcagtgatatctctgcttggcttgataaa actgagcaagagctggaagagctgcaaaaggtgaagcttccaaccagcatgcaggcattg gaacaaaaggtcaagaaattgaaagacatgcttaaagcatttgacagctacaaagcagtg ttgctttctgccaacctgagcagcaaagaattccagaaagcagacagcacagagttcaag gagctgcagaacaggcttcggaaggtcaacttgcactgggagaaggcaaatcgtgcactg gacaactggaggaagggtttgcagcaagccttactgcagtgccaggatttccaggaccag agccaaaagctaatcctgtggttagcaagtgctgaaagccggaggaatgaagcacaaatc acagatcccaatgctgatctcaatacaatactggaatgccagaaggagctgatgcaactg gagaaagagctgctggagcaacagcttaatgtgaactccctccaagagctcactgcttac ctgctgctgaaatcagatggtgattacattgaagaggaggagaaggtccatgtaattgga acaaaactgaaacagctgattgaacaagtctctcatgacttaaaaacaatacaagggaat ctggacaccaaaacattcctgctagttccagatgacttggactcaggagtctataatcca gaagaagagaaatccagccctgctgtgaagaagatggccctcaggagagcagctgacagc agaaatggcagcagcacaaggagtgaaagccattcagaacctgtgcagacagcccctcgg tctccctctttcttctaccgagtgttgagagcagctttacctctgcagttgttcttcctg ctgcttttgctcctggcttgcatgatcccctcctctgaggaagactacagctgcacccag gccaacaacttcgcccgctccttctaccccatgctgcgctacaccaacgggccccccccc acctag

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