Streptomyces cathayae: PYS65_10635
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Entry
PYS65_10635 CDS
T09946
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
scay
Streptomyces cathayae
Pathway
scay00470
D-Amino acid metabolism
scay00550
Peptidoglycan biosynthesis
scay01100
Metabolic pathways
scay01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
scay00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
PYS65_10635
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
PYS65_10635
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
PYS65_10635
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
scay01011
]
PYS65_10635
Enzymes [BR:
scay01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
PYS65_10635
Peptidoglycan biosynthesis and degradation proteins [BR:
scay01011
]
Precursor biosynthesis
Amino acid ligase
PYS65_10635
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
WGD40566
UniProt:
A0ABY8K0X2
LinkDB
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Position
complement(2379964..2381121)
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AA seq
385 aa
AA seq
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MSTENLPQSPEQPPRKPRVAVVFGGRSSEHGISVVTAGAVLKAIDRTKYEVLPIGITQDG
RWALTADEPDRMAIVDRRQPSVDQLADSTEGAVLLPLDPGNREVVYSEPGSVPKALGEVD
VVFPVLHGPYGEDGTLQGLLELSGVPYVGSGVLASAVGQDKEYMKRVFTSFGLKVGPYVV
IRPRAWERDESAARKQIIDFAGEHGWPLFVKPARAGSSIGITKVDDLSGLDEAIAEAQRH
DPKILVEAALRGREIECGVLEFEDGPRASVPAEIPPPDAHAYYDFEAKYIDSTPGLVPAP
LTEEETAEVRRLAVEAFEAAGCEGLVRADFFLTEDGEFVINEINTMPGFTPISMYPKMWQ
ATGVEYPELVDRLVQAALRRPTGLR
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
atgagcaccgagaaccttccccagagccccgagcagccgccgcgcaagccgcgtgtggcc
gttgtgttcggcgggcgcagctccgagcacgggatctccgtggtcaccgccggcgccgtc
ctcaaggccatcgaccggaccaagtacgaggtcctgccgatcggcatcacccaggacggc
cggtgggcgctcaccgccgacgagccggaccgcatggccatcgtcgaccgtcggcagccc
agcgtggaccagctcgccgactcgaccgagggcgcggtgctgctccccctcgatcccggc
aaccgtgaagtcgtctacagcgagcccggttcggtgcccaaggcactcggcgaggtcgac
gtcgtcttcccggtgctgcacggcccctacggggaggacggcaccctgcagggtctcctg
gagctctccggcgtcccctacgtgggctccggggtgctggcctcggccgtcggccaggac
aaggagtacatgaagcgggtgttcacctccttcgggctgaaggtcggcccgtacgtggtg
atccggccgcgcgcatgggagcgcgacgagtccgccgcccgcaagcagatcatcgacttc
gccggtgagcacggctggccgttgttcgtgaagcccgcacgggcgggctcctcgatcggc
atcaccaaggtcgacgacctctccggcctggacgaggcgatcgccgaggcccagcggcac
gacccgaagatcctggtggaggcggccctgcgcggccgtgagatcgagtgcggcgtactg
gagttcgaggacggcccgcgtgcctcggtccccgccgagatcccgccgcccgacgcacac
gcctactacgacttcgaggccaagtacatcgactccacgcccggcctggtgcccgcaccg
ctgaccgaggaggagacggccgaggtgcgcaggctggcggtggaggcgttcgaggcggcc
ggctgcgagggactggtgcgcgcggacttcttcctcaccgaggacggcgagttcgtgatc
aacgagatcaacacgatgcccggcttcacacccatctcgatgtacccgaagatgtggcag
gccaccggtgtcgagtacccggagctggtggaccggctggtgcaggcggcgctccgccgc
ccgaccggactgcgctga
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