Scyliorhinus canicula (smaller spotted catshark): 119973786
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Entry
119973786 CDS
T11175
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
scau Scyliorhinus canicula (smaller spotted catshark)
Brite
KEGG Orthology (KO) [BR:
scau00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
scau01001
]
119973786 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
scau04131
]
119973786 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
scau04147
]
119973786 (lrrk2)
Enzymes [BR:
scau01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
119973786 (lrrk2)
Protein kinases [BR:
scau01001
]
Serine/threonine kinases: TKL group
LRRK family
119973786 (lrrk2)
Membrane trafficking [BR:
scau04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
119973786 (lrrk2)
Exosome [BR:
scau04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
119973786 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
Roc
COR
LRR_4
Ras
LRR_1
LRR_14
LRR_13
Arf
Beta-prop_EML_2
GTP_EFTU
WD40_2
WDR55
Ank_2
LRR_9
WD40_CDC20-Fz
LRR_NXF1-5
Beta-prop_RSE1_2nd
LRR_6
G-alpha
Arm
MMR_HSR1
Beta-prop_HPS5
LRR_LRWD1
Motif
Other DBs
NCBI-GeneID:
119973786
NCBI-ProteinID:
XP_038668138
LinkDB
All DBs
Position
11:121779563..121964294
Genome browser
AA seq
2524 aa
AA seq
DB search
MAGSEQREETLKKLIVRLQNVEQGKEVKALLQILDDLTLLTTVQNASTLFGNKNVHMPLL
LILESFTDVPIQQAGWLLLCKLMELCPEIINKLATPQDMGKDWDVLGVHQQILNLLKSYN
FNSTILLIGLKVLTLLVHSDEISLLLRDEDMDVFSLVLDGMKSFADHCEVQIHGCQVLYA
LLEKVPDEQVIEFVEGKDHWVILKAIKNFHEHEGMALHGLRALFPLAGPQNNVEILMSGN
EKCYSLVTGAMKRFPDNETIHEIGCCLLQRFTLDSFYYILLLNGAHKVVINAVLRYPQNG
TVQAAALSTLALLTETIFVNKGLEEGKDDLSWTEACCRALDSFKENAKVQEAACWALYNL
LLHQNDLHAKFGDEDACYPVHRMMMAAMLLHSNSKEVFRAAANALATWQTKAQLILFLYV
FNFLLFNSTSKKASVGKRDTYEHSRPNEKNTQTLVMSWKVLASSLIKLFLGSTLSLDIMR
LTSRRIVDTLKISLHNSSVQLEALRVMAHIICPVTLKEDMVDAEQDTNELESMQKTIKKQ
CLPDGFHGLILDAMNKFIAHPAIQHCGLRLLCSITDHSGVPEMMRRGALVTVIHTLQMHP
HKREIQYLCLKLLGILVPKKDLCPSLLGLVAKILVEALRRYEEDVEVQMQGIQAALTYFK
TIPSSCEIFFKEDIDRYIFQQVTDCRSKQLQRLLFKCLSKLTIDRGITNQMLENACSENN
VMMAEYLITLEADVNYKSKNESLIYQACKQSNNPLLVELLLNSGAREQDIRKALDASIKM
GDGKIISVLLRKLGLDQNNKAICLGGLHMGKIEAAWLLPLFPDERFPISKRQLSGSLAQL
LRKDGTGSALSQMQSSRTNSELSFSEEALDKSNDYTALSDVSTDTEESSLFDDLESEDTK
YYHQVRRSYVVVQNPNYLCTGMHSESTVNLCHSSSLSSLDDVEPAVNPRRRLISHVFLKP
DCASKRPSFGNGQNQLQLASETEFIWSLDLSANDLENLSSISEKCCIAAQLAQVQKLDLS
QNNLTDVSQDLCTILECLTDLDISNNKFTSFPSCLLEMQSITSLDISRNNIGHSLTTNGK
CPTLKKLNLSHNQLSSFPECLNKTTEKLQELLIKGNKMRTIVSLLCLTELNLLDLSQNCI
STIVDTFLIQCSKLETFRVSENHLSMLTGLPSKMTTIDLASNKFDTVPKAILKLQHLRSV
NLSHNKISELPGPAHWESSSLRELIFNHNQISVLDLSEGANKWSRLEKLNLSNNKLKELP
PQIGQLENLTSLILSYNSDLRSLPNEMGKLQKLWELELQGLFLDLDLKHVGSKTKDIIRF
LHQRLKKAVPYYRMKLMIVGNASSGKTTLLQQLMKCKQPNPGPEKATIGIDVKEWPVNGK
EKKGKKNQYMLSVWDFAGQEEFYSTHPHFMSTRALYLVVYDLSKGVGEIDAIKHWLFNIK
ARASSCPVILVGTHVDMTNEKHQQNCITKIKMEFLQQHNFPPVRDYHFVVATEESDSLVK
LRRAIINEIQTFKIRDQPVMGQLIPHSYMELEKRIIQERKTVLTAFPVIHQQRLLEIVQE
HHLQLDENELPHAVHFLNESGVLLHFHDPALHLRGLYFIDPQWLCKTMAQIVTVKAASFP
KHPCGIIYRSDVEKLLAQKNSFPQNYMSQYIKLLEKFQIALPLGEEQLLIPSSLPDQRPV
IELPHCENSELIVRLYEMPYFPMGFWSRLINRLLEVSAYMLRRQGGEKPLRPNRTYWRQG
VYLIWSPEAYCLVDSAVLDNKPQSILKITVPCCRKGFILLGQIVDHIDSLLEEWFPGLLE
TDISGEGGTLLKKYALYSFEDDQECQQILLDDLLDIAEEGDFLTCPTDRSNKISISQVAP
DLVLVDLPRNIMLDINHLKLEQTPDFLLGDGGFASVYRATYKCREVAVKIFNKHVSQMHL
HRLLRQELAVLSYLHHPSLVSLLAADFRPRMLVMELAPKGSLDLLLNLEKDHLNRTLQHR
IALHVADGLRYLHSSMIIYRDMKPHNVLMFSLNPNSAIIAKIADYGIAQYCCRMGIKSSE
GTPGFRAPEVAKGNVIYNHQADVYSFGLLLYDLITNGERISIGMKFPNDFDEMAVQGKLP
DPVKEFNCSPWPGIQTLIDDCLKQNPDDRPTASQVYDTLNSVELLCLKRRMIVPSNLTAD
CMVATNSICRKPRVWIGSGKRDKAQLSCLELDSDVPAVVNIEDNRILCLALVCVIGEEVN
WVVAGTQSGHLWIVNTENVKSVHQLRKMSDSITCLFCTHHSKHSNEEHFLFVGTADGKLA
IFKDTTVKYEDGAPLKVVDIGDISTPLVCLSVSSTSEQVVFWASCGTKIVSLSSDFAVQK
VIDTKTRSLKHQKYYSDGNIITMIIDKYIYLAKKDSHVVELWDKKSYKISASIDCASILK
NDTYSARVKALHLQKATCLWIGTGGGDVLLLDLSTHQPILVIDKCCHSIRSMVTAQIEKG
HLRTVMLILGNFYKDYDENNKQQSGLQSQLFVWDMNLPYEIQNLKKHTDMRREIIEKMRT
GSLE
NT seq
7575 nt
NT seq
+upstream
nt +downstream
nt
atggcgggctcggagcaacgggaagaaacgctgaaaaagctcatcgtccgcctccagaac
gtcgagcaggggaaagaggtcaaagctttgcttcagattttggacgacttgactctcctc
accaccgttcagaatgcctcgactttattcggaaataagaacgtccacatgccgttgctg
ttgattctggaatcgtttaccgatgtccccatccagcaggcaggttggcttttactctgt
aaactgatggagctgtgtccagagataattaacaaattggctacgccccaagatatggga
aaggattgggatgttctcggagtgcatcaacagatcctgaatttgttgaaatcttacaat
tttaactctaccatactgctgattggccttaaggtgttaacactccttgttcattcagat
gaaatttcattattgcttcgagatgaagatatggatgtgttttctttggtccttgatgga
atgaaatcatttgctgaccactgtgaagttcagatacatggatgtcaagtgttgtacgca
cttttagaaaaagttccagatgagcaggtgattgaatttgtagaagggaaagatcactgg
gtcattttaaaagccataaaaaactttcatgaacatgaaggtatggcactccatggcctg
agagctctgtttcctttagctggtccacaaaataatgtagaaattctgatgtctggaaat
gaaaaatgttacagtctggtaactggtgcaatgaaaagatttcctgacaacgagacaatt
catgaaattggttgctgtttactacagaggtttacacttgatagcttttactatattttg
ttactgaatggagcgcacaaggttgtcatcaatgcagttctaagatatccacagaatggt
acagtgcaggctgcagccctcagcactttggctcttttaactgaaacaatatttgtgaac
aagggtcttgaagaaggaaaagatgacctcagctggacagaggcctgctgtcgagctttg
gattcattcaaggagaatgcaaaagtccaggaagcagcttgttgggcactgtacaatcta
cttttgcatcagaatgatcttcatgcaaagtttggagacgaagatgcgtgctacccagtt
cacagaatgatgatggcagccatgttattacattccaattcaaaagaagtgtttcgagca
gcagccaatgcgctggcgacttggcagaccaaagcgcaactaattttgtttctttatgtg
tttaattttcttttgtttaacagcacaagtaagaaagcttctgttggcaaaagggataca
tatgaacattctagacctaatgaaaaaaacactcagactcttgtgatgtcctggaaagtg
cttgcaagttccttaataaagctatttctgggaagtactctgagtctggatattatgaga
ttaacttcaaggagaatagtggacacattgaagatcagtttgcataattcttcagtacag
cttgaggcccttcgggttatggcacatattatttgccctgttactctgaaagaggacatg
gtggatgcagagcaagatacgaacgagttggaatcaatgcagaaaacaattaaaaaacag
tgtttgccagatgggtttcatggattgattctcgatgctatgaataagttcattgcgcat
ccagctatccaacattgtggccttcgattactttgctccatcactgatcattcaggtgta
ccagaaatgatgagaagaggggctttagtcactgtgatccatactttgcaaatgcatcct
cataaacgagaaattcagtacctgtgtttgaaacttctggggattcttgttccgaagaaa
gatttatgtccttccctcttgggtttggtggcaaagattttggtggaagcattacggaga
tatgaagaggatgtagaagtgcaaatgcagggtatccaagcagctttgacgtatttcaaa
accataccgtcttcttgtgaaattttcttcaaggaagatattgatagatatatttttcag
caggtgacagattgcagaagcaaacagctacaaagactcctcttcaaatgcttgtctaag
ttgaccattgatcgtggaataacaaatcagatgcttgagaatgcttgctcagaaaacaat
gtcatgatggcagaatatttaatcaccttggaggctgatgtcaattacaagtctaaaaat
gaatcactgatttatcaggcttgtaagcaaagcaacaacccattgttagtggagcttttg
ctcaacagtggagcacgtgagcaagatattcggaaagcattagacgccagcattaagatg
ggtgatggtaaaatcataagcgtgcttttacgaaaacttggactggaccaaaacaataag
gccatttgcctgggtggacttcatatgggcaagattgaagctgcttggctacttccattg
tttcctgatgaaaggtttcccatttcaaaacgacaattgagtggctccttggcacaactt
ttgcgaaaggatgggacaggatcagcactatcacaaatgcaaagttcaaggacaaattca
gaattgagcttctctgaggaagcattggacaagagcaatgattacactgcgttatcagat
gtgtcaactgatacagaagaaagcagcctattcgatgacttggaaagtgaagacacaaag
tattatcatcaagtcaggaggagttatgttgtagttcaaaatccaaactacctgtgtact
ggaatgcacagtgagtctacagttaatttgtgtcacagcagctctctgagttcacttgat
gatgttgagcctgcagttaacccaaggcggagacttatttctcatgtgtttcttaaacca
gattgtgcgtcaaaaagaccctcttttggaaatgggcaaaaccagttgcagcttgcttct
gagacagaattcatctggtcattggatctttctgcaaatgacttagaaaatctaagctcc
atcagtgaaaagtgttgtattgctgcacaacttgcacaagtacaaaagctggatctaagt
caaaataatttaactgacgtctcccaagatttgtgcactattcttgagtgcctgactgac
ttggacattagcaataacaagttcacctcctttccttcatgtttgctggaaatgcagtcc
attacctcccttgatatctccagaaacaacatcggccattctctgactacgaacggcaaa
tgcccaacactgaaaaaattaaatttgtcgcataatcaactctcctcttttccagagtgt
cttaataaaactacagaaaaattgcaagagctgttaattaaaggaaacaaaatgaggaca
attgtatctttgctatgtttgactgagcttaatctgttggatcttagtcagaattgcatt
tctaccatagtggatacatttctgatccagtgctcaaagctggaaacattcagagtctcg
gagaatcatctcagtatgttgactggtttgccgtcaaaaatgactacaatcgatttggcc
agcaacaagtttgacacagttcccaaagcaattctcaagcttcaacatttaaggagtgtg
aacctaagtcacaataaaatatcagagctccctggacctgcacattgggagtcgtcaagt
ttaagggaactgatattcaaccataaccaaatcagtgttttggatttgagtgaaggagca
aacaaatggtcaagactagaaaagctgaatcttagcaataacaaattgaaggagctacct
cctcaaattggccagctagaaaacctaacatctttaatcctgagttataactccgacttg
aggtccttgccaaatgaaatggggaagctgcaaaagttgtgggagcttgaactccaaggg
ctgtttctggatttggatttaaaacatgtcggcagcaaaacaaaagatattataagattt
ctacatcagcgcttgaagaaagctgtgccttattacagaatgaagttaatgatagtggga
aatgctagtagtggtaaaacaacattgcttcaacaactgatgaaatgcaagcaaccaaat
ccagggccagagaaagccactattggaattgatgttaaagaatggccagttaatggaaaa
gagaaaaaagggaagaaaaatcaatacatgttgagtgtctgggattttgcaggacaagaa
gagttctacagtacgcacccccattttatgtcgacacgagccctgtaccttgttgtttat
gacctcagtaaaggagttggtgagattgacgctatcaaacattggctgttcaacatcaag
gcacgtgcctcatcctgtcctgtaattcttgttggcactcatgttgacatgaccaatgaa
aaacatcagcaaaactgcataaccaaaattaagatggaattccttcagcaacacaatttt
cctcctgtccgtgattaccattttgtggtggccacagaagaatctgactcccttgtaaaa
ctacgtcgagccattattaatgaaatacagactttcaagatcagagaccagccagtaatg
ggtcagctcatacctcacagttatatggaattggaaaagaggattatacaggaaaggaag
actgttctgacagcattcccagtaattcatcagcagcggcttctggaaatagttcaagag
catcatttgcagttggatgaaaatgagctgccccatgctgttcacttcctcaatgagtct
ggtgtgctactgcactttcatgatccagctcttcaccttcggggtctttattttatagat
ccacaatggctttgtaagacgatggcgcagattgtgactgtcaaagcagcaagttttcca
aaacatccttgtggaattatttaccgatcagatgttgagaagcttctcgcccagaaaaat
agcttccctcagaattacatgtcacagtacataaaactcctggaaaaattccaaattgca
ttgcctttaggagaggaacaactacttattccaagcagcttacctgaccagagacctgta
attgaactcccacattgtgaaaactctgaattgatagtaaggctttatgagatgccatat
tttccaatgggattctggtccagacttatcaacaggttactggaggtttctgcttatatg
cttcgtagacaaggtggagagaaacctttacgtcctaataggacatattggagacaagga
gtctatctaatctggtcaccagaagcctactgcttggttgactcagctgtgctagacaat
aaaccacagagtattctcaaaataactgttccatgctgcaggaaaggattcattttgctg
ggccagattgtagatcacattgactctctgttggaagagtggtttccagggttattggag
acggacataagtggtgaaggaggcactcttttgaagaaatatgctttgtatagctttgaa
gacgatcaagaatgtcagcagattctactagacgacttgctagatattgctgaagaaggt
gattttttgacttgtcccactgatagaagcaacaagatttccatttcacaagttgcgcca
gaccttgtgctagttgatttacccaggaacattatgctggatattaaccatcttaagctt
gaacaaacgcctgattttctgctgggcgatggcgggtttgcatctgtctaccgggcaact
tacaaatgtagagaagtggctgttaaaatttttaacaagcatgtgtcacagatgcaccta
caccgtctgctgagacaagaacttgcagttcttagttatctgcatcatcccagtttggtc
tctctattggcggctgactttcgacctcgaatgttggtaatggaattagcacccaaaggt
tccctggatctcttgcttaaccttgagaaagaccaccttaatcgaacacttcaacatcgg
attgctctacatgtggctgatggcttaagatacctccattcatcaatgataatatatagg
gatatgaagcctcacaatgtactgatgttcagtttgaatcctaactctgcgataattgct
aaaattgctgattatggaattgctcaatactgctgcagaatgggaatcaagagctctgag
ggcacaccaggatttcgagcaccagaagttgcaaagggaaatgtcatttataatcatcag
gctgatgtgtattcctttggattgcttttatatgatctgattactaatggtgaaagaatc
tcaattggaatgaagtttccaaatgactttgatgagatggcagttcagggaaagttgcca
gatccggtcaaagaatttaactgttctccgtggcctggtatccagactttaatcgatgat
tgtttgaaacaaaaccctgatgataggcctacagcttctcaggtgtatgacactctgaac
tcagtagagttactttgtttgaagagaaggatgatagtacccagtaatctcacagcagat
tgcatggtagctaccaactcaatttgcagaaagcctcgtgtctggattggcagtgggaaa
agagacaaggcacaactctcctgtttagaactggattcagatgttccggctgtcgtgaac
attgaggacaaccgcattttgtgcctggcactggtatgtgtgattggtgaagaagttaac
tgggttgttgctggtactcagtctggacatttgtggatagttaacacggagaatgtaaaa
tctgttcatcaacttcggaagatgtctgattctattacttgtttgttctgcacacatcat
tccaaacatagcaacgaagaacatttcctgttcgtggggacagcagatggcaaacttgcc
atttttaaggatacaacagtaaaatatgaagatggtgcacctctgaaggttgtggatata
ggtgacatcagtactcctttggtatgcctcagtgtttcttccacttcagaacaggtagtt
ttctgggcaagctgtggaacgaagatcgtatcactcagcagcgattttgcagttcagaag
gtgatagacacaaaaacaaggagtctaaaacaccaaaaatattacagtgatggaaatatt
atcacaatgataattgataaatatatttatctggcaaagaaggacagccacgttgttgaa
ctttgggacaaaaagtcatacaaaattagtgcgtcaattgattgtgcttctattcttaag
aatgacacgtattctgccagagtgaaagcacttcatcttcaaaaggcaacttgcctttgg
attggaacaggaggcggtgacgtcctattattagatctttccactcatcaacccatcctg
gtcattgataaatgttgtcattcaattagaagtatggtgacagcacaaattgaaaaggga
caccttcgcactgtcatgttgatcctaggaaatttctataaggattatgatgaaaacaac
aaacagcagagtggattgcaatcacagctgtttgtttgggacatgaatcttccttatgag
atccagaacctgaaaaagcacacagatatgagaagagaaatcattgaaaaaatgaggact
ggttcattggaatga
DBGET
integrated database retrieval system
