Streptomyces cavourensis: CVT27_13610
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Entry
CVT27_13610 CDS
T07023
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
scav
Streptomyces cavourensis
Pathway
scav00860
Porphyrin metabolism
scav01100
Metabolic pathways
scav01110
Biosynthesis of secondary metabolites
scav01120
Microbial metabolism in diverse environments
scav01240
Biosynthesis of cofactors
Module
scav_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
scav_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
scav_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
scav00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CVT27_13610
Enzymes [BR:
scav01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CVT27_13610
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CVT27_13610
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ATY96387
UniProt:
A0AAD0VEW0
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Position
complement(3110368..3112038)
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AA seq
556 aa
AA seq
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MSPTGPAASDFPPLSPRGQVTFLGAGPGDPGLLTLRAVEALASADVLVAEPDVLDVVRGH
ARAGVSTPELTVVDVASTTAGVPVLRDAANLVMEAAKGGRRVVRAVAGDPGLDGDAGAEM
LACAAAGVPFEVVPGVANAVGVPAYAGVPLRDAQGADVRFVDARTATDRCWSEVGASDAT
AVVSTTLDAVAAAAGELVSAGRKPDTPLTVTIAGTTTRQRTWTATLGTIAQVFKQAKVLP
SPEGHRPVIAVVGERSAAAQRDQLAWFESKPLFGWKVLVPRTKEQAASLSDQLRSYGAVP
HEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGI
KVAAVGEQTAAALVDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATE
TLVAGLIELGWEVDDVTAYRTVRASPPPADTREAIKGGGFDAVLFTSSSTVRNLVGIAGK
PHNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVHKLAEALAAFGTQRRDAAKEAGDPVT
RPSERRPGARRRRTTT
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccggccccgccgcatccgactttccgcccctgtccccccgaggtcaggtc
accttcctcggcgccggtcccggcgacccgggactgctgacgctgcgcgccgtcgaggcg
cttgcgagcgcggacgtccttgtcgccgagcccgatgtgctcgacgtcgttcgcggccat
gcgcgggcaggcgtgagcacgcctgagctgacggttgttgacgtggcgtcaacaaccgcc
ggagtacccgttctcagggatgccgccaatcttgtcatggaggccgcgaagggcggcagg
cgggtggtccgtgccgtggcgggcgacccgggcctggacggggacgcgggcgcggagatg
ctcgcctgcgccgccgccggggtgcccttcgaggtcgtcccgggcgtggcgaacgccgtc
ggcgtgcccgcgtacgccggagtgccgctgcgggacgcgcagggcgccgacgtccgcttc
gtcgacgcgcgtacggccaccgaccggtgctggagcgaggtcggcgcgagcgacgccacc
gccgtcgtctccaccacgctggacgcggtcgcggccgccgccggtgagctggtctcggcc
gggcgcaagcccgacaccccgctcacggtgacgatcgcgggcaccaccacccgccagcgc
acctggacggcgaccctcgggacgatcgcccaggtcttcaagcaggccaaggtgcttccc
tcgccggaggggcaccggccggtcatagccgtggtcggtgagcgcagtgccgccgcccag
cgcgaccagctcgcctggttcgagtcgaagccgctgttcggttggaaggtgctcgtcccg
cgcaccaaggagcaggccgcctcgctctccgaccagctgcgttcgtacggtgccgtgccg
cacgaggtcccgacgatcgccgtcgagccgccgcgtacgccccagcagatggagcgcgcg
gtcaagggcctggtcaccggccgctacgagtggatcgccttcaccagcgtcaacgccgtc
aaggcggtccgggagaagttcgaggagtacgggctcgacgcccgggccttcgccgggatc
aaggtcgcggccgtcggtgagcagaccgccgccgccctggtcgacttcggcgtcaagccg
gacctggtgccctccggtgagcagtccgccgccgggctgctggaggactggccgccctac
gacccggtcttcgacccgatcgaccgggtgttcctgccgcgcgccgacattgccaccgag
accctggtggccgggctgatcgagctgggctgggaggtcgacgacgtcaccgcgtaccgc
acggtccgcgcctcgccgccgccggccgacacccgcgaggcgatcaagggcggcggcttc
gacgcggtcctgttcacctcgtcctcgaccgtccggaacctggtcggcatcgcgggcaag
ccgcacaacgtgaccgtcatcgcgtgtatcggcccggccaccgcgaagaccgccgaggag
cacggcctgcgtgtggacgtcctctccccggagccgtccgtgcacaagctggccgaggcg
ctggccgccttcggtacgcagcggcgggacgcggcgaaggaggccggtgacccggtgacc
cggccgagcgagcgccgcccgggcgcacgcaggcgccggacgacgacgtaa
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