Streptomyces cathayae: PYS65_10675
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Entry
PYS65_10675 CDS
T09946
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
scay
Streptomyces cathayae
Pathway
scay00290
Valine, leucine and isoleucine biosynthesis
scay00660
C5-Branched dibasic acid metabolism
scay01100
Metabolic pathways
scay01110
Biosynthesis of secondary metabolites
scay01210
2-Oxocarboxylic acid metabolism
scay01230
Biosynthesis of amino acids
Module
scay_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
scay00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
PYS65_10675 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
PYS65_10675 (leuC)
Enzymes [BR:
scay01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
PYS65_10675 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
PYS65_10675 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
WGD40574
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Position
complement(2386117..2387544)
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AA seq
475 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKSGRGVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRVQLETLRANCAEFGVRLHSLGDVEQGVVHVVGPQLGLTQP
GMTVVCGDSHTSTHGAFGGLAFGIGTSQVEHVLATQTLPMTRPKTMAITVEGELPDGVTA
KDLILAVIARIGTGGGQGYVLEYRGEAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLEGRPHAPRGEDWDAAVAYWKTLRTDQDAEFDAEVVIDAAALSPFVTWGTNPGQGAPL
SADVPDPAAYEDASERLAAEKALEYMGLTAGQPLRSIGVDTVFVGSCTNGRIEDLRAAAD
IVRGRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERCASTSNRNFEGRQGKGGRTHLVSPQVAAATALLGHLASPADLDADAPTPAGV
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactggcggagaaggtctgggacgaccatgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggcctgcgcaagagcggccgcggggtgcgccggctcgacctgaccatcgcgacc
gaggaccacaacaccccgaccctggacatcgacaagcccatcgccgacccggtctcccgg
gtccagctggagacgctgcgggcgaactgcgcggagttcggtgtccggctgcactcgctg
ggcgacgtcgagcagggcgtcgtgcacgtggtggggccacagctggggctgacccagccc
ggcatgaccgtggtctgcggggactcgcacacctccacgcacggcgcgttcggcggcctg
gccttcggtatcggcacctcccaggtcgagcacgtgctggccacccagaccctgccgatg
acccgccccaagaccatggcgatcactgtcgagggcgaactgcccgacggggtcacggcc
aaggacctgatcctggcggtcatcgcgcggatcggcaccggcggcggccagggctacgtc
ctggagtaccgcggcgaggccatcgagaagctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagaccacgttc
gcctacctcgagggccgcccgcacgccccgcggggcgaggactgggacgcggccgtggcc
tactggaagacgttgcgcaccgaccaggacgccgagttcgacgccgaggtcgtcatcgac
gccgccgcgctgtcgccgttcgtcacctggggcaccaaccccggccagggcgctccgctg
tcggccgacgtgcccgaccccgccgcctacgaagacgcctcggagcgcctggccgccgaa
aaggccctggaatacatggggttgacggccggccagccgctgcgctccatcggtgtggac
accgtgttcgtaggttcctgcaccaacggccggatcgaggacctgcgcgccgccgccgac
atcgtcaggggccgcaaagtcgccgacggcgtacggatgctggtcgtccccggctccgcc
cgggtgggcctgcaggccgtctccgagggcctggacgtggtcttcaaggaggcgggcgcc
gagtggcggcacgcgggctgctcgatgtgcctgggcatgaaccccgaccagctcgccccc
ggtgagcgctgcgcctccacctccaaccgcaacttcgagggccggcagggcaagggcggc
cgtacccacctggtctccccccaggtcgccgccgccaccgcgctcctcggccacctggcc
tccccggccgacctcgacgccgacgcccccacgcccgctggagtctga
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