Streptomyces castrisilvae: P8A18_25145
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Entry
P8A18_25145 CDS
T10534
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
scat Streptomyces castrisilvae
Pathway
scat00470
D-Amino acid metabolism
scat00550
Peptidoglycan biosynthesis
scat01100
Metabolic pathways
scat01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
scat00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
P8A18_25145
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
P8A18_25145
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
P8A18_25145
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
scat01011
]
P8A18_25145
Enzymes [BR:
scat01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
P8A18_25145
Peptidoglycan biosynthesis and degradation proteins [BR:
scat01011
]
Precursor biosynthesis
Amino acid ligase
P8A18_25145
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
ATP-grasp_3
Motif
Other DBs
NCBI-ProteinID:
WLQ36508
UniProt:
A0ABY9HR74
LinkDB
All DBs
Position
5752841..5753998
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AA seq
385 aa
AA seq
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MSSENLPQSTEHQLRKPRVAVVFGGRSSEHGISVVTAGAVLNAIDRTKYDVLPIGITTDG
RWALTADEPERMAIADRKMPDVAQLAESDEGGVVLSVDPGSREVVYSEPGSVPKALGEVD
VVFPVLHGPYGEDGTLQGLLELSGVPYVGAGVLASAVGQDKEYMKRVFTSFGLPVGPYVV
VRPREWDNDPAGARERITEFAAEHGWPLFIKPARAGSSIGITKVEDVSQLDEAIEEARRH
DPKFLVESLLRGREIECGVLEFEDGPRASVPAEIPPVTSHDFYDFEAKYIDSASGIVPAP
LTGEQTAEVQRLAVEAFEAASCEGLVRADFFLTEDGGFVINEINTLPGFTPISMYPRMWQ
ESGVSYQQLVDRLIQAALDRPTGLR
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
atgagcagcgagaacctcccccagagcacggagcaccagctccgcaagccgcgtgtggcc
gtcgtgttcggcggccgcagctccgaacacggcatttcggtggtcacggccggtgccgtc
ctgaacgccatcgaccggaccaagtacgacgtcctgccgatcggcatcacgacggacggc
cgctgggcgctcaccgccgacgaacccgaacgcatggcgatcgcggaccggaagatgccc
gacgtggcgcagctggccgagtccgacgagggcggcgtcgtgctctccgtcgaccccggc
agccgcgaagtggtctacagcgagcccggctcggtccccaaggcgctcggcgaggtcgac
gtcgtcttccccgtcctgcacggcccctacggtgaggacggcaccctccagggcctcctg
gaactgtccggcgtgccgtacgtgggcgcgggcgtcctcgcctcggccgtcggccaggac
aaggagtacatgaagcgcgtcttcacctccttcggcctgcccgtcggcccgtacgtggtc
gtgcgcccccgcgagtgggacaacgacccggccggcgcccgcgagcgcatcacggagttc
gccgccgagcacggctggccgctcttcatcaagcccgcccgcgccggctcgtccatcggc
atcaccaaggtcgaggacgtctcccagctggacgaggcgatcgaggaggcccgccgtcac
gaccccaagttcctcgtggagtcactgctgcggggccgtgagatcgagtgcggcgtcctg
gagttcgaggacgggccgcgcgccagcgtgccggccgagatcccgcccgtcacctcgcac
gacttctacgacttcgaggccaagtacatcgactcggcgtccgggatcgtgcccgcgccg
ctcaccggcgagcagaccgccgaggtccagcggctcgcggtcgaggccttcgaggccgcg
tcctgcgagggcctggtgcgcgccgacttcttcctcaccgaggacggcggcttcgtcatc
aacgagatcaacaccctgccgggtttcaccccgatctcgatgtacccgcgcatgtggcag
gagagcggcgtcagctaccagcagctggtggaccggctcatccaggcggcactggaccgg
ccgaccggactgcgctga
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