KEGG   Scyliorhinus canicula (smaller spotted catshark): 119953931
Entry
119953931         CDS       T11175                                 
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
scau  Scyliorhinus canicula (smaller spotted catshark)
Pathway
scau04010  MAPK signaling pathway
scau04012  ErbB signaling pathway
scau04020  Calcium signaling pathway
scau04510  Focal adhesion
scau04520  Adherens junction
scau04530  Tight junction
Brite
KEGG Orthology (KO) [BR:scau00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119953931 (erbb2)
   04012 ErbB signaling pathway
    119953931 (erbb2)
   04020 Calcium signaling pathway
    119953931 (erbb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    119953931 (erbb2)
   04520 Adherens junction
    119953931 (erbb2)
   04530 Tight junction
    119953931 (erbb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:scau01001]
    119953931 (erbb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:scau04147]
    119953931 (erbb2)
   04090 CD molecules [BR:scau04090]
    119953931 (erbb2)
Enzymes [BR:scau01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     119953931 (erbb2)
Protein kinases [BR:scau01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   119953931 (erbb2)
Exosome [BR:scau04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   119953931 (erbb2)
CD molecules [BR:scau04090]
 Proteins
  119953931 (erbb2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 Haspin_kinase RIFIN ABC1 LAX Adeno_E3_CR2 MpPF26 Stevor bCoV_NS7B BREX_BrxC_helical Syndecan
Other DBs
NCBI-GeneID: 119953931
NCBI-ProteinID: XP_038634544
LinkDB
Position
19:1446229..1526182
AA seq 1235 aa
MRLAGLLLLTALGSARRTVCPGTDMKPDLSFSLENHYYTLRKQYENCHEVQGNLEITHLT
GNRSLSFLQNIQEVQGYVLIAHNEVEYIPLENLRIIRGSQLYEDQFALAVLSNFNPGGTG
LRELRMRSLTEILIGNVQISNNPWLCYQETIQWDDIQDKKNRIPFAGPLDTNRTVQCGNC
SSACKSRSCWGSGPEYCQILTRTVCATECLTRCKGPDPTDCCHSQCAAGCTGPKDTDCLA
CYHFSNAGTCRGDCPPLNTYNAHTYQMEPNPEGTYIFGASCVKKCPRNYLANNVGSCTLN
CPNDTREVNRGDEQKCEKCNGPCPKVCNGLGVNSLKGVRAVNSNNIDSFAGCTKIFGSLV
FVAETFFGDPVAKTPPLDPRKLQVFGPLTEITGYLYIEAWPRNFTDLNIFENLVVIRGRV
LSRGTYALLVQNLQIQSLGFRSLKEISNGLVLIHQNPNLCYASSIPWIRLFKEERQEALI
TANKPQDMCEAEGSICYSLCTNNTCWGPGPTNCLSCEKFFRGRECVESCNLYEGVVREYL
QELSCIQCHKECLPQNKNLSCSGMGADDCVECVNYKDGADCVEKCPSGSHGHVWKFADEN
ALCQLCPTNCSHSCTTDDRGCPVEPIHSQVTSVVAGIVGVLLFLVLVILLIVWFKRKKRL
KRKHTMLRLLEQRELVEPLTPSGVVPNQAQIRILKETEMKKVKILGSGAFGTVYKGVWMP
EDEDVKIPVAIKVLREGTSPKANKEILDEAYIMAGVSSPYVCRLLGICLTSTVQLVTQLM
PYGSLLDYIRENKDRIGSQHLLNWCVQIAKGMNYLEDHVRLVHRDLAARNVLVKSSNHVK
ITDFGLARLLDIDETEYHADGGKVPIKWMALESILHRKFTHQSDVWSYGVTVWELMTFGA
KPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVTEFTKMA
RDPPRYVVIQGDEQMVLQSPTDSKFYRTLLEDEDMQDLIDAEEYLVPHQGFFNTQPCTHY
SSRMSSSRSATSVAEVEGQGSEAAQSPSLVYGATQQSAAACVDTYADAEDSGCRGVTCCP
SGEDSVTQRYSSDPTVRVTGEEEDEVDSYISLGSDQTETDYVNQPEETSSPAQAGRPELV
ARSSTGNGPLIPKCSFRNMVENPEYLTHQSLVSGVKDLPFDNPDSWSQDPQGSSQPGKTL
CLTPATPRLTQPNGYIRVATAENPEYLGLAETSSV
NT seq 3708 nt   +upstreamnt  +downstreamnt
atgcggctcgcggggctgctgctcctcacggcgctcggctcggcccggcggacagtttgt
cctgggacagacatgaaaccggatctgtcattcagtttagagaaccattactacacgttg
cgcaaacagtacgagaactgccacgaagtgcagggcaacctggagatcacccacctgaca
gggaaccgcagcctatccttcctgcagaatattcaggaggttcaaggttatgttttaata
gcgcacaatgaagtagaatacattcctctagaaaatctacgcatcataagaggaagccag
ttgtacgaggatcagtttgcactggctgtcctgtctaactttaaccccggtggtactggt
ctccgagagctgcgcatgagaagtctgacagaaatcctgattgggaatgttcagatcagc
aataacccctggctctgttatcaagagacgatccaatgggatgatattcaggacaagaaa
aacaggatccctttcgcaggaccgctggacacgaaccgaaccgtgcagtgtggtaactgc
agctctgcctgtaaatcaagatcgtgttggggctcaggtcctgaatattgccagatatta
actcggacggtctgtgccaccgaatgtctgactcggtgtaaaggaccagacccgaccgat
tgttgccacagccagtgtgctgcaggctgcactggacccaaggacactgactgcctggcc
tgttaccatttcagcaacgccggtacgtgtcgtggagactgtccaccactcaacacatac
aatgctcacacctatcagatggagcccaatcccgaaggaacatacatctttggagccagc
tgtgtcaaaaagtgtcctcgcaactacttagcgaataatgttggttcgtgcactctgaac
tgcccaaacgacaccagggaagtgaacaggggggatgaacagaaatgcgagaagtgcaat
ggcccctgccccaaagtgtgtaatggtttgggtgtaaacagtctgaagggtgtgcgggcc
gtgaactcgaacaacatcgattccttcgctggttgcaccaagatcttcggaagcttggtg
tttgttgctgagactttttttggtgacccagttgcgaagaccccacccctggatccaagg
aagctgcaggtttttggtcctttgacagagatcactggctatttatatattgaagcctgg
ccacggaattttactgatctaaatatatttgagaatcttgttgtcatccgaggacgagta
ttgtccagaggtacttatgcattgttagtgcagaatctccagatacaatctctgggattt
cggtctttgaaagaaattagtaatgggctggtgcttattcaccaaaaccctaacctctgc
tacgccagctctattccctggattcgtttgtttaaggaggagcgtcaggaggcgttgata
acggctaacaaaccacaggacatgtgtgaagctgaaggaagtatctgctacagtctgtgc
acaaacaacacctgttggggcccaggaccaacaaactgcctctcttgtgagaagttcttc
cgaggccgagagtgcgtggaatcatgcaacttatatgagggggtggtgagagagtacctg
caggagctgtcttgtattcagtgtcacaaggaatgtctcccacaaaacaaaaacctgagc
tgcagcggaatgggagctgatgactgtgtggagtgtgttaattacaaggatggtgcggat
tgcgtggagaaatgtccaagtgggtcacacgggcatgtctggaaatttgccgatgaaaat
gccctctgtcaactgtgtccaacaaactgcagtcattcatgtacaactgatgaccgtgga
tgtcctgtggagcctattcacagccaggtgacctcagtggtggccggaatagtgggggtg
ctactcttcctggtccttgtgatactcctcattgtctggtttaagcgcaagaaacgactg
aagcggaaacatacaatgctgagactcctcgagcagagagagctggttgaacccctgact
ccaagtggagttgttccaaaccaggcacagatccgaatcctgaaggagacggaaatgaag
aaagtgaagattcttggatctggtgccttcggaacggtttacaagggcgtctggatgcct
gaggacgaagatgtgaagatccctgtggctattaaggttttaagagagggaacttctcca
aaagcaaacaaagagatcctggacgaagcatacataatggcaggagtgagtagtccttac
gtctgtcgtctgcttggcatctgcctgacatccactgtgcagctggtaacacagctgatg
ccatacggatctctgctcgattacatccgagaaaacaaggaccggattggatcccagcat
ctcctcaactggtgtgtgcaaatcgcaaagggaatgaattacctggaagatcatgtgcga
ttggtccaccgcgatctagcagcaagaaacgtccttgtaaaaagctcaaatcacgtgaag
atcacagactttggacttgccagactcctggatatcgatgagacggaatatcacgcagac
ggaggaaaggttccaataaaatggatggcattggaatccattttacaccgaaaattcact
caccaaagtgatgtgtggagttacggtgtaacagtctgggagttgatgacatttggagct
aaaccatacgatggaatccctgctcgagagatccctgacctgttggagaagggggagcgt
ctcccacagcccccaatctgcactatcgatgtctacatgatcatggttaaatgctggatg
atcgattctgaatgtcgacccaggttccgagaattggtgacagagttcacaaaaatggcc
cgagatccgccgagatatgtagtaatccagggggatgagcagatggtccttcagagcccc
actgacagtaagttctaccgcaccttgctggaagatgaggatatgcaggacctgatcgac
gctgaagaatatctggtaccacatcaggggtttttcaacactcagccctgcacccattac
agcagcagaatgtcatcttccagaagtgcaacaagtgtggcagaggtggaaggtcagggc
tctgaggctgcacagagccccagcctggtatatggtgccactcaacaatcagcagctgcc
tgtgtggatacttacgctgatgccgaggattcaggatgtagaggagtgacatgctgcccc
agtggagaggacagtgtcacacagcgatacagctctgaccccacagtacgtgtgactggt
gaggaagaggatgaggtggacagttatatctcactgggatccgatcaaacagaaaccgat
tacgtaaaccaaccagaggaaacctcatcccctgcccaagctggaaggcccgagttagtc
gctcgtagcagtactgggaatggccccctgatccccaagtgttcattcagaaacatggtg
gaaaatcccgaatacctgactcaccagagtctggtatccggggtcaaggatctgccgttc
gataatcctgattcctggagccaggatccccagggcagctcccaacctgggaaaactctg
tgcttaacccctgccactcccaggctaacacaacctaatgggtacatccgagtggcgacg
gcagagaatccggaatatcttggcctggccgagaccagcagtgtgtag

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